Development Level

Tbio 29 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 3 | 278
abnormal retina morphology 2 | 71
increased circulating potassiu... 2 | 29
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
hydrometra 1 | 53
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 20 | 11,493
ovarian cancer 17 | 8,520
osteosarcoma 16 | 7,950
lung cancer 10 | 4,740
Cockayne syndrome 8 | 60
Photosensitive trichothiodystrophy 8 | 30
Breast cancer 6 | 3,578
Intellectual disability 6 | 1,016
Kidney cancer 6 | 2,613
Xeroderma pigmentosum group B 6 | 20
Epidermodysplasia verruciformis 5 | 21
Multiple myeloma 5 | 1,332
Xeroderma pigmentosum group D 5 | 33
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
psoriasis 5 | 6,694
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
Pick disease 4 | 1,894
Trichothiodystrophy Syndromes 4 | 6
adult high grade glioma 4 | 3,801
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Dull intelligence 3 | 645
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle Spasticity 3 | 195
Poor school performance 3 | 645
Small head 3 | 374
Spinocerebellar ataxia type 7 3 | 13
Trichothiodystrophy 1, photosensitive 3 | 4
Waldenstrons macroglobulinemia 3 | 765
Xeroderma pigmentosum 3 | 43
Xeroderma pigmentosum group G 3 | 16
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
Arthralgia 2 | 90
Atrophy of cerebellum 2 | 103
Basal cell carcinoma 2 | 54
Cachexia 2 | 50
Cerebellar degeneration 2 | 103
Chorea 2 | 29
Choreatic disease 2 | 52
Congenital deafness 2 | 185
Conjunctival telangiectasis 2 | 14
Deafness 2 | 198
Dental abnormalities 2 | 60
Developmental regression 2 | 95
Dry skin 2 | 75
Dystonia 2 | 164
Electroencephalogram abnormal 2 | 101
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Erythema 2 | 58
Failure to gain weight 2 | 365
Fatigue 2 | 182
Fever 2 | 138
Flushing 2 | 60
Freckles 2 | 33
Hearing Loss, Partial 2 | 185
Hyperkeratosis 2 | 50
Hyperreflexia 2 | 209
Impaired cognition 2 | 96
Infertility 2 | 188
Infratentorial atrophy 2 | 103
Keratitis 2 | 62
Loss of developmental milestones 2 | 95
Mental deterioration in childhood 2 | 95
Mental impairment 2 | 95
Myoclonus 2 | 74
Neurodevelopmental regression 2 | 95
Pediatric failure to thrive 2 | 365
Psychomotor regression 2 | 95
Psychomotor regression beginning in infancy 2 | 95
Psychomotor regression in infants 2 | 95
Psychomotor regression, progressive 2 | 95
Retinal Diseases 2 | 55
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Strabismus 2 | 270
Telangiectasia of the skin 2 | 39
Thin skin 2 | 47
Tooth Abnormalities 2 | 69
Xerosis 2 | 75
acute quadriplegic myopathy 2 | 1,158
cystic fibrosis 2 | 1,696
hearing impairment 2 | 199
hypopigmented skin patch 2 | 59
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Endocrine System 32 | 18,159
Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 2 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634

Compartment GO Term

GO:0005669 32 | 32
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.18859 223.1 91
Transcription initiation factor TFIID subunit 9B TAF9B Tbio Non-IDG -1.38372 23.5 105
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -1.32757 20.2 148
Transcription initiation factor TFIID subunit 6 TAF6 Tbio Non-IDG -1.10650 12.8 159
Transcription initiation factor TFIID subunit 2 TAF2 Tbio Non-IDG -1.33315 21.9 101
Transcription initiation factor TFIID subunit 1-like TAF1L Tchem Epigenetic -0.42674 2.72 43
Transcription initiation factor TFIID subunit 10 TAF10 Tbio Non-IDG -1.26261 15.2 107
Transcription initiation factor TFIID subunit 3 TAF3 Tbio Epigenetic -0.97631 8.71 103
Transcription initiation factor TFIID subunit 5 TAF5 Tbio Non-IDG -1.08338 9.03 81
Transcription initiation factor TFIID subunit 7 TAF7 Tbio Non-IDG -1.16026 13.4 138