Development Level

Tclin 4 | 612
Tbio 2 | 11,178
Tchem 1 | 1,885

IMPC Phenotype

abnormal allantois morphology 1 | 8
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
bleb 1 | 2
decreased fasted circulating g... 1 | 65
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
increased fasted circulating g... 1 | 76
pale yolk sac 1 | 25
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,192
Atrial Fibrillation 3 | 120
Paroxysmal atrial fibrillation 3 | 14
atypical teratoid / rhabdoid tumor 3 | 4,971
osteosarcoma 3 | 7,766
psoriasis 3 | 6,514
3-M syndrome 2 | 15
Angina Pectoris 2 | 32
Chronic heart failure 2 | 44
Long QT syndrome 2 | 39
Obesity 2 | 655
Sick sinus syndrome 2 | 15
Sinoatrial node disease 2 | 5
glioblastoma 2 | 5,635
lung cancer 2 | 4,607
medulloblastoma, large-cell 2 | 6,086
pediatric high grade glioma 2 | 1,035
primitive neuroectodermal tumor 2 | 2,957
Abnormality of retinal pigmentation 1 | 109
Abnormality of the retinal vasculature 1 | 58
Anteverted nostril 1 | 186
Atrioventricular Septal Defect 1 | 22
Atrioventricular block 1 | 35
Atypical scarring of skin 1 | 61
Autosomal recessive predisposition 1 | 1,407
Blind Vision 1 | 110
Blindness, Legal 1 | 109
Broad flat nasal bridge 1 | 232
Brugada Syndrome (disorder) 1 | 14
Brugada Syndrome 8 1 | 1
Brugada syndrome 1 | 28
Cardiomyopathy 1 | 116
Cataract 1 | 290
Chromosome 15q24 deletion syndrome 1 | 12
Conductive hearing loss 1 | 122
Congenital anomaly of testis 1 | 51
Congenital hypoplasia of penis 1 | 168
Diabetic autonomic neuropathy 1 | 3
Difficulties with night vision 1 | 85
Dull intelligence 1 | 634
Electroretinogram abnormal 1 | 94
Endocardial Fibroelastosis 1 | 9
Glaucoma 1 | 232
Heart conduction disease 1 | 82
Heart disease 1 | 288
Hydronephrosis 1 | 87
Hyperinsulinism 1 | 128
Hypogonadism 1 | 169
Intellectual disability 1 | 998
Keratoconus 1 | 111
Kidney cancer 1 | 2,548
Left ventricular noncompaction 1 | 26
Lens Opacities 1 | 227
Long Qt Syndrome 2 1 | 5
Low intelligence 1 | 634
Mental Retardation 1 | 634
Mental deficiency 1 | 634
Mood Disorders 1 | 181
Nasal bridge wide 1 | 232
Night Blindness 1 | 99
Night blindness, progressive 1 | 50
Nystagmus 1 | 309
Ophthalmoplegia 1 | 105
Optic Atrophy 1 | 239
Pallister-Hall syndrome 1 | 10
Photodysphoria 1 | 117
Photophobia 1 | 117
Poor school performance 1 | 634
Prenatal onset 1 | 137
Renal tuberculosis 1 | 4
Retinal pigment epithelial abnormality 1 | 109
Retinitis Pigmentosa 1 | 223
Retinitis pigmentosa 49 1 | 14
Right bundle branch block 1 | 17
ST segment elevation (finding) 1 | 3
Sensorineural Hearing Loss (disorder) 1 | 281
Sick Sinus Syndrome 2 1 | 1
Sick Sinus Syndrome 2, Autosomal Dominant 1 | 1
Sinus bradycardia 1 | 7
Tachycardia, Ventricular 1 | 22
Visual field constriction 1 | 35
active Crohn's disease 1 | 882
adult high grade glioma 1 | 3,701
aldosterone-producing adenoma 1 | 646
cutaneous lupus erythematosus 1 | 1,016
ependymoma 1 | 4,559
group 3 medulloblastoma 1 | 4,002
group 4 medulloblastoma 1 | 1,806
interstitial cystitis 1 | 2,237
lung carcinoma 1 | 2,755
non-small cell lung cancer 1 | 2,799
pituitary cancer 1 | 1,915
posterior fossa group A ependymoma 1 | 456
sonic hedgehog group medulloblastoma 1 | 459
spina bifida 1 | 1,053
ulcerative colitis 1 | 1,765
ventricular septal defect 1 | 20

Tissue

Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Blood and immune system 6 | 16,909
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Ion Channel 4 | 344
Enzyme 3 | 4,145

Compartment GO Term

HCN2 channel complex 7 | 7
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

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