Development Level

Tbio 55 | 11,178
Tchem 20 | 1,885
Tdark 16 | 6,569
Tclin 1 | 612

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 14 | 979
male infertility 8 | 123
embryonic lethality prior to t... 6 | 278
embryonic lethality prior to o... 5 | 239
female infertility 5 | 60
abnormal embryo turning 3 | 31
decreased bone mineral content 3 | 151
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal tail morphology 2 | 25
decreased bone mineral density 2 | 126
embryonic growth retardation 2 | 106
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
shortened RR interval 2 | 17
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
pallor 1 | 34
sclerocornea 1 | 2
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened ST segment 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
urinary bladder obstruction 1 | 4

Disease

Carcinoma 61 | 11,192
ovarian cancer 45 | 8,297
osteosarcoma 41 | 7,766
glioblastoma 37 | 5,635
group 3 medulloblastoma 35 | 4,002
lung cancer 35 | 4,607
psoriasis 34 | 6,514
non-small cell lung cancer 33 | 2,799
medulloblastoma, large-cell 32 | 6,086
atypical teratoid / rhabdoid tumor 28 | 4,971
primitive neuroectodermal tumor 25 | 2,957
Breast cancer 24 | 3,469
Cancer 23 | 2,388
Kidney cancer 23 | 2,548
lung adenocarcinoma 22 | 2,627
malignant mesothelioma 22 | 3,135
invasive ductal carcinoma 20 | 2,867
adult high grade glioma 19 | 3,701
ependymoma 19 | 4,559
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,902
colon cancer 18 | 1,428
ductal carcinoma in situ 16 | 1,686
adrenocortical carcinoma 15 | 1,385
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,204
pancreatic cancer 15 | 2,322
breast carcinoma 14 | 1,589
Autosomal recessive predisposition 13 | 1,407
nasopharyngeal carcinoma 12 | 1,024
Male infertility 11 | 199
Short stature 11 | 514
Small head 11 | 366
Atopic dermatitis 10 | 915
Cognitive delay 10 | 596
Global developmental delay 10 | 596
Intellectual disability 10 | 998
Mental and motor retardation 10 | 596
cystic fibrosis 10 | 1,629
oligodendroglioma 10 | 2,768
Astrocytoma, Pilocytic 9 | 3,006
Dull intelligence 9 | 634
Endometriosis 9 | 521
Infertility 9 | 176
Low intelligence 9 | 634
Mental Retardation 9 | 634
Mental deficiency 9 | 634
Poor school performance 9 | 634
pituitary cancer 9 | 1,915
ulcerative colitis 9 | 1,765
lung carcinoma 8 | 2,755
Fetal Growth Retardation 7 | 186
Hypoplastic mandible condyle 7 | 273
Infant, Small for Gestational Age 7 | 174
Intrauterine retardation 7 | 174
Mandibular hypoplasia 7 | 273
Micrognathism 7 | 273
Prostatic Neoplasms 7 | 472
astrocytic glioma 7 | 2,530
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,872
Bilateral fifth finger clinodactyly 6 | 109
Cryptorchidism 6 | 287
Curvature of little finger 6 | 109
Liver cancer 6 | 589
Multiple myeloma 6 | 1,296
Pick disease 6 | 1,856
Premature ovarian failure 6 | 63
Waldenstrons macroglobulinemia 6 | 742
acute quadriplegic myopathy 6 | 1,133
esophageal adenocarcinoma 6 | 696
interstitial cystitis 6 | 2,237
juvenile dermatomyositis 6 | 1,147
non primary Sjogren syndrome sicca 6 | 861
Anteverted nostril 5 | 186
Anxiety 5 | 135
Anxiety disease 5 | 112
Ataxia telangiectasia 5 | 33
Attention deficit hyperactivity disorder 5 | 272
Azoospermia 5 | 106
Blepharoptosis 5 | 229
Brachycephaly 5 | 86
Broad cranium shape 5 | 86
Concave bridge of nose 5 | 191
Delayed bone age 5 | 132
Depressed nasal bridge 5 | 191
Depressed nasal root/bridge 5 | 191
Endometrial cancer 5 | 301
Low anterior hairline 5 | 30
Microcephaly 5 | 166
Muscle Hypertonia 5 | 88
Penile hypospadias 5 | 102
Rheumatoid arthritis 5 | 1,156
Short nose 5 | 127
Small nose 5 | 127
Wide skull shape 5 | 86
dermatomyositis 5 | 941
group 4 medulloblastoma 5 | 1,806
medulloblastoma 5 | 702
pediatric high grade glioma 5 | 1,035
tuberculosis and treatment for 6 months 5 | 399
cutaneous lupus erythematosus 4 | 1,016
primary Sjogren syndrome 4 | 710

Tissue

Endocrine System 92 | 18,159
Female tissues 90 | 17,400
Digestive Tract 89 | 17,369
Blood and immune system 88 | 16,909
Skin and soft tissues 88 | 17,230
Male tissues 87 | 17,142
Liver and Pancreas 85 | 16,750
Nervous System 84 | 16,725
Urinary Tract 84 | 16,678
Respiratory system 83 | 16,393
Cardiovascular System 76 | 15,192

Target Family

Non-IDG 63 | 12,091
Enzyme 11 | 4,145
Kinase 9 | 634
Ion Channel 3 | 344
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Transporter 2 | 473

Compartment GO Term

GO:0000794 92 | 92
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptonemal complex protein 2-like SYCP2L Tdark Non-IDG -0.43581 2.70 15
Protein SIX6OS1 C14orf39 Tdark Non-IDG 0.30 0.90 6
Calcium-activated chloride channel regulator 1 CLCA1 Tchem Ion Channel -2.17352 137.8 159
Zinc transporter ZIP2 SLC39A2 Tbio Transporter -1.63982 41.5 59
Probable E3 SUMO-protein ligase RNF212 RNF212 Tbio Enzyme -0.94925 8.45 87
Grancalcin GCA Tbio Non-IDG -2.00540 93.2 76
Structural maintenance of chromosomes protein 1A SMC1A Tbio Non-IDG -1.84148 64.7 686
Twist-related protein 1 TWIST1 Tbio Transcription Factor -3.91883 8025.6 425
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376