Development Level

Tbio 162 | 11,651
Tdark 34 | 6,593
Tchem 23 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 36 | 979
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 8 | 278
male infertility 8 | 123
preweaning lethality, incomple... 6 | 499
abnormal embryo size 5 | 220
cataract 5 | 92
embryonic growth retardation 5 | 106
female infertility 5 | 60
abnormal behavioral response t... 4 | 66
abnormal lens morphology 4 | 81
abnormal tail morphology 4 | 25
decreased bone mineral content 4 | 151
increased circulating HDL chol... 4 | 80
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
abnormal embryo turning 3 | 31
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral density 3 | 126
decreased circulating choleste... 3 | 93
impaired glucose tolerance 3 | 75
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
small testis 3 | 58
abnormal coat-hair pigmentatio... 2 | 64
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating alanine ... 2 | 47
decreased circulating iron lev... 2 | 32
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
shortened RR interval 2 | 17
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating free fat... 1 | 31
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
edema 1 | 59
hemorrhage 1 | 23
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased heart rate 1 | 23
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small kidney 1 | 16
small spleen 1 | 19
syndactyly 1 | 23
tremors 1 | 39
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

Carcinoma 143 | 11,493
ovarian cancer 130 | 8,520
medulloblastoma, large-cell 113 | 6,241
osteosarcoma 107 | 7,950
group 3 medulloblastoma 102 | 4,104
glioblastoma 101 | 5,792
psoriasis 99 | 6,694
lung cancer 95 | 4,740
atypical teratoid / rhabdoid tumor 91 | 5,112
Breast cancer 84 | 3,578
primitive neuroectodermal tumor 84 | 3,035
non-small cell lung cancer 74 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 68 | 3,291
adult high grade glioma 67 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,989
ependymoma 62 | 4,679
lung adenocarcinoma 60 | 2,716
invasive ductal carcinoma 58 | 2,951
adrenocortical carcinoma 57 | 1,428
malignant mesothelioma 57 | 3,232
Cancer 51 | 2,499
Kidney cancer 50 | 2,613
ductal carcinoma in situ 43 | 1,745
colon cancer 41 | 1,478
oligodendroglioma 40 | 2,850
breast carcinoma 34 | 1,638
pancreatic cancer 34 | 2,398
Endometriosis 33 | 540
nasopharyngeal carcinoma 33 | 1,058
Atopic dermatitis 32 | 952
astrocytic glioma 29 | 2,597
Intellectual disability 27 | 1,016
Astrocytoma, Pilocytic 26 | 3,081
Pick disease 25 | 1,894
Waldenstrons macroglobulinemia 25 | 765
Multiple myeloma 24 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
ulcerative colitis 21 | 1,819
Autosomal recessive predisposition 20 | 1,442
Small head 20 | 374
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Dull intelligence 17 | 645
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
Short stature 17 | 531
group 4 medulloblastoma 17 | 1,855
pituitary cancer 17 | 1,972
primary Sjogren syndrome 17 | 735
Cognitive delay 16 | 608
Global developmental delay 16 | 608
Mental and motor retardation 16 | 608
acute quadriplegic myopathy 16 | 1,158
non primary Sjogren syndrome sicca 16 | 891
pediatric high grade glioma 16 | 1,064
subependymal giant cell astrocytoma 16 | 2,287
Microcephaly 15 | 166
dermatomyositis 15 | 966
interstitial cystitis 15 | 2,312
lung carcinoma 15 | 2,843
Rheumatoid arthritis 14 | 1,191
juvenile dermatomyositis 14 | 1,187
progressive supranuclear palsy 14 | 676
astrocytoma 13 | 1,146
Hypoplastic mandible condyle 12 | 275
Male infertility 12 | 206
Mandibular hypoplasia 12 | 275
Micrognathism 12 | 275
Roberts syndrome 12 | 15
tuberculosis 12 | 2,010
Cryptorchidism 11 | 296
Fetal Growth Retardation 11 | 189
Infant, Small for Gestational Age 11 | 176
Intrauterine retardation 11 | 176
Alzheimer's disease 10 | 658
Cornelia de Lange syndrome 10 | 21
Fanconi anemia 10 | 56
Infertility 10 | 188
Schizophrenia 10 | 1,160
posterior fossa group A ependymoma 10 | 468
Amyotrophic lateral sclerosis 9 | 451
Epilepsy 9 | 792
Liver cancer 9 | 604
Prostatic Neoplasms 9 | 495
cystic fibrosis 9 | 1,696
diabetes mellitus 9 | 1,728
medulloblastoma 9 | 720
Bilateral fifth finger clinodactyly 8 | 110
Curvature of little finger 8 | 110
Delayed bone age 8 | 136
active Crohn's disease 8 | 922
acute myeloid leukemia 8 | 783
cutaneous lupus erythematosus 8 | 1,057
esophageal adenocarcinoma 8 | 737
pancreatic carcinoma 8 | 562
Attention deficit hyperactivity disorder 7 | 278
Bipolar Disorder 7 | 666
Seizures 7 | 596
primary pancreatic ductal adenocarcinoma 7 | 1,109

Tissue

Endocrine System 217 | 18,159
Female tissues 213 | 17,400
Digestive Tract 212 | 17,369
Blood and immune system 211 | 16,909
Skin and soft tissues 211 | 17,230
Male tissues 210 | 17,142
Respiratory system 208 | 16,393
Liver and Pancreas 207 | 16,750
Nervous System 207 | 16,725
Urinary Tract 207 | 16,678
Cardiovascular System 196 | 15,192

Target Family

Non-IDG 166 | 12,091
Enzyme 22 | 4,145
Kinase 14 | 634
Epigenetic 7 | 242
Transcription Factor 7 | 1,400
Transporter 2 | 473
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

GO:0000793 220 | 220
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromosome alignment-maintaining phosphoprotein 1 CHAMP1 Tbio Non-IDG -0.61730 4.58 106
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
Securin PTTG1 Tbio Non-IDG -2.42127 261.4 311
MutS protein homolog 5 MSH5 Tbio Non-IDG -1.75314 0.00000 142
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Cell cycle checkpoint control protein RAD9B RAD9B Tdark Non-IDG -0.07767 1.44 35
Zinc transporter ZIP1 SLC39A1 Tbio Transporter -1.89903 75.9 61
Centromere protein O CENPO Tbio Non-IDG -0.67552 5.22 124
Dynactin subunit 5 DCTN5 Tdark Non-IDG -0.32495 0.71 53
Lethal(3)malignant brain tumor-like protein 1 L3MBTL1 Tchem TF/Epigenetic -2.45676 284.5 106