Development Level

Tbio 560 | 11,178
Tdark 81 | 6,569
Tchem 67 | 1,885
Tclin 7 | 612

Collection

Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 39 | 979
preweaning lethality, incomple... 26 | 499
embryonic lethality prior to t... 19 | 278
decreased total body fat amoun... 15 | 207
embryonic lethality prior to o... 15 | 239
abnormal bone structure 14 | 187
increased lean body mass 12 | 172
increased bone mineral content 11 | 108
abnormal embryo size 10 | 220
increased startle reflex 10 | 112
abnormal behavior 9 | 298
abnormal kidney morphology 9 | 65
decreased bone mineral content 9 | 151
decreased vertical activity 9 | 208
enlarged heart 9 | 210
hypoactivity 9 | 132
increased mean corpuscular hem... 9 | 96
abnormal sleep behavior 8 | 70
increased heart weight 8 | 62
increased mean corpuscular vol... 8 | 92
abnormal eye morphology 7 | 68
abnormal seminal vesicle morph... 7 | 114
cataract 7 | 92
decreased body weight 7 | 161
decreased circulating serum al... 7 | 82
abnormal behavioral response t... 6 | 66
abnormal heart morphology 6 | 162
abnormal lens morphology 6 | 81
abnormal retina morphology 6 | 71
decreased body length 6 | 101
decreased circulating choleste... 6 | 93
decreased grip strength 6 | 116
increased bone mineral density 6 | 72
decreased bone mineral density 5 | 126
decreased circulating LDL chol... 5 | 38
decreased circulating insulin ... 5 | 76
embryonic growth retardation 5 | 106
enlarged kidney 5 | 14
hyperactivity 5 | 148
increased circulating alkaline... 5 | 122
male infertility 5 | 123
abnormal neural tube closure 4 | 46
abnormal spleen morphology 4 | 55
decreased circulating HDL chol... 4 | 68
decreased circulating alanine ... 4 | 47
decreased circulating glucose ... 4 | 126
decreased fasted circulating g... 4 | 65
decreased lean body mass 4 | 135
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular vol... 4 | 79
decreased prepulse inhibition 4 | 82
edema 4 | 59
increased circulating chloride... 4 | 41
increased grip strength 4 | 41
increased monocyte cell number 4 | 63
increased total body fat amoun... 4 | 134
abnormal coat appearance 3 | 31
abnormal cranium morphology 3 | 36
abnormal epididymis morphology 3 | 42
abnormal gait 3 | 69
abnormal limb morphology 3 | 13
abnormal skin morphology 3 | 50
abnormal testis morphology 3 | 43
cardiovascular system phenotyp... 3 | 36
decreased circulating creatini... 3 | 39
decreased circulating triglyce... 3 | 79
decreased hemoglobin content 3 | 68
decreased lactate dehydrogenas... 3 | 16
decreased leukocyte cell numbe... 3 | 73
decreased mean corpuscular hem... 3 | 50
enlarged epididymis 3 | 31
increased circulating serum al... 3 | 22
limb grasping 3 | 41
prenatal lethality 3 | 28
short tibia 3 | 97
small testis 3 | 58
thrombocytosis 3 | 27
abnormal craniofacial morpholo... 2 | 33
abnormal limb bud morphology 2 | 17
abnormal lung morphology 2 | 26
abnormal tail movements 2 | 12
abnormal vibrissa morphology 2 | 25
anophthalmia 2 | 33
decreased caudal vertebrae num... 2 | 53
decreased circulating aspartat... 2 | 34
decreased circulating calcium ... 2 | 36
decreased circulating potassiu... 2 | 20
decreased hematocrit 2 | 46
enlarged spleen 2 | 41
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
increased body length 2 | 32
increased circulating triglyce... 2 | 42
increased exploration in new e... 2 | 8
increased fasted circulating g... 2 | 76
increased or absent threshold ... 2 | 101
pale yolk sac 2 | 25
pallor 2 | 34
small superior vagus ganglion 2 | 74
tremors 2 | 39

Disease

Carcinoma 452 | 11,192
ovarian cancer 380 | 8,297
osteosarcoma 315 | 7,766
psoriasis 282 | 6,514
glioblastoma 266 | 5,635
medulloblastoma, large-cell 252 | 6,086
atypical teratoid / rhabdoid tumor 217 | 4,971
ependymoma 195 | 4,559
lung cancer 182 | 4,607
Astrocytoma, Pilocytic 156 | 3,006
Breast cancer 150 | 3,469
intraductal papillary-mucinous adenoma (IPMA) 150 | 2,872
Cancer 149 | 2,388
intraductal papillary-mucinous carcinoma (IPMC) 147 | 2,902
adult high grade glioma 145 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 137 | 3,204
invasive ductal carcinoma 125 | 2,867
diabetes mellitus 123 | 1,683
lung carcinoma 122 | 2,755
malignant mesothelioma 122 | 3,135
group 3 medulloblastoma 120 | 4,002
lung adenocarcinoma 112 | 2,627
pancreatic cancer 112 | 2,322
oligodendroglioma 108 | 2,768
astrocytic glioma 106 | 2,530
group 4 medulloblastoma 105 | 1,806
tuberculosis 103 | 1,963
primitive neuroectodermal tumor 100 | 2,957
non-small cell lung cancer 95 | 2,799
pituitary cancer 95 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 93 | 1,911
Kidney cancer 92 | 2,548
Rheumatoid arthritis 92 | 1,156
interstitial cystitis 85 | 2,237
subependymal giant cell astrocytoma 85 | 2,230
Pick disease 80 | 1,856
dermatomyositis 80 | 941
Ankylosing spondylitis 72 | 134
Multiple myeloma 72 | 1,296
Behcet's disease 70 | 87
Hypersensitivity reaction type II disease 69 | 245
ductal carcinoma in situ 68 | 1,686
Autosomal recessive predisposition 66 | 1,407
Arthritis 65 | 276
breast carcinoma 65 | 1,589
juvenile dermatomyositis 63 | 1,147
Juvenile rheumatoid arthritis 61 | 110
cystic fibrosis 61 | 1,629
Acquired immunodeficiency syndrome 60 | 192
Uveitis 59 | 102
astrocytoma 59 | 1,113
pediatric high grade glioma 57 | 1,035
Herpes zoster 56 | 68
active Crohn's disease 56 | 882
ulcerative colitis 56 | 1,765
Human immunodeficiency virus infectious disease 54 | 136
Psoriatic arthritis 54 | 84
primary pancreatic ductal adenocarcinoma 53 | 1,071
Stevens-Johnson syndrome 52 | 92
Intellectual disability 51 | 998
adrenocortical carcinoma 51 | 1,385
acute quadriplegic myopathy 48 | 1,133
Multiple Sclerosis 47 | 527
spina bifida 47 | 1,053
colon cancer 46 | 1,428
Schizophrenia 44 | 1,136
active ulcerative colitis 44 | 736
non primary Sjogren syndrome sicca 42 | 861
Epilepsy 41 | 775
Kidney disease 39 | 411
Liver disease 38 | 227
Dermatitis 37 | 154
aldosterone-producing adenoma 37 | 646
cutaneous lupus erythematosus 37 | 1,016
Behcet's syndrome 36 | 49
drug-induced hepatitis 36 | 44
Anemia 35 | 353
Congenital adrenal hyperplasia 35 | 71
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 75
Takayasu's arteritis 35 | 53
pancreatic carcinoma 35 | 555
Alzheimer's disease 34 | 640
Seizures 33 | 584
nasopharyngeal carcinoma 33 | 1,024
primary Sjogren syndrome 33 | 710
Cognitive delay 31 | 596
Dull intelligence 31 | 634
Global developmental delay 31 | 596
Low intelligence 31 | 634
Mental Retardation 31 | 634
Mental and motor retardation 31 | 596
Mental deficiency 31 | 634
Poor school performance 31 | 634
gastric carcinoma 31 | 781
Down syndrome 30 | 480
Muscle hypotonia 30 | 562
esophageal adenocarcinoma 30 | 696

Tissue

Endocrine System 628 | 18,159
Digestive Tract 622 | 17,369
Female tissues 621 | 17,400
Nervous System 618 | 16,725
Skin and soft tissues 615 | 17,230
Liver and Pancreas 614 | 16,750
Male tissues 614 | 17,142
Blood and immune system 612 | 16,909
Urinary Tract 611 | 16,678
Respiratory system 606 | 16,393
Cardiovascular System 580 | 15,192

Target Family

Non-IDG 377 | 12,091
Enzyme 280 | 4,145
Transporter 25 | 473
Kinase 10 | 634
Transcription Factor 10 | 1,400
Ion Channel 7 | 344
GPCR 6 | 408

Compartment GO Term

Golgi membrane 715 | 715
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

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