Development Level

Tclin 48 | 602
Tbio 45 | 10,625
Tdark 12 | 7,003
Tchem 9 | 1,890

IMPC Term

preweaning lethality, complete... 14 | 633
embryonic lethality prior to o... 5 | 148
abnormal embryo size 3 | 112
embryonic lethality prior to t... 3 | 187
pallor 3 | 13
abnormal behavior 2 | 226
abnormal lens morphology 2 | 73
abnormal skin coloration 2 | 18
embryonic growth retardation 2 | 28
increased exploration in new e... 2 | 56
abnormal QRS complex 1 | 25
abnormal embryo turning 1 | 15
abnormal foot plate morphology 1 | 2
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal skin appearance 1 | 8
abnormal tail movements 1 | 12
abnormal visceral yolk sac mor... 1 | 2
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased lactate dehydrogenas... 1 | 14
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
enlarged heart atrium 1 | 2
hyperactivity 1 | 108
hypoactivity 1 | 89
increased CD4-positive, CD25-p... 1 | 18
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
pale liver 1 | 5
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 61 | 8,484
Diabetes mellitus type 2 46 | 69
Treatment Refractory Type 2 Diabetes Mellitus 46 | 53
Multiple myeloma 39 | 1,327
Leigh disease 38 | 81
osteosarcoma 36 | 7,933
psoriasis 31 | 6,685
lung cancer 27 | 4,466
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
MITOCHONDRIAL COMPLEX I DEFICIENCY 23 | 37
glioblastoma 22 | 5,572
medulloblastoma, large-cell 20 | 6,234
astrocytic glioma 19 | 2,241
atypical teratoid / rhabdoid tumor 18 | 4,369
ependymoma 18 | 2,514
diabetes mellitus 16 | 1,663
NADH:Q(1) Oxidoreductase deficiency 15 | 20
Cancer 13 | 2,346
astrocytoma 13 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
Waldenstrons macroglobulinemia 12 | 765
Lactic acidosis 11 | 42
Leber hereditary optic neuropathy 11 | 17
oligodendroglioma 11 | 2,849
LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY 10 | 14
Obesity 10 | 616
cytochrome-c oxidase deficiency disease 10 | 14
lung adenocarcinoma 10 | 2,713
Breast cancer 9 | 3,094
Cytochrome-c Oxidase Deficiency 9 | 15
Mitochondrial myopathy 9 | 23
Optic Atrophy, Hereditary, Leber 9 | 14
Pick disease 9 | 1,893
medulloblastoma 9 | 1,524
non primary Sjogren syndrome sicca 9 | 840
acute myeloid leukemia 8 | 780
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
malignant mesothelioma 8 | 3,162
pediatric high grade glioma 8 | 2,712
ulcerative colitis 8 | 2,087
Neurodegenerative disease 7 | 383
adult high grade glioma 7 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
Anemia 6 | 252
Neoplastic Syndromes, Hereditary 6 | 48
Neuropathy 6 | 210
Paraganglioma 6 | 12
Parkinson's disease 6 | 364
Persistent generalized lymphadenopathy 6 | 15
Phaeochromocytoma 6 | 20
aldosterone-producing adenoma 6 | 664
non-small cell lung cancer 6 | 2,798
primitive neuroectodermal tumor 6 | 3,031
subependymal giant cell astrocytoma 6 | 2,287
Cardiomyopathies 5 | 90
Cerebrovascular disease 5 | 231
Hypertrophic Cardiomyopathy 5 | 56
Kidney disease 5 | 396
MELAS syndrome 5 | 17
Mitochondrial Encephalomyopathies 5 | 11
Mitochondrial complex II deficiency 5 | 5
Neurofibromatosis 5 | 37
Pneumonia 5 | 133
Rheumatoid Arthritis 5 | 1,160
Schizophrenia 5 | 501
group 4 medulloblastoma 5 | 1,875
pancreatic cancer 5 | 2,300
pituitary cancer 5 | 1,972
tuberculosis 5 | 1,557
Alzheimer's disease 4 | 644
Cardiomyopathy 4 | 110
Coronary artery disease 4 | 240
Degenerative polyarthritis 4 | 93
Gastrointestinal stromal tumor 4 | 61
Heart disease 4 | 279
Malaria 4 | 140
Osteoporosis 4 | 257
Polycystic Ovary Syndrome 4 | 332
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
cystic fibrosis 4 | 1,665
extra-adrenal pheochromocytoma 4 | 7
invasive ductal carcinoma 4 | 2,950
lung carcinoma 4 | 2,844
pilocytic astrocytoma 4 | 3,086
tuberculosis and treatment for 6 months 4 | 686
3-methylglutaconic aciduria 3 | 29
Arthritis 3 | 248
Disease Progression 3 | 125
Hypertension 3 | 287
Mitochondrial Diseases 3 | 9
Myopathy 3 | 128
Peripheral Neuropathy 3 | 303
Retinitis pigmentosa 3 | 153
Stomach Neoplasms 3 | 282
Wolff-Parkinson-White syndrome 3 | 11
acute quadriplegic myopathy 3 | 1,157
gastric carcinoma 3 | 832
hereditary spastic paraplegia 3 | 313
pancreatic carcinoma 3 | 567

Tissue

Cardiovascular System 112 | 17,958
Endocrine System 112 | 18,512
Female tissues 112 | 18,647
Liver and Pancreas 112 | 18,136
Nervous System 112 | 18,561
Skin and soft tissues 112 | 18,115
Urinary Tract 112 | 18,444
Blood and immune system 111 | 17,995
Digestive Tract 111 | 18,473
Male tissues 111 | 17,969
Respiratory system 111 | 17,484

Target Family

Enzyme 87 | 4,146
Non-IDG 22 | 11,971
Transcription Factor 2 | 1,400
Transporter 2 | 473
Kinase 1 | 634

Compartment GO Term

GO:0098803 114 | 114
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome c oxidase subunit 6A1, mitochondrial COX6A1 Tbio Enzyme -1.00384 11.8 165
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.16453 144.3 98
Cytochrome c oxidase subunit 7C, mitochondrial COX7C Tdark Enzyme -0.99133 9.67 34
Cytochrome b MT-CYB Tbio Non-IDG -3.74473 5676.0 122
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.20847 1594.9 391
Cytochrome c oxidase assembly protein COX19 COX19 Tdark Enzyme -0.94445 8.14 35
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 Tclin Enzyme -2.85403 720.1 90
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 Tclin Enzyme -2.13591 109.9 147
Cytochrome c oxidase subunit 7A1, mitochondrial COX7A1 Tbio Enzyme -1.28295 20.3 59
Cytochrome c oxidase subunit 7B, mitochondrial COX7B Tbio Enzyme -0.60140 3.69 49