Development Level

Tbio 107 | 11,651
Tdark 15 | 6,593
Tchem 9 | 1,388

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to t... 7 | 278
preweaning lethality, incomple... 6 | 499
decreased body weight 4 | 161
edema 4 | 59
abnormal bone structure 3 | 187
abnormal craniofacial morpholo... 3 | 33
abnormal embryo size 3 | 220
abnormal eye morphology 3 | 68
abnormal limb morphology 3 | 13
abnormal tail movements 3 | 12
anophthalmia 3 | 33
decreased circulating HDL chol... 3 | 68
decreased circulating calcium ... 3 | 36
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
polydactyly 3 | 7
abnormal body wall morphology 2 | 9
abnormal facial morphology 2 | 17
abnormal gait 2 | 69
abnormal limb bud morphology 2 | 17
abnormal sleep behavior 2 | 70
cleft palate 2 | 8
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
facial cleft 2 | 3
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal forebrain morphology 1 | 10
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal response to new envir... 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
decreased B cell number 1 | 5
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased pulmonary respirator... 1 | 5
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
increased CD8-positive, alpha-... 1 | 1
increased T cell number 1 | 6
increased circulating amylase ... 1 | 25
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased circulating magnesiu... 1 | 10
increased circulating thyroxin... 1 | 7
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
short tibia 1 | 97
thick skin 1 | 4
thrombocytopenia 1 | 56
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 83 | 11,493
ovarian cancer 83 | 8,520
osteosarcoma 65 | 7,950
glioblastoma 53 | 5,792
psoriasis 53 | 6,694
medulloblastoma, large-cell 52 | 6,241
atypical teratoid / rhabdoid tumor 41 | 5,112
ependymoma 37 | 4,679
lung cancer 36 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
Astrocytoma, Pilocytic 25 | 3,081
Breast cancer 25 | 3,578
adult high grade glioma 24 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
invasive ductal carcinoma 22 | 2,951
lung adenocarcinoma 22 | 2,716
group 4 medulloblastoma 21 | 1,855
pancreatic cancer 21 | 2,398
group 3 medulloblastoma 20 | 4,104
malignant mesothelioma 20 | 3,232
oligodendroglioma 20 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Multiple myeloma 18 | 1,332
astrocytic glioma 18 | 2,597
cystic fibrosis 18 | 1,696
interstitial cystitis 17 | 2,312
lung carcinoma 17 | 2,843
tuberculosis 17 | 2,010
Kidney cancer 16 | 2,613
Pick disease 15 | 1,894
astrocytoma 15 | 1,146
pediatric high grade glioma 15 | 1,064
primitive neuroectodermal tumor 15 | 3,035
non-small cell lung cancer 13 | 2,890
pituitary cancer 13 | 1,972
spina bifida 12 | 1,074
Cancer 11 | 2,499
acute quadriplegic myopathy 10 | 1,158
breast carcinoma 10 | 1,638
dermatomyositis 10 | 966
juvenile dermatomyositis 10 | 1,187
non primary Sjogren syndrome sicca 10 | 891
primary pancreatic ductal adenocarcinoma 10 | 1,109
subependymal giant cell astrocytoma 10 | 2,287
ulcerative colitis 10 | 1,819
Waldenstrons macroglobulinemia 9 | 765
acute myeloid leukemia 9 | 783
diabetes mellitus 9 | 1,728
Amyotrophic lateral sclerosis 8 | 451
Autosomal recessive predisposition 8 | 1,442
active Crohn's disease 8 | 922
active ulcerative colitis 8 | 764
ductal carcinoma in situ 8 | 1,745
Alzheimer's disease 7 | 658
atypical teratoid/rhabdoid tumor 7 | 357
esophageal adenocarcinoma 7 | 737
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Intellectual disability 6 | 1,016
Mental and motor retardation 6 | 608
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
colon cancer 6 | 1,478
gastric carcinoma 6 | 807
hereditary spastic paraplegia 6 | 318
primary Sjogren syndrome 6 | 735
sonic hedgehog group medulloblastoma 6 | 467
Chronic Lymphocytic Leukemia 5 | 262
Duchenne muscular dystrophy 5 | 601
Liver Cirrhosis, Experimental 5 | 769
Neurodegenerative disease 5 | 414
Polycystic ovary syndrome 5 | 360
Schizophrenia 5 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
cutaneous lupus erythematosus 5 | 1,057
medulloblastoma 5 | 720
Bipolar Disorder 4 | 666
Cardiovascular system disease 4 | 246
Down syndrome 4 | 499
Dull intelligence 4 | 645
Epilepsy 4 | 792
Heart disease 4 | 306
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Obesity 4 | 678
Oculocerebrorenal syndrome 4 | 29
Poor school performance 4 | 645
Short stature 4 | 531
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
fibroadenoma 4 | 559
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
progressive supranuclear palsy 4 | 676
tuberculosis and treatment for 6 months 4 | 409
nephrosclerosis 3 | 333
periodontitis 3 | 293

Tissue

Endocrine System 127 | 18,159
Female tissues 126 | 17,400
Nervous System 126 | 16,725
Digestive Tract 125 | 17,369
Male tissues 125 | 17,142
Liver and Pancreas 124 | 16,750
Urinary Tract 124 | 16,678
Blood and immune system 123 | 16,909
Respiratory system 123 | 16,393
Skin and soft tissues 123 | 17,230
Cardiovascular System 120 | 15,192

Target Family

Enzyme 69 | 4,145
Non-IDG 58 | 12,091
Ion Channel 2 | 344
Kinase 2 | 634

Compartment GO Term

Golgi stack 131 | 131
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 Tbio Enzyme -2.80894 644.1 124
Beta-1,3-galactosyltransferase 6 B3GALT6 Tbio Enzyme -1.00350 10.1 132
Alpha-(1,3)-fucosyltransferase 7 FUT7 Tchem Enzyme -1.85814 81.0 121
Serine/threonine-protein kinase VRK1 VRK1 Tbio Kinase -2.05267 119.8 168
A-kinase anchor protein 9 AKAP9 Tbio Enzyme -2.22554 169.7 142
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.88151 7.21 111
Soluble calcium-activated nucleotidase 1 CANT1 Tbio Enzyme -1.42839 27.2 210