Development Level

Tbio 166 | 10,625
Tchem 98 | 1,890
Tclin 33 | 602
Tdark 19 | 7,003

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 17 | 633
decreased body weight 8 | 174
abnormal bone mineralization 6 | 55
preweaning lethality, incomple... 5 | 260
abnormal behavior 4 | 226
abnormal bone structure 4 | 131
abnormal embryo size 4 | 112
decreased bone mineral content 4 | 157
decreased bone mineral density 4 | 126
decreased grip strength 4 | 123
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 4 | 187
increased heart weight 4 | 37
decreased circulating LDL chol... 3 | 37
decreased circulating choleste... 3 | 85
decreased circulating creatini... 3 | 31
decreased hemoglobin content 3 | 53
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
increased or absent threshold ... 3 | 128
male infertility 3 | 62
abnormal neural tube closure 2 | 37
abnormal retina morphology 2 | 100
decreased NK T cell number 2 | 28
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating triglyce... 2 | 83
decreased fasted circulating g... 2 | 49
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
decreased startle reflex 2 | 48
increased blood urea nitrogen ... 2 | 44
increased circulating LDL chol... 2 | 15
increased circulating alkaline... 2 | 119
increased circulating phosphat... 2 | 24
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal eye morphology 1 | 38
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 30
abnormal respiratory quotient 1 | 9
abnormal retinal inner nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
decreased CD8-positive, alpha-... 1 | 26
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating calcium ... 1 | 33
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased red blood cell distr... 1 | 11
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased respiratory quotient 1 | 12
limb grasping 1 | 35
microphthalmia 1 | 15
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened ST segment 1 | 9
small testis 1 | 37
thrombocytosis 1 | 23
tremors 1 | 34

Disease

ovarian cancer 194 | 8,484
osteosarcoma 171 | 7,933
Cancer 165 | 2,346
medulloblastoma, large-cell 141 | 6,234
psoriasis 141 | 6,685
glioblastoma 132 | 5,572
lung cancer 115 | 4,466
atypical teratoid / rhabdoid tumor 110 | 4,369
invasive ductal carcinoma 86 | 2,950
Carcinoma 85 | 2,147
intraductal papillary-mucinous neoplasm (IPMN) 83 | 3,289
pilocytic astrocytoma 82 | 3,086
diabetes mellitus 80 | 1,663
Breast cancer 78 | 3,094
oligodendroglioma 78 | 2,849
pancreatic cancer 77 | 2,300
ulcerative colitis 76 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 75 | 2,988
lung carcinoma 75 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 72 | 2,956
non-small cell lung cancer 71 | 2,798
interstitial cystitis 70 | 2,299
malignant mesothelioma 69 | 3,162
primitive neuroectodermal tumor 69 | 3,031
subependymal giant cell astrocytoma 69 | 2,287
ependymoma 65 | 2,514
pediatric high grade glioma 65 | 2,712
lung adenocarcinoma 64 | 2,713
ductal carcinoma in situ 56 | 1,745
group 4 medulloblastoma 54 | 1,875
Pick disease 51 | 1,893
adult high grade glioma 51 | 2,148
astrocytic glioma 51 | 2,241
Kidney disease 50 | 396
Obesity 50 | 616
astrocytoma 50 | 1,493
Alzheimer's disease 49 | 644
cystic fibrosis 49 | 1,665
medulloblastoma 49 | 1,524
pituitary cancer 49 | 1,972
Mammary Neoplasms 48 | 410
breast carcinoma 48 | 1,614
Prostatic Neoplasms 46 | 471
Rheumatoid Arthritis 46 | 1,160
tuberculosis 46 | 1,557
juvenile dermatomyositis 44 | 1,189
acute quadriplegic myopathy 42 | 1,157
pancreatic ductal adenocarcinoma liver metastasis 41 | 1,795
Stomach Neoplasms 40 | 282
posterior fossa group A ependymoma 40 | 1,511
colon cancer 38 | 1,475
Liver carcinoma 35 | 217
primary pancreatic ductal adenocarcinoma 35 | 1,271
Heart disease 34 | 279
Vascular disease 34 | 281
Multiple myeloma 33 | 1,327
group 3 medulloblastoma 32 | 2,254
Cerebrovascular disease 31 | 231
Hypertension 31 | 287
Lung Neoplasms 31 | 171
Adenoma 30 | 165
Arthritis 30 | 248
Neoplasm Metastasis 30 | 138
Parkinson's disease 30 | 364
Schizophrenia 30 | 501
Atherosclerosis 29 | 275
Liver disease 29 | 219
adrenocortical carcinoma 29 | 1,427
dermatomyositis 29 | 933
primary Sjogren syndrome 29 | 789
Neoplasm Invasiveness 28 | 127
Toxic encephalopathy 28 | 131
Asthma 27 | 349
Lung disease 27 | 132
Multiple Sclerosis 26 | 498
cutaneous lupus erythematosus 26 | 1,056
Atopic dermatitis 25 | 944
Endometriosis 25 | 535
Hypertensive disease 25 | 193
Adenocarcinoma 24 | 115
Coronary artery disease 24 | 240
Amyotrophic Lateral Sclerosis 23 | 431
Down syndrome 23 | 548
Hyperglycemia 23 | 120
acute myeloid leukemia 23 | 780
posterior fossa group B ependymoma 23 | 1,530
sonic hedgehog group medulloblastoma 23 | 1,482
spina bifida 23 | 1,064
Duchenne muscular dystrophy 22 | 602
Squamous cell carcinoma 22 | 94
autosomal dominant Emery-Dreifuss muscular dystrophy 22 | 499
esophageal adenocarcinoma 22 | 737
fibroadenoma 22 | 557
mucosa-associated lymphoid tissue lymphoma 22 | 480
non-small cell lung carcinoma 22 | 413
Brain disease 21 | 83
Colonic Neoplasms 21 | 126
Inflammation 21 | 109
nasopharyngeal carcinoma 21 | 1,056
pancreatic carcinoma 21 | 567

Tissue

Blood and immune system 311 | 17,995
Digestive Tract 311 | 18,473
Endocrine System 311 | 18,512
Female tissues 311 | 18,647
Nervous System 311 | 18,561
Urinary Tract 311 | 18,444
Cardiovascular System 310 | 17,958
Liver and Pancreas 310 | 18,136
Male tissues 308 | 17,969
Skin and soft tissues 308 | 18,115
Respiratory system 306 | 17,484

Target Family

Non-IDG 173 | 11,971
Kinase 71 | 634
Enzyme 51 | 4,146
Transcription Factor 11 | 1,400
Ion Channel 3 | 341
Nuclear Receptor 3 | 48
Epigenetic 2 | 242
GPCR 1 | 406
Transporter 1 | 473

Compartment GO Term

Extrinsic component of membran... 316 | 316
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Signal peptide, CUB and EGF-like domain-containing protein 1 SCUBE1 Tbio Non-IDG -1.25952 24.9 65
Protein-tyrosine kinase 6 PTK6 Tchem Kinase -2.14303 167.1 320
Golgin subfamily A member 3 GOLGA3 Tbio Non-IDG -1.29668 20.3 130