Development Level

Tbio 60 | 10,625
Tchem 12 | 1,890
Tclin 5 | 602
Tdark 5 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, incomple... 6 | 260
embryonic lethality prior to t... 4 | 187
decreased mean corpuscular vol... 3 | 50
abnormal embryo size 2 | 112
abnormal retina morphology 2 | 100
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
increased or absent threshold ... 2 | 128
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal motor learning 1 | 4
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal vertebrae morphology 1 | 14
absent pinna reflex 1 | 21
decreased NK T cell number 1 | 28
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased fasted circulating g... 1 | 49
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 34
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
female infertility 1 | 34
hydrops fetalis 1 | 22
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased heart rate 1 | 17
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased neutrophil cell numb... 1 | 15
increased red blood cell distr... 1 | 21
microphthalmia 1 | 15
prenatal lethality prior to he... 1 | 64
shortened RR interval 1 | 19

Disease

ovarian cancer 54 | 8,492
osteosarcoma 50 | 7,933
Cancer 48 | 2,346
psoriasis 39 | 6,685
glioblastoma 36 | 5,572
medulloblastoma, large-cell 32 | 6,234
atypical teratoid / rhabdoid tumor 30 | 4,369
pancreatic cancer 29 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
lung cancer 26 | 4,473
pilocytic astrocytoma 26 | 3,086
lung adenocarcinoma 25 | 2,714
Breast cancer 24 | 3,099
Carcinoma 24 | 2,147
primitive neuroectodermal tumor 23 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,956
lung carcinoma 22 | 2,844
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
pediatric high grade glioma 21 | 2,712
subependymal giant cell astrocytoma 20 | 2,287
invasive ductal carcinoma 19 | 2,950
ulcerative colitis 19 | 2,087
oligodendroglioma 18 | 2,849
diabetes mellitus 17 | 1,663
group 4 medulloblastoma 17 | 1,875
malignant mesothelioma 17 | 3,163
posterior fossa group A ependymoma 17 | 1,511
Rheumatoid Arthritis 16 | 1,171
pituitary cancer 16 | 1,972
colon cancer 15 | 1,475
interstitial cystitis 15 | 2,299
primary pancreatic ductal adenocarcinoma 15 | 1,271
tuberculosis 15 | 1,563
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
adrenocortical carcinoma 13 | 1,427
astrocytoma 13 | 1,493
ependymoma 13 | 2,514
medulloblastoma 13 | 1,524
non-small cell lung cancer 13 | 2,798
Multiple myeloma 12 | 1,328
adult high grade glioma 12 | 2,148
astrocytic glioma 12 | 2,241
posterior fossa group B ependymoma 12 | 1,530
spina bifida 12 | 1,064
Duchenne muscular dystrophy 11 | 602
Kidney disease 11 | 397
ductal carcinoma in situ 11 | 1,745
juvenile dermatomyositis 11 | 1,189
pancreatic carcinoma 11 | 567
Alzheimer's disease 10 | 644
Osteoporosis 10 | 259
sonic hedgehog group medulloblastoma 10 | 1,482
Neoplasm Invasiveness 9 | 127
Vascular disease 9 | 281
acute quadriplegic myopathy 9 | 1,157
Animal Mammary Neoplasms 8 | 136
Heart disease 8 | 279
Mammary Neoplasms 8 | 410
Neurodegenerative disease 8 | 383
atypical teratoid/rhabdoid tumor 8 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
breast carcinoma 8 | 1,614
cystic fibrosis 8 | 1,670
dermatomyositis 8 | 967
gastric carcinoma 8 | 832
group 3 medulloblastoma 8 | 2,254
mucosa-associated lymphoid tissue lymphoma 8 | 480
Down syndrome 7 | 548
hepatocellular carcinoma 7 | 550
Becker muscular dystrophy 6 | 187
Cerebrovascular disease 6 | 231
Hypertension 6 | 293
Inflammatory bowel disease 6 | 142
Mammary Neoplasms, Experimental 6 | 150
Nonsyndromic deafness 6 | 121
Pick disease 6 | 1,893
Prostatic Neoplasms 6 | 471
acute myeloid leukemia 6 | 785
esophageal adenocarcinoma 6 | 737
COPD 5 | 116
Cardiomyopathy 5 | 110
Intellectual disability 5 | 573
Liver carcinoma 5 | 217
Neoplasm Metastasis 5 | 138
Neurofibromatosis 5 | 37
Polycystic Ovary Syndrome 5 | 335
Squamous cell carcinoma 5 | 96
Waldenstrons macroglobulinemia 5 | 765
cutaneous lupus erythematosus 5 | 1,056
gastric cancer 5 | 436
urothelial carcinoma 5 | 318
Adenoma 4 | 165
Atopic dermatitis 4 | 944
Colorectal Neoplasms 4 | 217
Endometriosis 4 | 535
Epilepsy 4 | 346
Multiple Sclerosis 4 | 498
Myopathy 4 | 128
Stomach Neoplasms 4 | 282
nasopharyngeal carcinoma 4 | 1,056

Tissue

Blood and immune system 81 | 17,995
Cardiovascular System 81 | 17,958
Digestive Tract 81 | 18,473
Endocrine System 81 | 18,512
Female tissues 81 | 18,647
Liver and Pancreas 81 | 18,136
Male tissues 81 | 17,969
Nervous System 81 | 18,561
Respiratory system 81 | 17,484
Urinary Tract 81 | 18,444
Skin and soft tissues 80 | 18,115

Target Family

Non-IDG 63 | 11,969
Enzyme 9 | 4,146
Kinase 9 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Filamentous actin 82 | 82
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Wiskott-Aldrich syndrome protein WAS Tbio Non-IDG -3.08376 1138.7 279
Ras-related C3 botulinum toxin substrate 2 RAC2 Tchem Enzyme -2.87547 633.7 216
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.59105 344.4 405
Paxillin PXN Tchem Non-IDG -2.97313 849.9 1088
Thymosin beta-15A TMSB15B Tdark Non-IDG -0.93212 18.6 34
Thymosin beta-15B TMSB15B Tdark Non-IDG -0.93212 18.6 8
Myristoylated alanine-rich C-kinase substrate MARCKS Tbio Enzyme -2.67051 512.2 639
LIM domain kinase 1 LIMK1 Tchem Kinase -2.25846 175.4 612
Ezrin EZR Tbio Non-IDG -2.98006 942.2 903
Moesin MSN Tbio Non-IDG -2.59079 339.5 426