Development Level

Tbio 33 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased body weight 4 | 161
abnormal behavior 3 | 298
abnormal cornea morphology 3 | 31
abnormal lens morphology 3 | 81
embryonic lethality prior to t... 3 | 278
abnormal eye morphology 2 | 68
cataract 2 | 92
corneal opacity 2 | 32
decreased circulating glucose ... 2 | 126
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
tremors 2 | 39
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye pigmentation 1 | 3
abnormal eye size 1 | 7
abnormal eyelid aperture 1 | 2
abnormal iris morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal retinal blood vessel ... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal tooth morphology 1 | 24
abnormal vertebral arch morpho... 1 | 9
corneal vascularization 1 | 6
decreased IgG2b level 1 | 4
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased cardiac stroke volum... 1 | 6
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
eyelids fail to open 1 | 3
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 42
increased lactate dehydrogenas... 1 | 3
increased respiratory quotient 1 | 2
irregularly shaped pupil 1 | 7
mydriasis 1 | 6
thrombocytopenia 1 | 56

Disease

Carcinoma 30 | 11,493
ovarian cancer 28 | 8,520
osteosarcoma 23 | 7,950
Breast cancer 13 | 3,578
glioblastoma 13 | 5,792
lung cancer 13 | 4,740
malignant mesothelioma 13 | 3,232
group 3 medulloblastoma 12 | 4,104
medulloblastoma, large-cell 12 | 6,241
psoriasis 12 | 6,694
Cancer 11 | 2,499
atypical teratoid / rhabdoid tumor 10 | 5,112
Kidney cancer 9 | 2,613
ependymoma 9 | 4,679
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
oligodendroglioma 8 | 2,850
Multiple myeloma 7 | 1,332
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Rheumatoid arthritis 6 | 1,191
pancreatic cancer 6 | 2,398
adult high grade glioma 5 | 3,801
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
tuberculosis 5 | 2,010
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
hepatocellular carcinoma 4 | 547
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
non primary Sjogren syndrome sicca 4 | 891
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Aicardi syndrome 3 | 14
Alzheimer's disease 3 | 658
Endometriosis 3 | 540
Intellectual disability 3 | 1,016
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
Spinocerebellar ataxia type 7 3 | 13
Thrombocytopenia 3 | 197
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
cystic fibrosis 3 | 1,696
gastric cancer 3 | 459
juvenile dermatomyositis 3 | 1,187
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
Acquired scoliosis 2 | 281
Adenoid Cystic Carcinoma 2 | 99
Autoimmune thrombocytopenic purpura 2 | 13
Autosomal recessive predisposition 2 | 1,442
Carcinoma, Adenoid Cystic 2 | 99
Cerebrovascular disease 2 | 238
Cleft Lip 2 | 141
Cleft Palate 2 | 271
Coronary artery disease 2 | 268
Craniofacial Abnormalities 2 | 151
Curvature of spine 2 | 282
Down syndrome 2 | 499
Ecchymosis 2 | 66
Endometrial cancer 2 | 311
FNAITP 2 | 6
Focal dermal hypoplasia 2 | 8
Increased tendency to bruise 2 | 66
Koolen de Vries syndrome 2 | 18
Liver cancer 2 | 604
Muscle hypotonia 2 | 571
Orbital separation excessive 2 | 244
Purpura 2 | 43
Sensorineural Hearing Loss (disorder) 2 | 284
Short stature 2 | 531
Vascular disease 2 | 319
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
ductal carcinoma in situ 2 | 1,745
inflammatory breast cancer 2 | 286
medulloblastoma 2 | 720
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Agenesis of teeth 1 | 21
Cardiomyopathy, Hypertrophic 1 | 24
Chromosome 17 deletion 1 | 2
Endometrial stromal sarcoma 1 | 15
Fundus coloboma 1 | 18
Hamman-Rich syndrome 1 | 34
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 8
Mild Mental Retardation 1 | 70
Ollier disease 1 | 18
Ossifying fibromyxoid tumor 1 | 5
Reduced number of teeth 1 | 21
Type 1 diabetes mellitus 1 | 109
Von Hippel-Lindau disease 1 | 19

Tissue

Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 26 | 12,091
Epigenetic 9 | 242
Enzyme 5 | 4,145
Kinase 1 | 634

Compartment GO Term

H4 histone acetyltransferase c... 41 | 41
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
Integrin alpha-IIb ITGA2B Tclin Non-IDG -3.52120 3309.8 1170
Histone H4 HIST2H4A Tbio Non-IDG -2.67437 144.5 913
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Histone acetyltransferase KAT5 KAT5 Tchem Epigenetic -2.29449 194.7 504
Histone acetyltransferase KAT2B KAT2B Tchem Epigenetic -2.62847 372.0 331
YEATS domain-containing protein 4 YEATS4 Tbio Non-IDG -1.42145 30.1 311
WD repeat-containing protein 5 WDR5 Tchem Non-IDG -2.10077 115.4 299
Actin-like protein 6A ACTL6A Tbio Non-IDG -1.45479 28.3 286