Development Level

Tbio 1,202 | 11,445
Tchem 234 | 1,598
Tdark 99 | 6,588
Tclin 92 | 613

Collection

Ion Channel: IDG Consortium (T... 3 | 99
GPCR: IDG Consortium (Complete... 2 | 25
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 68 | 979
preweaning lethality, incomple... 44 | 499
enlarged heart 35 | 210
embryonic lethality prior to t... 31 | 278
decreased vertical activity 27 | 208
abnormal heart morphology 24 | 162
abnormal embryo size 20 | 220
abnormal seminal vesicle morph... 19 | 114
embryonic lethality prior to o... 19 | 239
decreased total body fat amoun... 17 | 207
increased circulating alkaline... 16 | 122
short tibia 16 | 97
cataract 14 | 92
decreased body weight 14 | 161
increased total body fat amoun... 14 | 134
abnormal behavior 13 | 298
abnormal bone structure 13 | 187
decreased bone mineral content 13 | 151
decreased lean body mass 12 | 135
decreased body length 11 | 101
decreased mean corpuscular vol... 11 | 79
hypoactivity 11 | 132
small superior vagus ganglion 11 | 74
abnormal kidney morphology 10 | 65
abnormal lens morphology 10 | 81
decreased circulating glucose ... 10 | 126
decreased circulating insulin ... 10 | 76
hyperactivity 10 | 148
improved glucose tolerance 10 | 79
increased mean corpuscular vol... 10 | 92
increased neutrophil cell numb... 10 | 46
decreased circulating serum al... 9 | 82
decreased grip strength 9 | 116
embryonic growth retardation 9 | 106
impaired glucose tolerance 9 | 75
increased bone mineral content 9 | 108
increased bone mineral density 9 | 72
increased circulating HDL chol... 9 | 80
increased circulating choleste... 9 | 66
increased leukocyte cell numbe... 9 | 47
increased startle reflex 9 | 112
abnormal eye morphology 8 | 68
abnormal retina morphology 8 | 71
decreased circulating triglyce... 8 | 79
decreased erythrocyte cell num... 8 | 62
decreased lymphocyte cell numb... 8 | 83
decreased neutrophil cell numb... 8 | 42
increased heart weight 8 | 62
increased lymphocyte cell numb... 8 | 32
increased mean corpuscular hem... 8 | 96
abnormal coat-hair pigmentatio... 7 | 64
abnormal gait 7 | 69
abnormal skin morphology 7 | 50
abnormal sleep behavior 7 | 70
decreased blood urea nitrogen ... 7 | 51
decreased circulating choleste... 7 | 93
decreased startle reflex 7 | 75
increased circulating triglyce... 7 | 42
increased fasted circulating g... 7 | 76
increased lean body mass 7 | 172
increased or absent threshold ... 7 | 101
male infertility 7 | 123
prolonged ST segment 7 | 36
abnormal cranium morphology 6 | 36
cardiovascular system phenotyp... 6 | 36
decreased circulating creatini... 6 | 39
decreased fasted circulating g... 6 | 65
hydrometra 6 | 53
impaired righting response 6 | 26
increased blood urea nitrogen ... 6 | 48
increased monocyte cell number 6 | 63
limb grasping 6 | 41
persistence of hyaloid vascula... 6 | 33
abnormal femur morphology 5 | 14
abnormal lung morphology 5 | 26
abnormal testis morphology 5 | 43
abnormal tooth morphology 5 | 24
decreased bone mineral density 5 | 126
decreased circulating HDL chol... 5 | 68
decreased circulating aspartat... 5 | 34
decreased circulating bilirubi... 5 | 19
decreased circulating total pr... 5 | 49
decreased hematocrit 5 | 46
decreased hemoglobin content 5 | 68
decreased mean corpuscular hem... 5 | 31
decreased prepulse inhibition 5 | 82
enlarged spleen 5 | 41
increased circulating amylase ... 5 | 25
increased circulating creatini... 5 | 38
increased hematocrit 5 | 46
prenatal lethality prior to he... 5 | 87
prolonged QT interval 5 | 38
small testis 5 | 58
abnormal bone mineralization 4 | 38
abnormal liver morphology 4 | 17
abnormal retinal vasculature m... 4 | 27
abnormal vibrissa morphology 4 | 25
decreased circulating free fat... 4 | 31
decreased circulating iron lev... 4 | 32
decreased spleen weight 4 | 10

Disease

Carcinoma 967 | 11,493
psoriasis 760 | 6,694
ovarian cancer 744 | 8,520
Cancer 652 | 2,499
osteosarcoma 618 | 7,950
glioblastoma 584 | 5,792
lung cancer 580 | 4,740
medulloblastoma, large-cell 484 | 6,241
Breast cancer 470 | 3,578
lung carcinoma 446 | 2,843
ependymoma 433 | 4,679
non-small cell lung cancer 431 | 2,890
invasive ductal carcinoma 429 | 2,951
malignant mesothelioma 429 | 3,232
lung adenocarcinoma 423 | 2,716
pancreatic cancer 412 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 406 | 2,955
atypical teratoid / rhabdoid tumor 405 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 400 | 3,291
Astrocytoma, Pilocytic 396 | 3,081
interstitial cystitis 396 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 379 | 2,989
adult high grade glioma 370 | 3,801
diabetes mellitus 361 | 1,728
cystic fibrosis 333 | 1,696
ulcerative colitis 329 | 1,819
group 3 medulloblastoma 301 | 4,104
breast carcinoma 278 | 1,638
ductal carcinoma in situ 275 | 1,745
Autosomal recessive predisposition 271 | 1,442
pituitary cancer 271 | 1,972
Kidney cancer 260 | 2,613
tuberculosis 259 | 2,010
oligodendroglioma 254 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 237 | 1,962
Kidney disease 226 | 430
subependymal giant cell astrocytoma 226 | 2,287
primitive neuroectodermal tumor 223 | 3,035
colon cancer 216 | 1,478
astrocytic glioma 215 | 2,597
Schizophrenia 204 | 1,160
primary pancreatic ductal adenocarcinoma 204 | 1,109
Atopic dermatitis 198 | 952
adrenocortical carcinoma 197 | 1,428
cutaneous lupus erythematosus 197 | 1,057
Liver Cirrhosis, Experimental 196 | 769
Atherosclerosis 195 | 291
Hypertension 186 | 396
Obesity 182 | 678
Coronary artery disease 168 | 268
gastric carcinoma 168 | 807
Rheumatoid arthritis 167 | 1,191
Duchenne muscular dystrophy 162 | 601
juvenile dermatomyositis 162 | 1,187
nasopharyngeal carcinoma 162 | 1,058
group 4 medulloblastoma 157 | 1,855
Arthritis 156 | 290
Asthma 152 | 385
Vascular disease 144 | 319
esophageal adenocarcinoma 136 | 737
Breast Neoplasms 134 | 445
Heart disease 132 | 306
Prostatic Neoplasms 132 | 495
Mammary Neoplasms 131 | 425
Melanoma 130 | 711
autosomal dominant Emery-Dreifuss muscular dystrophy 130 | 510
Multiple Sclerosis 129 | 540
acute quadriplegic myopathy 126 | 1,158
Alzheimer's disease 124 | 658
Cerebrovascular disease 124 | 238
astrocytoma 124 | 1,146
Pick disease 123 | 1,894
active Crohn's disease 122 | 922
active ulcerative colitis 122 | 764
Hypertensive disease 121 | 292
fibroadenoma 119 | 559
Endometriosis 118 | 540
Lung disease 118 | 142
pediatric high grade glioma 118 | 1,064
Liver disease 117 | 237
Hypersensitivity reaction type II disease 115 | 253
Anemia 113 | 365
Osteoporosis 109 | 363
Bipolar Disorder 105 | 666
dermatomyositis 105 | 966
mucosa-associated lymphoid tissue lymphoma 101 | 484
Depressive disorder 97 | 409
primary Sjogren syndrome 97 | 735
Inflammatory bowel disease 96 | 151
Liver cancer 92 | 604
Short stature 92 | 531
Skin cancer 92 | 469
Down syndrome 90 | 499
Epilepsy 90 | 792
Multiple myeloma 89 | 1,332
Diarrhea 88 | 253
Intellectual disability 88 | 1,016
non primary Sjogren syndrome sicca 87 | 891
spina bifida 87 | 1,074
Lung Neoplasms 86 | 232

Tissue

Endocrine System 1,550 | 18,159
Digestive Tract 1,529 | 17,369
Female tissues 1,518 | 17,400
Skin and soft tissues 1,497 | 17,230
Male tissues 1,482 | 17,142
Liver and Pancreas 1,474 | 16,750
Blood and immune system 1,471 | 16,909
Urinary Tract 1,456 | 16,678
Nervous System 1,409 | 16,725
Respiratory system 1,408 | 16,393
Cardiovascular System 1,236 | 15,192

Target Family

Non-IDG 1,149 | 12,091
Enzyme 342 | 4,145
Kinase 50 | 634
Transcription Factor 47 | 1,400
Ion Channel 10 | 344
Transporter 10 | 473
GPCR 9 | 408
Nuclear Receptor 8 | 48
Epigenetic 2 | 242

Compartment GO Term

Extracellular region part 1,627 | 1,627
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Kallikrein-12 KLK12 Tbio Enzyme -0.99694 11.0 111
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
Neuroendocrine convertase 2 PCSK2 Tchem Enzyme -2.00248 109.8 132
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Spondin-2 SPON2 Tbio Non-IDG -1.73555 56.2 210
Interleukin-18-binding protein IL18BP Tbio Non-IDG -2.00596 101.6 307
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93