Development Level

Tclin 4 | 613
Tbio 2 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal allantois morphology 1 | 8
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
bleb 1 | 2
decreased fasted circulating g... 1 | 65
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
increased fasted circulating g... 1 | 76
pale yolk sac 1 | 25
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
Atrial Fibrillation 3 | 124
Paroxysmal atrial fibrillation 3 | 14
atypical teratoid / rhabdoid tumor 3 | 5,112
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
3-M syndrome 2 | 15
Angina Pectoris 2 | 32
Chronic heart failure 2 | 46
Long QT syndrome 2 | 39
Obesity 2 | 678
Sick sinus syndrome 2 | 15
Sinoatrial node disease 2 | 5
glioblastoma 2 | 5,792
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
Abnormality of retinal pigmentation 1 | 111
Abnormality of the retinal vasculature 1 | 59
Anteverted nostril 1 | 191
Atrioventricular Septal Defect 1 | 22
Atrioventricular block 1 | 35
Atypical scarring of skin 1 | 62
Autosomal recessive predisposition 1 | 1,442
Blind Vision 1 | 111
Blindness, Legal 1 | 110
Broad flat nasal bridge 1 | 236
Brugada Syndrome (disorder) 1 | 15
Brugada Syndrome 8 1 | 1
Brugada syndrome 1 | 29
Cardiomyopathy 1 | 116
Cataract 1 | 297
Chromosome 15q24 deletion syndrome 1 | 12
Conductive hearing loss 1 | 123
Congenital anomaly of testis 1 | 52
Congenital hypoplasia of penis 1 | 176
Diabetic autonomic neuropathy 1 | 3
Difficulties with night vision 1 | 87
Dull intelligence 1 | 645
Electroretinogram abnormal 1 | 95
Endocardial Fibroelastosis 1 | 9
Glaucoma 1 | 239
Heart conduction disease 1 | 83
Heart disease 1 | 306
Hydronephrosis 1 | 89
Hyperinsulinism 1 | 133
Hypogonadism 1 | 173
Intellectual disability 1 | 1,016
Keratoconus 1 | 113
Kidney cancer 1 | 2,613
Left ventricular noncompaction 1 | 26
Lens Opacities 1 | 231
Long Qt Syndrome 2 1 | 5
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental deficiency 1 | 645
Mood Disorders 1 | 184
Nasal bridge wide 1 | 236
Night Blindness 1 | 101
Night blindness, progressive 1 | 51
Nystagmus 1 | 317
Ophthalmoplegia 1 | 106
Optic Atrophy 1 | 242
Pallister-Hall syndrome 1 | 10
Photodysphoria 1 | 121
Photophobia 1 | 121
Poor school performance 1 | 645
Prenatal onset 1 | 139
Renal tuberculosis 1 | 4
Retinal pigment epithelial abnormality 1 | 111
Retinitis Pigmentosa 1 | 226
Retinitis pigmentosa 49 1 | 14
Right bundle branch block 1 | 17
ST segment elevation (finding) 1 | 3
Sensorineural Hearing Loss (disorder) 1 | 284
Sick Sinus Syndrome 2 1 | 1
Sick Sinus Syndrome 2, Autosomal Dominant 1 | 1
Sinus bradycardia 1 | 7
Tachycardia, Ventricular 1 | 22
Visual field constriction 1 | 36
active Crohn's disease 1 | 922
adult high grade glioma 1 | 3,801
aldosterone-producing adenoma 1 | 665
cutaneous lupus erythematosus 1 | 1,057
ependymoma 1 | 4,679
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
interstitial cystitis 1 | 2,312
lung carcinoma 1 | 2,843
non-small cell lung cancer 1 | 2,890
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
sonic hedgehog group medulloblastoma 1 | 467
spina bifida 1 | 1,074
ulcerative colitis 1 | 1,819
ventricular septal defect 1 | 20

Tissue

Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Blood and immune system 6 | 16,909
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Ion Channel 4 | 344
Enzyme 3 | 4,145

Compartment GO Term

HCN2 channel complex 7 | 7
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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