Development Level

Tbio 51 | 11,178
Tdark 11 | 6,569
Tchem 8 | 1,885

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
abnormal eye morphology 3 | 68
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
edema 2 | 59
increased mean corpuscular hem... 2 | 96
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal tail movements 1 | 12
anophthalmia 1 | 33
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating potassiu... 1 | 20
decreased pulmonary respirator... 1 | 5
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
increased CD8-positive, alpha-... 1 | 1
increased T cell number 1 | 6
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
polydactyly 1 | 7
short tibia 1 | 97
thick skin 1 | 4
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 44 | 8,297
Carcinoma 43 | 11,192
glioblastoma 29 | 5,635
osteosarcoma 28 | 7,766
psoriasis 27 | 6,514
medulloblastoma, large-cell 24 | 6,086
atypical teratoid / rhabdoid tumor 19 | 4,971
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,902
ependymoma 18 | 4,559
lung cancer 17 | 4,607
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,204
pancreatic cancer 14 | 2,322
lung adenocarcinoma 13 | 2,627
Astrocytoma, Pilocytic 11 | 3,006
adult high grade glioma 11 | 3,701
Multiple myeloma 10 | 1,296
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,911
Breast cancer 9 | 3,469
group 4 medulloblastoma 9 | 1,806
invasive ductal carcinoma 9 | 2,867
malignant mesothelioma 9 | 3,135
pituitary cancer 9 | 1,915
Cancer 8 | 2,388
astrocytoma 8 | 1,113
cystic fibrosis 8 | 1,629
group 3 medulloblastoma 8 | 4,002
non-small cell lung cancer 8 | 2,799
pediatric high grade glioma 8 | 1,035
tuberculosis 8 | 1,963
active Crohn's disease 7 | 882
interstitial cystitis 7 | 2,237
oligodendroglioma 7 | 2,768
spina bifida 7 | 1,053
subependymal giant cell astrocytoma 7 | 2,230
ulcerative colitis 7 | 1,765
Amyotrophic lateral sclerosis 6 | 437
diabetes mellitus 6 | 1,683
esophageal adenocarcinoma 6 | 696
juvenile dermatomyositis 6 | 1,147
primary pancreatic ductal adenocarcinoma 6 | 1,071
primitive neuroectodermal tumor 6 | 2,957
Alzheimer's disease 5 | 640
Kidney cancer 5 | 2,548
Pick disease 5 | 1,856
astrocytic glioma 5 | 2,530
breast carcinoma 5 | 1,589
dermatomyositis 5 | 941
hereditary spastic paraplegia 5 | 313
non primary Sjogren syndrome sicca 5 | 861
Autosomal recessive predisposition 4 | 1,407
Schizophrenia 4 | 1,136
active ulcerative colitis 4 | 736
acute quadriplegic myopathy 4 | 1,133
fibroadenoma 4 | 538
pancreatic carcinoma 4 | 555
Cardiovascular system disease 3 | 240
Desbuquois dysplasia 3 | 13
Duchenne muscular dystrophy 3 | 587
Intellectual disability 3 | 998
Liver Cirrhosis, Experimental 3 | 733
Obesity 3 | 655
Rheumatoid arthritis 3 | 1,156
Type 2 diabetes mellitus 3 | 268
Waldenstrons macroglobulinemia 3 | 742
acute myeloid leukemia 3 | 760
aldosterone-producing adenoma 3 | 646
atypical teratoid/rhabdoid tumor 3 | 349
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 492
ductal carcinoma in situ 3 | 1,686
gastric carcinoma 3 | 781
lung carcinoma 3 | 2,755
nasopharyngeal carcinoma 3 | 1,024
primary Sjogren syndrome 3 | 710
Big calvaria 2 | 147
Bipolar Disorder 2 | 646
Chylomicron retention disease 2 | 11
Diarrhea 2 | 245
Failure to gain weight 2 | 359
Hyperphosphatemia 2 | 29
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Influenza 2 | 136
Lipid metabolism disorder 2 | 111
Multiple Sclerosis 2 | 527
Neuroblastoma 2 | 79
Pediatric failure to thrive 2 | 359
Prostatic Neoplasms 2 | 472
Radioulnar synostosis 2 | 35
chronic rhinosinusitis 2 | 505
colon cancer 2 | 1,428
cutaneous lupus erythematosus 2 | 1,016
gastric cancer 2 | 445
medulloblastoma 2 | 702
mucosa-associated lymphoid tissue lymphoma 2 | 473
periodontitis 2 | 280
progressive supranuclear palsy 2 | 656
sonic hedgehog group medulloblastoma 2 | 459
tuberculosis and treatment for 6 months 2 | 399

Tissue

Endocrine System 68 | 18,159
Female tissues 67 | 17,400
Nervous System 67 | 16,725
Digestive Tract 66 | 17,369
Liver and Pancreas 66 | 16,750
Male tissues 66 | 17,142
Urinary Tract 66 | 16,678
Blood and immune system 65 | 16,909
Skin and soft tissues 65 | 17,230
Cardiovascular System 64 | 15,192
Respiratory system 64 | 16,393

Target Family

Enzyme 48 | 4,145
Non-IDG 20 | 12,091
Ion Channel 2 | 344

Compartment GO Term

Golgi cisterna membrane 70 | 70
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
Chondroitin sulfate glucuronyltransferase CHPF2 Tbio Enzyme -0.51521 3.67 74
Membrane-associated phosphatidylinositol transfer protein 1 PITPNM1 Tbio Non-IDG -1.99576 100.1 173
Sortilin SORT1 Tchem Non-IDG -2.36389 235.8 137
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 ASAP2 Tbio Non-IDG -1.14527 15.1 71
Beta-1,4-galactosyltransferase 2 B4GALT2 Tbio Enzyme -0.88995 7.16 122
Beta-galactoside alpha-2,6-sialyltransferase 2 ST6GAL2 Tbio Enzyme -0.94585 7.53 77
Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 Tbio Enzyme -2.80894 644.1 124
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170