Development Level

Tbio 28 | 11,445
Tdark 6 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 4 | 278
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal cranium morphology 2 | 36
decreased bone mineral content 2 | 151
increased circulating alkaline... 2 | 122
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal tail morphology 1 | 25
convulsive seizures 1 | 13
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased pulmonary respirator... 1 | 5
decreased spleen weight 1 | 10
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
short tibia 1 | 97
spina bifida 1 | 2
syndactyly 1 | 23

Disease

Carcinoma 26 | 11,493
ovarian cancer 24 | 8,520
osteosarcoma 21 | 7,950
glioblastoma 10 | 5,792
medulloblastoma, large-cell 10 | 6,241
Congenital disorder of glycosylation 9 | 54
group 4 medulloblastoma 8 | 1,855
psoriasis 8 | 6,694
Autosomal recessive predisposition 7 | 1,442
lung cancer 7 | 4,740
diabetes mellitus 6 | 1,728
ependymoma 6 | 4,679
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Astrocytoma, Pilocytic 4 | 3,081
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Kidney cancer 4 | 2,613
Mental and motor retardation 4 | 608
Multiple myeloma 4 | 1,332
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primitive neuroectodermal tumor 4 | 3,035
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Cerebellar Ataxia 3 | 304
Epilepsy 3 | 792
Liver Dysfunction 3 | 99
Muscle hypotonia 3 | 571
Schizophrenia 3 | 1,160
group 3 medulloblastoma 3 | 4,104
hepatocellular carcinoma 3 | 547
invasive ductal carcinoma 3 | 2,951
non primary Sjogren syndrome sicca 3 | 891
oligodendroglioma 3 | 2,850
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Atrophy of cerebellum 2 | 103
Cerebellar degeneration 2 | 103
Cerebral atrophy 2 | 178
Congenital dyserythropoietic anemia 2 | 18
Contracture 2 | 96
Contracture of joint 2 | 93
Curvature of spine 2 | 282
Cutis Laxa 2 | 39
Degenerative brain disorder 2 | 100
Dull intelligence 2 | 645
Elevated hepatic transaminases 2 | 81
Enterovirus Infections 2 | 6
Esotropia 2 | 31
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Galactosemia 2 | 19
Generalized osteopenia 2 | 99
Heart disease 2 | 306
Hepatic enzyme increased 2 | 81
Hypomyelinating leukodystrophy 6 2 | 26
Hypoplasia of corpus callosum 2 | 90
Hypothyroidism 2 | 122
Infratentorial atrophy 2 | 103
Irritation - emotion 2 | 68
Isoelectric focusing of serum transferrin consistent with CDG type I 2 | 10
Legionnaires' disease 2 | 20
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Oculocerebrorenal syndrome 2 | 29
Osteopenia 2 | 99
Poor school performance 2 | 645
Progressive disorder 2 | 142
Progressive microcephaly 2 | 32
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Small head 2 | 374
Spastic Quadriplegia 2 | 42
Stomatitis 2 | 21
Subclinical abnormal liver function tests 2 | 81
Supratentorial atrophy 2 | 94
Transaminases increased 2 | 81
Waldenstrons macroglobulinemia 2 | 765
Warburg micro syndrome 2 | 18
astrocytic glioma 2 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
gastric cancer 2 | 459
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
subependymal giant cell astrocytoma 2 | 2,287
Hyperglycemia 1 | 137
Steatohepatitis 1 | 44

Tissue

Blood and immune system 35 | 16,909
Female tissues 35 | 17,400
Skin and soft tissues 35 | 17,230
Cardiovascular System 34 | 15,192
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Respiratory system 34 | 16,393
Urinary Tract 34 | 16,678

Target Family

Non-IDG 29 | 12,091
Enzyme 7 | 4,145

Compartment GO Term

Golgi transport complex 36 | 36
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170
Conserved oligomeric Golgi complex subunit 1 COG1 Tbio Non-IDG -1.68066 45.6 91
Golgin subfamily A member 3 GOLGA3 Tbio Non-IDG -1.33499 21.1 140
Protein ERGIC-53 LMAN1 Tbio Non-IDG -2.44907 270.7 118
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Golgi SNAP receptor complex member 1 GOSR1 Tbio Non-IDG -1.32565 21.7 128
Vesicle-trafficking protein SEC22a SEC22A Tdark Non-IDG 0.33 0.44 19
Transmembrane protein 132A TMEM132A Tdark Non-IDG -0.23045 2.47 54
Phosphomannomutase 2 PMM2 Tchem Enzyme -2.12990 128.2 153
Vesicle-fusing ATPase NSF Tbio Enzyme -2.93271 688.8 206