Development Level

Tbio 838 | 11,445
Tchem 160 | 1,598
Tdark 66 | 6,588
Tclin 60 | 613

Collection

GPCR: IDG Consortium (Complete... 2 | 25
Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 40 | 979
enlarged heart 30 | 210
preweaning lethality, incomple... 27 | 499
decreased vertical activity 24 | 208
abnormal heart morphology 20 | 162
embryonic lethality prior to t... 17 | 278
abnormal embryo size 14 | 220
abnormal seminal vesicle morph... 13 | 114
decreased total body fat amoun... 11 | 207
decreased circulating glucose ... 10 | 126
decreased lean body mass 10 | 135
short tibia 10 | 97
decreased body weight 9 | 161
embryonic lethality prior to o... 9 | 239
increased total body fat amoun... 9 | 134
abnormal bone structure 8 | 187
cataract 8 | 92
hypoactivity 8 | 132
increased circulating alkaline... 8 | 122
increased mean corpuscular vol... 8 | 92
small superior vagus ganglion 8 | 74
abnormal kidney morphology 7 | 65
decreased bone mineral content 7 | 151
decreased mean corpuscular vol... 7 | 79
impaired glucose tolerance 7 | 75
increased bone mineral content 7 | 108
increased leukocyte cell numbe... 7 | 47
increased lymphocyte cell numb... 7 | 32
increased mean corpuscular hem... 7 | 96
abnormal behavior 6 | 298
abnormal eye morphology 6 | 68
abnormal gait 6 | 69
abnormal sleep behavior 6 | 70
decreased circulating choleste... 6 | 93
decreased circulating insulin ... 6 | 76
decreased fasted circulating g... 6 | 65
hyperactivity 6 | 148
increased bone mineral density 6 | 72
increased circulating choleste... 6 | 66
increased fasted circulating g... 6 | 76
increased startle reflex 6 | 112
limb grasping 6 | 41
prolonged ST segment 6 | 36
abnormal lens morphology 5 | 81
cardiovascular system phenotyp... 5 | 36
decreased blood urea nitrogen ... 5 | 51
decreased circulating HDL chol... 5 | 68
decreased circulating creatini... 5 | 39
decreased circulating serum al... 5 | 82
decreased circulating triglyce... 5 | 79
decreased erythrocyte cell num... 5 | 62
decreased grip strength 5 | 116
decreased startle reflex 5 | 75
embryonic growth retardation 5 | 106
improved glucose tolerance 5 | 79
increased circulating HDL chol... 5 | 80
increased heart weight 5 | 62
increased hematocrit 5 | 46
increased lean body mass 5 | 172
increased monocyte cell number 5 | 63
increased neutrophil cell numb... 5 | 46
prolonged QT interval 5 | 38
abnormal lung morphology 4 | 26
abnormal retina morphology 4 | 71
abnormal testis morphology 4 | 43
decreased bone mineral density 4 | 126
decreased circulating aspartat... 4 | 34
decreased circulating bilirubi... 4 | 19
decreased hematocrit 4 | 46
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular hem... 4 | 31
decreased neutrophil cell numb... 4 | 42
hydrometra 4 | 53
impaired righting response 4 | 26
increased circulating iron lev... 4 | 30
increased circulating triglyce... 4 | 42
increased mean corpuscular hem... 4 | 36
male infertility 4 | 123
abnormal coat- hair morphology 3 | 19
abnormal coat-hair pigmentatio... 3 | 64
abnormal cranium morphology 3 | 36
abnormal neural tube closure 3 | 46
abnormal retinal vasculature m... 3 | 27
abnormal tooth morphology 3 | 24
decreased body length 3 | 101
decreased circulating free fat... 3 | 31
decreased circulating iron lev... 3 | 32
decreased eosinophil cell numb... 3 | 24
decreased leukocyte cell numbe... 3 | 73
decreased prepulse inhibition 3 | 82
enlarged lymph nodes 3 | 37
enlarged spleen 3 | 41
increased blood urea nitrogen ... 3 | 48
increased circulating sodium l... 3 | 71
increased or absent threshold ... 3 | 101
pale yolk sac 3 | 25
persistence of hyaloid vascula... 3 | 33
small testis 3 | 58
corneal opacity 2 | 32
increased prepulse inhibition 2 | 32

Disease

Carcinoma 585 | 11,493
psoriasis 528 | 6,694
ovarian cancer 459 | 8,520
Cancer 426 | 2,499
osteosarcoma 395 | 7,950
lung cancer 387 | 4,740
glioblastoma 354 | 5,792
medulloblastoma, large-cell 306 | 6,241
lung carcinoma 301 | 2,843
non-small cell lung cancer 282 | 2,890
Breast cancer 281 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 280 | 2,955
lung adenocarcinoma 280 | 2,716
diabetes mellitus 274 | 1,728
pancreatic cancer 273 | 2,398
interstitial cystitis 271 | 2,312
invasive ductal carcinoma 271 | 2,951
malignant mesothelioma 269 | 3,232
ependymoma 263 | 4,679
Astrocytoma, Pilocytic 256 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 256 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 252 | 2,989
atypical teratoid / rhabdoid tumor 243 | 5,112
cystic fibrosis 236 | 1,696
adult high grade glioma 234 | 3,801
ulcerative colitis 233 | 1,819
tuberculosis 196 | 2,010
group 3 medulloblastoma 185 | 4,104
pituitary cancer 180 | 1,972
Autosomal recessive predisposition 178 | 1,442
ductal carcinoma in situ 173 | 1,745
breast carcinoma 171 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 171 | 1,962
Atherosclerosis 170 | 291
Kidney disease 157 | 430
Atopic dermatitis 148 | 952
Coronary artery disease 148 | 268
Obesity 147 | 678
oligodendroglioma 146 | 2,850
colon cancer 142 | 1,478
Liver Cirrhosis, Experimental 140 | 769
subependymal giant cell astrocytoma 140 | 2,287
Hypertension 136 | 396
Schizophrenia 136 | 1,160
cutaneous lupus erythematosus 136 | 1,057
Kidney cancer 131 | 2,613
primitive neuroectodermal tumor 130 | 3,035
adrenocortical carcinoma 129 | 1,428
astrocytic glioma 128 | 2,597
primary pancreatic ductal adenocarcinoma 127 | 1,109
Asthma 123 | 385
Rheumatoid arthritis 120 | 1,191
Arthritis 118 | 290
gastric carcinoma 114 | 807
nasopharyngeal carcinoma 107 | 1,058
Heart disease 102 | 306
Duchenne muscular dystrophy 101 | 601
Multiple Sclerosis 100 | 540
juvenile dermatomyositis 99 | 1,187
Cerebrovascular disease 96 | 238
esophageal adenocarcinoma 96 | 737
group 4 medulloblastoma 95 | 1,855
Liver disease 94 | 237
Lung disease 94 | 142
Vascular disease 94 | 319
active Crohn's disease 93 | 922
Prostatic Neoplasms 91 | 495
Hypersensitivity reaction type II disease 89 | 253
Alzheimer's disease 85 | 658
fibroadenoma 85 | 559
Anemia 83 | 365
Hypertensive disease 83 | 292
active ulcerative colitis 83 | 764
acute quadriplegic myopathy 82 | 1,158
astrocytoma 81 | 1,146
Inflammatory bowel disease 80 | 151
Breast Neoplasms 79 | 445
Bipolar Disorder 78 | 666
Endometriosis 78 | 540
Mammary Neoplasms 78 | 425
Osteoporosis 76 | 363
autosomal dominant Emery-Dreifuss muscular dystrophy 76 | 510
mucosa-associated lymphoid tissue lymphoma 76 | 484
pediatric high grade glioma 75 | 1,064
Pick disease 72 | 1,894
Melanoma 70 | 711
Depressive disorder 69 | 409
primary Sjogren syndrome 67 | 735
Lipid metabolism disorder 66 | 114
periodontitis 66 | 293
Liver Cirrhosis 65 | 181
Pneumonia 65 | 174
Inflammation 64 | 120
Diarrhea 62 | 253
Chemical and Drug Induced Liver Injury 60 | 195
dermatomyositis 60 | 966
sarcoidosis 60 | 370
spina bifida 60 | 1,074
Dermatitis 59 | 157
Down syndrome 58 | 499

Tissue

Endocrine System 1,064 | 18,159
Digestive Tract 1,059 | 17,369
Female tissues 1,045 | 17,400
Skin and soft tissues 1,032 | 17,230
Liver and Pancreas 1,016 | 16,750
Male tissues 1,010 | 17,142
Blood and immune system 1,009 | 16,909
Urinary Tract 997 | 16,678
Respiratory system 962 | 16,393
Nervous System 944 | 16,725
Cardiovascular System 813 | 15,192

Target Family

Non-IDG 836 | 12,091
Enzyme 241 | 4,145
Kinase 18 | 634
Transcription Factor 16 | 1,400
Transporter 4 | 473
GPCR 3 | 408
Ion Channel 3 | 344
Nuclear Receptor 2 | 48
Epigenetic 1 | 242

Compartment GO Term

Extracellular space 1,124 | 1,124
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314
Serpin B12 SERPINB12 Tbio Non-IDG -0.56624 4.27 155
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Hypoxia-inducible lipid droplet-associated protein HILPDA Tbio Non-IDG -1.24205 21.6 18
Sperm acrosome-associated protein 5 SPACA5B Tdark Enzyme 0.14 0.79 56
Fibrocystin-L PKHD1L1 Tdark Non-IDG -0.48112 3.05 17
Extracellular matrix protein 2 ECM2 Tdark Non-IDG -0.89859 7.20 22
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Vigilin HDLBP Tbio Non-IDG -2.01228 106.9 233