Development Level

Tbio 1,018 | 10,625
Tdark 177 | 7,003
Tchem 166 | 1,890
Tclin 41 | 602

Collection

Eligible Kinase Proteins 9 | 134
Eligible Ion Channel Proteins 5 | 117
Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

preweaning lethality, complete... 61 | 633
preweaning lethality, incomple... 25 | 260
decreased total body fat amoun... 24 | 186
decreased lean body mass 23 | 195
embryonic lethality prior to t... 22 | 187
decreased bone mineral content 20 | 157
abnormal bone structure 19 | 131
decreased body weight 19 | 174
abnormal behavior 17 | 226
increased mean corpuscular hem... 15 | 93
decreased grip strength 13 | 123
increased lean body mass 13 | 107
increased mean corpuscular vol... 13 | 91
decreased body length 12 | 108
decreased bone mineral density 12 | 126
increased bone mineral content 12 | 92
decreased circulating HDL chol... 11 | 77
decreased circulating serum al... 11 | 79
increased circulating alkaline... 11 | 119
abnormal embryo size 10 | 112
embryonic lethality prior to o... 10 | 148
hyperactivity 10 | 108
increased or absent threshold ... 10 | 128
abnormal bone mineralization 9 | 55
abnormal lens morphology 9 | 73
decreased circulating alanine ... 9 | 53
decreased circulating choleste... 9 | 85
decreased circulating glucose ... 9 | 121
decreased circulating triglyce... 9 | 83
decreased prepulse inhibition 9 | 52
abnormal retina morphology 8 | 100
abnormal sleep behavior 8 | 63
decreased circulating LDL chol... 8 | 37
enlarged heart 8 | 111
increased blood urea nitrogen ... 8 | 44
increased heart weight 8 | 37
abnormal limb bud morphology 7 | 15
decreased circulating insulin ... 7 | 75
decreased fasted circulating g... 7 | 49
decreased lumbar vertebrae num... 7 | 62
hypoactivity 7 | 89
increased circulating sodium l... 7 | 71
short tibia 7 | 82
abnormal QRS complex 6 | 25
decreased leukocyte cell numbe... 6 | 54
increased sacral vertebrae num... 6 | 62
male infertility 6 | 62
straub tail 6 | 26
abnormal behavioral response t... 5 | 52
abnormal gait 5 | 51
abnormal limb morphology 5 | 7
abnormal neural tube closure 5 | 37
cardiovascular system phenotyp... 5 | 35
decreased erythrocyte cell num... 5 | 43
decreased hemoglobin content 5 | 53
hemorrhage 5 | 12
impaired glucose tolerance 5 | 52
increased bone mineral density 5 | 52
increased fasted circulating g... 5 | 68
increased grip strength 5 | 83
limb grasping 5 | 35
abnormal coat/hair pigmentatio... 4 | 54
abnormal cranium morphology 4 | 32
abnormal epididymis morphology 4 | 31
abnormal eye morphology 4 | 38
abnormal facial morphology 4 | 9
abnormal head morphology 4 | 10
abnormal kidney morphology 4 | 30
abnormal locomotor activation 4 | 26
abnormal retinal pigmentation 4 | 61
abnormal tail morphology 4 | 17
cataract 4 | 26
decreased caudal vertebrae num... 4 | 49
decreased circulating fructosa... 4 | 31
decreased heart weight 4 | 44
decreased hematocrit 4 | 25
decreased monocyte cell number 4 | 28
decreased rib number 4 | 59
decreased vertical activity 4 | 22
edema 4 | 11
enlarged epididymis 4 | 27
hydrops fetalis 4 | 22
increased circulating HDL chol... 4 | 63
increased mean corpuscular hem... 4 | 25
increased red blood cell distr... 4 | 21
abnormal coat appearance 3 | 25
anophthalmia 3 | 20
decreased circulating calcium ... 3 | 33
enlarged spleen 3 | 26
increased body weight 3 | 42
increased circulating bilirubi... 3 | 16
increased circulating chloride... 3 | 43
increased circulating serum al... 3 | 25
increased erythrocyte cell num... 3 | 26
increased exploration in new e... 3 | 56
increased hemoglobin content 3 | 45
increased prepulse inhibition 3 | 21
increased total body fat amoun... 3 | 57
thrombocytosis 3 | 23
tremors 3 | 34

Disease

ovarian cancer 782 | 8,484
osteosarcoma 656 | 7,933
psoriasis 560 | 6,685
medulloblastoma, large-cell 520 | 6,234
glioblastoma 519 | 5,572
atypical teratoid / rhabdoid tumor 388 | 4,369
lung cancer 378 | 4,466
pilocytic astrocytoma 315 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 303 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 303 | 3,289
Cancer 299 | 2,346
invasive ductal carcinoma 290 | 2,950
Breast cancer 287 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 283 | 2,988
malignant mesothelioma 276 | 3,162
lung carcinoma 268 | 2,844
lung adenocarcinoma 254 | 2,713
pancreatic cancer 249 | 2,300
oligodendroglioma 244 | 2,849
pediatric high grade glioma 234 | 2,712
non-small cell lung cancer 224 | 2,798
diabetes mellitus 215 | 1,663
primitive neuroectodermal tumor 213 | 3,031
ependymoma 211 | 2,514
subependymal giant cell astrocytoma 201 | 2,287
pituitary cancer 195 | 1,972
interstitial cystitis 192 | 2,299
adult high grade glioma 191 | 2,148
Carcinoma 189 | 2,147
ulcerative colitis 186 | 2,087
group 4 medulloblastoma 182 | 1,875
astrocytic glioma 180 | 2,241
Pick disease 171 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 169 | 1,795
ductal carcinoma in situ 165 | 1,745
astrocytoma 162 | 1,493
cystic fibrosis 156 | 1,665
breast carcinoma 154 | 1,614
Multiple myeloma 149 | 1,327
group 3 medulloblastoma 147 | 2,254
Rheumatoid Arthritis 145 | 1,160
tuberculosis 145 | 1,557
juvenile dermatomyositis 141 | 1,189
posterior fossa group A ependymoma 136 | 1,511
posterior fossa group B ependymoma 133 | 1,530
primary pancreatic ductal adenocarcinoma 131 | 1,271
colon cancer 122 | 1,475
adrenocortical carcinoma 120 | 1,427
medulloblastoma 119 | 1,524
sonic hedgehog group medulloblastoma 107 | 1,482
acute quadriplegic myopathy 106 | 1,157
dermatomyositis 103 | 933
active Crohn's disease 102 | 918
spina bifida 102 | 1,064
cutaneous lupus erythematosus 96 | 1,056
Alzheimer's disease 90 | 644
atypical teratoid/rhabdoid tumor 85 | 1,095
nasopharyngeal carcinoma 84 | 1,056
gastric carcinoma 81 | 832
Hypersensitivity reaction type II disease 80 | 235
non primary Sjogren syndrome sicca 80 | 840
tuberculosis and treatment for 6 months 78 | 686
Arthritis 77 | 248
Multiple Sclerosis 76 | 498
primary Sjogren syndrome 76 | 789
Ankylosing spondylitis 75 | 138
esophageal adenocarcinoma 74 | 737
pancreatic carcinoma 72 | 567
Duchenne muscular dystrophy 70 | 602
Kidney disease 69 | 396
Atopic dermatitis 68 | 944
Down syndrome 67 | 548
Intellectual disability 67 | 573
Acquired immunodeficiency syndrome 65 | 164
Waldenstrons macroglobulinemia 65 | 765
Juvenile rheumatoid arthritis 63 | 104
active ulcerative colitis 62 | 477
aldosterone-producing adenoma 62 | 664
Neurodegenerative disease 61 | 383
Uveitis 61 | 103
Liver disease 58 | 219
acute myeloid leukemia 58 | 780
progressive supranuclear palsy 57 | 674
Behcet's disease 56 | 74
autosomal dominant Emery-Dreifuss muscular dystrophy 55 | 499
IGA Glomerulonephritis 54 | 454
Obesity 53 | 616
Schizophrenia 53 | 501
fibroadenoma 53 | 557
Psoriatic arthritis 52 | 83
hepatocellular carcinoma 52 | 532
Prostatic Neoplasms 47 | 471
gastric cancer 47 | 430
hereditary spastic paraplegia 47 | 313
mucosa-associated lymphoid tissue lymphoma 46 | 480
Amyotrophic Lateral Sclerosis 43 | 431
Stevens-Johnson syndrome 43 | 78
Parkinson's disease 42 | 364
Anemia 41 | 252
Heart disease 40 | 279

Tissue

Nervous System 1,317 | 18,561
Female tissues 1,316 | 18,647
Endocrine System 1,315 | 18,512
Digestive Tract 1,314 | 18,473
Liver and Pancreas 1,313 | 18,136
Urinary Tract 1,312 | 18,444
Cardiovascular System 1,311 | 17,958
Blood and immune system 1,307 | 17,995
Male tissues 1,306 | 17,969
Respiratory system 1,293 | 17,484
Skin and soft tissues 1,292 | 18,115

Target Family

Non-IDG 788 | 11,971
Enzyme 441 | 4,146
Kinase 49 | 634
Transporter 48 | 473
Transcription Factor 31 | 1,400
Ion Channel 17 | 341
GPCR 16 | 406
Epigenetic 9 | 242
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

Golgi apparatus 1,402 | 1,402
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Probable phospholipid-transporting ATPase IIB ATP9B Tdark Transporter -0.57248 3.74 5
Monocarboxylate transporter 13 SLC16A13 Tdark Transporter -0.40437 1.87 71
HLA class I histocompatibility antigen, Cw-5 alpha chain HLA-C Tbio Non-IDG 777.4 0
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.71996 60.7 178
Beta-galactoside alpha-2,6-sialyltransferase 1 ST6GAL1 Tchem Enzyme -2.37851 255.2 269