Development Level

Tbio 62 | 11,651
Tdark 16 | 6,593
Tchem 15 | 1,388
Tclin 1 | 612

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 14 | 979
male infertility 8 | 123
embryonic lethality prior to t... 6 | 278
embryonic lethality prior to o... 5 | 239
female infertility 5 | 60
abnormal embryo turning 3 | 31
decreased bone mineral content 3 | 151
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal tail morphology 2 | 25
decreased bone mineral density 2 | 126
embryonic growth retardation 2 | 106
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
shortened RR interval 2 | 17
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
pallor 1 | 34
sclerocornea 1 | 2
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened ST segment 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
urinary bladder obstruction 1 | 4

Disease

Carcinoma 63 | 11,493
ovarian cancer 47 | 8,520
osteosarcoma 42 | 7,950
glioblastoma 39 | 5,792
lung cancer 37 | 4,740
group 3 medulloblastoma 36 | 4,104
psoriasis 35 | 6,694
non-small cell lung cancer 34 | 2,890
medulloblastoma, large-cell 33 | 6,241
atypical teratoid / rhabdoid tumor 29 | 5,112
primitive neuroectodermal tumor 27 | 3,035
Breast cancer 25 | 3,578
Cancer 24 | 2,499
Kidney cancer 24 | 2,613
lung adenocarcinoma 24 | 2,716
malignant mesothelioma 24 | 3,232
ependymoma 20 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
invasive ductal carcinoma 20 | 2,951
adult high grade glioma 19 | 3,801
colon cancer 19 | 1,478
ductal carcinoma in situ 17 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
adrenocortical carcinoma 15 | 1,428
breast carcinoma 15 | 1,638
pancreatic cancer 15 | 2,398
Autosomal recessive predisposition 14 | 1,442
nasopharyngeal carcinoma 13 | 1,058
Short stature 12 | 531
Small head 12 | 374
Intellectual disability 11 | 1,016
Male infertility 11 | 206
Atopic dermatitis 10 | 952
Cognitive delay 10 | 608
Dull intelligence 10 | 645
Global developmental delay 10 | 608
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental and motor retardation 10 | 608
Mental deficiency 10 | 645
Poor school performance 10 | 645
cystic fibrosis 10 | 1,696
oligodendroglioma 10 | 2,850
Astrocytoma, Pilocytic 9 | 3,081
Endometriosis 9 | 540
Infertility 9 | 188
pituitary cancer 9 | 1,972
ulcerative colitis 9 | 1,819
Prostatic Neoplasms 8 | 495
lung carcinoma 8 | 2,843
Fetal Growth Retardation 7 | 189
Hypoplastic mandible condyle 7 | 275
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
Liver cancer 7 | 604
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Multiple myeloma 7 | 1,332
Pick disease 7 | 1,894
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Anteverted nostril 6 | 191
Ataxia telangiectasia 6 | 34
Bilateral fifth finger clinodactyly 6 | 110
Brachycephaly 6 | 88
Broad cranium shape 6 | 88
Concave bridge of nose 6 | 195
Cryptorchidism 6 | 296
Curvature of little finger 6 | 110
Delayed bone age 6 | 136
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Premature ovarian failure 6 | 65
Schizophrenia 6 | 1,160
Short nose 6 | 132
Small nose 6 | 132
Waldenstrons macroglobulinemia 6 | 765
Wide skull shape 6 | 88
acute quadriplegic myopathy 6 | 1,158
esophageal adenocarcinoma 6 | 737
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
juvenile dermatomyositis 6 | 1,187
non primary Sjogren syndrome sicca 6 | 891
pediatric high grade glioma 6 | 1,064
Attention deficit hyperactivity disorder 5 | 278
Blepharoptosis 5 | 231
Endometrial cancer 5 | 311
Epilepsy 5 | 792
Mammary Neoplasms 5 | 425
Microcephaly 5 | 166
Muscle Hypertonia 5 | 88
Penile hypospadias 5 | 106
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
dermatomyositis 5 | 966
medulloblastoma 5 | 720
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
progressive supranuclear palsy 5 | 676
tuberculosis and treatment for 6 months 5 | 409

Tissue

Endocrine System 94 | 18,159
Female tissues 92 | 17,400
Digestive Tract 91 | 17,369
Blood and immune system 90 | 16,909
Skin and soft tissues 90 | 17,230
Male tissues 89 | 17,142
Liver and Pancreas 87 | 16,750
Nervous System 86 | 16,725
Urinary Tract 86 | 16,678
Respiratory system 85 | 16,393
Cardiovascular System 78 | 15,192

Target Family

Non-IDG 64 | 12,091
Enzyme 12 | 4,145
Kinase 9 | 634
Ion Channel 3 | 344
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Transporter 2 | 473

Compartment GO Term

GO:0000794 94 | 94
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MutS protein homolog 5 MSH5 Tbio Non-IDG -1.75314 0.00000 142
Cell cycle checkpoint control protein RAD9B RAD9B Tdark Non-IDG -0.07767 1.44 35
Zinc transporter ZIP1 SLC39A1 Tbio Transporter -1.89903 75.9 61
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.73322 567.0 386
Feline leukemia virus subgroup C receptor-related protein 2 FLVCR2 Tbio Non-IDG -2.02537 101.6 84
Mitotic checkpoint serine/threonine-protein kinase BUB1 BUB1 Tchem Kinase -2.31533 200.0 373
Testis-expressed protein 12 TEX12 Tdark Non-IDG -0.49336 2.83 83
Mis18-binding protein 1 MIS18BP1 Tdark Non-IDG -1.12057 12.9 47
SUMO-conjugating enzyme UBC9 UBE2I Tbio Non-IDG -2.45979 267.1 368
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542