Development Level

Tbio 56 | 10,625
Tdark 16 | 7,003
Tchem 6 | 1,890

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 633
decreased leukocyte cell numbe... 2 | 54
decreased neutrophil cell numb... 2 | 37
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased fasted circulating g... 2 | 68
thrombocytosis 2 | 23
abnormal behavior 1 | 226
abnormal neural tube morpholog... 1 | 8
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased grip strength 1 | 123
decreased lymphocyte cell numb... 1 | 9
decreased monocyte cell number 1 | 28
enlarged heart 1 | 111
hyperactivity 1 | 108
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
sparse hair 1 | 6

Disease

ovarian cancer 56 | 8,491
medulloblastoma, large-cell 32 | 6,234
osteosarcoma 31 | 7,933
glioblastoma 29 | 5,572
lung cancer 29 | 4,473
psoriasis 29 | 6,685
ependymoma 22 | 2,514
Multiple myeloma 21 | 1,327
group 3 medulloblastoma 21 | 2,254
oligodendroglioma 21 | 2,849
astrocytoma 19 | 1,493
atypical teratoid / rhabdoid tumor 18 | 4,369
dermatomyositis 18 | 966
diabetes mellitus 16 | 1,663
primitive neuroectodermal tumor 16 | 3,031
malignant mesothelioma 15 | 3,163
Waldenstrons macroglobulinemia 13 | 764
Pick disease 12 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
sonic hedgehog group medulloblastoma 12 | 1,482
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
acute quadriplegic myopathy 10 | 1,157
lung adenocarcinoma 10 | 2,714
progressive supranuclear palsy 10 | 674
Carcinoma 9 | 2,147
astrocytic glioma 9 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
pediatric high grade glioma 9 | 2,712
Retinitis pigmentosa 8 | 156
acute myeloid leukemia 7 | 785
atypical teratoid/rhabdoid tumor 7 | 1,095
juvenile dermatomyositis 7 | 1,189
Breast cancer 6 | 3,098
Cancer 6 | 2,346
Gaucher disease type 1 6 | 171
adult high grade glioma 6 | 2,148
group 4 medulloblastoma 6 | 1,875
HIV Infections 5 | 99
Intellectual disability 5 | 573
Lupus erythematosus 5 | 80
breast carcinoma 5 | 1,614
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic Lateral Sclerosis 4 | 432
Animal Mammary Neoplasms 4 | 135
Immune system cancer 4 | 38
Mammary Neoplasms, Experimental 4 | 149
Mixed connective tissue disease 4 | 16
Rheumatoid Arthritis 4 | 1,170
aldosterone-producing adenoma 4 | 664
non primary Sjogren syndrome sicca 4 | 840
pancreatic cancer 4 | 2,300
relapsing-remitting multiple sclerosis 4 | 18
Hematologic cancer 3 | 9
Nager acrofacial dysostosis 3 | 21
Treacher Collins syndrome 3 | 29
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
glioblastoma multiforme 3 | 347
invasive ductal carcinoma 3 | 2,950
nasopharyngeal carcinoma 3 | 1,056
non-small cell lung cancer 3 | 2,798
tuberculosis 3 | 1,563
tuberculosis and treatment for 6 months 3 | 686
Atopic dermatitis 2 | 944
Choanal atresia 2 | 19
Chronic obstructive pulmonary disease 2 | 147
Congenital myasthenic syndrome 2 | 28
Crohn's disease 2 | 304
Epilepsy 2 | 346
Keratosis 2 | 34
MYELODYSPLASTIC SYNDROME 2 | 39
Melanoma 2 | 261
Microcephaly 2 | 149
Muscular atrophy 2 | 67
Night Blindness 2 | 39
Pityriasis rubra pilaris 2 | 5
Pneumonia 2 | 133
Polycystic Ovary Syndrome 2 | 334
Radioulnar synostosis 2 | 13
Spinal muscular atrophy 2 | 24
Subcutaneous panniculitis-like T-cell lymphoma 2 | 16
adrenocortical carcinoma 2 | 1,427
colon cancer 2 | 1,475
hereditary spastic paraplegia 2 | 313
interstitial lung disease 2 | 292
medulloblastoma 2 | 1,524
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
spina bifida 2 | 1,064
Agoraphobia 1 | 16
Cavernous hemangioma 1 | 12
Coloboma 1 | 52
Cone dystrophy 1 | 59
Esophageal atresia 1 | 25
Prevention of Cardiac Transplant Rejection 1 | 14
Silver-Russell syndrome 1 | 37
Skin disease 1 | 65
Spinocerebellar ataxia type 1 1 | 16
Systemic scleroderma 1 | 66

Tissue

Blood and immune system 76 | 17,994
Cardiovascular System 76 | 17,957
Digestive Tract 76 | 18,472
Endocrine System 76 | 18,511
Female tissues 76 | 18,646
Liver and Pancreas 76 | 18,135
Male tissues 76 | 17,968
Nervous System 76 | 18,560
Respiratory system 76 | 17,483
Skin and soft tissues 76 | 18,114
Urinary Tract 76 | 18,443

Target Family

Non-IDG 70 | 11,969
Enzyme 5 | 4,146
Epigenetic 2 | 242
Kinase 1 | 634

Compartment GO Term

GO:0097525 78 | 78
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U4/U6 small nuclear ribonucleoprotein Prp4 PRPF4 Tchem Non-IDG -0.55879 7.56 79
Small nuclear ribonucleoprotein-associated protein N SNURF Tbio Non-IDG -1.63847 44.6 100
Pre-mRNA-processing factor 6 PRPF6 Tbio Non-IDG -1.35844 27.6 163
Peptidyl-prolyl cis-trans isomerase H PPIH Tbio Enzyme -1.31939 21.7 63
U4/U6 small nuclear ribonucleoprotein Prp3 PRPF3 Tbio Non-IDG -1.71435 998.6 107
Splicing factor 3B subunit 5 SF3B5 Tdark Non-IDG -0.13276 1.30 17
U4/U6.U5 tri-snRNP-associated protein 1 SART1 Tbio Non-IDG -1.81163 66.1 137
Splicing factor 1 SF1 Tbio Non-IDG -1.65913 45.1 258
Pre-mRNA-splicing factor SLU7 SLU7 Tbio Non-IDG -1.30438 19.3 179
Putative RNA-binding protein Luc7-like 1 LUC7L Tbio Non-IDG -1.01264 9.66 142