Development Level

Tbio 182 | 11,445
Tchem 21 | 1,598
Tdark 14 | 6,588
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 27 | 979
embryonic lethality prior to t... 10 | 278
preweaning lethality, incomple... 8 | 499
embryonic lethality prior to o... 6 | 239
abnormal embryo size 5 | 220
abnormal heart morphology 5 | 162
abnormal seminal vesicle morph... 5 | 114
decreased vertical activity 5 | 208
abnormal retina morphology 4 | 71
decreased lymphocyte cell numb... 4 | 83
enlarged heart 4 | 210
increased circulating potassiu... 4 | 29
increased total body fat amoun... 4 | 134
abnormal kidney morphology 3 | 65
abnormal neural tube closure 3 | 46
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
increased lean body mass 3 | 172
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal craniofacial morpholo... 2 | 33
abnormal embryo turning 2 | 31
abnormal epididymis morphology 2 | 42
abnormal forebrain development 2 | 20
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal hindbrain development 2 | 16
abnormal ovary morphology 2 | 7
abnormal startle reflex 2 | 15
abnormal tooth morphology 2 | 24
absent epididymis 2 | 3
corneal opacity 2 | 32
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
embryonic growth retardation 2 | 106
hydrometra 2 | 53
hypoactivity 2 | 132
increased anti-nuclear antigen... 2 | 19
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
mammalian phenotype 2 | 17
prenatal lethality 2 | 28
prenatal lethality prior to he... 2 | 87
abnormal allantois morphology 1 | 8
abnormal chorioallantoic fusio... 1 | 8
abnormal cornea morphology 1 | 31
abnormal heart left ventricle ... 1 | 16
abnormal heart looping 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube morpholog... 1 | 12
abnormal optic disc morphology 1 | 10
abnormal optic vesicle formati... 1 | 4
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal retinal inner nuclear... 1 | 8
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
dilated heart left ventricle 1 | 11
edema 1 | 59
female infertility 1 | 60
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased B cell number 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
microphthalmia 1 | 26
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 136 | 11,493
osteosarcoma 117 | 7,950
ovarian cancer 116 | 8,520
psoriasis 86 | 6,694
medulloblastoma, large-cell 83 | 6,241
Cancer 81 | 2,499
lung cancer 79 | 4,740
glioblastoma 78 | 5,792
atypical teratoid / rhabdoid tumor 62 | 5,112
malignant mesothelioma 57 | 3,232
group 3 medulloblastoma 55 | 4,104
ependymoma 50 | 4,679
Breast cancer 48 | 3,578
primitive neuroectodermal tumor 44 | 3,035
oligodendroglioma 39 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
adult high grade glioma 37 | 3,801
Kidney cancer 35 | 2,613
diabetes mellitus 35 | 1,728
astrocytic glioma 34 | 2,597
invasive ductal carcinoma 34 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
lung adenocarcinoma 32 | 2,716
lung carcinoma 32 | 2,843
non-small cell lung cancer 32 | 2,890
pituitary cancer 32 | 1,972
pancreatic cancer 30 | 2,398
group 4 medulloblastoma 29 | 1,855
interstitial cystitis 28 | 2,312
ulcerative colitis 28 | 1,819
Pick disease 27 | 1,894
Intellectual disability 26 | 1,016
astrocytoma 25 | 1,146
breast carcinoma 25 | 1,638
subependymal giant cell astrocytoma 25 | 2,287
Rheumatoid arthritis 23 | 1,191
tuberculosis 23 | 2,010
colon cancer 22 | 1,478
ductal carcinoma in situ 22 | 1,745
Astrocytoma, Pilocytic 21 | 3,081
Multiple myeloma 21 | 1,332
acute quadriplegic myopathy 21 | 1,158
Obesity 20 | 678
cystic fibrosis 20 | 1,696
Autosomal recessive predisposition 19 | 1,442
Schizophrenia 19 | 1,160
dermatomyositis 19 | 966
primary pancreatic ductal adenocarcinoma 19 | 1,109
Breast Neoplasms 18 | 445
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Poor school performance 18 | 645
acute myeloid leukemia 17 | 783
juvenile dermatomyositis 17 | 1,187
pediatric high grade glioma 16 | 1,064
Mammary Neoplasms 15 | 425
adrenocortical carcinoma 15 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Bipolar Disorder 14 | 666
Melanoma 14 | 711
Short stature 14 | 531
Cryptorchidism 13 | 296
Prostatic Neoplasms 13 | 495
Small head 13 | 374
Waldenstrons macroglobulinemia 13 | 765
Cockayne syndrome 12 | 60
Epilepsy 12 | 792
Muscle hypotonia 12 | 571
Polycystic ovary syndrome 12 | 360
Cognitive delay 11 | 608
Colorectal Neoplasms 11 | 243
Craniofacial Abnormalities 11 | 151
Global developmental delay 11 | 608
Hypertensive disease 11 | 292
Kidney disease 11 | 430
Lung Neoplasms 11 | 232
Mental and motor retardation 11 | 608
Osteoporosis 11 | 363
Photosensitive trichothiodystrophy 11 | 30
Seizures 11 | 596
Strabismus 11 | 270
Xeroderma pigmentosum group B 11 | 20
aldosterone-producing adenoma 11 | 665
gastric carcinoma 11 | 807
nasopharyngeal carcinoma 11 | 1,058
Atopic dermatitis 10 | 952
Cleft Palate 10 | 271
Colonic Neoplasms 10 | 142
Depressive disorder 10 | 409
Endometriosis 10 | 540
Liver carcinoma 10 | 240
Mental Depression 10 | 333
Parkinson's disease 10 | 392
Vascular disease 10 | 319
non primary Sjogren syndrome sicca 10 | 891
primary Sjogren syndrome 10 | 735
sonic hedgehog group medulloblastoma 10 | 467

Tissue

Endocrine System 219 | 18,159
Digestive Tract 218 | 17,369
Female tissues 217 | 17,400
Male tissues 217 | 17,142
Skin and soft tissues 217 | 17,230
Blood and immune system 211 | 16,909
Urinary Tract 209 | 16,678
Liver and Pancreas 208 | 16,750
Respiratory system 208 | 16,393
Nervous System 207 | 16,725
Cardiovascular System 201 | 15,192

Target Family

Transcription Factor 101 | 1,400
Non-IDG 77 | 12,091
Enzyme 22 | 4,145
Epigenetic 9 | 242
Nuclear Receptor 8 | 48
Kinase 5 | 634
TF/Epigenetic 1 | 38

Compartment GO Term

GO:0005667 223 | 223
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
General transcription factor 3C polypeptide 5 GTF3C5 Tdark Non-IDG -0.17540 0.88 147
Transcriptional-regulating factor 1 TRERF1 Tbio Transcription Factor -0.69436 6.18 146
RNA-binding protein 14 RBM14 Tbio Non-IDG -2.10043 124.7 168
Achaete-scute homolog 4 ASCL4 Tdark Transcription Factor -0.31083 1.97 22
Mediator of RNA polymerase II transcription subunit 31 MED31 Tbio Enzyme -1.19048 15.1 61
Heterogeneous nuclear ribonucleoprotein A/B HNRNPAB Tbio Non-IDG -1.15839 12.5 96
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.18859 223.1 91
Transcription initiation factor TFIID subunit 9B TAF9B Tbio Non-IDG -1.38372 23.5 105
Protein BEX1 BEX1 Tbio Non-IDG -1.32314 23.8 124