Development Level

Tbio 50 | 10,625
Tdark 13 | 7,003
Tchem 8 | 1,890

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

embryonic lethality prior to t... 4 | 187
preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
abnormal lens morphology 2 | 73
increased mean corpuscular hem... 2 | 93
abnormal eye morphology 1 | 38
abnormal heart left ventricle ... 1 | 20
abnormal retinal vasculature m... 1 | 15
abnormal skin condition 1 | 6
abnormal tail movements 1 | 12
decreased NK T cell number 1 | 28
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating potassiu... 1 | 17
decreased eosinophil cell numb... 1 | 41
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
embryonic lethality prior to o... 1 | 148
hydrops fetalis 1 | 22
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
increased CD8-positive, alpha-... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased fasted circulating g... 1 | 68
increased prepulse inhibition 1 | 21
male infertility 1 | 62
straub tail 1 | 26
thick ventricular wall 1 | 7

Disease

ovarian cancer 45 | 8,492
osteosarcoma 30 | 7,933
glioblastoma 29 | 5,572
psoriasis 28 | 6,685
medulloblastoma, large-cell 24 | 6,234
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
lung cancer 17 | 4,473
atypical teratoid / rhabdoid tumor 15 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
lung adenocarcinoma 14 | 2,714
pancreatic cancer 14 | 2,300
group 4 medulloblastoma 13 | 1,875
pilocytic astrocytoma 11 | 3,086
Breast cancer 10 | 3,099
adult high grade glioma 10 | 2,148
Multiple myeloma 9 | 1,328
astrocytoma 9 | 1,493
ependymoma 9 | 2,514
invasive ductal carcinoma 9 | 2,950
malignant mesothelioma 9 | 3,163
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
pediatric high grade glioma 9 | 2,712
pituitary cancer 9 | 1,972
ulcerative colitis 9 | 2,087
cystic fibrosis 8 | 1,670
non-small cell lung cancer 8 | 2,798
Cancer 7 | 2,346
active Crohn's disease 7 | 918
atypical teratoid/rhabdoid tumor 7 | 1,095
interstitial cystitis 7 | 2,299
oligodendroglioma 7 | 2,849
posterior fossa group A ependymoma 7 | 1,511
primary pancreatic ductal adenocarcinoma 7 | 1,271
spina bifida 7 | 1,064
subependymal giant cell astrocytoma 7 | 2,287
astrocytic glioma 6 | 2,241
diabetes mellitus 6 | 1,663
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,189
primitive neuroectodermal tumor 6 | 3,031
tuberculosis 6 | 1,563
Amyotrophic Lateral Sclerosis 5 | 432
Pick disease 5 | 1,893
acute quadriplegic myopathy 5 | 1,157
breast carcinoma 5 | 1,614
hereditary spastic paraplegia 5 | 313
pancreatic carcinoma 5 | 567
Alzheimer's disease 4 | 644
IGA Glomerulonephritis 4 | 454
acute myeloid leukemia 4 | 785
dermatomyositis 4 | 967
fibroadenoma 4 | 557
non primary Sjogren syndrome sicca 4 | 840
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis and treatment for 6 months 4 | 686
Carcinoma 3 | 2,147
Desbuquois dysplasia 3 | 9
Duchenne muscular dystrophy 3 | 602
Rheumatoid Arthritis 3 | 1,171
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 832
lung carcinoma 3 | 2,844
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
posterior fossa group B ependymoma 3 | 1,530
primary Sjogren syndrome 3 | 789
Barrett's esophagus 2 | 185
Cardiovascular system disease 2 | 194
Chylomicron retention disease 2 | 11
Craniofacial Abnormalities 2 | 147
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Ehlers-Danlos syndrome 2 | 42
Hyperostosis 2 | 16
Hyperphosphatemia 2 | 32
Intellectual disability 2 | 573
Larsen syndrome 2 | 11
Leukocyte adhesion deficiency 2 | 15
Lipid metabolism disorder 2 | 102
Neuroblastoma 2 | 78
Prostatic Neoplasms 2 | 471
Radioulnar synostosis 2 | 13
Sclerocornea 2 | 16
Spondyloepiphyseal dysplasia with congenital joint dislocations 2 | 12
Type 2 diabetes mellitus 2 | 192
active ulcerative colitis 2 | 477
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,475
cutaneous lupus erythematosus 2 | 1,056
gastric cancer 2 | 436
group 3 medulloblastoma 2 | 2,254
hepatocellular carcinoma 2 | 550
mucosa-associated lymphoid tissue lymphoma 2 | 480
periodontitis 2 | 269
progressive supranuclear palsy 2 | 674
thrombocytopenia-absent radius syndrome 2 | 15
tuberculosis and treatment for 3 months 2 | 327

Tissue

Nervous System 70 | 18,561
Digestive Tract 69 | 18,473
Male tissues 69 | 17,969
Blood and immune system 68 | 17,995
Endocrine System 68 | 18,512
Female tissues 68 | 18,647
Liver and Pancreas 68 | 18,136
Respiratory system 68 | 17,484
Skin and soft tissues 68 | 18,115
Urinary Tract 68 | 18,444
Cardiovascular System 67 | 17,958

Target Family

Enzyme 48 | 4,146
Non-IDG 21 | 11,969
Ion Channel 2 | 341

Compartment GO Term

Golgi cisterna membrane 71 | 71
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Soluble calcium-activated nucleotidase 1 CANT1 Tbio Enzyme -1.42022 25.3 175
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.85200 7.21 86
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.46179 31.8 115
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ARAP1 Tbio Non-IDG -0.97819 13.6 86
Neuron-specific protein family member 2 NSG2 Tdark Non-IDG -1.54469 31.1 43
MOB-like protein phocein MOB4 Tbio Non-IDG -1.35818 24.2 101
Golgi pH regulator B GPR89B Tdark Ion Channel -0.62815 6.52 32
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 ASAP2 Tbio Non-IDG -1.14527 15.0 69
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.31506 197.5 112
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.31835 22.7 168