Development Level

Tbio 15 | 11,445
Tchem 11 | 1,598
Tclin 9 | 613

IMPC Phenotype

enlarged heart 3 | 210
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal duodenum morphology 1 | 4
abnormal gait 1 | 69
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased monocyte cell number 1 | 8
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged spleen 1 | 41
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 25 | 11,493
Hypertension 20 | 396
ovarian cancer 17 | 8,520
adult high grade glioma 15 | 3,801
medulloblastoma, large-cell 15 | 6,241
psoriasis 15 | 6,694
Kidney cancer 14 | 2,613
ependymoma 14 | 4,679
lung cancer 14 | 4,740
osteosarcoma 14 | 7,950
Breast cancer 13 | 3,578
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
lung carcinoma 13 | 2,843
Astrocytoma, Pilocytic 12 | 3,081
diabetes mellitus 12 | 1,728
Cancer 11 | 2,499
Heart disease 11 | 306
group 3 medulloblastoma 11 | 4,104
ulcerative colitis 11 | 1,819
Autosomal recessive predisposition 10 | 1,442
Coronary artery disease 10 | 268
Hypertensive disease 10 | 292
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
non-small cell lung cancer 10 | 2,890
primitive neuroectodermal tumor 10 | 3,035
astrocytic glioma 9 | 2,597
Cerebrovascular disease 8 | 238
breast carcinoma 8 | 1,638
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
pancreatic cancer 8 | 2,398
Asthma 7 | 385
Kidney disease 7 | 430
Pulmonary hypertension 7 | 85
gastric carcinoma 7 | 807
interstitial cystitis 7 | 2,312
invasive ductal carcinoma 7 | 2,951
subependymal giant cell astrocytoma 7 | 2,287
Acute kidney injury 6 | 70
Alzheimer's disease 6 | 658
Cardiomegaly 6 | 116
Depressive disorder 6 | 409
Epilepsy 6 | 792
Heart failure 6 | 162
Impotence 6 | 42
Liver Cirrhosis, Experimental 6 | 769
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
Ureteral obstruction 6 | 33
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
oligodendroglioma 6 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pituitary cancer 6 | 1,972
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Melanoma 5 | 711
Mental Depression 5 | 333
Toxic encephalopathy 5 | 141
Acquired metabolic disease 4 | 336
Atherosclerosis 4 | 291
Atrial Fibrillation 4 | 124
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Chronic heart failure 4 | 46
Decompensated cardiac failure 4 | 9
Diabetes Mellitus, Experimental 4 | 108
Diabetic Angiopathies 4 | 16
Hyperalgesia 4 | 83
Lung disease 4 | 142
Mammary Neoplasms 4 | 425
Mood Disorders 4 | 184
Myocardial Ischemia 4 | 169
Myocardial Reperfusion Injury 4 | 37
Obesity 4 | 678
Pain 4 | 103
Reperfusion Injury 4 | 86
Status Epilepticus 4 | 98
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic carcinoma 4 | 562
Brain Ischemia 3 | 110
Cerebrovascular accident 3 | 63
Essential Hypertension 3 | 94
Liver Cirrhosis 3 | 181
Lung Neoplasms 3 | 232
Major Depressive Disorder 3 | 301
Peripheral vascular disease 3 | 87
Seizures 3 | 596
Stomach Neoplasms 3 | 300
Unipolar Depression 3 | 250
atypical teratoid/rhabdoid tumor 3 | 357
chronic rhinosinusitis 3 | 512
cystic fibrosis 3 | 1,696
head and neck cancer 3 | 271
medulloblastoma 3 | 720
tuberculosis 3 | 2,010

Tissue

Endocrine System 35 | 18,159
Blood and immune system 34 | 16,909
Digestive Tract 34 | 17,369
Female tissues 34 | 17,400
Male tissues 34 | 17,142
Skin and soft tissues 34 | 17,230
Nervous System 32 | 16,725
Urinary Tract 32 | 16,678
Liver and Pancreas 31 | 16,750
Respiratory system 31 | 16,393
Cardiovascular System 30 | 15,192

Target Family

Enzyme 20 | 4,145
Non-IDG 9 | 12,091
Kinase 6 | 634

Compartment GO Term

Guanylate cyclase complex, sol... 35 | 35
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.35296 2270.4 122
Heat-stable enterotoxin receptor GUCY2C Tclin Kinase -2.33494 214.5 228
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Retinal guanylyl cyclase 2 GUCY2F Tbio Kinase -1.00236 7.60 84
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.61657 45.3 134
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752