Development Level

Tbio 110 | 11,445
Tchem 21 | 1,598
Tdark 6 | 6,588
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal behavior 9 | 298
abnormal bone structure 8 | 187
preweaning lethality, incomple... 8 | 499
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
decreased total body fat amoun... 5 | 207
embryonic lethality prior to o... 5 | 239
short tibia 5 | 97
decreased circulating choleste... 4 | 93
decreased circulating serum al... 4 | 82
decreased vertical activity 4 | 208
increased circulating alkaline... 4 | 122
increased fasted circulating g... 4 | 76
increased lean body mass 4 | 172
abnormal locomotor behavior 3 | 24
decreased body weight 3 | 161
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased circulating total pr... 3 | 49
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
decreased lymphocyte cell numb... 3 | 83
impaired glucose tolerance 3 | 75
increased circulating chloride... 3 | 41
increased red blood cell distr... 3 | 34
prenatal lethality prior to he... 3 | 87
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo turning 2 | 31
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
cataract 2 | 92
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 47
decreased circulating alkaline... 2 | 46
decreased circulating aspartat... 2 | 34
decreased circulating insulin ... 2 | 76
decreased pulmonary respirator... 2 | 5
enlarged heart 2 | 210
enlarged kidney 2 | 14
enlarged stomach 2 | 2
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating amylase ... 2 | 25
increased neutrophil cell numb... 2 | 46
increased prepulse inhibition 2 | 32
increased total body fat amoun... 2 | 134
pallor 2 | 34
polycystic kidney 2 | 15
small thymus 2 | 16
tremors 2 | 39
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal retinal inner nuclear... 1 | 8
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged adrenal glands 1 | 3
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
limb grasping 1 | 41
respiratory system phenotype 1 | 2
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 115 | 11,493
medulloblastoma, large-cell 86 | 6,241
atypical teratoid / rhabdoid tumor 83 | 5,112
glioblastoma 83 | 5,792
ovarian cancer 79 | 8,520
ependymoma 73 | 4,679
adult high grade glioma 71 | 3,801
osteosarcoma 64 | 7,950
Astrocytoma, Pilocytic 57 | 3,081
psoriasis 57 | 6,694
oligodendroglioma 56 | 2,850
group 3 medulloblastoma 54 | 4,104
lung cancer 52 | 4,740
astrocytic glioma 50 | 2,597
Cancer 47 | 2,499
Kidney cancer 46 | 2,613
Breast cancer 45 | 3,578
lung carcinoma 42 | 2,843
malignant mesothelioma 41 | 3,232
subependymal giant cell astrocytoma 38 | 2,287
Pick disease 37 | 1,894
Schizophrenia 36 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
invasive ductal carcinoma 34 | 2,951
primitive neuroectodermal tumor 34 | 3,035
group 4 medulloblastoma 30 | 1,855
pituitary cancer 30 | 1,972
Alzheimer's disease 28 | 658
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,989
Bipolar Disorder 27 | 666
colon cancer 27 | 1,478
pancreatic cancer 27 | 2,398
interstitial cystitis 26 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
non-small cell lung cancer 25 | 2,890
Neurodegenerative disease 24 | 414
ulcerative colitis 23 | 1,819
Intellectual disability 22 | 1,016
lung adenocarcinoma 22 | 2,716
tuberculosis 21 | 2,010
Down syndrome 18 | 499
breast carcinoma 18 | 1,638
cystic fibrosis 18 | 1,696
primary pancreatic ductal adenocarcinoma 18 | 1,109
Liver cancer 17 | 604
adrenocortical carcinoma 17 | 1,428
ductal carcinoma in situ 16 | 1,745
Depressive disorder 15 | 409
Rheumatoid arthritis 15 | 1,191
cutaneous lupus erythematosus 15 | 1,057
diabetes mellitus 15 | 1,728
Amyotrophic lateral sclerosis 14 | 451
Autistic Disorder 14 | 364
Autosomal recessive predisposition 14 | 1,442
Epilepsy 14 | 792
astrocytoma 14 | 1,146
juvenile dermatomyositis 12 | 1,187
nasopharyngeal carcinoma 12 | 1,058
spina bifida 12 | 1,074
Cognitive delay 11 | 608
Dementia 11 | 175
Global developmental delay 11 | 608
Mental Depression 11 | 333
Mental and motor retardation 11 | 608
Nerve Degeneration 11 | 121
Seizures 11 | 596
Vascular disease 11 | 319
dermatomyositis 11 | 966
interstitial lung disease 11 | 298
Muscle hypotonia 10 | 571
Parkinson's disease 10 | 392
Toxic encephalopathy 10 | 141
medulloblastoma 10 | 720
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Atopic dermatitis 9 | 952
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Mood Disorders 9 | 184
Neuropathy 9 | 261
Poor school performance 9 | 645
mucosa-associated lymphoid tissue lymphoma 9 | 484
pediatric high grade glioma 9 | 1,064
Alcoholic Intoxication, Chronic 8 | 289
Cerebrovascular disease 8 | 238
Cryptorchidism 8 | 296
Liver Cirrhosis, Experimental 8 | 769
Major Depressive Disorder 8 | 301
Melanoma 8 | 711
Short stature 8 | 531
Skin cancer 8 | 469
acute quadriplegic myopathy 8 | 1,158
aldosterone-producing adenoma 8 | 665
gastric carcinoma 8 | 807
posterior fossa group B ependymoma 8 | 416
Endometriosis 7 | 540
Small head 7 | 374
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
chronic rhinosinusitis 7 | 512

Tissue

Endocrine System 138 | 18,159
Female tissues 136 | 17,400
Male tissues 136 | 17,142
Digestive Tract 134 | 17,369
Liver and Pancreas 134 | 16,750
Skin and soft tissues 134 | 17,230
Blood and immune system 133 | 16,909
Nervous System 133 | 16,725
Respiratory system 133 | 16,393
Urinary Tract 132 | 16,678
Cardiovascular System 121 | 15,192

Target Family

Non-IDG 108 | 12,091
Enzyme 17 | 4,145
Kinase 9 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344

Compartment GO Term

Growth cone 140 | 140
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Putative segment polarity protein dishevelled homolog DVL1P1 DVL1P1 Tdark Non-IDG -2.11561 188.4 0
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.89275 74.1 161
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258