Development Level

Tbio 96 | 11,651
Tchem 29 | 1,388
Tclin 14 | 612
Tdark 2 | 6,593

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 8 | 499
increased startle reflex 7 | 112
abnormal bone structure 6 | 187
abnormal behavior 5 | 298
hypoactivity 5 | 132
decreased lymphocyte cell numb... 4 | 83
increased heart weight 4 | 62
increased monocyte cell number 4 | 63
abnormal seminal vesicle morph... 3 | 114
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased total body fat amoun... 3 | 207
increased neutrophil cell numb... 3 | 46
short tibia 3 | 97
thrombocytopenia 3 | 56
abnormal retina morphology 2 | 71
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating phosphat... 2 | 27
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
increased circulating alkaline... 2 | 122
increased circulating phosphat... 2 | 26
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal retinal inner nuclear... 1 | 8
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased total retina thickne... 1 | 4
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 108 | 11,493
osteosarcoma 85 | 7,950
ovarian cancer 81 | 8,520
medulloblastoma, large-cell 71 | 6,241
glioblastoma 63 | 5,792
Cancer 58 | 2,499
psoriasis 53 | 6,694
atypical teratoid / rhabdoid tumor 52 | 5,112
ependymoma 50 | 4,679
lung cancer 47 | 4,740
adult high grade glioma 42 | 3,801
Astrocytoma, Pilocytic 41 | 3,081
lung carcinoma 40 | 2,843
group 3 medulloblastoma 38 | 4,104
oligodendroglioma 38 | 2,850
Breast cancer 36 | 3,578
Kidney cancer 36 | 2,613
invasive ductal carcinoma 35 | 2,951
non-small cell lung cancer 35 | 2,890
subependymal giant cell astrocytoma 35 | 2,287
pancreatic cancer 33 | 2,398
primitive neuroectodermal tumor 32 | 3,035
interstitial cystitis 30 | 2,312
ulcerative colitis 30 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
malignant mesothelioma 29 | 3,232
tuberculosis 26 | 2,010
astrocytic glioma 25 | 2,597
group 4 medulloblastoma 25 | 1,855
Pick disease 23 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
lung adenocarcinoma 23 | 2,716
pituitary cancer 22 | 1,972
ductal carcinoma in situ 20 | 1,745
breast carcinoma 19 | 1,638
colon cancer 19 | 1,478
juvenile dermatomyositis 19 | 1,187
Blastic phase chronic myeloid leukemia 18 | 58
Chronic Myelocytic Leukemia Accelerated Phase 18 | 59
Rheumatoid arthritis 18 | 1,191
Schizophrenia 18 | 1,160
primary Sjogren syndrome 18 | 735
Liver Cirrhosis, Experimental 17 | 769
Chronic phase chronic myeloid leukemia 16 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 16 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 16 | 47
astrocytoma 16 | 1,146
diabetes mellitus 16 | 1,728
Obesity 15 | 678
Intellectual disability 14 | 1,016
cutaneous lupus erythematosus 14 | 1,057
cystic fibrosis 14 | 1,696
Autosomal recessive predisposition 12 | 1,442
acute quadriplegic myopathy 12 | 1,158
pediatric high grade glioma 12 | 1,064
primary pancreatic ductal adenocarcinoma 12 | 1,109
Atopic dermatitis 11 | 952
Melanoma 11 | 711
Multiple myeloma 11 | 1,332
adrenocortical carcinoma 11 | 1,428
spina bifida 11 | 1,074
Bipolar Disorder 10 | 666
Depressive disorder 10 | 409
Epilepsy 10 | 792
Hypertension 10 | 396
Kidney disease 10 | 430
Liver cancer 10 | 604
dermatomyositis 10 | 966
pancreatic carcinoma 10 | 562
Alzheimer's disease 9 | 658
Asthma 9 | 385
Chronic Lymphocytic Leukemia 9 | 262
Duchenne muscular dystrophy 9 | 601
Polycystic ovary syndrome 9 | 360
Skin cancer 9 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
mucosa-associated lymphoid tissue lymphoma 9 | 484
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Crohn's disease 8 | 321
Stomach Neoplasms 8 | 300
Waldenstrons macroglobulinemia 8 | 765
active ulcerative colitis 8 | 764
esophageal adenocarcinoma 8 | 737
non primary Sjogren syndrome sicca 8 | 891
Anemia 7 | 365
Down syndrome 7 | 499
Dull intelligence 7 | 645
Endometriosis 7 | 540
Immune system cancer 7 | 140
Low intelligence 7 | 645
Lymphoid leukemia 7 | 160
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Pseudohypoparathyroidism 7 | 18
Seizures 7 | 596
active Crohn's disease 7 | 922
urothelial carcinoma 7 | 318
Arthritis, Rheumatoid 6 | 174

Tissue

Endocrine System 137 | 18,159
Skin and soft tissues 135 | 17,230
Blood and immune system 134 | 16,909
Digestive Tract 134 | 17,369
Female tissues 134 | 17,400
Male tissues 133 | 17,142
Nervous System 132 | 16,725
Liver and Pancreas 131 | 16,750
Respiratory system 130 | 16,393
Urinary Tract 130 | 16,678
Cardiovascular System 127 | 15,192

Target Family

Non-IDG 85 | 12,091
Kinase 37 | 634
Enzyme 13 | 4,145
GPCR 3 | 408
Ion Channel 3 | 344

Compartment GO Term

Extrinsic component of cytopla... 141 | 141
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosducin PDC Tbio Non-IDG -2.36871 242.5 78
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
G-protein coupled receptor 176 GPR176 Tbio GPCR -2.38327 235.4 133
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.14835 1437.4 1136
Tyrosine-protein kinase JAK3 JAK3 Tclin Kinase -2.64385 453.7 292
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 GNB3 Tbio Non-IDG -2.34836 235.8 161
Sorting nexin-9 SNX9 Tbio Non-IDG -2.00279 102.8 241
Guanine nucleotide-binding protein subunit alpha-15 GNA15 Tbio Non-IDG -2.75089 487.7 170