Development Level

Tbio 20 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal vertebrae morphology 1 | 18
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased pulmonary respirator... 1 | 5
embryonic lethality prior to o... 1 | 239
impaired glucose tolerance 1 | 75
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased hematocrit 1 | 46
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 15 | 11,493
ovarian cancer 12 | 8,520
osteosarcoma 9 | 7,950
psoriasis 8 | 6,694
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
atypical teratoid / rhabdoid tumor 6 | 5,112
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
adult high grade glioma 4 | 3,801
cystic fibrosis 4 | 1,696
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
ulcerative colitis 4 | 1,819
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Failure to gain weight 3 | 365
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
astrocytic glioma 3 | 2,597
gastric carcinoma 3 | 807
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
medulloblastoma 3 | 720
oligodendroglioma 3 | 2,850
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Anteverted nostril 2 | 191
Big calvaria 2 | 147
Breast cancer 2 | 3,578
Cerebellar Ataxia 2 | 304
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Esophageal Squamous Cell Carcinoma 2 | 77
Frequent fractures 2 | 53
Frontal bossing 2 | 157
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Hypertensive disease 2 | 292
Increased fracture rate 2 | 53
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Liver Cirrhosis, Experimental 2 | 769
Low Vision 2 | 174
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Narrow thorax 2 | 53
Neoplasm Metastasis 2 | 168
Nystagmus 2 | 317
Optic Atrophy 2 | 242
Pancreatic Neuroendocrine Tumor 2 | 45
Prostatic Neoplasms 2 | 495
Renal Cell Carcinoma 2 | 214
Round face 2 | 45
Round, full face 2 | 45
Schizophrenia 2 | 1,160
Short stature 2 | 531
Squamous cell carcinoma of esophagus 2 | 77
Tremor 2 | 113
Usher syndrome type 1 2 | 10
Varying degree of multiple fractures 2 | 53
Visual Impairment 2 | 174
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
inflammatory breast cancer 2 | 286
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Acne 1 | 52
Acquired flat foot 1 | 72
Carcinoma of breast 1 | 11
Dermatitis herpetiformis 1 | 12
Flatfoot 1 | 73
Hyperkyphosis 1 | 111
Hypokalemia 1 | 52
Immunoglobulin alpha deficiency 1 | 11
Kyphosis deformity of spine 1 | 114
Liver Neoplasms, Experimental 1 | 59
Lordosis 1 | 54
Lysosomal storage disease 1 | 10
Menorrhagia 1 | 25
Organic writer's cramp 1 | 10
Short ribs 1 | 30

Tissue

Blood and immune system 24 | 16,909
Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678
Endocrine System 23 | 18,159
Nervous System 23 | 16,725

Target Family

Non-IDG 15 | 12,091
Enzyme 8 | 4,145
Kinase 1 | 634

Compartment GO Term

Extrinsic component of organel... 24 | 24
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein PML PML Tbio Non-IDG -2.63785 373.8 470
Annexin A1 ANXA1 Tbio Non-IDG -2.90864 897.0 765
Peptidyl-prolyl cis-trans isomerase FKBP1A FKBP1A Tclin Enzyme -2.77923 382.8 271
Serine/threonine-protein kinase ULK1 ULK1 Tchem Kinase -2.57033 346.8 647
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Torsin-1A TOR1A Tbio Non-IDG -3.10052 1230.7 179
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tbio Enzyme -1.72968 58.3 209
Golgin subfamily A member 3 GOLGA3 Tbio Non-IDG -1.33499 21.1 140
Sorting nexin-10 SNX10 Tbio Non-IDG -1.13183 16.8 72