Development Level

Tbio 666 | 10,625
Tdark 218 | 7,003
Tchem 123 | 1,890
Tclin 86 | 602

Collection

Eligible Kinase Proteins 4 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 63 | 633
embryonic lethality prior to o... 23 | 148
embryonic lethality prior to t... 19 | 187
abnormal behavior 17 | 226
decreased body weight 17 | 174
preweaning lethality, incomple... 17 | 260
decreased lean body mass 13 | 195
decreased bone mineral content 12 | 157
decreased grip strength 11 | 123
decreased circulating glucose ... 10 | 121
hypoactivity 10 | 89
abnormal bone structure 9 | 131
decreased circulating choleste... 9 | 85
decreased total body fat amoun... 9 | 186
increased lean body mass 9 | 107
increased mean corpuscular hem... 9 | 93
abnormal embryo size 8 | 112
increased grip strength 8 | 83
abnormal lens morphology 7 | 73
decreased circulating HDL chol... 7 | 77
decreased rib number 7 | 59
increased circulating alkaline... 7 | 119
increased circulating sodium l... 7 | 71
increased mean corpuscular vol... 7 | 91
abnormal retina morphology 6 | 100
decreased body length 6 | 108
decreased leukocyte cell numbe... 6 | 54
enlarged heart 6 | 111
increased circulating choleste... 6 | 53
increased circulating phosphat... 6 | 24
increased heart weight 6 | 37
increased or absent threshold ... 6 | 128
prenatal lethality prior to he... 6 | 64
abnormal snout morphology 5 | 18
decreased caudal vertebrae num... 5 | 49
decreased circulating alkaline... 5 | 41
decreased circulating insulin ... 5 | 75
decreased heart weight 5 | 44
decreased lumbar vertebrae num... 5 | 62
decreased total retina thickne... 5 | 20
embryonic growth retardation 5 | 28
hyperactivity 5 | 108
increased blood urea nitrogen ... 5 | 44
increased sacral vertebrae num... 5 | 62
short tibia 5 | 82
thrombocytopenia 5 | 46
abnormal bone mineralization 4 | 55
abnormal locomotor activation 4 | 26
abnormal skin morphology 4 | 23
decreased circulating LDL chol... 4 | 37
decreased circulating serum al... 4 | 79
decreased circulating triglyce... 4 | 83
decreased mean corpuscular vol... 4 | 50
increased circulating HDL chol... 4 | 63
increased circulating creatini... 4 | 29
increased exploration in new e... 4 | 56
increased fasted circulating g... 4 | 68
increased total body fat amoun... 4 | 57
male infertility 4 | 62
abnormal clavicle morphology 3 | 5
abnormal femur morphology 3 | 14
abnormal heart left ventricle ... 3 | 20
abnormal heart morphology 3 | 51
abnormal limb bud morphology 3 | 15
abnormal neural tube closure 3 | 37
abnormal rib morphology 3 | 28
abnormal sleep behavior 3 | 63
abnormal tibia morphology 3 | 14
abnormal tooth morphology 3 | 24
decreased blood urea nitrogen ... 3 | 31
decreased bone mineral density 3 | 126
decreased circulating aspartat... 3 | 27
decreased circulating creatini... 3 | 31
decreased circulating glycerol... 3 | 19
decreased circulating iron lev... 3 | 25
decreased circulating total pr... 3 | 41
decreased fasted circulating g... 3 | 49
decreased hematocrit 3 | 25
decreased mean corpuscular hem... 3 | 34
decreased mean platelet volume 3 | 12
decreased startle reflex 3 | 48
female infertility 3 | 34
impaired glucose tolerance 3 | 52
improved glucose tolerance 3 | 56
increased bone mineral content 3 | 92
increased circulating aspartat... 3 | 17
increased startle reflex 3 | 38
pallor 3 | 13
persistence of hyaloid vascula... 3 | 22
small thymus 3 | 11
tremors 3 | 34
decreased circulating calcium ... 2 | 33
decreased hemoglobin content 2 | 53
increased body weight 2 | 42
increased circulating bilirubi... 2 | 16
increased circulating calcium ... 2 | 32
increased circulating chloride... 2 | 43
increased circulating potassiu... 2 | 31
increased erythrocyte cell num... 2 | 26
increased respiratory quotient 2 | 12

Disease

ovarian cancer 593 | 8,484
osteosarcoma 492 | 7,933
medulloblastoma, large-cell 372 | 6,234
psoriasis 359 | 6,685
lung cancer 345 | 4,466
glioblastoma 318 | 5,572
atypical teratoid / rhabdoid tumor 242 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 200 | 3,289
Breast cancer 196 | 3,094
pancreatic ductal adenocarcinoma liver metastasis 186 | 1,795
malignant mesothelioma 185 | 3,162
Cancer 178 | 2,346
Multiple myeloma 174 | 1,327
invasive ductal carcinoma 171 | 2,950
non-small cell lung cancer 170 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 167 | 2,988
pediatric high grade glioma 164 | 2,712
oligodendroglioma 157 | 2,849
ependymoma 156 | 2,514
primitive neuroectodermal tumor 156 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 150 | 2,956
lung adenocarcinoma 146 | 2,713
astrocytic glioma 144 | 2,241
group 3 medulloblastoma 144 | 2,254
pilocytic astrocytoma 137 | 3,086
pancreatic cancer 126 | 2,300
Pick disease 125 | 1,893
lung carcinoma 124 | 2,844
subependymal giant cell astrocytoma 112 | 2,287
ulcerative colitis 112 | 2,087
diabetes mellitus 111 | 1,663
adult high grade glioma 104 | 2,148
breast carcinoma 101 | 1,614
group 4 medulloblastoma 101 | 1,875
ductal carcinoma in situ 93 | 1,745
astrocytoma 89 | 1,493
interstitial cystitis 89 | 2,299
colon cancer 86 | 1,475
medulloblastoma 86 | 1,524
tuberculosis 85 | 1,557
Rheumatoid Arthritis 83 | 1,160
pituitary cancer 81 | 1,972
non primary Sjogren syndrome sicca 80 | 840
Waldenstrons macroglobulinemia 79 | 765
acute quadriplegic myopathy 79 | 1,157
dermatomyositis 79 | 933
adrenocortical carcinoma 78 | 1,427
cystic fibrosis 77 | 1,665
Carcinoma 76 | 2,147
Alzheimer's disease 75 | 644
Neurodegenerative disease 74 | 383
acute myeloid leukemia 73 | 780
posterior fossa group A ependymoma 72 | 1,511
sonic hedgehog group medulloblastoma 72 | 1,482
primary pancreatic ductal adenocarcinoma 71 | 1,271
nasopharyngeal carcinoma 65 | 1,056
atypical teratoid/rhabdoid tumor 63 | 1,095
juvenile dermatomyositis 63 | 1,189
posterior fossa group B ependymoma 62 | 1,530
Obesity 61 | 616
Parkinson's disease 58 | 364
aldosterone-producing adenoma 58 | 664
Mammary Neoplasms 54 | 410
cutaneous lupus erythematosus 54 | 1,056
Diabetes mellitus type 2 52 | 69
Treatment Refractory Type 2 Diabetes Mellitus 51 | 53
tuberculosis and treatment for 6 months 47 | 686
Atopic dermatitis 46 | 944
Leigh disease 46 | 81
Vascular disease 44 | 281
primary Sjogren syndrome 44 | 789
Kidney disease 43 | 396
Toxic encephalopathy 43 | 131
Down syndrome 42 | 548
hereditary spastic paraplegia 42 | 313
Amyotrophic Lateral Sclerosis 41 | 431
gastric carcinoma 41 | 832
progressive supranuclear palsy 40 | 674
Schizophrenia 39 | 501
esophageal adenocarcinoma 39 | 737
spina bifida 38 | 1,064
Prostatic Neoplasms 36 | 471
Stomach Neoplasms 36 | 282
active Crohn's disease 36 | 918
pancreatic carcinoma 35 | 567
IGA Glomerulonephritis 33 | 454
MITOCHONDRIAL COMPLEX I DEFICIENCY 32 | 37
hepatocellular carcinoma 32 | 532
Atherosclerosis 31 | 275
Diabetes Mellitus, Experimental 31 | 106
Heart disease 31 | 279
Multiple Sclerosis 31 | 498
Neuropathy 31 | 210
Duchenne muscular dystrophy 30 | 602
Endometriosis 30 | 535
Brain disease 29 | 83
Liver carcinoma 29 | 217
Polycystic Ovary Syndrome 29 | 332
Asthma 28 | 349
Epilepsy 28 | 346

Tissue

Nervous System 1,079 | 18,561
Female tissues 1,078 | 18,647
Male tissues 1,078 | 17,969
Blood and immune system 1,077 | 17,995
Urinary Tract 1,077 | 18,444
Liver and Pancreas 1,076 | 18,136
Digestive Tract 1,075 | 18,473
Endocrine System 1,075 | 18,512
Cardiovascular System 1,073 | 17,958
Skin and soft tissues 1,065 | 18,115
Respiratory system 1,063 | 17,484

Target Family

Non-IDG 556 | 11,971
Enzyme 362 | 4,146
Transporter 71 | 473
Kinase 40 | 634
Transcription Factor 27 | 1,400
Ion Channel 16 | 341
Epigenetic 9 | 242
GPCR 8 | 406
Nuclear Receptor 3 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

GO:0031975 1,093 | 1,093
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial 2-oxodicarboxylate carrier SLC25A21 Tbio Transporter -0.46900 2.68 102
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Cardiac phospholamban PLN Tbio Non-IDG -1.89899 84.7 326
Testis-specific gene 10 protein TSGA10 Tbio Non-IDG -1.05563 13.1 82