Development Level

Tbio 19 | 11,445
Tchem 4 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal rib morphology 1 | 10
cataract 1 | 92
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
edema 1 | 59
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased red blood cell distr... 1 | 34
thin ventricular wall 1 | 24

Disease

Carcinoma 25 | 11,493
atypical teratoid / rhabdoid tumor 21 | 5,112
medulloblastoma, large-cell 21 | 6,241
glioblastoma 20 | 5,792
ependymoma 19 | 4,679
Epilepsy 17 | 792
Schizophrenia 16 | 1,160
adult high grade glioma 15 | 3,801
ovarian cancer 14 | 8,520
group 3 medulloblastoma 13 | 4,104
Astrocytoma, Pilocytic 12 | 3,081
Autistic Disorder 12 | 364
osteosarcoma 12 | 7,950
primitive neuroectodermal tumor 12 | 3,035
oligodendroglioma 11 | 2,850
Bipolar Disorder 10 | 666
Seizures 10 | 596
astrocytic glioma 10 | 2,597
lung cancer 10 | 4,740
psoriasis 10 | 6,694
Alcoholic Intoxication, Chronic 9 | 289
Kidney cancer 9 | 2,613
subependymal giant cell astrocytoma 9 | 2,287
Alzheimer's disease 7 | 658
Cocaine-Related Disorders 7 | 92
Major Depressive Disorder 7 | 301
Parkinson's disease 7 | 392
Pick disease 7 | 1,894
pituitary cancer 7 | 1,972
Breast cancer 6 | 3,578
Intellectual disability 6 | 1,016
Mental Depression 6 | 333
Status Epilepticus 6 | 98
Unipolar Depression 6 | 250
lung carcinoma 6 | 2,843
Depressive disorder 5 | 409
Mood Disorders 5 | 184
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
Alcohol dependence 4 | 107
Autism spectrum disorder 4 | 101
Down syndrome 4 | 499
Glaucoma 4 | 239
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
medulloblastoma 4 | 720
Amyotrophic lateral sclerosis 3 | 451
Asperger syndrome 3 | 37
Attention deficit hyperactivity disorder 3 | 278
Cancer 3 | 2,499
Cerebrovascular disease 3 | 238
Generalized anxiety disorder 3 | 29
Huntington's disease 3 | 76
Hyperekplexia 3 | 16
Multiple Sclerosis 3 | 540
Neuropathy 3 | 261
Obesity 3 | 678
Opiate dependence 3 | 29
Stiff-Person syndrome 3 | 12
Substance Withdrawal Syndrome 3 | 55
Substance abuse 3 | 59
Toxic encephalopathy 3 | 141
colon cancer 3 | 1,478
esophageal adenocarcinoma 3 | 737
lung adenocarcinoma 3 | 2,716
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
obsessive-compulsive disorder 3 | 61
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Acquired scoliosis 2 | 281
Autism Spectrum Disorders 2 | 75
Cannabis dependence 2 | 23
Curvature of spine 2 | 282
Epileptic encephalopathy 2 | 26
Heroin dependence 2 | 30
Hyperalgesia 2 | 83
Hyperreflexia 2 | 209
Infantile onset 2 | 238
Liver cancer 2 | 604
Muscle Hypertonia 2 | 88
Nerve Degeneration 2 | 121
Neurodegenerative disease 2 | 414
Nicotine dependence 2 | 54
Panic disorder 2 | 61
Psychotic Disorders 2 | 151
Succinic semialdehyde dehydrogenase deficiency 2 | 16
Tonic-clonic epilepsy 2 | 47
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
post-traumatic stress disorder 2 | 40
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Endocrine System 28 | 18,159
Nervous System 28 | 16,725
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Male tissues 26 | 17,142
Liver and Pancreas 25 | 16,750
Respiratory system 24 | 16,393
Urinary Tract 24 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 8 | 12,091
Transporter 7 | 473
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634

Compartment GO Term

GABA-ergic synapse 28 | 28
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycine--tRNA ligase GARS Tbio Enzyme -2.62899 412.8 178
Rho guanine nucleotide exchange factor 9 ARHGEF9 Tbio Non-IDG -1.48568 33.8 126
SLIT and NTRK-like protein 3 SLITRK3 Tbio Non-IDG -0.57320 3.62 79
Vesicular glutamate transporter 2 SLC17A6 Tbio Transporter -2.57663 372.2 154
Neuroligin-1 NLGN1 Tbio Enzyme -1.96626 95.1 225
Sodium- and chloride-dependent GABA transporter 3 SLC6A11 Tbio Transporter -2.26927 175.1 75
Tryptophan--tRNA ligase, cytoplasmic WARS Tbio Enzyme -2.74520 518.6 163
Neuroligin-2 NLGN2 Tbio Enzyme -1.71616 50.4 77
Brain-derived neurotrophic factor BDNF Tbio Non-IDG -4.00507 10701.6 723
Solute carrier family 12 member 5 SLC12A5 Tchem Transporter -2.58623 402.8 217