Development Level

Tbio 35 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased food intake 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased large unstained cell... 1 | 5
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
tremors 1 | 39

Disease

Carcinoma 22 | 11,493
Azoospermia 17 | 110
osteosarcoma 16 | 7,950
glioblastoma 15 | 5,792
malignant mesothelioma 15 | 3,232
medulloblastoma, large-cell 15 | 6,241
Male infertility 14 | 206
ovarian cancer 14 | 8,520
psoriasis 14 | 6,694
Gonadoblastoma 13 | 34
Infertility 13 | 188
Klinefelter's syndrome 12 | 56
atypical teratoid / rhabdoid tumor 11 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung cancer 10 | 4,740
Cryptorchidism 9 | 296
Small testicle 9 | 75
primitive neuroectodermal tumor 9 | 3,035
Astrocytoma, Pilocytic 8 | 3,081
Oligospermia 8 | 36
Sertoli cell-only syndrome 8 | 37
Spermatogenic Failure, Nonobstructive, Y-Linked 8 | 15
cystic fibrosis 8 | 1,696
ependymoma 8 | 4,679
group 3 medulloblastoma 8 | 4,104
Breast cancer 7 | 3,578
Hypogonadism 7 | 173
Pick disease 7 | 1,894
Short stature 7 | 531
Turner syndrome 7 | 28
adult high grade glioma 7 | 3,801
astrocytic glioma 7 | 2,597
Kidney cancer 6 | 2,613
Partial chromosome Y deletion 6 | 7
adrenocortical carcinoma 6 | 1,428
juvenile dermatomyositis 6 | 1,187
oligodendroglioma 6 | 2,850
pediatric high grade glioma 6 | 1,064
Congenital hypoplasia of penis 5 | 176
Epilepsy 5 | 792
Hypogonadotropic hypogonadism 5 | 89
Hypospadias 5 | 53
Intellectual disability 5 | 1,016
Muscle hypotonia 5 | 571
Non-obstructive azoospermia 5 | 21
Polycystic ovary syndrome 5 | 360
Waldenstrons macroglobulinemia 5 | 765
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
non diabetic and post-ischemic heart failure 5 | 200
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
spina bifida 5 | 1,074
46 XY gonadal dysgenesis 4 | 10
Cancer 4 | 2,499
Gynecomastia 4 | 64
Hypogonadism, Isolated Hypogonadotropic 4 | 71
Kidney disease 4 | 430
Male Pseudohermaphroditism 4 | 19
Sclerocystic Ovaries 4 | 17
Seizures 4 | 596
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
non primary Sjogren syndrome sicca 4 | 891
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Abnormality of metabolism/homeostasis 3 | 134
Acquired scoliosis 3 | 281
Amyotrophic lateral sclerosis 3 | 451
Autistic Disorder 3 | 364
Big calvaria 3 | 147
Curvature of spine 3 | 282
Delayed Puberty 3 | 97
Down syndrome 3 | 499
Dysarthria 3 | 192
Failure to gain weight 3 | 365
Gonadal Dysgenesis 3 | 28
Hermaphroditism 3 | 9
Hypoplastic feet 3 | 66
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Osteoporosis 3 | 363
Pediatric failure to thrive 3 | 365
Penile hypospadias 3 | 106
Premature ovarian failure 3 | 65
Schizophrenia 3 | 1,160
Swyer Syndrome 3 | 8
Systemic lupus erythematosus 3 | 194
Testicular dysgenesis 3 | 9
X- linked recessive 3 | 110
X-linked cerebral adrenoleukodystrophy 3 | 116
X-linked dominant 3 | 57
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Endocrine System 40 | 18,159
Digestive Tract 31 | 17,369
Male tissues 31 | 17,142
Skin and soft tissues 30 | 17,230
Female tissues 29 | 17,400
Urinary Tract 28 | 16,678
Liver and Pancreas 27 | 16,750
Nervous System 27 | 16,725
Blood and immune system 26 | 16,909
Respiratory system 26 | 16,393
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 20 | 12,091
Transcription Factor 7 | 1,400
Epigenetic 6 | 242
Enzyme 5 | 4,145
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48
Transporter 1 | 473

Compartment GO Term

GO:0000803 42 | 42
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Doublesex- and mab-3-related transcription factor 1 DMRT1 Tbio Transcription Factor -2.31269 210.5 197
Testis-specific chromodomain protein Y 1 CDY1 Tbio Epigenetic -1.26646 18.6 30
Lysine-specific demethylase 5C KDM5C Tchem TF/Epigenetic -1.94004 86.4 135
Transcription factor SOX-3 SOX3 Tbio Transcription Factor -2.23686 175.4 207
Testis-specific Y-encoded protein 1 TSPY3 Tbio Non-IDG -2.00153 98.7 136
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Lysine-specific demethylase 5D KDM5D Tbio TF/Epigenetic -2.38009 240.2 32
Structural maintenance of chromosomes protein 6 SMC6 Tbio Non-IDG -1.42371 20.0 115
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Structural maintenance of chromosomes protein 5 SMC5 Tbio Non-IDG -1.90832 85.0 109