Development Level

Tbio 714 | 10,625
Tdark 114 | 7,003
Tchem 100 | 1,890
Tclin 12 | 602

Collection

Eligible Kinase Proteins 6 | 134
Eligible Ion Channel Proteins 2 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 39 | 633
preweaning lethality, incomple... 16 | 260
decreased total body fat amoun... 15 | 186
embryonic lethality prior to t... 15 | 187
decreased bone mineral content 14 | 157
decreased lean body mass 14 | 195
abnormal bone structure 13 | 131
abnormal behavior 11 | 226
decreased circulating HDL chol... 11 | 77
decreased grip strength 10 | 123
decreased body length 9 | 108
decreased bone mineral density 9 | 126
decreased circulating alanine ... 9 | 53
decreased circulating choleste... 9 | 85
increased mean corpuscular hem... 9 | 93
increased mean corpuscular vol... 9 | 91
abnormal sleep behavior 8 | 63
decreased body weight 8 | 174
decreased circulating triglyce... 8 | 83
enlarged heart 8 | 111
increased bone mineral content 8 | 92
increased or absent threshold ... 8 | 128
abnormal lens morphology 7 | 73
decreased circulating LDL chol... 7 | 37
decreased circulating serum al... 7 | 79
hypoactivity 7 | 89
increased circulating alkaline... 7 | 119
increased heart weight 7 | 37
increased lean body mass 7 | 107
abnormal QRS complex 6 | 25
abnormal bone mineralization 6 | 55
abnormal embryo size 6 | 112
abnormal limb bud morphology 6 | 15
abnormal retina morphology 6 | 100
decreased circulating insulin ... 6 | 75
decreased prepulse inhibition 6 | 52
embryonic lethality prior to o... 6 | 148
hyperactivity 6 | 108
male infertility 6 | 62
abnormal limb morphology 5 | 7
decreased circulating glucose ... 5 | 121
decreased fasted circulating g... 5 | 49
decreased lumbar vertebrae num... 5 | 62
increased grip strength 5 | 83
abnormal behavioral response t... 4 | 52
abnormal eye morphology 4 | 38
abnormal facial morphology 4 | 9
abnormal retinal pigmentation 4 | 61
abnormal tail morphology 4 | 17
cardiovascular system phenotyp... 4 | 35
decreased caudal vertebrae num... 4 | 49
decreased heart weight 4 | 44
decreased vertical activity 4 | 22
hydrops fetalis 4 | 22
increased blood urea nitrogen ... 4 | 44
increased bone mineral density 4 | 52
increased circulating sodium l... 4 | 71
increased sacral vertebrae num... 4 | 62
straub tail 4 | 26
abnormal body wall morphology 3 | 7
abnormal coat/hair pigmentatio... 3 | 54
abnormal craniofacial morpholo... 3 | 12
abnormal epididymis morphology 3 | 31
abnormal kidney morphology 3 | 30
abnormal neural tube closure 3 | 37
abnormal testis morphology 3 | 30
anophthalmia 3 | 20
cataract 3 | 26
cleft palate 3 | 6
decreased CD8-positive, alpha-... 3 | 26
decreased NK T cell number 3 | 28
decreased T cell number 3 | 31
decreased circulating calcium ... 3 | 33
decreased hemoglobin content 3 | 53
decreased lactate dehydrogenas... 3 | 14
decreased leukocyte cell numbe... 3 | 54
decreased mean corpuscular hem... 3 | 34
decreased monocyte cell number 3 | 28
decreased rib number 3 | 59
decreased startle reflex 3 | 48
edema 3 | 11
enlarged epididymis 3 | 27
enlarged spleen 3 | 26
hemorrhage 3 | 12
impaired glucose tolerance 3 | 52
increased body weight 3 | 42
increased circulating chloride... 3 | 43
increased erythrocyte cell num... 3 | 26
increased exploration in new e... 3 | 56
increased fasted circulating g... 3 | 68
increased mean corpuscular hem... 3 | 25
increased startle reflex 3 | 38
increased total body fat amoun... 3 | 57
increased vertical activity 3 | 18
mydriasis 3 | 9
polydactyly 3 | 22
short tibia 3 | 82
tremors 3 | 34
abnormal vibrissa morphology 2 | 17
decreased circulating glycerol... 2 | 19

Disease

ovarian cancer 500 | 8,484
osteosarcoma 426 | 7,933
psoriasis 393 | 6,685
glioblastoma 337 | 5,572
medulloblastoma, large-cell 333 | 6,234
atypical teratoid / rhabdoid tumor 254 | 4,369
lung cancer 237 | 4,466
pilocytic astrocytoma 214 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 201 | 2,956
Cancer 200 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 194 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 192 | 2,988
Breast cancer 182 | 3,094
invasive ductal carcinoma 182 | 2,950
lung carcinoma 179 | 2,844
lung adenocarcinoma 166 | 2,713
pancreatic cancer 162 | 2,300
malignant mesothelioma 159 | 3,162
diabetes mellitus 156 | 1,663
oligodendroglioma 146 | 2,849
pediatric high grade glioma 145 | 2,712
non-small cell lung cancer 135 | 2,798
primitive neuroectodermal tumor 134 | 3,031
pituitary cancer 132 | 1,972
adult high grade glioma 127 | 2,148
ependymoma 127 | 2,514
Carcinoma 122 | 2,147
interstitial cystitis 121 | 2,299
astrocytic glioma 119 | 2,241
group 4 medulloblastoma 118 | 1,875
subependymal giant cell astrocytoma 115 | 2,287
Rheumatoid Arthritis 113 | 1,160
Pick disease 110 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 108 | 1,795
ulcerative colitis 108 | 2,087
ductal carcinoma in situ 104 | 1,745
astrocytoma 102 | 1,493
cystic fibrosis 99 | 1,665
posterior fossa group A ependymoma 97 | 1,511
breast carcinoma 96 | 1,614
group 3 medulloblastoma 88 | 2,254
primary pancreatic ductal adenocarcinoma 88 | 1,271
tuberculosis 86 | 1,557
juvenile dermatomyositis 84 | 1,189
Multiple myeloma 83 | 1,327
posterior fossa group B ependymoma 79 | 1,530
medulloblastoma 75 | 1,524
Ankylosing spondylitis 74 | 138
Hypersensitivity reaction type II disease 73 | 235
adrenocortical carcinoma 73 | 1,427
active Crohn's disease 70 | 918
colon cancer 69 | 1,475
sonic hedgehog group medulloblastoma 69 | 1,482
Arthritis 68 | 248
acute quadriplegic myopathy 66 | 1,157
dermatomyositis 64 | 933
Acquired immunodeficiency syndrome 61 | 164
Juvenile rheumatoid arthritis 61 | 104
Uveitis 60 | 103
Alzheimer's disease 59 | 644
spina bifida 58 | 1,064
Multiple Sclerosis 57 | 498
Behcet's disease 56 | 74
atypical teratoid/rhabdoid tumor 53 | 1,095
Psoriatic arthritis 52 | 83
gastric carcinoma 52 | 832
cutaneous lupus erythematosus 51 | 1,056
primary Sjogren syndrome 50 | 789
Kidney disease 49 | 396
nasopharyngeal carcinoma 49 | 1,056
non primary Sjogren syndrome sicca 49 | 840
tuberculosis and treatment for 6 months 48 | 686
Liver disease 46 | 219
esophageal adenocarcinoma 46 | 737
aldosterone-producing adenoma 45 | 664
Down syndrome 44 | 548
Atopic dermatitis 43 | 944
active ulcerative colitis 42 | 477
pancreatic carcinoma 42 | 567
Duchenne muscular dystrophy 41 | 602
Stevens-Johnson syndrome 40 | 78
Intellectual disability 39 | 573
Waldenstrons macroglobulinemia 39 | 765
Neurodegenerative disease 38 | 383
Anemia 36 | 252
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Takayasu's arteritis 35 | 52
acute myeloid leukemia 35 | 780
Hepatitis B 34 | 103
progressive supranuclear palsy 33 | 674
fibroadenoma 32 | 557
hepatocellular carcinoma 32 | 532
Prostatic Neoplasms 31 | 471
Obesity 30 | 616
autosomal dominant Emery-Dreifuss muscular dystrophy 30 | 499
IGA Glomerulonephritis 29 | 454
hereditary spastic paraplegia 29 | 313
inflammatory breast cancer 28 | 404
Schizophrenia 27 | 501

Tissue

Nervous System 861 | 18,561
Female tissues 858 | 18,647
Digestive Tract 857 | 18,473
Endocrine System 857 | 18,512
Cardiovascular System 856 | 17,958
Liver and Pancreas 855 | 18,136
Urinary Tract 855 | 18,444
Blood and immune system 852 | 17,995
Male tissues 851 | 17,969
Respiratory system 843 | 17,484
Skin and soft tissues 842 | 18,115

Target Family

Non-IDG 530 | 11,971
Enzyme 336 | 4,146
Transporter 31 | 473
Kinase 18 | 634
Transcription Factor 10 | 1,400
Ion Channel 8 | 341
GPCR 7 | 406

Compartment GO Term

Golgi apparatus part 940 | 940
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Probable phospholipid-transporting ATPase IIB ATP9B Tdark Transporter -0.57248 3.74 5
Monocarboxylate transporter 13 SLC16A13 Tdark Transporter -0.40437 1.87 71
HLA class I histocompatibility antigen, Cw-5 alpha chain HLA-C Tbio Non-IDG 777.4 0
Beta-galactoside alpha-2,6-sialyltransferase 1 ST6GAL1 Tchem Enzyme -2.37851 255.2 269
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
Beta-1,4 N-acetylgalactosaminyltransferase 1 B4GALNT1 Tbio Enzyme -1.85387 67.6 146
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A MGAT5 Tchem Enzyme -2.07315 133.7 104