Development Level

Tbio 30 | 11,445
Tchem 1 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased vertical activity 3 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hydrometra 2 | 53
increased or absent threshold ... 2 | 101
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased caudal vertebrae num... 1 | 53
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
edema 1 | 59
enlarged spleen 1 | 41
enlarged uterus 1 | 11
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Carcinoma 24 | 11,493
ovarian cancer 20 | 8,520
osteosarcoma 19 | 7,950
psoriasis 17 | 6,694
interstitial cystitis 13 | 2,312
Breast cancer 11 | 3,578
lung adenocarcinoma 11 | 2,716
lung cancer 11 | 4,740
Cancer 10 | 2,499
adult high grade glioma 10 | 3,801
medulloblastoma, large-cell 10 | 6,241
non-small cell lung cancer 10 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
malignant mesothelioma 9 | 3,232
primitive neuroectodermal tumor 9 | 3,035
Erythrokeratodermia variabilis 8 | 10
atypical teratoid / rhabdoid tumor 8 | 5,112
invasive ductal carcinoma 8 | 2,951
Kidney cancer 7 | 2,613
Oculodentodigital dysplasia 7 | 14
diabetes mellitus 7 | 1,728
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung carcinoma 7 | 2,843
Alopecia 6 | 115
Autosomal recessive predisposition 6 | 1,442
Cataract 6 | 297
Palmoplantar keratosis 6 | 74
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Astrocytoma, Pilocytic 5 | 3,081
Clouston syndrome 5 | 9
Dull intelligence 5 | 645
Infantile onset 5 | 238
Intellectual disability 5 | 1,016
Lens Opacities 5 | 231
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Nonsyndromic deafness 5 | 142
Poor school performance 5 | 645
Schizophrenia 5 | 1,160
Small head 5 | 374
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
pancreatic cancer 5 | 2,398
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Adenoma 4 | 167
Breast Neoplasms 4 | 445
Cardiomyopathy 4 | 116
Cerebrovascular disease 4 | 238
Conductive hearing loss 4 | 123
Deafness, autosomal recessive 1A 4 | 4
Epilepsy 4 | 792
Erythema 4 | 58
Flushing 4 | 60
Frontal bossing 4 | 157
Hyperkeratosis, generalized 4 | 14
Hypertension 4 | 396
Hypertensive disease 4 | 292
Inflammatory bowel disease 4 | 151
Liver cancer 4 | 604
Nail dysplasia 4 | 52
Neoplasm Metastasis 4 | 168
Neuropathy 4 | 261
Sensorineural hearing loss 4 | 106
Sparse eyelashes 4 | 31
adrenocortical carcinoma 4 | 1,428
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
Autistic Disorder 3 | 364
Bilateral fifth finger clinodactyly 3 | 110
Curvature of little finger 3 | 110
Disease Progression 3 | 136
Kidney disease 3 | 430
Long philtrum 3 | 137
Low Vision 3 | 174
Lung Neoplasms 3 | 232
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Myopia 3 | 176
Neoplasm Invasiveness 3 | 161
Neurodegenerative disease 3 | 414
Paraplegia 3 | 74
Prostatic Neoplasms 3 | 495
Skin cancer 3 | 469
Stomach Neoplasms 3 | 300
Strabismus 3 | 270
Thin lips 3 | 49
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pulmonary arterial hypertension 3 | 75
urothelial carcinoma 3 | 318

Tissue

Endocrine System 30 | 18,159
Female tissues 28 | 17,400
Digestive Tract 27 | 17,369
Liver and Pancreas 27 | 16,750
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Blood and immune system 25 | 16,909
Respiratory system 23 | 16,393
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 27 | 12,091
Ion Channel 3 | 344
Enzyme 1 | 4,145

Compartment GO Term

Gap junction 31 | 31
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pannexin-3 PANX3 Tbio Ion Channel -1.66465 45.0 71
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Pannexin-2 PANX2 Tbio Ion Channel -1.77864 56.1 126
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Gap junction alpha-4 protein GJA4 Tbio Non-IDG -2.27043 180.6 231
Desmoplakin DSP Tbio Non-IDG -2.95735 853.9 198
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194