Development Level

Tbio 7 | 11,445

IMPC Phenotype

abnormal vertebrae morphology 1 | 18
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
increased hematocrit 1 | 46
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
ovarian cancer 5 | 8,520
ependymoma 4 | 4,679
medulloblastoma, large-cell 4 | 6,241
atypical teratoid / rhabdoid tumor 3 | 5,112
gastric carcinoma 3 | 807
invasive ductal carcinoma 3 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Breast cancer 2 | 3,578
Failure to gain weight 2 | 365
Frequent fractures 2 | 53
Hypertensive disease 2 | 292
Increased fracture rate 2 | 53
Pediatric failure to thrive 2 | 365
Usher syndrome type 1 2 | 10
Varying degree of multiple fractures 2 | 53
chronic lymphosyte leukemia 2 | 204
cystic fibrosis 2 | 1,696
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
primary Sjogren syndrome 2 | 735
ulcerative colitis 2 | 1,819
Abnormal blistering of the skin 1 | 54
Abnormal visual evoked potential 1 | 26
Abnormality of epiphysis morphology 1 | 39
Abnormality of hair consistency 1 | 5
Abnormality of hair curl pattern 1 | 5
Abnormality of hair texture 1 | 5
Abnormality of hair volume 1 | 5
Abnormality of the metaphyses 1 | 48
Abnormality of the ribs 1 | 32
Acquired metabolic disease 1 | 336
Adenocarcinoma of lung 1 | 142
Animal Mammary Neoplasms 1 | 136
Anxiety 1 | 136
Anxiety disease 1 | 113
Autosomal recessive malignant osteopetrosis 1 | 4
Bell Palsy 1 | 58
Big calvaria 1 | 147
Blister of skin 1 | 54
Body Temperature Changes 1 | 10
Bone pain 1 | 42
Cardiovascular system disease 1 | 246
Chronic rhinitis 1 | 7
Compression of optic nerve 1 | 7
Congenital deafness 1 | 185
Craniofacial Abnormalities 1 | 151
Deafness 1 | 198
Decreased bone mineral density Z score 1 | 31
Decreased platelet count 1 | 111
Disease of anatomical entity 1 | 32
Ecchymosis 1 | 66
Esophageal Squamous Cell Carcinoma 1 | 77
Facial Paresis 1 | 59
Facial muscle weakness of muscles innervated by CN VII 1 | 58
Fatigue 1 | 182
Frontal bossing 1 | 157
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hearing Loss, Partial 1 | 185
Immunologic Deficiency Syndromes 1 | 113
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Increased tendency to bruise 1 | 66
Infantile malignant osteopetrosis 1 | 4
Kidney Diseases 1 | 114
Late tooth eruption 1 | 61
Lymphadenopathy 1 | 62
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Narrow thorax 1 | 53
Neoplasm Metastasis 1 | 168
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 8 1 | 1
Opsoclonus 1 | 5
Osteopetrosis 1 | 43
Osteoporosis 1 | 363
Otitis Media 1 | 52
Pallor 1 | 40
Poor growth 1 | 114
Poor temperature regulation 1 | 10
Precocious exfoliation of primary tooth 1 | 11
Recurrent respiratory infections 1 | 141
Skin bulla 1 | 54
Skull malformation 1 | 38
Squamous cell carcinoma 1 | 129
Squamous cell carcinoma of esophagus 1 | 77
Thin skin 1 | 47
Thrombocytopenia 1 | 197
Tremor 1 | 113
Very poor growth 1 | 114
Visual Impairment 1 | 174
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hearing impairment 1 | 199

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 1 | 4,145

Compartment GO Term

Extrinsic component of endosom... 7 | 7
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-10 SNX10 Tbio Non-IDG -1.13183 16.8 72
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
WD repeat-containing protein 91 WDR91 Tbio Non-IDG -0.72903 5.46 54
WD repeat-containing protein 81 WDR81 Tbio Non-IDG -1.27329 20.6 5
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tbio Enzyme -1.72968 58.3 209
Annexin A1 ANXA1 Tbio Non-IDG -2.90864 897.0 765
Sorting nexin-16 SNX16 Tbio Non-IDG -0.69702 6.12 92