Development Level

Tbio 258 | 10,625
Tdark 34 | 7,003
Tchem 31 | 1,890
Tclin 1 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 145

IMPC Term

preweaning lethality, complete... 17 | 633
embryonic lethality prior to t... 10 | 187
abnormal bone structure 9 | 131
decreased circulating HDL chol... 7 | 77
decreased total body fat amoun... 7 | 186
preweaning lethality, incomple... 7 | 260
abnormal bone mineralization 6 | 55
abnormal sleep behavior 6 | 63
decreased grip strength 6 | 123
decreased lean body mass 6 | 195
increased heart weight 6 | 37
increased or absent threshold ... 6 | 128
abnormal lens morphology 5 | 73
decreased body weight 5 | 174
decreased bone mineral content 5 | 157
increased bone mineral content 5 | 92
increased circulating alkaline... 5 | 119
increased grip strength 5 | 83
increased mean corpuscular vol... 5 | 91
male infertility 5 | 62
abnormal behavior 4 | 226
abnormal limb bud morphology 4 | 15
decreased circulating LDL chol... 4 | 37
decreased circulating alanine ... 4 | 53
decreased circulating choleste... 4 | 85
decreased circulating insulin ... 4 | 75
increased lean body mass 4 | 107
increased mean corpuscular hem... 4 | 93
abnormal QRS complex 3 | 25
abnormal behavioral response t... 3 | 52
abnormal body wall morphology 3 | 7
abnormal facial morphology 3 | 9
abnormal limb morphology 3 | 7
abnormal retinal pigmentation 3 | 61
anophthalmia 3 | 20
cleft palate 3 | 6
decreased CD8-positive, alpha-... 3 | 26
decreased NK T cell number 3 | 28
decreased T cell number 3 | 31
decreased body length 3 | 108
decreased circulating triglyce... 3 | 83
decreased fasted circulating g... 3 | 49
decreased hemoglobin content 3 | 53
decreased lumbar vertebrae num... 3 | 62
decreased prepulse inhibition 3 | 52
embryonic lethality prior to o... 3 | 148
impaired glucose tolerance 3 | 52
increased bone mineral density 3 | 52
increased sacral vertebrae num... 3 | 62
polydactyly 3 | 22
abnormal craniofacial morpholo... 2 | 12
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal retina morphology 2 | 100
abnormal tail movements 2 | 12
cataract 2 | 26
decreased B cell number 2 | 30
decreased NK cell number 2 | 16
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating calcium ... 2 | 33
decreased circulating potassiu... 2 | 17
decreased circulating serum al... 2 | 79
decreased erythrocyte cell num... 2 | 43
decreased gamma-delta T cell n... 2 | 18
decreased heart weight 2 | 44
decreased mean corpuscular hem... 2 | 34
decreased monocyte cell number 2 | 28
decreased respiratory quotient 2 | 12
decreased rib number 2 | 59
decreased startle reflex 2 | 48
decreased vertical activity 2 | 22
edema 2 | 11
enlarged epididymis 2 | 27
enlarged heart 2 | 111
facial cleft 2 | 3
hyperactivity 2 | 108
hypoactivity 2 | 89
immune system phenotype 2 | 17
increased blood urea nitrogen ... 2 | 44
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 26
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 25
increased prepulse inhibition 2 | 21
increased startle reflex 2 | 38
limb grasping 2 | 35
premature death 2 | 5
straub tail 2 | 26
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal neural tube closure 1 | 37
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
embryonic growth retardation 1 | 28
female infertility 1 | 34
increased CD5-positive Ly6C-po... 1 | 4
increased circulating magnesiu... 1 | 10

Disease

ovarian cancer 197 | 8,492
osteosarcoma 167 | 7,933
psoriasis 136 | 6,685
medulloblastoma, large-cell 134 | 6,234
glioblastoma 122 | 5,572
atypical teratoid / rhabdoid tumor 90 | 4,369
lung cancer 90 | 4,473
intraductal papillary-mucinous adenoma (IPMA) 73 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 72 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 72 | 3,289
pilocytic astrocytoma 68 | 3,086
Breast cancer 64 | 3,099
malignant mesothelioma 64 | 3,163
invasive ductal carcinoma 59 | 2,950
lung carcinoma 58 | 2,844
pancreatic cancer 58 | 2,300
ependymoma 53 | 2,514
pediatric high grade glioma 51 | 2,712
group 4 medulloblastoma 50 | 1,875
oligodendroglioma 50 | 2,849
subependymal giant cell astrocytoma 49 | 2,287
adult high grade glioma 48 | 2,148
lung adenocarcinoma 48 | 2,714
astrocytic glioma 47 | 2,241
Carcinoma 46 | 2,147
Pick disease 45 | 1,893
astrocytoma 44 | 1,493
primitive neuroectodermal tumor 44 | 3,031
interstitial cystitis 43 | 2,299
non-small cell lung cancer 43 | 2,798
Cancer 40 | 2,346
diabetes mellitus 39 | 1,663
cystic fibrosis 37 | 1,670
ductal carcinoma in situ 37 | 1,745
pituitary cancer 37 | 1,972
Multiple myeloma 36 | 1,328
breast carcinoma 36 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,795
ulcerative colitis 35 | 2,087
tuberculosis 34 | 1,563
Alzheimer's disease 30 | 644
primary pancreatic ductal adenocarcinoma 30 | 1,271
juvenile dermatomyositis 29 | 1,189
colon cancer 28 | 1,475
group 3 medulloblastoma 28 | 2,254
acute quadriplegic myopathy 27 | 1,157
medulloblastoma 27 | 1,524
posterior fossa group A ependymoma 27 | 1,511
posterior fossa group B ependymoma 27 | 1,530
dermatomyositis 26 | 967
Rheumatoid Arthritis 25 | 1,171
Waldenstrons macroglobulinemia 25 | 765
tuberculosis and treatment for 6 months 25 | 686
atypical teratoid/rhabdoid tumor 24 | 1,095
spina bifida 22 | 1,064
Neurodegenerative disease 21 | 383
active Crohn's disease 21 | 918
adrenocortical carcinoma 21 | 1,427
Duchenne muscular dystrophy 20 | 602
acute myeloid leukemia 19 | 785
primary Sjogren syndrome 19 | 789
Down syndrome 18 | 548
Intellectual disability 18 | 573
gastric carcinoma 18 | 832
aldosterone-producing adenoma 17 | 664
esophageal adenocarcinoma 16 | 737
hereditary spastic paraplegia 16 | 313
nasopharyngeal carcinoma 16 | 1,056
non primary Sjogren syndrome sicca 16 | 840
progressive supranuclear palsy 16 | 674
sonic hedgehog group medulloblastoma 16 | 1,482
active ulcerative colitis 15 | 477
cutaneous lupus erythematosus 15 | 1,056
pancreatic carcinoma 15 | 567
IGA Glomerulonephritis 13 | 454
mucosa-associated lymphoid tissue lymphoma 13 | 480
Atopic dermatitis 12 | 944
Kidney disease 12 | 397
Multiple Sclerosis 12 | 498
Polycystic Ovary Syndrome 12 | 335
Prostatic Neoplasms 12 | 471
Amyotrophic Lateral Sclerosis 11 | 432
Obesity 11 | 616
sarcoidosis 11 | 368
Congenital disorder of glycosylation 10 | 53
Adenoma 9 | 165
Becker muscular dystrophy 9 | 187
Gaucher disease type 1 9 | 171
Parkinson's disease 9 | 364
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
chronic lymphocytic leukemia 9 | 244
Liver disease 8 | 219
Mammary Neoplasms 8 | 410
Microcephaly 8 | 149
Oculocerebrorenal syndrome 8 | 24
Schizophrenia 8 | 503
gastric cancer 8 | 436
head and neck cancer and chronic obstructive pulmonary disease 8 | 237
fibroadenoma 7 | 557
hepatocellular carcinoma 7 | 550

Tissue

Nervous System 317 | 18,561
Endocrine System 316 | 18,512
Cardiovascular System 315 | 17,958
Digestive Tract 315 | 18,473
Female tissues 315 | 18,647
Male tissues 315 | 17,969
Urinary Tract 315 | 18,444
Blood and immune system 314 | 17,995
Liver and Pancreas 314 | 18,136
Respiratory system 314 | 17,484
Skin and soft tissues 310 | 18,115

Target Family

Non-IDG 195 | 11,969
Enzyme 108 | 4,146
Transporter 9 | 473
Kinase 6 | 634
GPCR 4 | 408
Ion Channel 2 | 341

Compartment GO Term

GO:0098791 324 | 324
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.16287 147.6 149
Protein dopey-2 DOPEY2 Tbio Non-IDG -0.67912 6.04 14
Soluble calcium-activated nucleotidase 1 CANT1 Tbio Enzyme -1.42022 25.3 175
Protein chibby homolog 1 CBY1 Tbio Non-IDG -2.28288 192.4 61
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.85200 7.21 86
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.46179 31.8 115
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ARAP1 Tbio Non-IDG -0.97819 13.6 86
Vacuolar protein sorting-associated protein 51 homolog VPS51 Tdark Non-IDG -2.57063 363.8 49
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274
Conserved oligomeric Golgi complex subunit 1 COG1 Tbio Non-IDG -1.66863 43.0 81