Development Level

Tbio 537 | 10,625
Tdark 94 | 7,003
Tchem 72 | 1,890
Tclin 7 | 602

Collection

Eligible Kinase Proteins 4 | 134
Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 28 | 633
embryonic lethality prior to t... 13 | 187
decreased total body fat amoun... 12 | 186
abnormal bone structure 11 | 131
decreased bone mineral content 11 | 157
decreased lean body mass 10 | 195
increased mean corpuscular hem... 9 | 93
preweaning lethality, incomple... 9 | 260
decreased circulating HDL chol... 8 | 77
decreased circulating choleste... 8 | 85
increased mean corpuscular vol... 8 | 91
abnormal behavior 7 | 226
decreased body length 7 | 108
decreased body weight 7 | 174
decreased bone mineral density 7 | 126
decreased circulating alanine ... 7 | 53
decreased circulating triglyce... 7 | 83
decreased grip strength 7 | 123
increased heart weight 7 | 37
abnormal bone mineralization 6 | 55
abnormal lens morphology 6 | 73
abnormal retina morphology 6 | 100
decreased circulating LDL chol... 6 | 37
embryonic lethality prior to o... 6 | 148
hypoactivity 6 | 89
increased bone mineral content 6 | 92
increased lean body mass 6 | 107
abnormal sleep behavior 5 | 63
decreased circulating serum al... 5 | 79
decreased fasted circulating g... 5 | 49
decreased prepulse inhibition 5 | 52
enlarged heart 5 | 111
male infertility 5 | 62
abnormal QRS complex 4 | 25
abnormal retinal pigmentation 4 | 61
cardiovascular system phenotyp... 4 | 35
decreased circulating glucose ... 4 | 121
decreased circulating insulin ... 4 | 75
increased circulating alkaline... 4 | 119
increased grip strength 4 | 83
increased or absent threshold ... 4 | 128
abnormal eye morphology 3 | 38
abnormal kidney morphology 3 | 30
abnormal testis morphology 3 | 30
cataract 3 | 26
decreased CD8-positive, alpha-... 3 | 26
decreased NK T cell number 3 | 28
decreased T cell number 3 | 31
decreased heart weight 3 | 44
decreased hemoglobin content 3 | 53
decreased lactate dehydrogenas... 3 | 14
decreased mean corpuscular hem... 3 | 34
decreased vertical activity 3 | 22
hydrops fetalis 3 | 22
hyperactivity 3 | 108
increased blood urea nitrogen ... 3 | 44
increased bone mineral density 3 | 52
increased circulating chloride... 3 | 43
straub tail 3 | 26
abnormal behavioral response t... 2 | 52
abnormal coat appearance 2 | 25
abnormal cranium morphology 2 | 32
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal spleen morphology 2 | 36
abnormal tail movements 2 | 12
abnormal vibrissa morphology 2 | 17
decreased caudal vertebrae num... 2 | 49
decreased circulating calcium ... 2 | 33
decreased circulating creatini... 2 | 31
decreased circulating free fat... 2 | 39
decreased circulating glycerol... 2 | 19
decreased circulating potassiu... 2 | 17
decreased eosinophil cell numb... 2 | 41
decreased hematocrit 2 | 25
decreased mean corpuscular vol... 2 | 50
decreased rib number 2 | 59
enlarged spleen 2 | 26
impaired glucose tolerance 2 | 52
increased CD5-positive Ly6C-po... 2 | 4
increased body weight 2 | 42
increased circulating glycerol... 2 | 11
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 25
increased prepulse inhibition 2 | 21
increased sacral vertebrae num... 2 | 62
limb grasping 2 | 35
short tibia 2 | 82
small testis 2 | 37
thrombocytopenia 2 | 46
thrombocytosis 2 | 23
tremors 2 | 34

Disease

ovarian cancer 376 | 8,492
osteosarcoma 321 | 7,933
psoriasis 284 | 6,685
glioblastoma 257 | 5,572
medulloblastoma, large-cell 250 | 6,234
atypical teratoid / rhabdoid tumor 199 | 4,369
lung cancer 170 | 4,473
pilocytic astrocytoma 158 | 3,086
Cancer 151 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 147 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 142 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 135 | 3,289
Breast cancer 133 | 3,099
invasive ductal carcinoma 129 | 2,950
lung carcinoma 126 | 2,844
diabetes mellitus 122 | 1,663
malignant mesothelioma 115 | 3,163
lung adenocarcinoma 114 | 2,714
pancreatic cancer 113 | 2,300
oligodendroglioma 107 | 2,849
adult high grade glioma 102 | 2,148
ependymoma 101 | 2,514
pediatric high grade glioma 100 | 2,712
group 4 medulloblastoma 99 | 1,875
primitive neuroectodermal tumor 99 | 3,031
pituitary cancer 97 | 1,972
Rheumatoid Arthritis 96 | 1,171
non-small cell lung cancer 93 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 88 | 1,795
astrocytic glioma 87 | 2,241
interstitial cystitis 87 | 2,299
subependymal giant cell astrocytoma 85 | 2,287
dermatomyositis 82 | 967
Pick disease 77 | 1,893
astrocytoma 77 | 1,493
Carcinoma 74 | 2,147
posterior fossa group A ependymoma 73 | 1,511
Ankylosing spondylitis 72 | 138
Multiple myeloma 70 | 1,328
ductal carcinoma in situ 70 | 1,745
ulcerative colitis 69 | 2,087
Hypersensitivity reaction type II disease 68 | 235
group 3 medulloblastoma 65 | 2,254
tuberculosis 65 | 1,563
breast carcinoma 64 | 1,614
juvenile dermatomyositis 63 | 1,189
Arthritis 62 | 248
cystic fibrosis 62 | 1,670
Juvenile rheumatoid arthritis 61 | 105
Uveitis 59 | 103
Acquired immunodeficiency syndrome 58 | 164
active Crohn's disease 58 | 918
primary pancreatic ductal adenocarcinoma 58 | 1,271
Behcet's disease 56 | 74
medulloblastoma 56 | 1,524
posterior fossa group B ependymoma 56 | 1,530
Human immunodeficiency virus infectious disease 52 | 129
Psoriatic arthritis 52 | 85
Stevens-Johnson syndrome 52 | 91
adrenocortical carcinoma 50 | 1,427
Multiple Sclerosis 48 | 498
acute quadriplegic myopathy 48 | 1,157
spina bifida 45 | 1,064
colon cancer 44 | 1,475
sonic hedgehog group medulloblastoma 44 | 1,482
primary Sjogren syndrome 40 | 789
Nephritis 38 | 63
non primary Sjogren syndrome sicca 38 | 840
Liver disease 37 | 219
cutaneous lupus erythematosus 37 | 1,056
tuberculosis and treatment for 6 months 37 | 686
Behcet's syndrome 36 | 50
Dermatitis 36 | 141
Kidney disease 36 | 397
aldosterone-producing adenoma 36 | 664
atypical teratoid/rhabdoid tumor 36 | 1,095
drug-induced hepatitis 36 | 44
pancreatic carcinoma 36 | 567
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 72
Takayasu's arteritis 35 | 54
Alzheimer's disease 34 | 644
gastric carcinoma 34 | 832
nasopharyngeal carcinoma 33 | 1,056
active ulcerative colitis 32 | 477
Anemia 31 | 252
Down syndrome 31 | 548
Intellectual disability 31 | 573
esophageal adenocarcinoma 30 | 737
hepatocellular carcinoma 30 | 550
acute myeloid leukemia 28 | 785
Atopic dermatitis 27 | 944
Hepatitis B 27 | 103
progressive supranuclear palsy 26 | 674
Duchenne muscular dystrophy 25 | 602
Leprosy 24 | 77
Neurodegenerative disease 24 | 383
Waldenstrons macroglobulinemia 24 | 765

Tissue

Nervous System 639 | 18,561
Digestive Tract 636 | 18,473
Endocrine System 636 | 18,512
Female tissues 635 | 18,647
Cardiovascular System 634 | 17,958
Liver and Pancreas 634 | 18,136
Blood and immune system 633 | 17,995
Male tissues 633 | 17,969
Urinary Tract 633 | 18,444
Respiratory system 627 | 17,484
Skin and soft tissues 623 | 18,115

Target Family

Non-IDG 371 | 11,969
Enzyme 283 | 4,146
Transporter 24 | 473
Kinase 11 | 634
Transcription Factor 8 | 1,400
Ion Channel 7 | 341
GPCR 6 | 408

Compartment GO Term

Golgi membrane 710 | 710
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.07995 1275.9 729
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.16287 147.6 149
Protein dopey-2 DOPEY2 Tbio Non-IDG -0.67912 6.04 14
Soluble calcium-activated nucleotidase 1 CANT1 Tbio Enzyme -1.42022 25.3 175
NEDD4 family-interacting protein 2 NDFIP2 Tbio Non-IDG -0.60179 4.85 31
Short coiled-coil protein SCOC Tbio Non-IDG -0.94741 29.3 35
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.85200 7.21 86
Protein YIF1B YIF1B Tbio Non-IDG -0.80844 5.59 61
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.46179 31.8 115
Sugar transporter SWEET1 SLC50A1 Tdark Transporter -2.21066 159.5 50