Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal retina morphology 1 | 71
decreased KLRG1+ CD4 alpha bet... 1 | 5
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased anti-nuclear antigen... 1 | 19
increased circulating potassiu... 1 | 29

Disease

Cockayne syndrome 8 | 60
Photosensitive trichothiodystrophy 8 | 30
Carcinoma 6 | 11,493
Xeroderma pigmentosum 6 | 43
ovarian cancer 6 | 8,520
Xeroderma pigmentosum group B 5 | 20
Pick disease 4 | 1,894
Xeroderma pigmentosum group D 4 | 33
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
Cancer 3 | 2,499
Xeroderma pigmentosum group G 3 | 16
Abnormally small eyeball 2 | 97
Arteriosclerosis 2 | 11
Arthralgia 2 | 90
Atrophic condition of skin 2 | 25
Autosomal recessive predisposition 2 | 1,442
Basal cell carcinoma 2 | 54
Basal cell nevi 2 | 23
Brittle hair 2 | 25
Cachexia 2 | 50
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Congenital Nonbullous Ichthyosiform Erythroderma 2 | 16
Congenital deafness 2 | 185
Conjunctival telangiectasis 2 | 14
Cryptorchidism 2 | 296
Deafness 2 | 198
Decreased size of eyeball 2 | 97
Dental abnormalities 2 | 60
Developmental regression 2 | 95
Dry skin 2 | 75
Dull intelligence 2 | 645
Electroencephalogram abnormal 2 | 101
Erythema 2 | 58
Failure to gain weight 2 | 365
Fatigue 2 | 182
Fever 2 | 138
Flushing 2 | 60
Fractured hair 2 | 25
Fragile hair 2 | 25
Freckles 2 | 33
Hardened artery wall 2 | 6
Hearing Loss, Partial 2 | 185
Hydrocephalus 2 | 152
Hyperkeratosis 2 | 50
Hyperpigmented macules 2 | 42
Hypogonadism 2 | 173
Impaired cognition 2 | 96
Intellectual disability 2 | 1,016
Keratitis 2 | 62
Lens Opacities 2 | 231
Loss of developmental milestones 2 | 95
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Mental deterioration in childhood 2 | 95
Mental impairment 2 | 95
Microphthalmos 2 | 100
Muscle Spasticity 2 | 195
Neurodevelopmental regression 2 | 95
Numerous pigmented freckles 2 | 4
Optic Atrophy 2 | 242
Papilloma 2 | 44
Pediatric failure to thrive 2 | 365
Peripheral demyelinating neuropathy 2 | 7
Photosensitivity of skin 2 | 51
Poikiloderma 2 | 14
Poor school performance 2 | 645
Precociously senile appearance 2 | 18
Progressive mental retardation 2 | 37
Psychomotor regression 2 | 95
Psychomotor regression beginning in infancy 2 | 95
Psychomotor regression in infants 2 | 95
Psychomotor regression, progressive 2 | 95
Reduced tensile strength of hair 2 | 25
Retinal Diseases 2 | 55
Sensorineural Hearing Loss (disorder) 2 | 284
Short stature 2 | 531
Small head 2 | 374
Squamous cell carcinoma of skin 2 | 11
Strabismus 2 | 270
Telangiectasia of the skin 2 | 39
Thin skin 2 | 47
Tooth Abnormalities 2 | 69
Trichothiodystrophy 1, photosensitive 2 | 4
Trichothiodystrophy Syndromes 2 | 6
Xeroderma pigmentosum group F 2 | 22
Xeroderma pigmentosum-Cockayne syndrome complex 2 | 4
Xerosis 2 | 75
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
hearing impairment 2 | 199
hypopigmented skin patch 2 | 59
psoriasis 2 | 6,694
Enophthalmos 1 | 75
Joint stiffness 1 | 84
Spinal muscular atrophy 1 | 34
Telangiectasis 1 | 36

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634

Compartment GO Term

GO:0005675 11 | 11
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -1.32757 20.2 148
TFIIH basal transcription factor complex helicase XPD subunit ERCC2 Tbio Enzyme -2.58326 365.8 191
MMS19 nucleotide excision repair protein homolog MMS19 Tbio Non-IDG -1.66416 46.5 122
General transcription factor IIH subunit 2-like protein GTF2H2C_2 Tdark Non-IDG 0.78 0.25 76
General transcription factor IIH subunit 3 GTF2H3 Tbio Non-IDG -0.87291 7.21 78
Cyclin-dependent kinase 7 CDK7 Tchem Kinase -2.35186 219.0 582
Cyclin-H CCNH Tbio Non-IDG -2.02278 96.3 378
CDK-activating kinase assembly factor MAT1 MNAT1 Tbio Enzyme -2.13005 133.6 161
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.65323 46.0 231
General transcription factor IIH subunit 4 GTF2H4 Tbio Non-IDG -1.29930 19.8 148