Development Level

Tbio 6 | 11,651
Tchem 2 | 1,388

IMPC Phenotype

increased mean corpuscular hem... 2 | 96
abnormal embryo size 1 | 220
abnormal skin morphology 1 | 50
decreased erythrocyte cell num... 1 | 62
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
increased circulating iron lev... 1 | 30
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74

Disease

Carcinoma 8 | 11,493
Anemia 7 | 365
Hemochromatosis 6 | 54
ovarian cancer 6 | 8,520
Autosomal recessive predisposition 5 | 1,442
Cancer 5 | 2,499
Thalassemia 5 | 53
atypical teratoid / rhabdoid tumor 5 | 5,112
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
Alzheimer's disease 4 | 658
Atransferrinemia 4 | 8
Breast cancer 4 | 3,578
Liver disease 4 | 237
ependymoma 4 | 4,679
medulloblastoma, large-cell 4 | 6,241
Aceruloplasminemia 3 | 16
Arthropathy 3 | 43
Astrocytoma, Pilocytic 3 | 3,081
Hemochromatosis type 1 3 | 9
Iron deficiency anemia 3 | 12
Iron metabolism disease 3 | 20
Kidney disease 3 | 430
Neurodegenerative disease 3 | 414
Peripheral vascular disease 3 | 87
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
diabetes mellitus 3 | 1,728
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
pituitary cancer 3 | 1,972
Alzheimer Disease 2 | 83
Arthritis 2 | 290
Beta thalassemia 2 | 16
Cholestasis 2 | 155
Congestive heart failure 2 | 113
Craniofacial Abnormalities 2 | 151
Decreased joint mobility 2 | 53
Elevated hepatic transaminases 2 | 81
Essential Hypertension 2 | 94
Eye Abnormalities 2 | 35
Fatty liver disease 2 | 103
Fibrodysplasia ossificans progressiva 2 | 17
Heart failure 2 | 162
Hemoglobin low 2 | 124
Hemolytic anemia 2 | 77
Hepatic enzyme increased 2 | 81
Hepatitis C 2 | 94
Hepatomegaly 2 | 285
Hyperferritinaemia 2 | 14
Hyperpigmentation 2 | 37
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Hypoalbuminemia 2 | 24
Hypogonadism 2 | 173
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Increased ferritin 2 | 14
Inflammation 2 | 120
Kidney cancer 2 | 2,613
Liver Cirrhosis 2 | 181
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Lung disease 2 | 142
Malaria 2 | 160
Nephrotic Syndrome 2 | 78
Obesity 2 | 678
Porphyria cutanea tarda 2 | 12
Prostatic Neoplasms 2 | 495
Schizoaffective Disorder 2 | 55
Serum ferritin increased 2 | 14
Short ulnae 2 | 24
Siderosis 2 | 9
Splenomegaly 2 | 190
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
ULNAR HYPOPLASIA 2 | 24
beta-Thalassemia 2 | 10
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
non diabetic and post-ischemic heart failure 2 | 200
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 162
ulcerative colitis 2 | 1,819
Polyposis, Gastric 1 | 4

Tissue

Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Liver and Pancreas 8 | 16,750
Nervous System 8 | 16,725
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Female tissues 7 | 17,400
Male tissues 7 | 17,142
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Respiratory system 6 | 16,393

Target Family

Non-IDG 5 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145

Compartment GO Term

HFE-transferrin receptor compl... 8 | 8
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transferrin receptor protein 2 TFR2 Tbio Enzyme -2.11882 135.2 149
Hereditary hemochromatosis protein HFE Tbio Non-IDG -3.32815 2229.5 248
Hemojuvelin HFE2 Tbio Non-IDG -2.16845 146.9 284
Beta-2-microglobulin B2M Tbio Non-IDG -3.90978 7800.2 1448
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -2.00303 86.8 498