Development Level

Tbio 909 | 10,625
Tchem 249 | 1,890
Tdark 105 | 7,003
Tclin 66 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 26
GPCR: IDG Consortium (Targets) 1 | 127
Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 41 | 633
enlarged heart 24 | 111
preweaning lethality, incomple... 18 | 260
decreased lean body mass 15 | 195
embryonic lethality prior to t... 15 | 187
decreased total body fat amoun... 13 | 186
abnormal embryo size 12 | 112
decreased body weight 12 | 174
abnormal heart morphology 11 | 51
decreased bone mineral content 11 | 157
decreased circulating insulin ... 10 | 75
abnormal seminal vesicle morph... 9 | 47
decreased grip strength 9 | 123
increased circulating alkaline... 9 | 119
decreased bone mineral density 8 | 126
embryonic lethality prior to o... 8 | 148
short tibia 8 | 82
abnormal behavior 7 | 226
abnormal lens morphology 7 | 73
abnormal retina morphology 7 | 100
impaired glucose tolerance 7 | 52
increased mean corpuscular vol... 7 | 91
abnormal bone structure 6 | 131
decreased body length 6 | 108
decreased circulating glucose ... 6 | 121
enlarged epididymis 6 | 27
hypoactivity 6 | 89
increased hematocrit 6 | 36
increased total body fat amoun... 6 | 57
abnormal epididymis morphology 5 | 31
abnormal sleep behavior 5 | 63
decreased circulating free fat... 5 | 39
decreased circulating triglyce... 5 | 83
improved glucose tolerance 5 | 56
increased bone mineral content 5 | 92
increased bone mineral density 5 | 52
increased circulating HDL chol... 5 | 63
increased circulating choleste... 5 | 53
increased circulating sodium l... 5 | 71
increased exploration in new e... 5 | 56
increased leukocyte cell numbe... 5 | 37
increased or absent threshold ... 5 | 128
limb grasping 5 | 35
abnormal coat-hair pigmentatio... 4 | 54
abnormal coping response 4 | 12
abnormal kidney morphology 4 | 30
abnormal neural tube closure 4 | 37
abnormal skin morphology 4 | 23
cataract 4 | 26
decreased circulating HDL chol... 4 | 77
decreased circulating alanine ... 4 | 53
decreased circulating choleste... 4 | 85
decreased heart weight 4 | 44
decreased monocyte cell number 4 | 28
decreased prepulse inhibition 4 | 52
decreased startle reflex 4 | 48
decreased threshold for audito... 4 | 32
increased circulating triglyce... 4 | 24
increased fasted circulating g... 4 | 68
increased grip strength 4 | 83
increased hemoglobin content 4 | 45
increased lean body mass 4 | 107
increased mean corpuscular hem... 4 | 93
increased startle reflex 4 | 38
male infertility 4 | 62
small testis 4 | 37
abnormal behavioral response t... 3 | 52
abnormal bone mineralization 3 | 55
abnormal coat appearance 3 | 25
abnormal eye morphology 3 | 38
abnormal lung morphology 3 | 15
abnormal neural tube morpholog... 3 | 8
abnormal testis morphology 3 | 30
abnormal tooth morphology 3 | 24
cardiovascular system phenotyp... 3 | 35
decreased B cell number 3 | 30
decreased T cell number 3 | 31
decreased caudal vertebrae num... 3 | 49
decreased circulating aspartat... 3 | 27
decreased circulating bilirubi... 3 | 14
decreased circulating calcium ... 3 | 33
decreased circulating chloride... 3 | 32
decreased circulating creatini... 3 | 31
decreased circulating iron lev... 3 | 25
decreased circulating serum al... 3 | 79
decreased eosinophil cell numb... 3 | 41
decreased fasted circulating g... 3 | 49
decreased lumbar vertebrae num... 3 | 62
decreased mean corpuscular hem... 3 | 19
decreased mean corpuscular vol... 3 | 50
decreased rib number 3 | 59
embryonic growth retardation 3 | 28
enlarged lymph nodes 3 | 27
enlarged spleen 3 | 26
female infertility 3 | 34
hydrops fetalis 3 | 22
immune system phenotype 3 | 17
increased lymphocyte cell numb... 3 | 9
increased NK T cell number 2 | 11
increased body weight 2 | 42

Disease

psoriasis 617 | 6,685
ovarian cancer 581 | 8,491
osteosarcoma 479 | 7,933
Cancer 459 | 2,346
lung cancer 439 | 4,473
glioblastoma 407 | 5,572
medulloblastoma, large-cell 372 | 6,234
lung carcinoma 344 | 2,844
lung adenocarcinoma 326 | 2,714
intraductal papillary-mucinous adenoma (IPMA) 321 | 2,956
invasive ductal carcinoma 315 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 308 | 3,289
pancreatic cancer 307 | 2,300
ulcerative colitis 306 | 2,087
non-small cell lung cancer 301 | 2,798
pilocytic astrocytoma 301 | 3,086
interstitial cystitis 298 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 298 | 2,988
malignant mesothelioma 295 | 3,163
diabetes mellitus 290 | 1,663
Breast cancer 287 | 3,098
cystic fibrosis 268 | 1,670
atypical teratoid / rhabdoid tumor 256 | 4,369
pediatric high grade glioma 211 | 2,712
breast carcinoma 201 | 1,614
pituitary cancer 197 | 1,972
tuberculosis 195 | 1,563
ductal carcinoma in situ 194 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 194 | 1,795
subependymal giant cell astrocytoma 179 | 2,287
posterior fossa group A ependymoma 175 | 1,511
primary pancreatic ductal adenocarcinoma 175 | 1,271
colon cancer 174 | 1,475
oligodendroglioma 171 | 2,849
Atopic dermatitis 165 | 944
Atherosclerosis 161 | 275
primitive neuroectodermal tumor 160 | 3,031
adult high grade glioma 158 | 2,148
Kidney disease 153 | 397
cutaneous lupus erythematosus 151 | 1,056
Obesity 146 | 616
adrenocortical carcinoma 142 | 1,427
Coronary artery disease 140 | 240
Carcinoma 139 | 2,147
Rheumatoid Arthritis 136 | 1,170
gastric carcinoma 131 | 832
ependymoma 130 | 2,514
sonic hedgehog group medulloblastoma 128 | 1,482
juvenile dermatomyositis 125 | 1,189
astrocytic glioma 124 | 2,241
nasopharyngeal carcinoma 124 | 1,056
Asthma 123 | 349
Duchenne muscular dystrophy 122 | 602
group 4 medulloblastoma 121 | 1,875
astrocytoma 120 | 1,493
esophageal adenocarcinoma 118 | 737
group 3 medulloblastoma 117 | 2,254
Hypertension 111 | 293
acute quadriplegic myopathy 111 | 1,157
Arthritis 108 | 248
Heart disease 106 | 279
active Crohn's disease 106 | 918
Prostatic Neoplasms 102 | 471
Pick disease 100 | 1,893
Alzheimer's disease 96 | 644
Cerebrovascular disease 95 | 231
Multiple Sclerosis 95 | 498
fibroadenoma 95 | 557
Vascular disease 94 | 281
Mammary Neoplasms 92 | 410
Lung disease 91 | 136
mucosa-associated lymphoid tissue lymphoma 91 | 480
primary Sjogren syndrome 91 | 788
Endometriosis 90 | 535
Liver disease 89 | 219
autosomal dominant Emery-Dreifuss muscular dystrophy 87 | 499
posterior fossa group B ependymoma 86 | 1,530
Hypersensitivity reaction type II disease 84 | 235
dermatomyositis 80 | 966
Anemia 78 | 252
spina bifida 77 | 1,064
Down syndrome 75 | 548
Inflammatory bowel disease 73 | 142
Multiple myeloma 73 | 1,327
non-small cell lung carcinoma 72 | 413
Osteoporosis 70 | 259
Hypertensive disease 66 | 193
aldosterone-producing adenoma 66 | 664
atypical teratoid/rhabdoid tumor 66 | 1,095
periodontitis 66 | 269
Metabolic syndrome X 65 | 155
Pneumonia 64 | 133
Stomach Neoplasms 64 | 282
medulloblastoma 61 | 1,524
Inflammation 60 | 109
Lipid metabolism disorder 60 | 102
Becker muscular dystrophy 59 | 187
IGA Glomerulonephritis 58 | 454
head and neck cancer and chronic obstructive pulmonary disease 58 | 237
limb girdle muscular dystrophy 2A 58 | 156

Tissue

Digestive Tract 1,289 | 18,472
Nervous System 1,286 | 18,560
Female tissues 1,284 | 18,646
Endocrine System 1,278 | 18,511
Urinary Tract 1,274 | 18,443
Skin and soft tissues 1,269 | 18,114
Liver and Pancreas 1,255 | 18,135
Blood and immune system 1,247 | 17,994
Cardiovascular System 1,243 | 17,957
Male tissues 1,232 | 17,968
Respiratory system 1,222 | 17,483

Target Family

Non-IDG 980 | 11,969
Enzyme 288 | 4,146
Kinase 23 | 634
Transcription Factor 17 | 1,400
Transporter 8 | 473
Epigenetic 4 | 242
GPCR 4 | 408
Ion Channel 3 | 341
Nuclear Receptor 2 | 48

Compartment GO Term

Extracellular space 1,329 | 1,329
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.46520 301.6 339
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Angiopoietin-related protein 2 ANGPTL2 Tbio Non-IDG -1.74019 67.9 132
Interferon gamma receptor 1 IFNGR1 Tchem Non-IDG -2.19638 160.9 450
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
Galectin-3 LGALS3 Tchem Non-IDG -3.33005 2249.5 911
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.34747 2121.3 411
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.36387 2061.0 806
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.24582 1740.5 143