Development Level

Tbio 1,390 | 11,445
Tdark 325 | 6,588
Tchem 164 | 1,598
Tclin 54 | 613

Collection

RFA-RM-18-021 22 | 328
Kinase: IDG Consortium (Target... 12 | 125
Ion Channel: IDG Consortium (T... 8 | 99
Kinase: IDG Consortium (Comple... 3 | 37
GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

preweaning lethality, complete... 118 | 979
preweaning lethality, incomple... 65 | 499
embryonic lethality prior to t... 41 | 278
decreased total body fat amoun... 30 | 207
abnormal behavior 29 | 298
abnormal bone structure 29 | 187
abnormal embryo size 29 | 220
embryonic lethality prior to o... 28 | 239
decreased body weight 24 | 161
decreased bone mineral content 23 | 151
decreased circulating serum al... 20 | 82
decreased vertical activity 20 | 208
increased lean body mass 20 | 172
decreased lean body mass 19 | 135
enlarged heart 19 | 210
increased startle reflex 18 | 112
hypoactivity 17 | 132
increased total body fat amoun... 17 | 134
short tibia 17 | 97
increased mean corpuscular vol... 16 | 92
embryonic growth retardation 15 | 106
abnormal kidney morphology 14 | 65
abnormal sleep behavior 14 | 70
decreased body length 14 | 101
decreased bone mineral density 14 | 126
decreased circulating glucose ... 14 | 126
hyperactivity 14 | 148
increased bone mineral content 14 | 108
increased mean corpuscular hem... 14 | 96
decreased circulating choleste... 13 | 93
decreased circulating triglyce... 13 | 79
increased heart weight 13 | 62
abnormal eye morphology 12 | 68
cataract 12 | 92
decreased grip strength 12 | 116
increased circulating alkaline... 12 | 122
increased or absent threshold ... 12 | 101
abnormal heart morphology 11 | 162
abnormal lens morphology 11 | 81
abnormal seminal vesicle morph... 11 | 114
decreased circulating HDL chol... 11 | 68
decreased circulating alanine ... 10 | 47
decreased circulating creatini... 10 | 39
edema 10 | 59
impaired glucose tolerance 10 | 75
small superior vagus ganglion 10 | 74
abnormal behavioral response t... 9 | 66
abnormal retina morphology 9 | 71
decreased circulating LDL chol... 9 | 38
decreased circulating insulin ... 9 | 76
increased bone mineral density 9 | 72
increased fasted circulating g... 9 | 76
abnormal gait 8 | 69
decreased circulating fructosa... 8 | 30
decreased circulating total pr... 8 | 49
decreased fasted circulating g... 8 | 65
decreased hemoglobin content 8 | 68
decreased lymphocyte cell numb... 8 | 83
decreased mean corpuscular hem... 8 | 50
decreased mean corpuscular vol... 8 | 79
decreased prepulse inhibition 8 | 82
increased blood urea nitrogen ... 8 | 48
increased monocyte cell number 8 | 63
abnormal craniofacial morpholo... 7 | 33
abnormal cranium morphology 7 | 36
abnormal neural tube closure 7 | 46
decreased erythrocyte cell num... 7 | 62
decreased leukocyte cell numbe... 7 | 73
decreased startle reflex 7 | 75
hydrometra 7 | 53
improved glucose tolerance 7 | 79
increased circulating sodium l... 7 | 71
increased heart rate 7 | 23
increased mean platelet volume 7 | 45
male infertility 7 | 123
abnormal coat-hair pigmentatio... 6 | 64
abnormal facial morphology 6 | 17
abnormal limb bud morphology 6 | 17
abnormal limb morphology 6 | 13
abnormal spleen morphology 6 | 55
anophthalmia 6 | 33
decreased circulating alkaline... 6 | 46
decreased circulating calcium ... 6 | 36
increased circulating HDL chol... 6 | 80
increased neutrophil cell numb... 6 | 46
limb grasping 6 | 41
prenatal lethality 6 | 28
prenatal lethality prior to he... 6 | 87
small testis 6 | 58
abnormal locomotor behavior 5 | 24
abnormal vibrissa morphology 5 | 25
cardiovascular system phenotyp... 5 | 36
decreased caudal vertebrae num... 5 | 53
decreased circulating aspartat... 5 | 34
decreased hematocrit 5 | 46
decreased lactate dehydrogenas... 5 | 16
enlarged kidney 5 | 14
increased body weight 5 | 25
increased circulating serum al... 5 | 22
thrombocytosis 5 | 27

Disease

Carcinoma 1,260 | 11,493
ovarian cancer 1,053 | 8,520
osteosarcoma 917 | 7,950
psoriasis 753 | 6,694
medulloblastoma, large-cell 696 | 6,241
glioblastoma 688 | 5,792
atypical teratoid / rhabdoid tumor 596 | 5,112
ependymoma 555 | 4,679
lung cancer 534 | 4,740
Breast cancer 437 | 3,578
adult high grade glioma 421 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 411 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 410 | 3,291
Astrocytoma, Pilocytic 403 | 3,081
malignant mesothelioma 397 | 3,232
group 3 medulloblastoma 391 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 388 | 2,989
invasive ductal carcinoma 385 | 2,951
lung carcinoma 365 | 2,843
Cancer 357 | 2,499
pancreatic cancer 348 | 2,398
lung adenocarcinoma 328 | 2,716
non-small cell lung cancer 326 | 2,890
Kidney cancer 319 | 2,613
oligodendroglioma 317 | 2,850
astrocytic glioma 283 | 2,597
primitive neuroectodermal tumor 283 | 3,035
tuberculosis 280 | 2,010
subependymal giant cell astrocytoma 267 | 2,287
interstitial cystitis 265 | 2,312
pituitary cancer 259 | 1,972
diabetes mellitus 258 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 255 | 1,962
group 4 medulloblastoma 251 | 1,855
Pick disease 239 | 1,894
ulcerative colitis 227 | 1,819
cystic fibrosis 223 | 1,696
ductal carcinoma in situ 217 | 1,745
breast carcinoma 207 | 1,638
juvenile dermatomyositis 185 | 1,187
Multiple myeloma 182 | 1,332
Rheumatoid arthritis 178 | 1,191
Autosomal recessive predisposition 175 | 1,442
dermatomyositis 165 | 966
adrenocortical carcinoma 164 | 1,428
colon cancer 161 | 1,478
primary pancreatic ductal adenocarcinoma 157 | 1,109
astrocytoma 155 | 1,146
Schizophrenia 149 | 1,160
acute quadriplegic myopathy 148 | 1,158
pediatric high grade glioma 146 | 1,064
Intellectual disability 141 | 1,016
spina bifida 133 | 1,074
active Crohn's disease 130 | 922
cutaneous lupus erythematosus 123 | 1,057
gastric carcinoma 120 | 807
active ulcerative colitis 118 | 764
non primary Sjogren syndrome sicca 113 | 891
nasopharyngeal carcinoma 110 | 1,058
Alzheimer's disease 109 | 658
esophageal adenocarcinoma 105 | 737
Liver Cirrhosis, Experimental 101 | 769
Duchenne muscular dystrophy 100 | 601
Epilepsy 99 | 792
Atopic dermatitis 95 | 952
Arthritis 92 | 290
pancreatic carcinoma 92 | 562
Obesity 91 | 678
Dull intelligence 90 | 645
Low intelligence 90 | 645
Mental Retardation 90 | 645
Mental deficiency 90 | 645
Multiple Sclerosis 90 | 540
Poor school performance 90 | 645
Hypersensitivity reaction type II disease 89 | 253
Kidney disease 87 | 430
Down syndrome 85 | 499
Liver cancer 85 | 604
Melanoma 85 | 711
Seizures 83 | 596
aldosterone-producing adenoma 82 | 665
Waldenstrons macroglobulinemia 81 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 80 | 510
Bipolar Disorder 79 | 666
primary Sjogren syndrome 78 | 735
Ankylosing spondylitis 77 | 140
Cognitive delay 76 | 608
Global developmental delay 76 | 608
Mental and motor retardation 76 | 608
progressive supranuclear palsy 76 | 676
Short stature 75 | 531
acute myeloid leukemia 75 | 783
Acquired immunodeficiency syndrome 74 | 197
hepatocellular carcinoma 74 | 547
Neurodegenerative disease 73 | 414
Behcet's disease 70 | 89
Liver disease 69 | 237
Muscle hypotonia 69 | 571
Human immunodeficiency virus infectious disease 67 | 138
gastric cancer 67 | 459

Tissue

Endocrine System 1,816 | 18,159
Digestive Tract 1,807 | 17,369
Female tissues 1,797 | 17,400
Skin and soft tissues 1,792 | 17,230
Male tissues 1,783 | 17,142
Blood and immune system 1,775 | 16,909
Nervous System 1,773 | 16,725
Liver and Pancreas 1,772 | 16,750
Urinary Tract 1,772 | 16,678
Respiratory system 1,752 | 16,393
Cardiovascular System 1,669 | 15,192

Target Family

Non-IDG 1,134 | 12,091
Enzyme 555 | 4,145
Transporter 66 | 473
Kinase 64 | 634
Transcription Factor 57 | 1,400
Ion Channel 22 | 344
GPCR 18 | 408
Epigenetic 14 | 242
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

Golgi apparatus 1,933 | 1,933
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Non-lysosomal glucosylceramidase GBA2 Tchem Enzyme -1.62330 43.1 59
Nck-associated protein 5-like NCKAP5L Tdark Non-IDG -0.22123 2.83 11
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 ST6GALNAC2 Tbio Enzyme -1.74190 55.6 59