Development Level

Tbio 584 | 11,651
Tdark 81 | 6,593
Tchem 52 | 1,388
Tclin 7 | 612

Collection

RFA-RM-18-021 7 | 328
Kinase: IDG Consortium (Target... 4 | 125
Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

preweaning lethality, complete... 40 | 979
preweaning lethality, incomple... 27 | 499
embryonic lethality prior to t... 20 | 278
decreased total body fat amoun... 15 | 207
embryonic lethality prior to o... 15 | 239
abnormal bone structure 14 | 187
increased lean body mass 12 | 172
increased bone mineral content 11 | 108
abnormal embryo size 10 | 220
increased startle reflex 10 | 112
abnormal behavior 9 | 298
abnormal kidney morphology 9 | 65
decreased bone mineral content 9 | 151
decreased vertical activity 9 | 208
enlarged heart 9 | 210
hypoactivity 9 | 132
increased mean corpuscular hem... 9 | 96
abnormal sleep behavior 8 | 70
increased heart weight 8 | 62
increased mean corpuscular vol... 8 | 92
abnormal eye morphology 7 | 68
abnormal seminal vesicle morph... 7 | 114
cataract 7 | 92
decreased body weight 7 | 161
decreased circulating serum al... 7 | 82
abnormal behavioral response t... 6 | 66
abnormal heart morphology 6 | 162
abnormal lens morphology 6 | 81
abnormal retina morphology 6 | 71
decreased body length 6 | 101
decreased circulating choleste... 6 | 93
decreased grip strength 6 | 116
increased bone mineral density 6 | 72
decreased bone mineral density 5 | 126
decreased circulating LDL chol... 5 | 38
decreased circulating insulin ... 5 | 76
embryonic growth retardation 5 | 106
enlarged kidney 5 | 14
hyperactivity 5 | 148
increased circulating alkaline... 5 | 122
male infertility 5 | 123
abnormal neural tube closure 4 | 46
abnormal spleen morphology 4 | 55
decreased circulating HDL chol... 4 | 68
decreased circulating alanine ... 4 | 47
decreased circulating glucose ... 4 | 126
decreased fasted circulating g... 4 | 65
decreased lean body mass 4 | 135
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular vol... 4 | 79
decreased prepulse inhibition 4 | 82
edema 4 | 59
increased circulating chloride... 4 | 41
increased grip strength 4 | 41
increased monocyte cell number 4 | 63
increased total body fat amoun... 4 | 134
abnormal coat appearance 3 | 31
abnormal cranium morphology 3 | 36
abnormal epididymis morphology 3 | 42
abnormal gait 3 | 69
abnormal limb morphology 3 | 13
abnormal skin morphology 3 | 50
abnormal testis morphology 3 | 43
abnormal vibrissa morphology 3 | 25
cardiovascular system phenotyp... 3 | 36
decreased circulating creatini... 3 | 39
decreased circulating triglyce... 3 | 79
decreased hemoglobin content 3 | 68
decreased lactate dehydrogenas... 3 | 16
decreased leukocyte cell numbe... 3 | 73
decreased mean corpuscular hem... 3 | 50
enlarged epididymis 3 | 31
increased circulating serum al... 3 | 22
limb grasping 3 | 41
prenatal lethality 3 | 28
short tibia 3 | 97
small testis 3 | 58
thrombocytosis 3 | 27
abnormal craniofacial morpholo... 2 | 33
abnormal limb bud morphology 2 | 17
abnormal lung morphology 2 | 26
abnormal tail movements 2 | 12
anophthalmia 2 | 33
decreased caudal vertebrae num... 2 | 53
decreased circulating calcium ... 2 | 36
decreased circulating potassiu... 2 | 20
decreased hematocrit 2 | 46
enlarged spleen 2 | 41
hydrometra 2 | 53
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
increased body length 2 | 32
increased circulating triglyce... 2 | 42
increased exploration in new e... 2 | 8
increased fasted circulating g... 2 | 76
increased or absent threshold ... 2 | 101
pale yolk sac 2 | 25
pallor 2 | 34
small superior vagus ganglion 2 | 74
tremors 2 | 39

Disease

Carcinoma 459 | 11,493
ovarian cancer 387 | 8,520
osteosarcoma 322 | 7,950
psoriasis 288 | 6,694
glioblastoma 270 | 5,792
medulloblastoma, large-cell 256 | 6,241
atypical teratoid / rhabdoid tumor 222 | 5,112
ependymoma 200 | 4,679
lung cancer 184 | 4,740
Astrocytoma, Pilocytic 159 | 3,081
Cancer 153 | 2,499
Breast cancer 152 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 150 | 2,955
adult high grade glioma 148 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 147 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 137 | 3,291
lung carcinoma 127 | 2,843
invasive ductal carcinoma 126 | 2,951
malignant mesothelioma 124 | 3,232
diabetes mellitus 123 | 1,728
group 3 medulloblastoma 123 | 4,104
lung adenocarcinoma 112 | 2,716
pancreatic cancer 112 | 2,398
oligodendroglioma 111 | 2,850
astrocytic glioma 109 | 2,597
group 4 medulloblastoma 108 | 1,855
tuberculosis 103 | 2,010
primitive neuroectodermal tumor 101 | 3,035
non-small cell lung cancer 96 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 96 | 1,962
pituitary cancer 95 | 1,972
Rheumatoid arthritis 94 | 1,191
Kidney cancer 93 | 2,613
interstitial cystitis 87 | 2,312
subependymal giant cell astrocytoma 86 | 2,287
Pick disease 82 | 1,894
dermatomyositis 81 | 966
Ankylosing spondylitis 72 | 140
Multiple myeloma 72 | 1,332
Behcet's disease 70 | 89
Hypersensitivity reaction type II disease 69 | 253
ductal carcinoma in situ 68 | 1,745
Autosomal recessive predisposition 66 | 1,442
Arthritis 65 | 290
breast carcinoma 65 | 1,638
juvenile dermatomyositis 65 | 1,187
Juvenile rheumatoid arthritis 61 | 111
cystic fibrosis 61 | 1,696
Acquired immunodeficiency syndrome 60 | 197
Uveitis 59 | 103
astrocytoma 59 | 1,146
active Crohn's disease 57 | 922
pediatric high grade glioma 57 | 1,064
ulcerative colitis 57 | 1,819
Herpes zoster 56 | 68
Human immunodeficiency virus infectious disease 54 | 138
Psoriatic arthritis 54 | 86
Intellectual disability 53 | 1,016
primary pancreatic ductal adenocarcinoma 53 | 1,109
Stevens-Johnson syndrome 52 | 92
adrenocortical carcinoma 52 | 1,428
acute quadriplegic myopathy 48 | 1,158
Multiple Sclerosis 47 | 540
spina bifida 47 | 1,074
colon cancer 46 | 1,478
Schizophrenia 45 | 1,160
active ulcerative colitis 45 | 764
Epilepsy 43 | 792
non primary Sjogren syndrome sicca 43 | 891
Kidney disease 39 | 430
Liver disease 38 | 237
Dermatitis 37 | 157
aldosterone-producing adenoma 37 | 665
cutaneous lupus erythematosus 37 | 1,057
Alzheimer's disease 36 | 658
Behcet's syndrome 36 | 50
drug-induced hepatitis 36 | 44
Anemia 35 | 365
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Seizures 35 | 596
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
pancreatic carcinoma 35 | 562
nasopharyngeal carcinoma 34 | 1,058
primary Sjogren syndrome 34 | 735
Cognitive delay 33 | 608
Dull intelligence 33 | 645
Global developmental delay 33 | 608
Low intelligence 33 | 645
Mental Retardation 33 | 645
Mental and motor retardation 33 | 608
Mental deficiency 33 | 645
Poor school performance 33 | 645
Down syndrome 32 | 499
esophageal adenocarcinoma 31 | 737
gastric carcinoma 31 | 807
Muscle hypotonia 30 | 571

Tissue

Endocrine System 637 | 18,159
Digestive Tract 631 | 17,369
Female tissues 630 | 17,400
Nervous System 627 | 16,725
Skin and soft tissues 624 | 17,230
Liver and Pancreas 623 | 16,750
Male tissues 623 | 17,142
Blood and immune system 621 | 16,909
Urinary Tract 620 | 16,678
Respiratory system 615 | 16,393
Cardiovascular System 588 | 15,192

Target Family

Non-IDG 380 | 12,091
Enzyme 285 | 4,145
Transporter 25 | 473
Kinase 11 | 634
Transcription Factor 10 | 1,400
Ion Channel 7 | 344
GPCR 6 | 408

Compartment GO Term

Golgi membrane 724 | 724
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Beta-1,3-galactosyltransferase 1 B3GALT1 Tbio Enzyme -0.68296 3.85 66
Sphingomyelin phosphodiesterase 4 SMPD4 Tbio Enzyme -0.89678 7.05 66
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0