Development Level

Tbio 170 | 11,445
Tchem 18 | 1,598
Tclin 4 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 22 | 979
preweaning lethality, incomple... 9 | 499
abnormal bone structure 8 | 187
increased startle reflex 7 | 112
abnormal behavior 6 | 298
abnormal retina morphology 5 | 71
abnormal embryo size 4 | 220
abnormal lens morphology 4 | 81
cataract 4 | 92
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
increased heart weight 4 | 62
abnormal sleep behavior 3 | 70
decreased bone mineral content 3 | 151
decreased circulating alanine ... 3 | 47
decreased hematocrit 3 | 46
edema 3 | 59
enlarged heart 3 | 210
hypoactivity 3 | 132
increased blood urea nitrogen ... 3 | 48
increased lean body mass 3 | 172
increased mean corpuscular hem... 3 | 96
persistence of hyaloid vascula... 3 | 33
short tibia 3 | 97
decreased caudal vertebrae num... 2 | 53
decreased circulating LDL chol... 2 | 38
decreased circulating aspartat... 2 | 34
decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
impaired pupillary reflex 2 | 26
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased circulating triglyce... 2 | 42
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
hydrometra 1 | 53
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
limb grasping 1 | 41
pallor 1 | 34
polycystic kidney 1 | 15
prenatal lethality 1 | 28
small testis 1 | 58
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 120 | 11,493
ovarian cancer 113 | 8,520
osteosarcoma 97 | 7,950
medulloblastoma, large-cell 96 | 6,241
glioblastoma 92 | 5,792
psoriasis 81 | 6,694
Cancer 73 | 2,499
atypical teratoid / rhabdoid tumor 71 | 5,112
ependymoma 61 | 4,679
lung cancer 60 | 4,740
adult high grade glioma 57 | 3,801
Breast cancer 55 | 3,578
subependymal giant cell astrocytoma 48 | 2,287
Astrocytoma, Pilocytic 46 | 3,081
group 3 medulloblastoma 45 | 4,104
primitive neuroectodermal tumor 45 | 3,035
oligodendroglioma 44 | 2,850
invasive ductal carcinoma 43 | 2,951
lung carcinoma 42 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,955
pancreatic cancer 40 | 2,398
astrocytic glioma 39 | 2,597
malignant mesothelioma 39 | 3,232
Kidney cancer 37 | 2,613
non-small cell lung cancer 37 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,989
Pick disease 35 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
lung adenocarcinoma 33 | 2,716
group 4 medulloblastoma 32 | 1,855
pituitary cancer 32 | 1,972
breast carcinoma 31 | 1,638
diabetes mellitus 31 | 1,728
tuberculosis 30 | 2,010
Multiple myeloma 27 | 1,332
Intellectual disability 26 | 1,016
ductal carcinoma in situ 25 | 1,745
interstitial cystitis 25 | 2,312
astrocytoma 23 | 1,146
colon cancer 23 | 1,478
ulcerative colitis 23 | 1,819
Schizophrenia 22 | 1,160
Obesity 20 | 678
Rheumatoid arthritis 19 | 1,191
acute quadriplegic myopathy 18 | 1,158
dermatomyositis 18 | 966
juvenile dermatomyositis 18 | 1,187
primary pancreatic ductal adenocarcinoma 18 | 1,109
adrenocortical carcinoma 17 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Liver Cirrhosis, Experimental 16 | 769
cystic fibrosis 16 | 1,696
Alzheimer's disease 15 | 658
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
pediatric high grade glioma 15 | 1,064
Autosomal recessive predisposition 14 | 1,442
Kidney disease 14 | 430
Polycystic ovary syndrome 14 | 360
cutaneous lupus erythematosus 14 | 1,057
spina bifida 14 | 1,074
Adenoma 13 | 167
Hypertension 13 | 396
Liver cancer 13 | 604
Melanoma 13 | 711
active ulcerative colitis 13 | 764
Breast Neoplasms 12 | 445
active Crohn's disease 12 | 922
Epilepsy 11 | 792
Mammary Neoplasms 11 | 425
Optic Atrophy 11 | 242
Parkinson's disease 11 | 392
medulloblastoma 11 | 720
non primary Sjogren syndrome sicca 11 | 891
Amyotrophic lateral sclerosis 10 | 451
Atopic dermatitis 10 | 952
Duchenne muscular dystrophy 10 | 601
Neoplasm Invasiveness 10 | 161
Neurodegenerative disease 10 | 414
Seizures 10 | 596
Skin cancer 10 | 469
Waldenstrons macroglobulinemia 10 | 765
esophageal adenocarcinoma 10 | 737
hereditary spastic paraplegia 10 | 318
primary Sjogren syndrome 10 | 735
Acquired scoliosis 9 | 281
Cognitive delay 9 | 608
Curvature of spine 9 | 282
Global developmental delay 9 | 608
Heart disease 9 | 306
Mental and motor retardation 9 | 608
Muscle hypotonia 9 | 571
Prostatic Neoplasms 9 | 495
Stomach Neoplasms 9 | 300
Vascular disease 9 | 319
gastric carcinoma 9 | 807
progressive supranuclear palsy 9 | 676

Tissue

Endocrine System 186 | 18,159
Digestive Tract 183 | 17,369
Female tissues 183 | 17,400
Nervous System 183 | 16,725
Liver and Pancreas 182 | 16,750
Male tissues 182 | 17,142
Skin and soft tissues 182 | 17,230
Blood and immune system 181 | 16,909
Respiratory system 180 | 16,393
Urinary Tract 179 | 16,678
Cardiovascular System 174 | 15,192

Target Family

Non-IDG 104 | 12,091
Enzyme 78 | 4,145
Kinase 8 | 634
GPCR 2 | 408
Transcription Factor 1 | 1,400
Transporter 1 | 473

Compartment GO Term

GTPase complex 194 | 194
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
ADP-ribosylation factor-related protein 1 ARFRP1 Tbio Enzyme -1.22088 20.8 63
MAP kinase-activating death domain protein MADD Tbio Enzyme -1.86555 79.6 121
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168