Development Level

Tbio 104 | 10,625
Tchem 39 | 1,890
Tclin 15 | 602
Tdark 5 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117

IMPC Term

abnormal behavior 6 | 226
abnormal bone mineralization 6 | 55
preweaning lethality, complete... 6 | 633
abnormal bone structure 5 | 131
decreased bone mineral content 5 | 157
increased heart weight 4 | 37
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased hematocrit 3 | 36
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
abnormal spleen morphology 2 | 36
decreased circulating HDL chol... 2 | 77
decreased circulating calcium ... 2 | 33
decreased circulating choleste... 2 | 85
decreased circulating phosphat... 2 | 15
decreased fasted circulating g... 2 | 49
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
enlarged spleen 2 | 26
hyperactivity 2 | 108
impaired righting response 2 | 19
increased CD4-positive, alpha ... 2 | 15
increased bone mineral content 2 | 92
increased circulating phosphat... 2 | 24
increased lean body mass 2 | 107
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
cataract 1 | 26
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, alpha-... 1 | 26
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased coping response 1 | 5
decreased dendritic cell numbe... 1 | 3
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased immature NK cell num... 1 | 1
decreased kidney weight 1 | 7
decreased mature B cell number 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
edema 1 | 11
enlarged seminal vesicle 1 | 1
increased KLRG1-positive NK ce... 1 | 9
increased Ly6C high monocyte n... 1 | 12
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mature NK cell numbe... 1 | 1
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased plasmacytoid dendrit... 1 | 1
increased respiratory quotient 1 | 12
male infertility 1 | 62
prenatal lethality 1 | 16
small testis 1 | 37
tremors 1 | 34
vertebral fusion 1 | 23

Disease

ovarian cancer 94 | 8,484
osteosarcoma 91 | 7,933
medulloblastoma, large-cell 79 | 6,234
Cancer 72 | 2,346
glioblastoma 64 | 5,572
psoriasis 63 | 6,685
atypical teratoid / rhabdoid tumor 56 | 4,369
lung cancer 50 | 4,466
Carcinoma 47 | 2,147
pilocytic astrocytoma 47 | 3,086
oligodendroglioma 46 | 2,849
pancreatic cancer 46 | 2,300
lung carcinoma 44 | 2,844
invasive ductal carcinoma 41 | 2,950
subependymal giant cell astrocytoma 40 | 2,287
interstitial cystitis 39 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,289
non-small cell lung cancer 38 | 2,798
primitive neuroectodermal tumor 38 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
ulcerative colitis 36 | 2,087
lung adenocarcinoma 34 | 2,713
Breast cancer 33 | 3,094
malignant mesothelioma 32 | 3,162
pediatric high grade glioma 32 | 2,712
ependymoma 31 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,956
pituitary cancer 31 | 1,972
ductal carcinoma in situ 30 | 1,745
group 4 medulloblastoma 29 | 1,875
adult high grade glioma 27 | 2,148
Pick disease 24 | 1,893
astrocytoma 24 | 1,493
diabetes mellitus 24 | 1,663
medulloblastoma 24 | 1,524
astrocytic glioma 23 | 2,241
juvenile dermatomyositis 23 | 1,189
posterior fossa group A ependymoma 23 | 1,511
tuberculosis 23 | 1,557
Rheumatoid Arthritis 22 | 1,160
colon cancer 22 | 1,475
primary pancreatic ductal adenocarcinoma 21 | 1,271
cystic fibrosis 20 | 1,665
group 3 medulloblastoma 20 | 2,254
primary Sjogren syndrome 20 | 789
Blastic phase chronic myeloid leukemia 18 | 58
Chronic Myelocytic Leukemia Accelerated Phase 18 | 59
breast carcinoma 18 | 1,614
acute quadriplegic myopathy 17 | 1,157
posterior fossa group B ependymoma 17 | 1,530
Chronic phase chronic myeloid leukemia 16 | 45
Kidney disease 16 | 396
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 16 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 16 | 47
cutaneous lupus erythematosus 16 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
spina bifida 16 | 1,064
Alzheimer's disease 14 | 644
Duchenne muscular dystrophy 14 | 602
Obesity 13 | 616
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
dermatomyositis 13 | 933
esophageal adenocarcinoma 13 | 737
non primary Sjogren syndrome sicca 13 | 840
Adenoma 12 | 165
Multiple myeloma 12 | 1,327
gastric carcinoma 12 | 832
urothelial carcinoma 12 | 318
Down syndrome 11 | 548
Mammary Neoplasms 11 | 410
Schizophrenia 11 | 501
Waldenstrons macroglobulinemia 11 | 765
adrenocortical carcinoma 11 | 1,427
atypical teratoid/rhabdoid tumor 11 | 1,095
mucosa-associated lymphoid tissue lymphoma 11 | 480
Atopic dermatitis 10 | 944
Hypertension 10 | 287
Intellectual disability 10 | 573
Prostatic Neoplasms 10 | 471
pancreatic carcinoma 10 | 567
Amyotrophic Lateral Sclerosis 9 | 431
Endometriosis 9 | 535
IGA Glomerulonephritis 9 | 454
Cerebrovascular disease 8 | 231
Crohn's disease 8 | 304
Hypertensive disease 8 | 193
Kidney cancer 8 | 118
Multiple Sclerosis 8 | 498
Stomach Neoplasms 8 | 282
active Crohn's disease 8 | 918
sarcoidosis 8 | 358
sonic hedgehog group medulloblastoma 8 | 1,482
Asthma 7 | 349
Lung disease 7 | 132
acute myeloid leukemia 7 | 780
chronic lymphosyte leukemia 7 | 232
fibroadenoma 7 | 557
nasopharyngeal carcinoma 7 | 1,056
nephrosclerosis 7 | 329
periodontitis 7 | 269

Tissue

Blood and immune system 160 | 17,995
Cardiovascular System 160 | 17,958
Digestive Tract 160 | 18,473
Endocrine System 160 | 18,512
Female tissues 160 | 18,647
Nervous System 160 | 18,561
Urinary Tract 160 | 18,444
Liver and Pancreas 159 | 18,136
Male tissues 159 | 17,969
Respiratory system 158 | 17,484
Skin and soft tissues 158 | 18,115

Target Family

Non-IDG 102 | 11,971
Kinase 37 | 634
Enzyme 17 | 4,146
Ion Channel 3 | 341
Epigenetic 1 | 242
GPCR 1 | 406
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

Compartment GO Term

Extrinsic component of plasma ... 163 | 163
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
Rho guanine nucleotide exchange factor 11 ARHGEF11 Tbio Non-IDG -1.54485 39.7 163
Signal peptide, CUB and EGF-like domain-containing protein 1 SCUBE1 Tbio Non-IDG -1.25952 24.9 65
Protein-tyrosine kinase 6 PTK6 Tchem Kinase -2.14303 167.1 320
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
G-protein-signaling modulator 1 GPSM1 Tbio Non-IDG -1.32467 28.6 99
Guanine nucleotide exchange factor DBS MCF2L Tbio Non-IDG -0.93602 11.4 104
Regulator of G-protein signaling 16 RGS16 Tbio Non-IDG -1.59717 42.2 162