Development Level

Tbio 16 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal skin morphology 1 | 50
abnormal tooth morphology 1 | 24
decreased circulating insulin ... 1 | 76
decreased circulating lipase l... 1 | 3
decreased circulating sodium l... 1 | 22
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 15 | 11,493
Breast cancer 12 | 3,578
Autosomal recessive predisposition 11 | 1,442
non-small cell lung cancer 11 | 2,890
Epidermolysis bullosa 10 | 21
pancreatic cancer 10 | 2,398
Atrophic scar 9 | 18
Dystrophia unguium 9 | 53
Nail dysplasia 9 | 52
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
ANONYCHIA 8 | 20
Anemia 8 | 365
Bullous pemphigoid 8 | 18
Dental Enamel Hypoplasia 8 | 43
Dental caries 8 | 164
Kidney cancer 8 | 2,613
Milium Cyst 8 | 16
Oral mucosal blistering 8 | 10
esophageal adenocarcinoma 8 | 737
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
malignant mesothelioma 8 | 3,232
Aplasia Cutis Congenita 7 | 14
Cancer 7 | 2,499
Congenital scar 7 | 13
Defective enamel matrix 7 | 35
Dysplasia of tooth enamel 7 | 35
Failure to gain weight 7 | 365
Hemoglobin low 7 | 124
Pediatric failure to thrive 7 | 365
Prenatal onset 7 | 139
Rotting teeth 7 | 73
Thin dental enamel 7 | 35
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
ovarian cancer 7 | 8,520
Abnormal blistering of the skin 6 | 54
Blister of skin 6 | 54
Death in early childhood 6 | 82
Death in infancy 6 | 82
Fragile nails 6 | 16
Junctional split 6 | 6
Plantar hyperkeratosis 6 | 7
Scarring alopecia of scalp 6 | 13
Skin Erosion 6 | 12
Skin bulla 6 | 54
breast carcinoma 6 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung carcinoma 6 | 2,843
Abnormal pigmentation 5 | 25
Adult junctional epidermolysis bullosa (disorder) 5 | 5
Dehydration 5 | 40
Epidermolysis Bullosa, Junctional, Non-Herlitz Type 5 | 5
Flexion contracture of proximal interphalangeal joint 5 | 75
Hypodontia 5 | 81
Junctional epidermolysis bullosa 5 | 7
Palmar hyperhidrosis 5 | 5
Sparse body hair 5 | 32
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
Dermatitis 4 | 157
Epidermolysis Bullosa, Junctional 4 | 4
Feeding difficulties 4 | 127
Fragile skin 4 | 18
Keratosis 4 | 37
Lichen planus 4 | 16
Liver cancer 4 | 604
Recurrent skin infections 4 | 21
Rheumatoid arthritis 4 | 1,191
cutaneous lupus erythematosus 4 | 1,057
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Alopecia 3 | 115
Arthrogryposis 3 | 54
Axillary pterygia 3 | 6
Barrett's esophagus 3 | 182
Down syndrome 3 | 499
Dyspnea 3 | 76
Esophageal Stenosis 3 | 15
Esophageal atresia 3 | 43
Hoarseness 3 | 31
Hydronephrosis 3 | 89
Laryngismus 3 | 3
Laryngostenosis 3 | 10
Melanoma 3 | 711
Palmoplantar keratosis 3 | 74
Paronychia Inflammation 3 | 9
Polyhydramnios 3 | 108
Pyloric Stenosis 3 | 47
RENAL ADYSPLASIA 3 | 25
Renal dysplasia 3 | 28
Urethral Stricture 3 | 18
nasopharyngeal carcinoma 3 | 1,058
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Skin and soft tissues 16 | 17,230
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Urinary Tract 15 | 16,678
Respiratory system 14 | 16,393
Liver and Pancreas 13 | 16,750
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 1 | 4,145

Compartment GO Term

Hemidesmosome 17 | 17
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.75473 576.3 123
Desmoplakin DSP Tbio Non-IDG -2.95735 853.9 198
Keratin, type II cytoskeletal 3 KRT3 Tbio Non-IDG -2.15644 132.3 116
Keratin, type I cytoskeletal 14 KRT14 Tbio Non-IDG -2.90790 721.6 780
Epiplakin EPPK1 Tdark Non-IDG -1.29990 21.1 0
Dystonin DST Tbio Non-IDG -2.73231 506.0 127
Plectin PLEC Tbio Non-IDG -2.50749 337.2 130
Integrin beta-4 ITGB4 Tbio Non-IDG -2.26591 177.4 704
Filaggrin FLG Tbio Non-IDG -3.03594 1055.2 253
Erbin ERBIN Tbio Non-IDG -1.72357 59.1 117