Development Level

Tbio 710 | 10,625
Tchem 273 | 1,890
Tclin 240 | 602
Tdark 82 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 52 | 102
Kinase: IDG Consortium (Targets) 4 | 125

IMPC Phenotype

preweaning lethality, complete... 79 | 633
embryonic lethality prior to t... 31 | 187
embryonic lethality prior to o... 29 | 148
abnormal behavior 25 | 226
abnormal embryo size 16 | 112
decreased total body fat amoun... 16 | 186
decreased body weight 14 | 174
hyperactivity 13 | 108
preweaning lethality, incomple... 13 | 260
decreased bone mineral content 12 | 157
decreased lean body mass 12 | 195
increased circulating sodium l... 12 | 71
abnormal bone mineralization 11 | 55
decreased circulating glucose ... 11 | 121
decreased grip strength 11 | 123
increased lean body mass 11 | 107
abnormal bone structure 10 | 131
decreased circulating choleste... 10 | 85
decreased circulating triglyce... 10 | 83
decreased bone mineral density 9 | 126
increased fasted circulating g... 9 | 68
cardiovascular system phenotyp... 8 | 35
decreased mean corpuscular vol... 8 | 50
enlarged heart 8 | 111
increased bone mineral content 8 | 92
increased circulating HDL chol... 8 | 63
increased total body fat amoun... 8 | 57
abnormal gait 7 | 51
abnormal lens morphology 7 | 73
abnormal retina morphology 7 | 100
decreased circulating HDL chol... 7 | 77
decreased circulating insulin ... 7 | 75
decreased circulating serum al... 7 | 79
decreased fasted circulating g... 7 | 49
decreased prepulse inhibition 7 | 52
hypoactivity 7 | 89
increased circulating alkaline... 7 | 119
increased circulating choleste... 7 | 53
increased exploration in new e... 7 | 56
increased grip strength 7 | 83
increased mean corpuscular hem... 7 | 93
increased mean corpuscular vol... 7 | 91
abnormal QRS complex 6 | 25
decreased circulating LDL chol... 6 | 37
decreased lumbar vertebrae num... 6 | 62
increased heart weight 6 | 37
increased or absent threshold ... 6 | 128
abnormal behavioral response t... 5 | 52
abnormal epididymis morphology 5 | 31
abnormal hindbrain development 5 | 24
abnormal midbrain development 5 | 22
abnormal neural tube closure 5 | 37
abnormal sleep behavior 5 | 63
decreased blood urea nitrogen ... 5 | 31
decreased circulating alanine ... 5 | 53
decreased circulating fructosa... 5 | 31
decreased erythrocyte cell num... 5 | 43
increased blood urea nitrogen ... 5 | 44
increased circulating LDL chol... 5 | 15
increased circulating chloride... 5 | 43
increased circulating free fat... 5 | 17
prenatal lethality prior to he... 5 | 64
thrombocytopenia 5 | 46
abnormal eye morphology 4 | 38
abnormal forebrain development 4 | 18
abnormal heart morphology 4 | 51
abnormal testis morphology 4 | 30
decreased body length 4 | 108
decreased circulating alkaline... 4 | 41
decreased circulating calcium ... 4 | 33
decreased circulating total pr... 4 | 41
decreased eosinophil cell numb... 4 | 41
decreased heart rate variabili... 4 | 11
decreased leukocyte cell numbe... 4 | 54
decreased startle reflex 4 | 48
decreased total retina thickne... 4 | 20
enlarged epididymis 4 | 27
enlarged lymph nodes 4 | 27
hydrops fetalis 4 | 22
increased body weight 4 | 42
increased circulating phosphat... 4 | 24
increased circulating triglyce... 4 | 24
increased hemoglobin content 4 | 45
increased leukocyte cell numbe... 4 | 37
limb grasping 4 | 35
prenatal lethality 4 | 16
small testis 4 | 37
tremors 4 | 34
vertebral fusion 4 | 23
abnormal skin coloration 3 | 18
abnormal spleen morphology 3 | 36
decreased NK T cell number 3 | 28
decreased T cell number 3 | 31
decreased caudal vertebrae num... 3 | 49
decreased circulating bilirubi... 3 | 14
impaired glucose tolerance 3 | 52
increased erythrocyte cell num... 3 | 26
increased hematocrit 3 | 36
short tibia 3 | 82
thrombocytosis 3 | 23

Disease

ovarian cancer 672 | 8,491
psoriasis 581 | 6,685
osteosarcoma 565 | 7,933
glioblastoma 512 | 5,572
Cancer 499 | 2,346
medulloblastoma, large-cell 462 | 6,234
lung cancer 410 | 4,473
atypical teratoid / rhabdoid tumor 347 | 4,369
lung carcinoma 312 | 2,844
pilocytic astrocytoma 308 | 3,086
diabetes mellitus 282 | 1,663
Breast cancer 257 | 3,098
oligodendroglioma 254 | 2,849
pediatric high grade glioma 253 | 2,712
invasive ductal carcinoma 251 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 247 | 3,289
malignant mesothelioma 244 | 3,163
subependymal giant cell astrocytoma 236 | 2,287
lung adenocarcinoma 234 | 2,714
intraductal papillary-mucinous adenoma (IPMA) 233 | 2,956
ependymoma 224 | 2,514
non-small cell lung cancer 223 | 2,798
interstitial cystitis 222 | 2,299
Carcinoma 221 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 221 | 2,988
primitive neuroectodermal tumor 215 | 3,031
ulcerative colitis 213 | 2,087
pancreatic cancer 188 | 2,300
Multiple myeloma 185 | 1,327
astrocytic glioma 184 | 2,241
Rheumatoid Arthritis 183 | 1,170
pancreatic ductal adenocarcinoma liver metastasis 176 | 1,795
pituitary cancer 174 | 1,972
astrocytoma 172 | 1,493
Pick disease 170 | 1,893
tuberculosis 168 | 1,563
adult high grade glioma 164 | 2,148
Kidney disease 155 | 397
cystic fibrosis 151 | 1,670
Arthritis 149 | 248
group 4 medulloblastoma 149 | 1,875
posterior fossa group A ependymoma 143 | 1,511
Multiple Sclerosis 142 | 498
Alzheimer's disease 139 | 644
Hypersensitivity reaction type II disease 139 | 235
ductal carcinoma in situ 139 | 1,745
breast carcinoma 138 | 1,614
dermatomyositis 138 | 966
colon cancer 135 | 1,475
medulloblastoma 131 | 1,524
cutaneous lupus erythematosus 118 | 1,056
juvenile dermatomyositis 118 | 1,189
primary pancreatic ductal adenocarcinoma 115 | 1,271
acute quadriplegic myopathy 113 | 1,157
group 3 medulloblastoma 110 | 2,254
Obesity 109 | 616
Epilepsy 105 | 346
Heart disease 104 | 279
adrenocortical carcinoma 104 | 1,427
Schizophrenia 103 | 503
Asthma 102 | 349
Anemia 101 | 252
Hypertension 99 | 293
Vascular disease 98 | 281
Waldenstrons macroglobulinemia 97 | 764
Liver disease 95 | 219
sonic hedgehog group medulloblastoma 91 | 1,482
Mammary Neoplasms 89 | 410
Acquired immunodeficiency syndrome 86 | 164
Ankylosing spondylitis 84 | 138
Human immunodeficiency virus infectious disease 84 | 129
Atherosclerosis 83 | 275
Parkinson's disease 83 | 364
posterior fossa group B ependymoma 83 | 1,530
primary Sjogren syndrome 82 | 788
Duchenne muscular dystrophy 81 | 602
Neurodegenerative disease 79 | 383
Prostatic Neoplasms 79 | 471
Cerebrovascular disease 78 | 231
Down syndrome 78 | 548
Dermatitis 76 | 141
gastric carcinoma 75 | 832
Uveitis 74 | 103
active Crohn's disease 73 | 918
Autistic Disorder 72 | 320
Juvenile rheumatoid arthritis 70 | 105
acute myeloid leukemia 69 | 785
atypical teratoid/rhabdoid tumor 69 | 1,095
non primary Sjogren syndrome sicca 69 | 840
Lung disease 68 | 136
Inflammatory bowel disease 67 | 142
nasopharyngeal carcinoma 66 | 1,056
Intellectual disability 65 | 573
Toxic encephalopathy 65 | 131
Atopic dermatitis 64 | 944
Coronary artery disease 64 | 240
Stomach Neoplasms 64 | 282
esophageal adenocarcinoma 63 | 737
spina bifida 63 | 1,064
Hypertensive disease 62 | 193

Tissue

Nervous System 1,227 | 18,560
Endocrine System 1,225 | 18,511
Female tissues 1,224 | 18,646
Digestive Tract 1,221 | 18,472
Urinary Tract 1,221 | 18,443
Liver and Pancreas 1,217 | 18,135
Blood and immune system 1,216 | 17,994
Cardiovascular System 1,209 | 17,957
Skin and soft tissues 1,205 | 18,114
Male tissues 1,203 | 17,968
Respiratory system 1,202 | 17,483

Target Family

Non-IDG 684 | 11,969
Enzyme 257 | 4,146
Ion Channel 199 | 341
Kinase 78 | 634
Transcription Factor 33 | 1,400
Transporter 31 | 473
GPCR 18 | 408
Nuclear Receptor 3 | 48
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

Compartment GO Term

GO:0098796 1,305 | 1,305
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Short transient receptor potential channel 5 TRPC5 Tchem Ion Channel -2.22055 159.7 209
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Adaptin ear-binding coat-associated protein 2 NECAP2 Tdark Non-IDG 0.03 1.26 31
High affinity nerve growth factor receptor NTRK1 Tchem Kinase -3.03552 1003.4 1000
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91708 86.7 133
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.85874 681.4 264
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.36387 2061.0 806
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095