Development Level

Tbio 80 | 11,445
Tdark 35 | 6,588
Tchem 7 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal behavior 4 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased circulating glucose ... 2 | 24
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal forebrain development 1 | 20
abnormal hair growth 1 | 10
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
absent teeth 1 | 3
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged adrenal glands 1 | 3
enlarged pancreas 1 | 2
enlarged spleen 1 | 41
hydrometra 1 | 53
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating glycerol... 1 | 9
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
polydactyly 1 | 7
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 76 | 11,493
ovarian cancer 66 | 8,520
osteosarcoma 60 | 7,950
glioblastoma 49 | 5,792
medulloblastoma, large-cell 46 | 6,241
atypical teratoid / rhabdoid tumor 45 | 5,112
psoriasis 44 | 6,694
ependymoma 39 | 4,679
lung cancer 35 | 4,740
Astrocytoma, Pilocytic 34 | 3,081
Breast cancer 34 | 3,578
non-small cell lung cancer 31 | 2,890
adult high grade glioma 30 | 3,801
group 3 medulloblastoma 29 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
oligodendroglioma 28 | 2,850
Kidney cancer 26 | 2,613
pancreatic cancer 25 | 2,398
invasive ductal carcinoma 24 | 2,951
malignant mesothelioma 24 | 3,232
primitive neuroectodermal tumor 24 | 3,035
subependymal giant cell astrocytoma 24 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
Cancer 22 | 2,499
lung adenocarcinoma 20 | 2,716
pituitary cancer 20 | 1,972
interstitial cystitis 19 | 2,312
astrocytic glioma 18 | 2,597
astrocytoma 18 | 1,146
colon cancer 17 | 1,478
cystic fibrosis 17 | 1,696
group 4 medulloblastoma 17 | 1,855
lung carcinoma 17 | 2,843
Pick disease 16 | 1,894
adrenocortical carcinoma 16 | 1,428
ulcerative colitis 16 | 1,819
ductal carcinoma in situ 15 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
tuberculosis 15 | 2,010
Rheumatoid arthritis 13 | 1,191
breast carcinoma 13 | 1,638
dermatomyositis 13 | 966
active Crohn's disease 12 | 922
acute quadriplegic myopathy 12 | 1,158
spina bifida 12 | 1,074
Liver Cirrhosis, Experimental 11 | 769
diabetes mellitus 11 | 1,728
esophageal adenocarcinoma 11 | 737
gastric carcinoma 11 | 807
primary pancreatic ductal adenocarcinoma 11 | 1,109
juvenile dermatomyositis 10 | 1,187
pediatric high grade glioma 10 | 1,064
fibroadenoma 9 | 559
medulloblastoma 9 | 720
acute myeloid leukemia 8 | 783
Schizophrenia 7 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
gastric cancer 7 | 459
non primary Sjogren syndrome sicca 7 | 891
pancreatic carcinoma 7 | 562
Autosomal recessive predisposition 6 | 1,442
Down syndrome 6 | 499
Epilepsy 6 | 792
active ulcerative colitis 6 | 764
cutaneous lupus erythematosus 6 | 1,057
interstitial lung disease 6 | 298
nasopharyngeal carcinoma 6 | 1,058
primary Sjogren syndrome 6 | 735
Bipolar Disorder 5 | 666
COPD 5 | 118
Crohn's disease 5 | 321
Endometriosis 5 | 540
Leukemia, Myelocytic, Acute 5 | 120
posterior fossa group A ependymoma 5 | 468
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Atopic dermatitis 4 | 952
Cardiomyopathy, Dilated 4 | 83
Duchenne muscular dystrophy 4 | 601
Immune system cancer 4 | 140
Liver cancer 4 | 604
Lymphoid leukemia 4 | 160
Neoplasm Invasiveness 4 | 161
Osteoporosis 4 | 363
Peripheral Neuropathy 4 | 134
Polycystic ovary syndrome 4 | 360
Prostate cancer 4 | 175
Seizures 4 | 596
atypical teratoid/rhabdoid tumor 4 | 357
hereditary spastic paraplegia 4 | 318
non-small cell lung carcinoma 4 | 317
sonic hedgehog group medulloblastoma 4 | 467
tuberculosis and treatment for 6 months 4 | 409
urothelial carcinoma 4 | 318
Arthritis 3 | 290
Mental Depression 3 | 333
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
chronic rhinosinusitis 3 | 512

Tissue

Blood and immune system 124 | 16,909
Endocrine System 124 | 18,159
Female tissues 124 | 17,400
Respiratory system 124 | 16,393
Digestive Tract 123 | 17,369
Liver and Pancreas 123 | 16,750
Male tissues 123 | 17,142
Nervous System 123 | 16,725
Skin and soft tissues 123 | 17,230
Urinary Tract 123 | 16,678
Cardiovascular System 120 | 15,192

Target Family

Non-IDG 94 | 12,091
Enzyme 18 | 4,145
Transporter 5 | 473
Kinase 3 | 634
Ion Channel 2 | 344
Transcription Factor 2 | 1,400
GPCR 1 | 408

Compartment GO Term

Focal adhesion sites 125 | 125
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 ALKBH6 Tdark Enzyme 0.38 0.31 58
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Phospholipid-metabolizing enzyme A-C1 HRASLS Tbio Non-IDG -0.89072 8.53 0
Ras GTPase-activating protein nGAP RASAL2 Tbio Enzyme -1.51440 33.0 99
Talin-2 TLN2 Tbio Non-IDG -1.36153 20.0 101
LIM and SH3 domain protein 1 LASP1 Tbio Non-IDG -1.87137 77.5 299
Suppressor of IKBKE 1 SIKE1 Tdark Non-IDG -0.71713 4.66 97
Oligoribonuclease, mitochondrial REXO2 Tbio Enzyme -2.15502 143.8 115
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.26880 23.6 187
Exonuclease mut-7 homolog EXD3 Tdark Enzyme -0.45611 3.91 67