Development Level

Tbio 71 | 11,651
Tdark 16 | 6,593
Tchem 6 | 1,388

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
edema 4 | 59
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal craniofacial morpholo... 3 | 33
abnormal eye morphology 3 | 68
abnormal limb morphology 3 | 13
anophthalmia 3 | 33
polydactyly 3 | 7
abnormal body wall morphology 2 | 9
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal facial morphology 2 | 17
abnormal limb bud morphology 2 | 17
abnormal tail movements 2 | 12
cleft palate 2 | 8
decreased circulating alanine ... 2 | 47
decreased total body fat amoun... 2 | 207
facial cleft 2 | 3
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal response to new envir... 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
decreased pulmonary respirator... 1 | 5
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
increased CD8-positive, alpha-... 1 | 1
increased T cell number 1 | 6
increased circulating amylase ... 1 | 25
increased circulating free fat... 1 | 20
increased circulating magnesiu... 1 | 10
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
short tibia 1 | 97
thick skin 1 | 4
thrombocytopenia 1 | 56
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 59 | 11,493
ovarian cancer 59 | 8,520
osteosarcoma 40 | 7,950
psoriasis 39 | 6,694
glioblastoma 37 | 5,792
medulloblastoma, large-cell 34 | 6,241
atypical teratoid / rhabdoid tumor 25 | 5,112
ependymoma 24 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
lung cancer 23 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
pancreatic cancer 16 | 2,398
lung adenocarcinoma 15 | 2,716
group 4 medulloblastoma 14 | 1,855
malignant mesothelioma 14 | 3,232
Breast cancer 13 | 3,578
adult high grade glioma 13 | 3,801
group 3 medulloblastoma 13 | 4,104
invasive ductal carcinoma 13 | 2,951
Multiple myeloma 12 | 1,332
cystic fibrosis 12 | 1,696
tuberculosis 12 | 2,010
astrocytoma 11 | 1,146
interstitial cystitis 11 | 2,312
oligodendroglioma 11 | 2,850
pediatric high grade glioma 11 | 1,064
pituitary cancer 10 | 1,972
Kidney cancer 9 | 2,613
astrocytic glioma 9 | 2,597
non-small cell lung cancer 9 | 2,890
primitive neuroectodermal tumor 9 | 3,035
spina bifida 9 | 1,074
subependymal giant cell astrocytoma 9 | 2,287
ulcerative colitis 9 | 1,819
Cancer 8 | 2,499
Pick disease 8 | 1,894
active Crohn's disease 8 | 922
dermatomyositis 8 | 966
juvenile dermatomyositis 8 | 1,187
lung carcinoma 8 | 2,843
Waldenstrons macroglobulinemia 7 | 765
active ulcerative colitis 7 | 764
acute quadriplegic myopathy 7 | 1,158
diabetes mellitus 7 | 1,728
non primary Sjogren syndrome sicca 7 | 891
primary pancreatic ductal adenocarcinoma 7 | 1,109
Alzheimer's disease 6 | 658
Amyotrophic lateral sclerosis 6 | 451
esophageal adenocarcinoma 6 | 737
hereditary spastic paraplegia 6 | 318
Autosomal recessive predisposition 5 | 1,442
Liver Cirrhosis, Experimental 5 | 769
atypical teratoid/rhabdoid tumor 5 | 357
breast carcinoma 5 | 1,638
primary Sjogren syndrome 5 | 735
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
aldosterone-producing adenoma 4 | 665
ductal carcinoma in situ 4 | 1,745
fibroadenoma 4 | 559
gastric carcinoma 4 | 807
mucosa-associated lymphoid tissue lymphoma 4 | 484
pancreatic carcinoma 4 | 562
progressive supranuclear palsy 4 | 676
sonic hedgehog group medulloblastoma 4 | 467
Bipolar Disorder 3 | 666
Cardiovascular system disease 3 | 246
Chronic Lymphocytic Leukemia 3 | 262
Cognitive delay 3 | 608
Congenital disorder of glycosylation 3 | 54
Desbuquois dysplasia 3 | 13
Diarrhea 3 | 253
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
Hyperphosphatemia 3 | 32
Intellectual disability 3 | 1,016
Mental and motor retardation 3 | 608
Muscle hypotonia 3 | 571
Neurodegenerative disease 3 | 414
Obesity 3 | 678
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Type 2 diabetes mellitus 3 | 272
acute myeloid leukemia 3 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
periodontitis 3 | 293
posterior fossa group A ependymoma 3 | 468
tuberculosis and treatment for 6 months 3 | 409
Epilepsy 2 | 792
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478

Tissue

Endocrine System 89 | 18,159
Female tissues 88 | 17,400
Nervous System 88 | 16,725
Digestive Tract 87 | 17,369
Liver and Pancreas 87 | 16,750
Male tissues 87 | 17,142
Urinary Tract 87 | 16,678
Blood and immune system 86 | 16,909
Skin and soft tissues 86 | 17,230
Respiratory system 85 | 16,393
Cardiovascular System 84 | 15,192

Target Family

Enzyme 55 | 4,145
Non-IDG 36 | 12,091
Ion Channel 2 | 344

Compartment GO Term

Golgi cisterna 93 | 93
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 Tbio Enzyme -2.80894 644.1 124
Beta-1,3-galactosyltransferase 6 B3GALT6 Tbio Enzyme -1.00350 10.1 132
Alpha-(1,3)-fucosyltransferase 7 FUT7 Tchem Enzyme -1.85814 81.0 121
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase ALG12 Tbio Enzyme -1.10352 13.0 65
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.88151 7.21 111
Soluble calcium-activated nucleotidase 1 CANT1 Tbio Enzyme -1.42839 27.2 210
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ST3GAL4 Tbio Enzyme -2.19681 149.3 89