Development Level

Tbio 83 | 11,445
Tchem 25 | 1,598
Tclin 15 | 613
Tdark 5 | 6,588

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
embryonic growth retardation 3 | 106
hyperactivity 3 | 148
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased circulating insulin ... 2 | 76
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
prenatal lethality prior to he... 2 | 87
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal clavicle morphology 1 | 6
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
absent spleen 1 | 3
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating total pr... 1 | 49
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased cardiac muscle contr... 1 | 8
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
prolonged ST segment 1 | 36

Disease

Carcinoma 83 | 11,493
ovarian cancer 68 | 8,520
osteosarcoma 63 | 7,950
Cancer 61 | 2,499
psoriasis 53 | 6,694
glioblastoma 52 | 5,792
ependymoma 42 | 4,679
lung cancer 39 | 4,740
medulloblastoma, large-cell 39 | 6,241
Breast cancer 35 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
malignant mesothelioma 33 | 3,232
pancreatic cancer 33 | 2,398
Astrocytoma, Pilocytic 32 | 3,081
Autosomal recessive predisposition 32 | 1,442
atypical teratoid / rhabdoid tumor 32 | 5,112
diabetes mellitus 32 | 1,728
lung carcinoma 32 | 2,843
Kidney disease 31 | 430
adult high grade glioma 31 | 3,801
invasive ductal carcinoma 31 | 2,951
non-small cell lung cancer 30 | 2,890
interstitial cystitis 29 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
lung adenocarcinoma 29 | 2,716
group 3 medulloblastoma 28 | 4,104
tuberculosis 28 | 2,010
ulcerative colitis 28 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
breast carcinoma 24 | 1,638
cystic fibrosis 24 | 1,696
Hypertension 23 | 396
subependymal giant cell astrocytoma 23 | 2,287
astrocytic glioma 22 | 2,597
oligodendroglioma 22 | 2,850
Prostatic Neoplasms 20 | 495
Anemia 19 | 365
Hypersensitivity reaction type II disease 19 | 253
Kidney cancer 19 | 2,613
Obesity 19 | 678
Heart disease 18 | 306
Hypertensive disease 18 | 292
Liver Cirrhosis, Experimental 18 | 769
Multiple myeloma 18 | 1,332
Schizophrenia 17 | 1,160
Vascular disease 17 | 319
pituitary cancer 17 | 1,972
Atherosclerosis 16 | 291
Toxic encephalopathy 16 | 141
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Alzheimer's disease 15 | 658
Diarrhea 15 | 253
Liver disease 15 | 237
acute quadriplegic myopathy 15 | 1,158
ductal carcinoma in situ 15 | 1,745
juvenile dermatomyositis 15 | 1,187
nasopharyngeal carcinoma 15 | 1,058
primary pancreatic ductal adenocarcinoma 15 | 1,109
Arthritis 14 | 290
Breast Neoplasms 14 | 445
Cerebrovascular disease 14 | 238
Pick disease 14 | 1,894
Stomach Neoplasms 14 | 300
cutaneous lupus erythematosus 14 | 1,057
dermatomyositis 14 | 966
Asthma 13 | 385
Brain Ischemia 13 | 110
Brain disease 13 | 96
Coronary artery disease 13 | 268
Endometriosis 13 | 540
Inflammatory bowel disease 13 | 151
Intellectual disability 13 | 1,016
Mammary Neoplasms 13 | 425
esophageal adenocarcinoma 13 | 737
spina bifida 13 | 1,074
Bipolar Disorder 12 | 666
Edema 12 | 81
Epilepsy 12 | 792
Hyperglycemia 12 | 137
Lung Neoplasms 12 | 232
Lung disease 12 | 142
Neurodegenerative disease 12 | 414
Seizures 12 | 596
Waldenstrons macroglobulinemia 12 | 765
gastric carcinoma 12 | 807
primitive neuroectodermal tumor 12 | 3,035
Atopic dermatitis 11 | 952
Diabetes Mellitus, Experimental 11 | 108
Duchenne muscular dystrophy 11 | 601
Major Depressive Disorder 11 | 301
Osteoporosis 11 | 363
Parkinson's disease 11 | 392
Thrombocytopenia 11 | 197
Vasculitis 11 | 80
interstitial lung disease 11 | 298
Cognitive delay 10 | 608
Failure to gain weight 10 | 365
Mental and motor retardation 10 | 608
Rheumatoid arthritis 10 | 1,191
colon cancer 10 | 1,478

Tissue

Digestive Tract 127 | 17,369
Endocrine System 125 | 18,159
Male tissues 125 | 17,142
Female tissues 124 | 17,400
Nervous System 124 | 16,725
Liver and Pancreas 123 | 16,750
Urinary Tract 123 | 16,678
Blood and immune system 122 | 16,909
Respiratory system 120 | 16,393
Skin and soft tissues 120 | 17,230
Cardiovascular System 109 | 15,192

Target Family

Non-IDG 75 | 12,091
Enzyme 40 | 4,145
Transporter 5 | 473
Ion Channel 4 | 344
Transcription Factor 2 | 1,400
GPCR 1 | 408
Kinase 1 | 634

Compartment GO Term

Extracellular vesicle 128 | 128
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Exosome component 10 EXOSC10 Tbio Non-IDG -2.45249 279.1 123
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Alpha-N-acetylglucosaminidase NAGLU Tbio Enzyme -2.18649 159.9 64
Sorting nexin-18 SNX18 Tbio Non-IDG -0.76724 7.20 156
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.20358 1618.6 2244
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332