Development Level

Tbio 66 | 11,651
Tdark 15 | 6,593
Tchem 4 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 12 | 979
decreased leukocyte cell numbe... 2 | 73
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
increased fasted circulating g... 2 | 76
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal neural tube morpholog... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
male infertility 1 | 123
thrombocytosis 1 | 27

Disease

ovarian cancer 59 | 8,520
Carcinoma 52 | 11,493
medulloblastoma, large-cell 35 | 6,241
osteosarcoma 34 | 7,950
glioblastoma 33 | 5,792
lung cancer 33 | 4,740
group 3 medulloblastoma 32 | 4,104
psoriasis 32 | 6,694
ependymoma 24 | 4,679
atypical teratoid / rhabdoid tumor 23 | 5,112
Multiple myeloma 21 | 1,332
oligodendroglioma 21 | 2,850
dermatomyositis 19 | 966
malignant mesothelioma 19 | 3,232
primitive neuroectodermal tumor 17 | 3,035
Kidney cancer 16 | 2,613
astrocytoma 16 | 1,146
diabetes mellitus 16 | 1,728
Waldenstrons macroglobulinemia 14 | 765
Pick disease 13 | 1,894
acute quadriplegic myopathy 13 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
astrocytic glioma 12 | 2,597
lung adenocarcinoma 12 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Intellectual disability 11 | 1,016
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
Conductive hearing loss 10 | 123
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
progressive supranuclear palsy 10 | 676
Breast cancer 9 | 3,578
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Retinitis Pigmentosa 8 | 226
juvenile dermatomyositis 8 | 1,187
Anteverted nostril 7 | 191
Glaucoma 7 | 239
acute myeloid leukemia 7 | 783
subependymal giant cell astrocytoma 7 | 2,287
Abnormality of retinal pigmentation 6 | 111
Abnormality of the retinal vasculature 6 | 59
Atypical scarring of skin 6 | 62
Blind Vision 6 | 111
Blindness, Legal 6 | 110
Broad flat nasal bridge 6 | 236
Cancer 6 | 2,499
Cataract 6 | 297
Congenital anomaly of testis 6 | 52
Congenital hypoplasia of penis 6 | 176
Electroretinogram abnormal 6 | 95
Gaucher disease type 1 6 | 180
Hyperinsulinism 6 | 133
Hypogonadism 6 | 173
Keratoconus 6 | 113
Lens Opacities 6 | 231
Nasal bridge wide 6 | 236
Night blindness, progressive 6 | 51
Nystagmus 6 | 317
Obesity 6 | 678
Ophthalmoplegia 6 | 106
Optic Atrophy 6 | 242
Photodysphoria 6 | 121
Photophobia 6 | 121
Retinal pigment epithelial abnormality 6 | 111
Sensorineural Hearing Loss (disorder) 6 | 284
group 4 medulloblastoma 6 | 1,855
pituitary cancer 6 | 1,972
relapsing-remitting multiple sclerosis 6 | 18
Amyotrophic lateral sclerosis 5 | 451
Difficulties with night vision 5 | 87
HIV Infections 5 | 102
Night Blindness 5 | 101
breast carcinoma 5 | 1,638
non primary Sjogren syndrome sicca 5 | 891
sonic hedgehog group medulloblastoma 5 | 467
Animal Mammary Neoplasms 4 | 136
Autosomal recessive predisposition 4 | 1,442
Cleft Palate 4 | 271
Hypoplastic mandible condyle 4 | 275
Immune system cancer 4 | 140
Mammary Neoplasms, Animal 4 | 136
Mammary Neoplasms, Experimental 4 | 154
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Mixed connective tissue disease 4 | 16
Neuronal ceroid lipofuscinosis 1 4 | 15
Rheumatoid arthritis 4 | 1,191
Uranostaphyloschisis 4 | 167
aldosterone-producing adenoma 4 | 665
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
pediatric high grade glioma 4 | 1,064
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
spina bifida 3 | 1,074

Tissue

Digestive Tract 84 | 17,369
Endocrine System 84 | 18,159
Female tissues 84 | 17,400
Liver and Pancreas 84 | 16,750
Male tissues 84 | 17,142
Nervous System 84 | 16,725
Respiratory system 84 | 16,393
Urinary Tract 84 | 16,678
Blood and immune system 83 | 16,909
Cardiovascular System 83 | 15,192
Skin and soft tissues 83 | 17,230

Target Family

Non-IDG 74 | 12,091
Enzyme 9 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

Compartment GO Term

GO:0097525 85 | 85
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleolysin TIA-1 isoform p40 TIA1 Tbio Non-IDG -2.86461 714.2 314
U6 snRNA-associated Sm-like protein LSm5 LSM5 Tdark Non-IDG -0.98876 8.80 46
Probable ATP-dependent RNA helicase DDX23 DDX23 Tbio Enzyme -1.24669 18.6 167
U4/U6 small nuclear ribonucleoprotein Prp31 PRPF31 Tbio Non-IDG -1.84397 72.4 216
Thioredoxin-like protein 4B TXNL4B Tbio Non-IDG -2.20773 154.6 44
Putative small nuclear ribonucleoprotein G-like protein 15 SNRPGP15 Tdark Non-IDG 0.12 1.33 0
Heterogeneous nuclear ribonucleoprotein H HNRNPH1 Tbio Non-IDG -1.71562 50.9 205
U4/U6 small nuclear ribonucleoprotein Prp3 PRPF3 Tbio Non-IDG -1.73686 54.3 123
RNA-binding protein with multiple splicing RBPMS Tbio Non-IDG -2.12771 131.9 266
Small nuclear ribonucleoprotein-associated protein N SNURF Tbio Non-IDG -1.65159 45.0 119