Development Level

Tbio 16 | 11,651
Tdark 3 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
prenatal lethality 2 | 28
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal head shape 1 | 10
abnormal head size 1 | 6
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal skin coloration 1 | 25
anophthalmia 1 | 33
cataract 1 | 92
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased fasted circulating g... 1 | 76
irregularly shaped pupil 1 | 7
microcephaly 1 | 1
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 14 | 11,493
medulloblastoma, large-cell 9 | 6,241
ovarian cancer 9 | 8,520
osteosarcoma 8 | 7,950
lung cancer 7 | 4,740
astrocytic glioma 6 | 2,597
glioblastoma 6 | 5,792
psoriasis 6 | 6,694
malignant mesothelioma 5 | 3,232
Breast cancer 4 | 3,578
Epilepsy 4 | 792
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
Epilepsy, Partial, with Variable Foci 3 | 3
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
dermatomyositis 3 | 966
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
Omenn syndrome 2 | 13
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
Absence Epilepsy 1 | 22
Acquired immunodeficiency syndrome 1 | 197
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Anemia 1 | 365
Astrocytoma, Pilocytic 1 | 3,081
Attention deficit hyperactivity disorder 1 | 278
Barrett's esophagus 1 | 182
Birt-Hogg-Dube syndrome 1 | 11
Blepharoptosis 1 | 231
Bowed and upward slanting eyebrows 1 | 41
Cancer 1 | 2,499
Carcinoma, Hepatocellular 1 | 228
Chemical and Drug Induced Liver Injury 1 | 195
Clonorchiasis 1 | 13
Cognitive disorder 1 | 50
Congenital dyserythropoietic anemia 1 | 18
Decreased tendon reflex 1 | 122
Distal arthrogryposis 1 | 42
Downward slant of palpebral fissure 1 | 158
EPILEPSY, LATERAL TEMPORAL LOBE, AUTOSOMAL DOMINANT 1 | 3
Echinococcosis 1 | 26
Electroencephalogram abnormal 1 | 101
Endometrial cancer 1 | 311
Epilepsy, Familial Temporal Lobe, 1 1 | 3
Epileptic encephalopathy 1 | 26
Hemolytic anemia 1 | 77
Hepatitis C 1 | 94
Hepatomegaly 1 | 285
High forehead 1 | 102
Liver cancer 1 | 604
Liver carcinoma 1 | 240
Liver neoplasms 1 | 130
Lymphoma, Follicular 1 | 18
Melanoma 1 | 711
Nail disease 1 | 9
Paragonimiasis 1 | 8
Peanut allergy 1 | 11
Peripheral vascular disease 1 | 87
Polycystic ovary syndrome 1 | 360
Reperfusion Injury 1 | 86
Retinitis pigmentosa 23 1 | 27
Right atrial isomerism 1 | 29
Schizoaffective Disorder 1 | 55
Schizophrenia 1 | 1,160
Seizures 1 | 596
Seizures, Focal 1 | 14
Sickle Cell Anemia 1 | 53
Stomatitis 1 | 21
Tall forehead 1 | 102
Thalassemia 1 | 53
Thick, flared eyebrows 1 | 41
Type 2 diabetes mellitus 1 | 272
adrenocortical carcinoma 1 | 1,428
breast carcinoma 1 | 1,638
esophageal adenocarcinoma 1 | 737
gastric carcinoma 1 | 807
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 19 | 16,909
Cardiovascular System 19 | 15,192
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678

Target Family

Non-IDG 16 | 12,091
Enzyme 2 | 4,145
Transporter 1 | 473

Compartment GO Term

GATOR2 complex 19 | 19
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GATOR complex protein NPRL2 NPRL2 Tbio Enzyme -1.30624 22.7 214
GATOR complex protein MIOS MIOS Tdark Non-IDG -1.44864 28.1 21
GATOR complex protein NPRL3 NPRL3 Tbio Enzyme -2.09240 119.0 52
Ephrin-A5 EFNA5 Tbio Non-IDG -2.57120 355.6 202
KICSTOR complex protein ITFG2 ITFG2 Tbio Non-IDG -0.08715 1.19 148
Sestrin-2 SESN2 Tbio Non-IDG -1.88129 92.6 176
Ras-related GTP-binding protein B RRAGB Tbio Non-IDG -1.40729 26.2 113
Nucleoporin SEH1 SEH1L Tbio Non-IDG -0.92247 6.52 11
Sestrin-1 SESN1 Tbio Non-IDG -1.95681 82.0 172
GATOR complex protein WDR24 WDR24 Tdark Non-IDG 0.16 1.02 28