Development Level

Tbio 102 | 11,445
Tchem 16 | 1,598
Tdark 4 | 6,588
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to t... 6 | 278
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to o... 5 | 239
decreased lymphocyte cell numb... 4 | 83
abnormal retina morphology 3 | 71
abnormal seminal vesicle morph... 3 | 114
decreased vertical activity 3 | 208
increased bone mineral density 3 | 72
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
abnormal craniofacial morpholo... 2 | 33
abnormal embryo size 2 | 220
abnormal head morphology 2 | 10
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal neural tube closure 2 | 46
abnormal startle reflex 2 | 15
decreased caudal vertebrae num... 2 | 53
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
hydrometra 2 | 53
increased bone mineral content 2 | 108
increased circulating potassiu... 2 | 29
increased neutrophil cell numb... 2 | 46
mammalian phenotype 2 | 17
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal tooth morphology 1 | 24
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased prepulse inhibition 1 | 82
dilated heart left ventricle 1 | 11
edema 1 | 59
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
microphthalmia 1 | 26
short tibia 1 | 97

Disease

Carcinoma 72 | 11,493
osteosarcoma 70 | 7,950
ovarian cancer 69 | 8,520
psoriasis 52 | 6,694
Cancer 51 | 2,499
glioblastoma 45 | 5,792
lung cancer 45 | 4,740
medulloblastoma, large-cell 41 | 6,241
malignant mesothelioma 34 | 3,232
group 3 medulloblastoma 31 | 4,104
atypical teratoid / rhabdoid tumor 30 | 5,112
ependymoma 30 | 4,679
Breast cancer 26 | 3,578
primitive neuroectodermal tumor 26 | 3,035
diabetes mellitus 22 | 1,728
oligodendroglioma 22 | 2,850
pancreatic cancer 21 | 2,398
adult high grade glioma 20 | 3,801
astrocytic glioma 20 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
invasive ductal carcinoma 19 | 2,951
pituitary cancer 19 | 1,972
group 4 medulloblastoma 18 | 1,855
lung adenocarcinoma 18 | 2,716
lung carcinoma 18 | 2,843
Kidney cancer 17 | 2,613
subependymal giant cell astrocytoma 17 | 2,287
Intellectual disability 16 | 1,016
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
non-small cell lung cancer 16 | 2,890
ulcerative colitis 16 | 1,819
Pick disease 15 | 1,894
astrocytoma 15 | 1,146
ductal carcinoma in situ 15 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
Schizophrenia 14 | 1,160
breast carcinoma 14 | 1,638
colon cancer 14 | 1,478
tuberculosis 14 | 2,010
Breast Neoplasms 13 | 445
Multiple myeloma 13 | 1,332
Obesity 13 | 678
acute quadriplegic myopathy 13 | 1,158
dermatomyositis 13 | 966
Rheumatoid arthritis 12 | 1,191
acute myeloid leukemia 12 | 783
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
primary pancreatic ductal adenocarcinoma 12 | 1,109
Astrocytoma, Pilocytic 11 | 3,081
Cockayne syndrome 11 | 60
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mammary Neoplasms 11 | 425
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Photosensitive trichothiodystrophy 11 | 30
Poor school performance 11 | 645
interstitial cystitis 11 | 2,312
Melanoma 10 | 711
Osteoporosis 10 | 363
Polycystic ovary syndrome 10 | 360
Waldenstrons macroglobulinemia 10 | 765
Xeroderma pigmentosum group B 10 | 20
juvenile dermatomyositis 10 | 1,187
pediatric high grade glioma 10 | 1,064
Autosomal recessive predisposition 9 | 1,442
Epilepsy 9 | 792
Kidney disease 9 | 430
Liver carcinoma 9 | 240
Small head 9 | 374
Alzheimer's disease 8 | 658
Bipolar Disorder 8 | 666
Carcinoma, Hepatocellular 8 | 228
Cryptorchidism 8 | 296
Seizures 8 | 596
Short stature 8 | 531
Vascular disease 8 | 319
adrenocortical carcinoma 8 | 1,428
aldosterone-producing adenoma 8 | 665
cystic fibrosis 8 | 1,696
gastric carcinoma 8 | 807
non primary Sjogren syndrome sicca 8 | 891
Acquired metabolic disease 7 | 336
Arthritis, Juvenile 7 | 126
Colonic Neoplasms 7 | 142
Colorectal Neoplasms 7 | 243
Juvenile arthritis 7 | 126
Lung Neoplasms 7 | 232
Multiple Sclerosis 7 | 540
Muscle hypotonia 7 | 571
Pancreatic Neoplasm 7 | 85
Pancreatic Neoplasms 7 | 85
Parkinson's disease 7 | 392
Prostatic Neoplasms 7 | 495
Stomach Neoplasms 7 | 300
Strabismus 7 | 270
chronic lymphosyte leukemia 7 | 204
hepatocellular carcinoma 7 | 547
Cognitive delay 6 | 608
Mental and motor retardation 6 | 608

Tissue

Digestive Tract 121 | 17,369
Endocrine System 121 | 18,159
Male tissues 121 | 17,142
Blood and immune system 120 | 16,909
Female tissues 120 | 17,400
Skin and soft tissues 120 | 17,230
Liver and Pancreas 117 | 16,750
Urinary Tract 117 | 16,678
Nervous System 116 | 16,725
Respiratory system 116 | 16,393
Cardiovascular System 113 | 15,192

Target Family

Non-IDG 49 | 12,091
Transcription Factor 48 | 1,400
Enzyme 12 | 4,145
Epigenetic 6 | 242
Nuclear Receptor 6 | 48
Kinase 4 | 634

Compartment GO Term

GO:0090575 125 | 125
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Achaete-scute homolog 4 ASCL4 Tdark Transcription Factor -0.31083 1.97 22
Mediator of RNA polymerase II transcription subunit 31 MED31 Tbio Enzyme -1.19048 15.1 61
Heterogeneous nuclear ribonucleoprotein A/B HNRNPAB Tbio Non-IDG -1.15839 12.5 96
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.18859 223.1 91
Transcription initiation factor TFIID subunit 9B TAF9B Tbio Non-IDG -1.38372 23.5 105
LIM domain-binding protein 1 LDB1 Tbio Non-IDG -2.22623 164.4 206
Max-interacting protein 1 MXI1 Tbio Transcription Factor -2.03408 107.7 179
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
TFIIA-alpha and beta-like factor GTF2A1L Tbio Non-IDG -0.66901 3.86 222
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -1.32757 20.2 148