Development Level

Tbio 156 | 11,178
Tdark 34 | 6,569
Tchem 26 | 1,885
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 36 | 979
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 8 | 278
male infertility 8 | 123
cataract 5 | 92
embryonic growth retardation 5 | 106
female infertility 5 | 60
preweaning lethality, incomple... 5 | 499
abnormal behavioral response t... 4 | 66
abnormal embryo size 4 | 220
abnormal lens morphology 4 | 81
abnormal tail morphology 4 | 25
decreased bone mineral content 4 | 151
increased circulating HDL chol... 4 | 80
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
abnormal embryo turning 3 | 31
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral density 3 | 126
decreased circulating choleste... 3 | 93
impaired glucose tolerance 3 | 75
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
small testis 3 | 58
abnormal coat-hair pigmentatio... 2 | 64
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating alanine ... 2 | 47
decreased circulating iron lev... 2 | 32
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
shortened RR interval 2 | 17
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal retinal inner nuclear... 1 | 8
abnormal skin coloration 1 | 25
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating free fat... 1 | 31
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
edema 1 | 59
hemorrhage 1 | 23
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased heart rate 1 | 23
increased or absent threshold ... 1 | 101
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small kidney 1 | 16
small spleen 1 | 19
syndactyly 1 | 23
tremors 1 | 39
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

Carcinoma 141 | 11,192
ovarian cancer 128 | 8,297
medulloblastoma, large-cell 110 | 6,086
osteosarcoma 105 | 7,766
group 3 medulloblastoma 100 | 4,002
glioblastoma 99 | 5,635
psoriasis 98 | 6,514
lung cancer 93 | 4,607
atypical teratoid / rhabdoid tumor 90 | 4,971
primitive neuroectodermal tumor 82 | 2,957
Breast cancer 81 | 3,469
non-small cell lung cancer 72 | 2,799
adult high grade glioma 66 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 66 | 3,204
intraductal papillary-mucinous carcinoma (IPMC) 64 | 2,902
ependymoma 61 | 4,559
lung adenocarcinoma 58 | 2,627
invasive ductal carcinoma 57 | 2,867
adrenocortical carcinoma 56 | 1,385
malignant mesothelioma 56 | 3,135
Kidney cancer 49 | 2,548
Cancer 48 | 2,388
ductal carcinoma in situ 41 | 1,686
oligodendroglioma 40 | 2,768
colon cancer 39 | 1,428
pancreatic cancer 33 | 2,322
Endometriosis 32 | 521
breast carcinoma 32 | 1,589
Atopic dermatitis 31 | 915
nasopharyngeal carcinoma 31 | 1,024
astrocytic glioma 29 | 2,530
Intellectual disability 27 | 998
Astrocytoma, Pilocytic 26 | 3,006
Pick disease 25 | 1,856
Waldenstrons macroglobulinemia 25 | 742
Multiple myeloma 24 | 1,296
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,872
ulcerative colitis 21 | 1,765
Autosomal recessive predisposition 20 | 1,407
Small head 20 | 366
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,911
Dull intelligence 17 | 634
Low intelligence 17 | 634
Mental Retardation 17 | 634
Mental deficiency 17 | 634
Poor school performance 17 | 634
Short stature 17 | 514
group 4 medulloblastoma 17 | 1,806
pituitary cancer 17 | 1,915
primary Sjogren syndrome 17 | 710
Cognitive delay 16 | 596
Global developmental delay 16 | 596
Mental and motor retardation 16 | 596
acute quadriplegic myopathy 16 | 1,133
non primary Sjogren syndrome sicca 16 | 861
pediatric high grade glioma 16 | 1,035
subependymal giant cell astrocytoma 16 | 2,230
Microcephaly 15 | 166
dermatomyositis 15 | 941
interstitial cystitis 15 | 2,237
lung carcinoma 15 | 2,755
Rheumatoid arthritis 14 | 1,156
juvenile dermatomyositis 14 | 1,147
progressive supranuclear palsy 14 | 656
astrocytoma 13 | 1,113
Hypoplastic mandible condyle 12 | 273
Male infertility 12 | 199
Mandibular hypoplasia 12 | 273
Micrognathism 12 | 273
Roberts syndrome 12 | 15
Cryptorchidism 11 | 287
Fetal Growth Retardation 11 | 186
Infant, Small for Gestational Age 11 | 174
Intrauterine retardation 11 | 174
tuberculosis 11 | 1,963
Alzheimer's disease 10 | 640
Cornelia de Lange syndrome 10 | 20
Fanconi anemia 10 | 56
Infertility 10 | 176
Amyotrophic lateral sclerosis 9 | 437
Epilepsy 9 | 775
Schizophrenia 9 | 1,136
cystic fibrosis 9 | 1,629
diabetes mellitus 9 | 1,683
medulloblastoma 9 | 702
posterior fossa group A ependymoma 9 | 456
Bilateral fifth finger clinodactyly 8 | 109
Curvature of little finger 8 | 109
Delayed bone age 8 | 132
Liver cancer 8 | 589
Prostatic Neoplasms 8 | 472
active Crohn's disease 8 | 882
acute myeloid leukemia 8 | 760
cutaneous lupus erythematosus 8 | 1,016
esophageal adenocarcinoma 8 | 696
pancreatic carcinoma 8 | 555
Attention deficit hyperactivity disorder 7 | 272
Bipolar Disorder 7 | 646
Seizures 7 | 584
primary pancreatic ductal adenocarcinoma 7 | 1,071

Tissue

Endocrine System 214 | 18,159
Female tissues 210 | 17,400
Digestive Tract 209 | 17,369
Blood and immune system 208 | 16,909
Skin and soft tissues 208 | 17,230
Male tissues 207 | 17,142
Respiratory system 205 | 16,393
Liver and Pancreas 204 | 16,750
Nervous System 204 | 16,725
Urinary Tract 204 | 16,678
Cardiovascular System 193 | 15,192

Target Family

Non-IDG 164 | 12,091
Enzyme 22 | 4,145
Kinase 14 | 634
Epigenetic 7 | 242
Transcription Factor 6 | 1,400
Transporter 2 | 473
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

GO:0000793 217 | 217
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MyoD family inhibitor domain-containing protein MDFIC Tbio Non-IDG -2.90969 749.0 122
ATP-dependent DNA helicase DDX11 DDX11 Tbio Enzyme -1.05592 30.0 163
Centromere protein N CENPN Tbio Non-IDG -0.88756 6.97 80
Synaptonemal complex protein 2-like SYCP2L Tdark Non-IDG -0.43581 2.70 15
Protein SIX6OS1 C14orf39 Tdark Non-IDG 0.30 0.90 6
Cytoskeleton-associated protein 5 CKAP5 Tbio Non-IDG -2.12618 129.3 77
Centromere protein S CENPS Tbio Non-IDG -2.05081 96.7 62
Structural maintenance of chromosomes protein 4 SMC4 Tbio Non-IDG -1.49520 28.0 167
Structural maintenance of chromosomes protein 2 SMC2 Tbio Non-IDG -0.69216 5.13 188
Non-structural maintenance of chromosomes element 3 homolog NSMCE3 Tbio Non-IDG -1.07832 11.9 26