Development Level

Tbio 909 | 10,625
Tchem 249 | 1,890
Tdark 105 | 7,003
Tclin 66 | 602

Collection

Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 41 | 633
enlarged heart 24 | 111
preweaning lethality, incomple... 18 | 260
decreased lean body mass 15 | 195
embryonic lethality prior to t... 15 | 187
decreased total body fat amoun... 13 | 186
abnormal embryo size 12 | 112
decreased body weight 12 | 174
abnormal heart morphology 11 | 51
decreased bone mineral content 11 | 157
decreased circulating insulin ... 10 | 75
abnormal seminal vesicle morph... 9 | 47
decreased grip strength 9 | 123
increased circulating alkaline... 9 | 119
decreased bone mineral density 8 | 126
embryonic lethality prior to o... 8 | 148
short tibia 8 | 82
abnormal behavior 7 | 226
abnormal lens morphology 7 | 73
abnormal retina morphology 7 | 100
impaired glucose tolerance 7 | 52
increased mean corpuscular vol... 7 | 91
abnormal bone structure 6 | 131
decreased body length 6 | 108
decreased circulating glucose ... 6 | 121
enlarged epididymis 6 | 27
hypoactivity 6 | 89
increased hematocrit 6 | 36
increased total body fat amoun... 6 | 57
abnormal epididymis morphology 5 | 31
abnormal sleep behavior 5 | 63
decreased circulating free fat... 5 | 39
decreased circulating triglyce... 5 | 83
improved glucose tolerance 5 | 56
increased bone mineral content 5 | 92
increased bone mineral density 5 | 52
increased circulating HDL chol... 5 | 63
increased circulating choleste... 5 | 53
increased circulating sodium l... 5 | 71
increased exploration in new e... 5 | 56
increased leukocyte cell numbe... 5 | 37
increased or absent threshold ... 5 | 128
limb grasping 5 | 35
abnormal coat/hair pigmentatio... 4 | 54
abnormal coping response 4 | 12
abnormal kidney morphology 4 | 30
abnormal neural tube closure 4 | 37
abnormal skin morphology 4 | 23
cataract 4 | 26
decreased circulating HDL chol... 4 | 77
decreased circulating alanine ... 4 | 53
decreased circulating choleste... 4 | 85
decreased heart weight 4 | 44
decreased monocyte cell number 4 | 28
decreased prepulse inhibition 4 | 52
decreased startle reflex 4 | 48
decreased threshold for audito... 4 | 32
increased circulating triglyce... 4 | 24
increased fasted circulating g... 4 | 68
increased grip strength 4 | 83
increased hemoglobin content 4 | 45
increased lean body mass 4 | 107
increased mean corpuscular hem... 4 | 93
increased startle reflex 4 | 38
male infertility 4 | 62
small testis 4 | 37
abnormal behavioral response t... 3 | 52
abnormal bone mineralization 3 | 55
abnormal coat appearance 3 | 25
abnormal eye morphology 3 | 38
abnormal lung morphology 3 | 15
abnormal neural tube morpholog... 3 | 8
abnormal testis morphology 3 | 30
abnormal tooth morphology 3 | 24
cardiovascular system phenotyp... 3 | 35
decreased B cell number 3 | 30
decreased T cell number 3 | 31
decreased caudal vertebrae num... 3 | 49
decreased circulating aspartat... 3 | 27
decreased circulating bilirubi... 3 | 14
decreased circulating calcium ... 3 | 33
decreased circulating chloride... 3 | 32
decreased circulating creatini... 3 | 31
decreased circulating iron lev... 3 | 25
decreased circulating serum al... 3 | 79
decreased eosinophil cell numb... 3 | 41
decreased fasted circulating g... 3 | 49
decreased lumbar vertebrae num... 3 | 62
decreased mean corpuscular hem... 3 | 19
decreased mean corpuscular vol... 3 | 50
decreased rib number 3 | 59
embryonic growth retardation 3 | 28
enlarged lymph nodes 3 | 27
enlarged spleen 3 | 26
female infertility 3 | 34
hydrops fetalis 3 | 22
immune system phenotype 3 | 17
increased lymphocyte cell numb... 3 | 9
increased NK T cell number 2 | 11
increased body weight 2 | 42

Disease

psoriasis 617 | 6,685
ovarian cancer 581 | 8,484
osteosarcoma 479 | 7,933
Cancer 459 | 2,346
lung cancer 438 | 4,466
glioblastoma 407 | 5,572
medulloblastoma, large-cell 372 | 6,234
lung carcinoma 344 | 2,844
lung adenocarcinoma 326 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 321 | 2,956
invasive ductal carcinoma 315 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 308 | 3,289
pancreatic cancer 307 | 2,300
ulcerative colitis 306 | 2,087
non-small cell lung cancer 301 | 2,798
pilocytic astrocytoma 301 | 3,086
interstitial cystitis 298 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 298 | 2,988
malignant mesothelioma 295 | 3,162
diabetes mellitus 290 | 1,663
Breast cancer 285 | 3,094
cystic fibrosis 266 | 1,665
atypical teratoid / rhabdoid tumor 256 | 4,369
pediatric high grade glioma 211 | 2,712
breast carcinoma 201 | 1,614
pituitary cancer 197 | 1,972
tuberculosis 195 | 1,557
ductal carcinoma in situ 194 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 194 | 1,795
subependymal giant cell astrocytoma 179 | 2,287
posterior fossa group A ependymoma 175 | 1,511
primary pancreatic ductal adenocarcinoma 175 | 1,271
colon cancer 174 | 1,475
oligodendroglioma 171 | 2,849
Atopic dermatitis 165 | 944
Atherosclerosis 161 | 275
primitive neuroectodermal tumor 160 | 3,031
adult high grade glioma 158 | 2,148
Kidney disease 153 | 396
cutaneous lupus erythematosus 151 | 1,056
Obesity 146 | 616
adrenocortical carcinoma 142 | 1,427
Coronary artery disease 140 | 240
Carcinoma 139 | 2,147
Rheumatoid Arthritis 136 | 1,160
gastric carcinoma 131 | 832
ependymoma 130 | 2,514
sonic hedgehog group medulloblastoma 128 | 1,482
juvenile dermatomyositis 125 | 1,189
astrocytic glioma 124 | 2,241
nasopharyngeal carcinoma 124 | 1,056
Asthma 123 | 349
Duchenne muscular dystrophy 122 | 602
group 4 medulloblastoma 121 | 1,875
astrocytoma 120 | 1,493
esophageal adenocarcinoma 118 | 737
group 3 medulloblastoma 117 | 2,254
acute quadriplegic myopathy 111 | 1,157
Hypertension 110 | 287
Arthritis 108 | 248
Heart disease 106 | 279
active Crohn's disease 106 | 918
Prostatic Neoplasms 102 | 471
Pick disease 100 | 1,893
Alzheimer's disease 96 | 644
Cerebrovascular disease 95 | 231
Multiple Sclerosis 95 | 498
fibroadenoma 95 | 557
Vascular disease 94 | 281
Mammary Neoplasms 92 | 410
mucosa-associated lymphoid tissue lymphoma 91 | 480
primary Sjogren syndrome 91 | 789
Endometriosis 90 | 535
Liver disease 89 | 219
Lung disease 89 | 132
autosomal dominant Emery-Dreifuss muscular dystrophy 87 | 499
posterior fossa group B ependymoma 86 | 1,530
Hypersensitivity reaction type II disease 84 | 235
dermatomyositis 80 | 933
Anemia 78 | 252
spina bifida 77 | 1,064
Down syndrome 75 | 548
Inflammatory bowel disease 73 | 142
Multiple myeloma 73 | 1,327
non-small cell lung carcinoma 72 | 413
Osteoporosis 70 | 257
Hypertensive disease 66 | 193
aldosterone-producing adenoma 66 | 664
atypical teratoid/rhabdoid tumor 66 | 1,095
periodontitis 66 | 269
Metabolic syndrome X 65 | 155
Pneumonia 64 | 133
Stomach Neoplasms 64 | 282
medulloblastoma 61 | 1,524
Inflammation 60 | 109
Lipid metabolism disorder 60 | 102
Becker muscular dystrophy 59 | 187
IGA Glomerulonephritis 58 | 454
head and neck cancer and chronic obstructive pulmonary disease 58 | 237
limb girdle muscular dystrophy 2A 58 | 156

Tissue

Digestive Tract 1,289 | 18,473
Nervous System 1,286 | 18,561
Female tissues 1,284 | 18,647
Endocrine System 1,278 | 18,512
Urinary Tract 1,274 | 18,444
Skin and soft tissues 1,269 | 18,115
Liver and Pancreas 1,255 | 18,136
Blood and immune system 1,247 | 17,995
Cardiovascular System 1,243 | 17,958
Male tissues 1,232 | 17,969
Respiratory system 1,222 | 17,484

Target Family

Non-IDG 980 | 11,971
Enzyme 288 | 4,146
Kinase 23 | 634
Transcription Factor 17 | 1,400
Transporter 8 | 473
Epigenetic 4 | 242
GPCR 4 | 406
Ion Channel 3 | 341
Nuclear Receptor 2 | 48

Compartment GO Term

Extracellular space 1,329 | 1,329
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.34520 2413.2 212
Antileukoproteinase SLPI Tbio Enzyme -2.56514 434.2 290
Transmembrane protease serine 6 TMPRSS6 Tchem Enzyme -1.99222 118.1 102