Development Level

Tbio 1,305 | 10,625
Tdark 372 | 7,003
Tchem 214 | 1,890
Tclin 55 | 602

Collection

Kinase: IDG Consortium (Targets) 12 | 125
Ion Channel: IDG Consortium (Targets) 9 | 102
Kinase: IDG Consortium (Complete/Control) 3 | 37
GPCR: IDG Consortium (Targets) 2 | 128

IMPC Phenotype

preweaning lethality, complete... 82 | 633
preweaning lethality, incomple... 31 | 260
decreased lean body mass 30 | 195
decreased total body fat amoun... 30 | 186
embryonic lethality prior to t... 29 | 187
decreased body weight 28 | 174
decreased bone mineral content 27 | 157
abnormal bone structure 24 | 131
abnormal behavior 23 | 226
decreased body length 17 | 108
decreased circulating serum al... 17 | 79
decreased bone mineral density 16 | 126
increased lean body mass 16 | 107
increased mean corpuscular hem... 16 | 93
increased mean corpuscular vol... 16 | 91
abnormal embryo size 15 | 112
increased or absent threshold ... 15 | 128
decreased grip strength 14 | 123
embryonic lethality prior to o... 14 | 148
increased bone mineral content 14 | 92
increased circulating alkaline... 14 | 119
short tibia 14 | 82
decreased circulating HDL chol... 13 | 77
decreased circulating alanine ... 12 | 53
decreased circulating choleste... 12 | 85
decreased circulating glucose ... 11 | 121
decreased circulating triglyce... 11 | 83
decreased prepulse inhibition 11 | 52
hyperactivity 11 | 108
abnormal bone mineralization 10 | 55
abnormal lens morphology 10 | 73
abnormal retina morphology 10 | 100
decreased circulating LDL chol... 10 | 37
decreased circulating insulin ... 10 | 75
decreased lumbar vertebrae num... 10 | 62
enlarged heart 10 | 111
abnormal sleep behavior 9 | 63
increased heart weight 9 | 37
decreased fasted circulating g... 8 | 49
decreased heart weight 8 | 44
hypoactivity 8 | 89
impaired glucose tolerance 8 | 52
increased blood urea nitrogen ... 8 | 44
increased circulating sodium l... 8 | 71
increased sacral vertebrae num... 8 | 62
abnormal limb bud morphology 7 | 15
decreased rib number 7 | 59
increased exploration in new e... 7 | 56
increased fasted circulating g... 7 | 68
prenatal lethality prior to he... 7 | 64
abnormal QRS complex 6 | 25
abnormal cranium morphology 6 | 32
abnormal eye morphology 6 | 38
abnormal gait 6 | 51
abnormal neural tube closure 6 | 37
abnormal rib morphology 6 | 28
cardiovascular system phenotyp... 6 | 35
decreased circulating fructosa... 6 | 31
decreased circulating total pr... 6 | 41
decreased erythrocyte cell num... 6 | 43
decreased hemoglobin content 6 | 53
decreased leukocyte cell numbe... 6 | 54
increased circulating potassiu... 6 | 31
increased grip strength 6 | 83
increased startle reflex 6 | 38
increased total body fat amoun... 6 | 57
increased vertical activity 6 | 18
male infertility 6 | 62
straub tail 6 | 26
abnormal behavioral response t... 5 | 52
abnormal coat-hair pigmentatio... 5 | 54
abnormal facial morphology 5 | 9
abnormal limb morphology 5 | 7
abnormal locomotor activation 5 | 26
abnormal retinal pigmentation 5 | 61
cataract 5 | 26
decreased caudal vertebrae num... 5 | 49
decreased circulating alkaline... 5 | 41
decreased circulating aspartat... 5 | 27
decreased circulating creatini... 5 | 31
decreased circulating free fat... 5 | 39
decreased lactate dehydrogenas... 5 | 14
decreased monocyte cell number 5 | 28
decreased startle reflex 5 | 48
decreased vertical activity 5 | 22
enlarged epididymis 5 | 27
hemorrhage 5 | 12
hydrops fetalis 5 | 22
increased bone mineral density 5 | 52
increased erythrocyte cell num... 5 | 26
increased mean corpuscular hem... 5 | 25
limb grasping 5 | 35
shortened RR interval 5 | 19
abnormal epididymis morphology 4 | 31
anophthalmia 4 | 20
improved glucose tolerance 4 | 56
increased body weight 4 | 42
increased circulating bilirubi... 4 | 16
increased heart rate 4 | 17
increased prepulse inhibition 4 | 21

Disease

ovarian cancer 1,057 | 8,491
osteosarcoma 926 | 7,933
psoriasis 755 | 6,685
medulloblastoma, large-cell 708 | 6,234
glioblastoma 682 | 5,572
atypical teratoid / rhabdoid tumor 517 | 4,369
lung cancer 513 | 4,473
intraductal papillary-mucinous neoplasm (IPMN) 418 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 417 | 2,956
pilocytic astrocytoma 407 | 3,086
invasive ductal carcinoma 405 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 390 | 2,988
Breast cancer 388 | 3,098
malignant mesothelioma 384 | 3,163
lung carcinoma 374 | 2,844
Cancer 355 | 2,346
pancreatic cancer 350 | 2,300
lung adenocarcinoma 333 | 2,714
oligodendroglioma 324 | 2,849
pediatric high grade glioma 322 | 2,712
non-small cell lung cancer 316 | 2,798
primitive neuroectodermal tumor 297 | 3,031
ependymoma 293 | 2,514
subependymal giant cell astrocytoma 275 | 2,287
interstitial cystitis 271 | 2,299
pituitary cancer 271 | 1,972
ulcerative colitis 265 | 2,087
adult high grade glioma 259 | 2,148
diabetes mellitus 256 | 1,663
Carcinoma 255 | 2,147
group 4 medulloblastoma 254 | 1,875
astrocytic glioma 244 | 2,241
Pick disease 239 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 231 | 1,795
cystic fibrosis 229 | 1,670
ductal carcinoma in situ 228 | 1,745
group 3 medulloblastoma 216 | 2,254
breast carcinoma 213 | 1,614
tuberculosis 211 | 1,563
astrocytoma 204 | 1,493
posterior fossa group A ependymoma 190 | 1,511
posterior fossa group B ependymoma 188 | 1,530
juvenile dermatomyositis 187 | 1,189
Multiple myeloma 185 | 1,327
primary pancreatic ductal adenocarcinoma 183 | 1,271
Rheumatoid Arthritis 178 | 1,170
dermatomyositis 168 | 966
adrenocortical carcinoma 165 | 1,427
colon cancer 165 | 1,475
medulloblastoma 161 | 1,524
sonic hedgehog group medulloblastoma 157 | 1,482
acute quadriplegic myopathy 145 | 1,157
spina bifida 137 | 1,064
active Crohn's disease 131 | 918
atypical teratoid/rhabdoid tumor 128 | 1,095
gastric carcinoma 123 | 832
cutaneous lupus erythematosus 122 | 1,056
nasopharyngeal carcinoma 115 | 1,056
Alzheimer's disease 110 | 644
esophageal adenocarcinoma 108 | 737
non primary Sjogren syndrome sicca 107 | 840
Duchenne muscular dystrophy 100 | 602
tuberculosis and treatment for 6 months 98 | 686
pancreatic carcinoma 97 | 567
Atopic dermatitis 95 | 944
primary Sjogren syndrome 91 | 788
Multiple Sclerosis 89 | 498
Hypersensitivity reaction type II disease 88 | 235
Down syndrome 85 | 548
Arthritis 84 | 248
Waldenstrons macroglobulinemia 84 | 764
Intellectual disability 83 | 573
aldosterone-producing adenoma 83 | 664
Kidney disease 81 | 397
acute myeloid leukemia 81 | 785
Obesity 80 | 616
active ulcerative colitis 80 | 477
autosomal dominant Emery-Dreifuss muscular dystrophy 80 | 499
Ankylosing spondylitis 78 | 138
hepatocellular carcinoma 76 | 550
progressive supranuclear palsy 75 | 674
Acquired immunodeficiency syndrome 70 | 164
fibroadenoma 70 | 557
Liver disease 68 | 219
Neurodegenerative disease 68 | 383
Juvenile rheumatoid arthritis 67 | 105
mucosa-associated lymphoid tissue lymphoma 65 | 480
Human immunodeficiency virus infectious disease 64 | 129
IGA Glomerulonephritis 64 | 454
gastric cancer 64 | 436
Uveitis 63 | 103
Prostatic Neoplasms 60 | 471
Schizophrenia 58 | 503
Endometriosis 57 | 535
Behcet's disease 56 | 74
Stevens-Johnson syndrome 56 | 91
hereditary spastic paraplegia 56 | 313
sarcoidosis 56 | 368
Heart disease 54 | 279
Polycystic Ovary Syndrome 54 | 334

Tissue

Nervous System 1,856 | 18,560
Female tissues 1,855 | 18,646
Endocrine System 1,853 | 18,511
Liver and Pancreas 1,853 | 18,135
Digestive Tract 1,852 | 18,472
Urinary Tract 1,849 | 18,443
Blood and immune system 1,845 | 17,994
Cardiovascular System 1,844 | 17,957
Male tissues 1,844 | 17,968
Respiratory system 1,829 | 17,483
Skin and soft tissues 1,827 | 18,114

Target Family

Non-IDG 1,139 | 11,969
Enzyme 555 | 4,146
Kinase 65 | 634
Transporter 64 | 473
Transcription Factor 62 | 1,400
Ion Channel 24 | 341
GPCR 18 | 408
Epigenetic 14 | 242
Nuclear Receptor 3 | 48
TF/Epigenetic 2 | 38

Compartment GO Term

Golgi apparatus 1,946 | 1,946
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
Synapse differentiation-inducing gene protein 1-like SYNDIG1L Tdark Non-IDG -0.55764 3.83 4
Neuron-specific protein family member 1 NSG1 Tbio Non-IDG -1.10592 14.0 156
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Trafficking protein particle complex subunit 9 TRAPPC9 Tbio Non-IDG -2.14008 133.3 71
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91708 86.7 133
RNA pseudouridylate synthase domain-containing protein 1 RPUSD1 Tdark Enzyme 0.00000 53
Protein YIPF1 YIPF1 Tbio Non-IDG -2.07470 81.5 69
N-acetylglucosamine-1-phosphotransferase subunit gamma GNPTG Tbio Enzyme -1.17901 15.7 80