Development Level

Tbio 68 | 11,651
Tchem 9 | 1,388
Tclin 8 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
preweaning lethality, complete... 6 | 979
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
abnormal coat appearance 2 | 31
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating LDL chol... 2 | 38
decreased circulating serum al... 2 | 82
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal motor learning 1 | 3
abnormal retinal inner nuclear... 1 | 8
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
corneal opacity 1 | 32
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased spleen weight 1 | 10
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged kidney 1 | 14
female infertility 1 | 60
fused cornea and lens 1 | 5
hypoactivity 1 | 132
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased urine magnesium leve... 1 | 2
increased vertical activity 1 | 24
mammalian phenotype 1 | 17
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 64 | 11,493
ovarian cancer 60 | 8,520
Cancer 55 | 2,499
osteosarcoma 52 | 7,950
psoriasis 44 | 6,694
glioblastoma 39 | 5,792
atypical teratoid / rhabdoid tumor 37 | 5,112
ependymoma 36 | 4,679
lung cancer 32 | 4,740
medulloblastoma, large-cell 32 | 6,241
pancreatic cancer 32 | 2,398
Breast cancer 30 | 3,578
Astrocytoma, Pilocytic 28 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
lung adenocarcinoma 25 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
lung carcinoma 24 | 2,843
Kidney cancer 23 | 2,613
adult high grade glioma 23 | 3,801
primitive neuroectodermal tumor 23 | 3,035
ulcerative colitis 23 | 1,819
diabetes mellitus 22 | 1,728
invasive ductal carcinoma 22 | 2,951
subependymal giant cell astrocytoma 22 | 2,287
malignant mesothelioma 20 | 3,232
non-small cell lung cancer 20 | 2,890
Rheumatoid arthritis 19 | 1,191
astrocytic glioma 19 | 2,597
interstitial cystitis 19 | 2,312
oligodendroglioma 19 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
group 3 medulloblastoma 17 | 4,104
group 4 medulloblastoma 17 | 1,855
Liver Cirrhosis, Experimental 15 | 769
pituitary cancer 15 | 1,972
primary pancreatic ductal adenocarcinoma 15 | 1,109
colon cancer 14 | 1,478
tuberculosis 14 | 2,010
Heart disease 13 | 306
Osteoporosis 13 | 363
adrenocortical carcinoma 13 | 1,428
breast carcinoma 13 | 1,638
ductal carcinoma in situ 13 | 1,745
Alzheimer's disease 12 | 658
Kidney disease 12 | 430
Multiple myeloma 12 | 1,332
spina bifida 12 | 1,074
Schizophrenia 11 | 1,160
acute quadriplegic myopathy 11 | 1,158
juvenile dermatomyositis 11 | 1,187
pancreatic carcinoma 11 | 562
pediatric high grade glioma 11 | 1,064
Cerebrovascular disease 10 | 238
Hypertension 10 | 396
Neoplasm Invasiveness 10 | 161
gastric carcinoma 10 | 807
medulloblastoma 10 | 720
Breast Neoplasms 9 | 445
Duchenne muscular dystrophy 9 | 601
Pick disease 9 | 1,894
Vascular disease 9 | 319
cystic fibrosis 9 | 1,696
mucosa-associated lymphoid tissue lymphoma 9 | 484
Animal Mammary Neoplasms 8 | 136
Intellectual disability 8 | 1,016
Mammary Neoplasms 8 | 425
Mammary Neoplasms, Animal 8 | 136
Neurodegenerative disease 8 | 414
astrocytoma 8 | 1,146
dermatomyositis 8 | 966
Autosomal recessive predisposition 7 | 1,442
Bipolar Disorder 7 | 666
Down syndrome 7 | 499
Epilepsy 7 | 792
Inflammatory bowel disease 7 | 151
Mammary Neoplasms, Experimental 7 | 154
Multiple Sclerosis 7 | 540
Neoplasm Metastasis 7 | 168
Obesity 7 | 678
Prostatic Neoplasms 7 | 495
Stomach Neoplasms 7 | 300
Waldenstrons macroglobulinemia 7 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
esophageal adenocarcinoma 7 | 737
hepatocellular carcinoma 7 | 547
Becker muscular dystrophy 6 | 191
Dull intelligence 6 | 645
Low intelligence 6 | 645
Lung Neoplasms 6 | 232
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Polycystic ovary syndrome 6 | 360
Poor school performance 6 | 645
cutaneous lupus erythematosus 6 | 1,057
gastric cancer 6 | 459
nasopharyngeal carcinoma 6 | 1,058
periodontitis 6 | 293
sonic hedgehog group medulloblastoma 6 | 467
urothelial carcinoma 6 | 318

Tissue

Blood and immune system 84 | 16,909
Endocrine System 84 | 18,159
Female tissues 84 | 17,400
Liver and Pancreas 84 | 16,750
Male tissues 84 | 17,142
Respiratory system 84 | 16,393
Skin and soft tissues 84 | 17,230
Digestive Tract 83 | 17,369
Nervous System 82 | 16,725
Urinary Tract 82 | 16,678
Cardiovascular System 78 | 15,192

Target Family

Non-IDG 64 | 12,091
Enzyme 11 | 4,145
Kinase 9 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

Compartment GO Term

Filamentous actin 86 | 86
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Tropomodulin-1 TMOD1 Tbio Non-IDG -1.84485 74.1 155
Tropomodulin-4 TMOD4 Tbio Non-IDG -1.94209 70.0 114
Proto-oncogene vav VAV1 Tchem Non-IDG -2.66356 489.1 548
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.45823 27.6 148
Unconventional myosin-VI MYO6 Tbio Non-IDG -1.72509 54.2 108
LIM domain kinase 1 LIMK1 Tchem Kinase -2.28919 187.7 664
Wiskott-Aldrich syndrome protein WAS Tbio Non-IDG -3.10496 1242.1 320
Ras-related C3 botulinum toxin substrate 2 RAC2 Tbio Enzyme -2.89402 669.8 273