Development Level

Tbio 89 | 11,651
Tchem 16 | 1,388
Tdark 6 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
abnormal heart morphology 3 | 162
abnormal tail morphology 3 | 25
decreased mean corpuscular vol... 3 | 79
increased lean body mass 3 | 172
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal neural tube closure 2 | 46
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased circulating triglyce... 2 | 79
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased blood urea nitrogen ... 2 | 48
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
cataract 1 | 92
cleft palate 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased exploration in new e... 1 | 11
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating triglyce... 1 | 42
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
mydriasis 1 | 6
premature death 1 | 5
small adrenal glands 1 | 16
small heart 1 | 10
small kidney 1 | 16
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 75 | 11,493
psoriasis 61 | 6,694
ovarian cancer 53 | 8,520
osteosarcoma 42 | 7,950
Cancer 40 | 2,499
lung cancer 37 | 4,740
Breast cancer 33 | 3,578
glioblastoma 33 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
atypical teratoid / rhabdoid tumor 29 | 5,112
lung adenocarcinoma 29 | 2,716
medulloblastoma, large-cell 28 | 6,241
pancreatic cancer 27 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
invasive ductal carcinoma 25 | 2,951
lung carcinoma 25 | 2,843
cystic fibrosis 24 | 1,696
adult high grade glioma 23 | 3,801
ependymoma 23 | 4,679
non-small cell lung cancer 23 | 2,890
Astrocytoma, Pilocytic 22 | 3,081
Autosomal recessive predisposition 22 | 1,442
malignant mesothelioma 22 | 3,232
pituitary cancer 22 | 1,972
diabetes mellitus 21 | 1,728
breast carcinoma 20 | 1,638
ductal carcinoma in situ 20 | 1,745
group 3 medulloblastoma 20 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
ulcerative colitis 16 | 1,819
interstitial cystitis 15 | 2,312
oligodendroglioma 15 | 2,850
primary pancreatic ductal adenocarcinoma 14 | 1,109
Kidney cancer 13 | 2,613
Atherosclerosis 12 | 291
adrenocortical carcinoma 12 | 1,428
colon cancer 12 | 1,478
Atopic dermatitis 11 | 952
Osteoporosis 11 | 363
Rheumatoid arthritis 11 | 1,191
astrocytic glioma 11 | 2,597
astrocytoma 11 | 1,146
esophageal adenocarcinoma 11 | 737
primitive neuroectodermal tumor 11 | 3,035
sonic hedgehog group medulloblastoma 11 | 467
Liver cancer 10 | 604
Schizophrenia 10 | 1,160
active ulcerative colitis 10 | 764
fibroadenoma 10 | 559
nasopharyngeal carcinoma 10 | 1,058
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Kidney disease 9 | 430
Mental and motor retardation 9 | 608
Pick disease 9 | 1,894
cutaneous lupus erythematosus 9 | 1,057
spina bifida 9 | 1,074
Alzheimer's disease 8 | 658
Broad flat nasal bridge 8 | 236
Cerebrovascular disease 8 | 238
Duchenne muscular dystrophy 8 | 601
Epilepsy 8 | 792
Hypertension 8 | 396
Nasal bridge wide 8 | 236
Seizures 8 | 596
Short stature 8 | 531
active Crohn's disease 8 | 922
dermatomyositis 8 | 966
gastric carcinoma 8 | 807
group 4 medulloblastoma 8 | 1,855
juvenile dermatomyositis 8 | 1,187
non primary Sjogren syndrome sicca 8 | 891
subependymal giant cell astrocytoma 8 | 2,287
Asthma 7 | 385
Bipolar Disorder 7 | 666
Cleft Palate 7 | 271
Hypertensive disease 7 | 292
Intellectual disability 7 | 1,016
Large intestine cancer 7 | 126
Liver disease 7 | 237
Muscle hypotonia 7 | 571
Obesity 7 | 678
Pneumonia 7 | 174
Prostatic Neoplasms 7 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
pediatric high grade glioma 7 | 1,064
tuberculosis 7 | 2,010
Adenoma 6 | 167
Arthritis 6 | 290
Crohn's disease 6 | 321
Down syndrome 6 | 499
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Melanoma 6 | 711
Micrognathism 6 | 275
Myopathy 6 | 185
Vascular disease 6 | 319
limb girdle muscular dystrophy 2A 6 | 213
periodontitis 6 | 293

Tissue

Digestive Tract 106 | 17,369
Female tissues 103 | 17,400
Skin and soft tissues 103 | 17,230
Endocrine System 100 | 18,159
Blood and immune system 97 | 16,909
Liver and Pancreas 96 | 16,750
Urinary Tract 96 | 16,678
Male tissues 95 | 17,142
Respiratory system 93 | 16,393
Nervous System 90 | 16,725
Cardiovascular System 74 | 15,192

Target Family

Non-IDG 83 | 12,091
Enzyme 21 | 4,145
Transporter 9 | 473

Compartment GO Term

Golgi lumen 113 | 113
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Osteomodulin OMD Tbio Non-IDG -2.36749 234.5 121
Inositol monophosphatase 3 IMPAD1 Tdark Enzyme -0.78606 4.97 79
Probable UDP-sugar transporter protein SLC35A5 SLC35A5 Tdark Transporter 0.38 0.33 30
Defensin-5 DEFA5 Tbio Non-IDG -1.93853 88.3 171
Defensin-6 DEFA6 Tbio Non-IDG -1.25739 19.3 70
Nucleobindin-1 NUCB1 Tbio Non-IDG -2.75064 547.0 152
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Podocalyxin-like protein 2 PODXL2 Tbio Non-IDG -0.62337 4.07 162