Development Level

Tbio 57 | 10,625
Tchem 21 | 1,890
Tdark 10 | 7,003
Tclin 1 | 602

Collection

Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 8 | 633
embryonic lethality prior to t... 4 | 187
abnormal behavioral response t... 3 | 52
embryonic lethality prior to o... 3 | 148
male infertility 3 | 62
abnormal bone structure 2 | 131
decreased bone mineral content 2 | 157
female infertility 2 | 34
increased mean corpuscular hem... 2 | 93
abnormal coat/hair pigmentatio... 1 | 54
abnormal retinal pigmentation 1 | 61
abnormal spleen morphology 1 | 36
abnormal tail morphology 1 | 17
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 121
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
impaired glucose tolerance 1 | 52
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased exploration in new e... 1 | 56
increased heart rate 1 | 17
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
polydactyly 1 | 22
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
shortened RR interval 1 | 19
shortened ST segment 1 | 9
small testis 1 | 37
thin tail 1 | 1
urinary bladder obstruction 1 | 2

Disease

ovarian cancer 47 | 8,484
osteosarcoma 39 | 7,933
lung cancer 37 | 4,466
glioblastoma 36 | 5,572
psoriasis 35 | 6,685
non-small cell lung cancer 34 | 2,798
medulloblastoma, large-cell 32 | 6,234
primitive neuroectodermal tumor 26 | 3,031
group 3 medulloblastoma 24 | 2,254
lung adenocarcinoma 24 | 2,713
malignant mesothelioma 24 | 3,162
Breast cancer 23 | 3,094
Cancer 23 | 2,346
atypical teratoid / rhabdoid tumor 23 | 4,369
colon cancer 20 | 1,475
invasive ductal carcinoma 20 | 2,950
pediatric high grade glioma 20 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
Carcinoma 17 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
ductal carcinoma in situ 16 | 1,745
pancreatic cancer 15 | 2,300
adrenocortical carcinoma 14 | 1,427
posterior fossa group A ependymoma 14 | 1,511
nasopharyngeal carcinoma 13 | 1,056
breast carcinoma 11 | 1,614
Male infertility 10 | 170
cystic fibrosis 10 | 1,665
oligodendroglioma 10 | 2,849
ulcerative colitis 10 | 2,087
Atopic dermatitis 9 | 944
IGA Glomerulonephritis 9 | 454
atypical teratoid/rhabdoid tumor 9 | 1,095
pilocytic astrocytoma 9 | 3,086
Endometriosis 8 | 535
Infertility 8 | 163
Pick disease 8 | 1,893
acute quadriplegic myopathy 8 | 1,157
ependymoma 8 | 2,514
lung carcinoma 8 | 2,844
pituitary cancer 8 | 1,972
sonic hedgehog group medulloblastoma 8 | 1,482
Multiple myeloma 7 | 1,327
Prostatic Neoplasms 7 | 471
Waldenstrons macroglobulinemia 7 | 765
astrocytic glioma 7 | 2,241
esophageal adenocarcinoma 7 | 737
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
medulloblastoma 7 | 1,524
Ataxia telangiectasia 6 | 31
Mammary Neoplasms 6 | 410
Neoplastic Syndromes, Hereditary 6 | 48
juvenile dermatomyositis 6 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
progressive supranuclear palsy 6 | 674
tuberculosis and treatment for 6 months 6 | 686
Hereditary Breast and Ovarian Cancer Syndrome 5 | 14
Intellectual disability 5 | 573
Lynch syndrome 5 | 33
Nijmegen breakage syndrome 5 | 23
Peripheral Neuropathy 5 | 303
Rheumatoid Arthritis 5 | 1,160
dermatomyositis 5 | 933
group 4 medulloblastoma 5 | 1,875
interstitial cystitis 5 | 2,299
non primary Sjogren syndrome sicca 5 | 840
Bloom syndrome 4 | 30
Melanoma 4 | 261
Microcephaly 4 | 149
adult high grade glioma 4 | 2,148
cutaneous lupus erythematosus 4 | 1,056
diabetes mellitus 4 | 1,663
ovarian neoplasm 4 | 97
pancreatic carcinoma 4 | 567
primary Sjogren syndrome 4 | 789
Acrodermatitis enteropathica 3 | 18
Amyotrophic Lateral Sclerosis 3 | 431
Anemia 3 | 252
Breast Cancer, Familial 3 | 12
Cerebrovascular disease 3 | 231
Colorectal Neoplasms 3 | 217
Cornelia de Lange syndrome 3 | 21
Fanconi's anemia 3 | 50
Hereditary Nonpolyposis Colorectal Cancer 3 | 13
Hereditary breast ovarian cancer 3 | 6
KBG syndrome 3 | 8
Malignant neoplasm of breast 3 | 63
Mammary Neoplasms, Experimental 3 | 150
Myeloid Leukemia 3 | 19
Neoplasm Metastasis 3 | 138
Pancreatic Neoplasm 3 | 79
Premature menopause 3 | 7
Premature ovarian failure 3 | 64
Prostate cancer 3 | 172
acute myeloid leukemia 3 | 780
astrocytoma 3 | 1,493
inflammatory breast cancer 3 | 404
spina bifida 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 1,557

Tissue

Blood and immune system 89 | 17,995
Endocrine System 89 | 18,512
Female tissues 89 | 18,647
Male tissues 89 | 17,969
Nervous System 89 | 18,561
Skin and soft tissues 89 | 18,115
Urinary Tract 89 | 18,444
Cardiovascular System 88 | 17,958
Digestive Tract 88 | 18,473
Liver and Pancreas 88 | 18,136
Respiratory system 88 | 17,484

Target Family

Non-IDG 58 | 11,971
Enzyme 12 | 4,146
Kinase 8 | 634
Ion Channel 3 | 341
Transcription Factor 3 | 1,400
Transporter 3 | 473
Epigenetic 2 | 242

Compartment GO Term

GO:0000794 89 | 89
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.68837 532.8 347
Structural maintenance of chromosomes protein 1B SMC1B Tbio Non-IDG -1.26509 19.6 93
Protein MIS12 homolog MIS12 Tbio Non-IDG -0.84532 5.38 97
Gamma-glutamylcyclotransferase GGCT Tbio Enzyme -2.15784 135.0 114
Synaptonemal complex protein 3 SYCP3 Tbio Non-IDG -2.15623 144.9 251
Synaptonemal complex central element protein 3 SYCE3 Tdark Non-IDG -0.73316 6.63 5
Structural maintenance of chromosomes protein 3 SMC3 Tbio Non-IDG -2.05162 104.9 234
MutS protein homolog 4 MSH4 Tbio Non-IDG -1.85039 70.8 78
Checkpoint protein HUS1B HUS1B Tdark Non-IDG -0.33244 1.78 53