Development Level

Tbio 77 | 11,445
Tchem 8 | 1,598
Tdark 5 | 6,588
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 7 | 499
abnormal behavior 5 | 298
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal embryo turning 2 | 31
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
abnormal stomach morphology 2 | 10
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating alanine ... 2 | 47
decreased circulating serum al... 2 | 82
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased prepulse inhibition 2 | 32
pallor 2 | 34
small testis 2 | 58
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal digestive system phys... 1 | 1
abnormal digit morphology 1 | 10
abnormal femur morphology 1 | 14
abnormal hair growth 1 | 10
abnormal iris morphology 1 | 13
abnormal iris pigmentation 1 | 4
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
absent urinary bladder 1 | 1
absent vibrissae 1 | 12
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased mean platelet volume 1 | 25
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged kidney 1 | 14
female infertility 1 | 60
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
thin ventricular wall 1 | 24

Disease

Carcinoma 74 | 11,493
ovarian cancer 64 | 8,520
psoriasis 52 | 6,694
medulloblastoma, large-cell 51 | 6,241
osteosarcoma 51 | 7,950
glioblastoma 50 | 5,792
atypical teratoid / rhabdoid tumor 40 | 5,112
ependymoma 39 | 4,679
lung cancer 35 | 4,740
Breast cancer 33 | 3,578
Cancer 33 | 2,499
group 3 medulloblastoma 32 | 4,104
Astrocytoma, Pilocytic 30 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
adult high grade glioma 28 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
malignant mesothelioma 26 | 3,232
non-small cell lung cancer 25 | 2,890
lung carcinoma 24 | 2,843
pancreatic cancer 24 | 2,398
primitive neuroectodermal tumor 24 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
invasive ductal carcinoma 23 | 2,951
Kidney cancer 22 | 2,613
interstitial cystitis 20 | 2,312
astrocytic glioma 19 | 2,597
colon cancer 19 | 1,478
cystic fibrosis 19 | 1,696
acute quadriplegic myopathy 18 | 1,158
oligodendroglioma 18 | 2,850
diabetes mellitus 17 | 1,728
group 4 medulloblastoma 17 | 1,855
lung adenocarcinoma 17 | 2,716
subependymal giant cell astrocytoma 17 | 2,287
ductal carcinoma in situ 16 | 1,745
juvenile dermatomyositis 16 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
ulcerative colitis 16 | 1,819
tuberculosis 15 | 2,010
astrocytoma 14 | 1,146
breast carcinoma 14 | 1,638
pituitary cancer 12 | 1,972
Autosomal recessive predisposition 11 | 1,442
Duchenne muscular dystrophy 11 | 601
dermatomyositis 11 | 966
pediatric high grade glioma 11 | 1,064
Down syndrome 10 | 499
Liver Cirrhosis, Experimental 10 | 769
adrenocortical carcinoma 10 | 1,428
spina bifida 10 | 1,074
Liver cancer 9 | 604
Multiple myeloma 9 | 1,332
Pick disease 9 | 1,894
Rheumatoid arthritis 9 | 1,191
Schizophrenia 9 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
cutaneous lupus erythematosus 9 | 1,057
esophageal adenocarcinoma 9 | 737
gastric carcinoma 9 | 807
primary pancreatic ductal adenocarcinoma 9 | 1,109
Asthma 8 | 385
Muscle hypotonia 8 | 571
Myopathy 8 | 185
Neuropathy 8 | 261
nasopharyngeal carcinoma 8 | 1,058
Amyotrophic lateral sclerosis 7 | 451
Bipolar Disorder 7 | 666
Endometriosis 7 | 540
Intellectual disability 7 | 1,016
Nonsyndromic deafness 7 | 142
Big calvaria 6 | 147
Cardiomyopathy 6 | 116
Cardiomyopathy, Dilated 6 | 83
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Increased head circumference 6 | 147
Increased size of cranium 6 | 147
Increased size of skull 6 | 147
Mental Depression 6 | 333
Mental and motor retardation 6 | 608
active ulcerative colitis 6 | 764
aldosterone-producing adenoma 6 | 665
pancreatic carcinoma 6 | 562
primary Sjogren syndrome 6 | 735
Acquired scoliosis 5 | 281
Alzheimer's disease 5 | 658
Becker muscular dystrophy 5 | 191
Cerebrovascular disease 5 | 238
Chronic Lymphocytic Leukemia 5 | 262
Curvature of spine 5 | 282
Dull intelligence 5 | 645
Epilepsy 5 | 792
Heart disease 5 | 306
Kidney disease 5 | 430
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
Seizures 5 | 596
Vascular disease 5 | 319
chronic rhinosinusitis 5 | 512
mucosa-associated lymphoid tissue lymphoma 5 | 484

Tissue

Female tissues 93 | 17,400
Blood and immune system 92 | 16,909
Endocrine System 92 | 18,159
Digestive Tract 91 | 17,369
Male tissues 91 | 17,142
Respiratory system 91 | 16,393
Skin and soft tissues 91 | 17,230
Urinary Tract 91 | 16,678
Liver and Pancreas 90 | 16,750
Nervous System 89 | 16,725
Cardiovascular System 86 | 15,192

Target Family

Non-IDG 73 | 12,091
Enzyme 12 | 4,145
Kinase 4 | 634
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

Compartment GO Term

Filopodium 93 | 93
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
V-set and transmembrane domain-containing protein 5 VSTM5 Tdark Non-IDG -0.30103 2.00 19
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Adhesion G protein-coupled receptor A2 ADGRA2 Tbio GPCR -1.45203 30.0 211
Rho family-interacting cell polarization regulator 2 RIPOR2 Tbio Non-IDG -0.97707 10.8 109
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47