Development Level

Tbio 69 | 11,445
Tchem 34 | 1,598
Tclin 18 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 5 | 278
enlarged heart 4 | 210
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal femur morphology 2 | 14
abnormal lung morphology 2 | 26
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
impaired pupillary reflex 2 | 26
increased bone mineral content 2 | 108
limb grasping 2 | 41
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
cleft palate 1 | 8
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73
decreased spleen weight 1 | 10
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
female infertility 1 | 60
fused cornea and lens 1 | 5
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
iris synechia 1 | 3
male infertility 1 | 123
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
small superior vagus ganglion 1 | 74

Disease

Cancer 109 | 2,499
ovarian cancer 78 | 8,520
Carcinoma 75 | 11,493
glioblastoma 72 | 5,792
psoriasis 69 | 6,694
lung cancer 68 | 4,740
malignant mesothelioma 66 | 3,232
diabetes mellitus 64 | 1,728
osteosarcoma 59 | 7,950
Breast cancer 57 | 3,578
ependymoma 54 | 4,679
cystic fibrosis 52 | 1,696
invasive ductal carcinoma 51 | 2,951
Kidney disease 48 | 430
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,955
Astrocytoma, Pilocytic 46 | 3,081
Breast Neoplasms 46 | 445
Mammary Neoplasms 46 | 425
atypical teratoid / rhabdoid tumor 46 | 5,112
interstitial cystitis 46 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 46 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,291
lung adenocarcinoma 46 | 2,716
non-small cell lung cancer 46 | 2,890
pancreatic cancer 44 | 2,398
lung carcinoma 42 | 2,843
medulloblastoma, large-cell 40 | 6,241
Liver Cirrhosis, Experimental 39 | 769
ulcerative colitis 39 | 1,819
Hypertension 38 | 396
ductal carcinoma in situ 38 | 1,745
Heart disease 37 | 306
adult high grade glioma 37 | 3,801
pituitary cancer 37 | 1,972
Schizophrenia 35 | 1,160
breast carcinoma 35 | 1,638
Atherosclerosis 34 | 291
Obesity 34 | 678
Vascular disease 32 | 319
Liver disease 31 | 237
oligodendroglioma 31 | 2,850
Prostatic Neoplasms 30 | 495
adrenocortical carcinoma 30 | 1,428
Arthritis 29 | 290
tuberculosis 28 | 2,010
Alzheimer's disease 27 | 658
Cerebrovascular disease 27 | 238
Coronary artery disease 27 | 268
Hypertensive disease 27 | 292
Pulmonary Fibrosis 27 | 106
Stomach Neoplasms 27 | 300
Lung disease 26 | 142
Osteoporosis 26 | 363
group 3 medulloblastoma 26 | 4,104
Carcinoma, Hepatocellular 25 | 228
Diabetic retinopathy 25 | 56
Liver carcinoma 25 | 240
primitive neuroectodermal tumor 25 | 3,035
Depressive disorder 24 | 409
Liver Cirrhosis 24 | 181
gastric carcinoma 24 | 807
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
Anemia 23 | 365
Asthma 23 | 385
Endometriosis 23 | 540
Hypersensitivity reaction type II disease 23 | 253
Kidney cancer 23 | 2,613
Lung Neoplasms 23 | 232
colon cancer 23 | 1,478
primary pancreatic ductal adenocarcinoma 23 | 1,109
Hyperglycemia 22 | 137
Neoplasm Metastasis 22 | 168
Rheumatoid arthritis 22 | 1,191
group 4 medulloblastoma 22 | 1,855
Major Depressive Disorder 21 | 301
Short stature 21 | 531
astrocytic glioma 21 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 21 | 510
Autosomal recessive predisposition 20 | 1,442
Cleft Palate 20 | 271
Unipolar Depression 20 | 250
Inflammation 19 | 120
Neoplasm Invasiveness 19 | 161
Osteoarthritis 19 | 184
Reperfusion Injury 19 | 86
Adenocarcinoma 18 | 122
Atopic dermatitis 18 | 952
Bipolar Disorder 18 | 666
Polycystic ovary syndrome 18 | 360
Down syndrome 17 | 499
Duchenne muscular dystrophy 17 | 601
Eye disease 17 | 62
Hypoplastic mandible condyle 17 | 275
Mandibular hypoplasia 17 | 275
Mental Depression 17 | 333
Micrognathism 17 | 275
Myocardial Ischemia 17 | 169
Seizures 17 | 596
cutaneous lupus erythematosus 17 | 1,057
subependymal giant cell astrocytoma 17 | 2,287

Tissue

Endocrine System 119 | 18,159
Blood and immune system 117 | 16,909
Digestive Tract 117 | 17,369
Female tissues 117 | 17,400
Male tissues 116 | 17,142
Respiratory system 116 | 16,393
Skin and soft tissues 116 | 17,230
Liver and Pancreas 115 | 16,750
Nervous System 114 | 16,725
Urinary Tract 114 | 16,678
Cardiovascular System 109 | 15,192

Target Family

Non-IDG 87 | 12,091
Kinase 13 | 634
Transcription Factor 11 | 1,400
Enzyme 10 | 4,145

Compartment GO Term

Growth factor complex 121 | 121
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Pappalysin-2 PAPPA2 Tbio Non-IDG -1.39571 27.8 113
Serum albumin ALB Tchem Non-IDG -5.01233 98804.9 2101
Transforming growth factor beta-3 TGFB3 Tbio Non-IDG -3.02749 1062.5 308