Development Level

Tbio 2,999 | 10,625
Tchem 712 | 1,890
Tdark 682 | 7,003
Tclin 213 | 602

Collection

Eligible Ion Channel Proteins 14 | 117
Eligible Kinase Proteins 9 | 134
Eligible non-olfactory GPCR Proteins 7 | 143

IMPC Term

preweaning lethality, complete... 158 | 633
preweaning lethality, incomple... 67 | 260
decreased lean body mass 64 | 195
abnormal behavior 60 | 226
embryonic lethality prior to t... 57 | 187
decreased total body fat amoun... 56 | 186
decreased bone mineral content 50 | 157
enlarged heart 44 | 111
embryonic lethality prior to o... 42 | 148
decreased body weight 40 | 174
decreased grip strength 38 | 123
increased circulating alkaline... 38 | 119
abnormal bone structure 37 | 131
increased or absent threshold ... 37 | 128
abnormal embryo size 33 | 112
decreased bone mineral density 33 | 126
decreased body length 31 | 108
short tibia 30 | 82
hypoactivity 29 | 89
increased lean body mass 28 | 107
abnormal retina morphology 27 | 100
decreased circulating insulin ... 27 | 75
hyperactivity 27 | 108
increased mean corpuscular vol... 27 | 91
abnormal lens morphology 26 | 73
increased mean corpuscular hem... 26 | 93
decreased circulating glucose ... 25 | 121
decreased circulating triglyce... 22 | 83
abnormal heart morphology 21 | 51
improved glucose tolerance 21 | 56
abnormal seminal vesicle morph... 20 | 47
decreased mean corpuscular vol... 20 | 50
impaired glucose tolerance 20 | 52
increased bone mineral content 20 | 92
decreased circulating HDL chol... 19 | 77
decreased circulating serum al... 19 | 79
increased exploration in new e... 19 | 56
increased fasted circulating g... 19 | 68
increased grip strength 19 | 83
decreased heart weight 17 | 44
abnormal bone mineralization 16 | 55
abnormal retinal pigmentation 16 | 61
decreased circulating choleste... 16 | 85
decreased hemoglobin content 16 | 53
increased circulating HDL chol... 16 | 63
male infertility 16 | 62
decreased circulating alanine ... 15 | 53
decreased erythrocyte cell num... 15 | 43
decreased leukocyte cell numbe... 15 | 54
increased blood urea nitrogen ... 15 | 44
abnormal QRS complex 14 | 25
abnormal coat/hair pigmentatio... 14 | 54
abnormal cranium morphology 14 | 32
abnormal kidney morphology 14 | 30
abnormal neural tube closure 14 | 37
decreased startle reflex 14 | 48
increased circulating sodium l... 14 | 71
increased total body fat amoun... 14 | 57
abnormal sleep behavior 13 | 63
decreased prepulse inhibition 13 | 52
decreased rib number 13 | 59
decreased threshold for audito... 13 | 32
enlarged epididymis 13 | 27
increased hematocrit 13 | 36
prenatal lethality prior to he... 13 | 64
abnormal gait 12 | 51
decreased circulating alkaline... 12 | 41
decreased circulating free fat... 12 | 39
decreased mean corpuscular hem... 12 | 34
increased bone mineral density 12 | 52
increased circulating choleste... 12 | 53
increased hemoglobin content 12 | 45
small testis 12 | 37
thrombocytopenia 12 | 46
decreased eosinophil cell numb... 11 | 41
decreased fasted circulating g... 11 | 49
decreased lumbar vertebrae num... 11 | 62
increased body weight 11 | 42
increased heart weight 11 | 37
increased leukocyte cell numbe... 11 | 37
increased sacral vertebrae num... 11 | 62
abnormal behavioral response t... 10 | 52
abnormal coat appearance 10 | 25
abnormal epididymis morphology 10 | 31
abnormal tooth morphology 10 | 24
decreased caudal vertebrae num... 10 | 49
decreased circulating total pr... 10 | 41
immune system phenotype 10 | 17
increased circulating chloride... 10 | 43
abnormal eye morphology 9 | 38
abnormal skin morphology 9 | 23
abnormal testis morphology 9 | 30
abnormal vibrissa morphology 9 | 17
cardiovascular system phenotyp... 9 | 35
cataract 9 | 26
corneal opacity 9 | 25
increased circulating potassiu... 9 | 31
increased circulating total pr... 9 | 20
limb grasping 9 | 35
decreased circulating LDL chol... 8 | 37

Disease

ovarian cancer 2,214 | 8,484
psoriasis 1,963 | 6,685
osteosarcoma 1,806 | 7,933
glioblastoma 1,471 | 5,572
medulloblastoma, large-cell 1,457 | 6,234
lung cancer 1,400 | 4,466
Cancer 1,135 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 1,026 | 3,289
atypical teratoid / rhabdoid tumor 1,022 | 4,369
invasive ductal carcinoma 958 | 2,950
lung adenocarcinoma 942 | 2,713
lung carcinoma 941 | 2,844
pilocytic astrocytoma 941 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 938 | 2,956
malignant mesothelioma 936 | 3,162
Breast cancer 933 | 3,094
non-small cell lung cancer 930 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 925 | 2,988
pancreatic cancer 908 | 2,300
interstitial cystitis 811 | 2,299
ulcerative colitis 760 | 2,087
pediatric high grade glioma 733 | 2,712
oligodendroglioma 717 | 2,849
diabetes mellitus 714 | 1,663
primitive neuroectodermal tumor 679 | 3,031
cystic fibrosis 665 | 1,665
subependymal giant cell astrocytoma 637 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 597 | 1,795
ependymoma 596 | 2,514
ductal carcinoma in situ 589 | 1,745
breast carcinoma 588 | 1,614
pituitary cancer 575 | 1,972
Carcinoma 563 | 2,147
tuberculosis 536 | 1,557
adult high grade glioma 524 | 2,148
astrocytic glioma 514 | 2,241
primary pancreatic ductal adenocarcinoma 512 | 1,271
colon cancer 502 | 1,475
Multiple myeloma 484 | 1,327
posterior fossa group A ependymoma 483 | 1,511
astrocytoma 468 | 1,493
group 3 medulloblastoma 463 | 2,254
Pick disease 455 | 1,893
group 4 medulloblastoma 451 | 1,875
adrenocortical carcinoma 415 | 1,427
cutaneous lupus erythematosus 407 | 1,056
sonic hedgehog group medulloblastoma 396 | 1,482
Rheumatoid Arthritis 387 | 1,160
juvenile dermatomyositis 378 | 1,189
Atopic dermatitis 365 | 944
acute quadriplegic myopathy 358 | 1,157
nasopharyngeal carcinoma 353 | 1,056
medulloblastoma 331 | 1,524
esophageal adenocarcinoma 329 | 737
gastric carcinoma 318 | 832
Duchenne muscular dystrophy 315 | 602
dermatomyositis 301 | 933
posterior fossa group B ependymoma 297 | 1,530
Waldenstrons macroglobulinemia 291 | 765
Kidney disease 287 | 396
active Crohn's disease 287 | 918
Obesity 273 | 616
spina bifida 272 | 1,064
atypical teratoid/rhabdoid tumor 271 | 1,095
primary Sjogren syndrome 245 | 789
Alzheimer's disease 237 | 644
autosomal dominant Emery-Dreifuss muscular dystrophy 232 | 499
Prostatic Neoplasms 226 | 471
Multiple Sclerosis 224 | 498
fibroadenoma 219 | 557
Down syndrome 217 | 548
non primary Sjogren syndrome sicca 217 | 840
Arthritis 213 | 248
mucosa-associated lymphoid tissue lymphoma 207 | 480
Atherosclerosis 201 | 275
Mammary Neoplasms 200 | 410
Asthma 199 | 349
Endometriosis 193 | 535
acute myeloid leukemia 192 | 780
Hypertension 191 | 287
Hypersensitivity reaction type II disease 184 | 235
aldosterone-producing adenoma 183 | 664
IGA Glomerulonephritis 180 | 454
Vascular disease 177 | 281
pancreatic carcinoma 176 | 567
Coronary artery disease 173 | 240
non-small cell lung carcinoma 171 | 413
progressive supranuclear palsy 167 | 674
active ulcerative colitis 164 | 477
nephrosclerosis 164 | 329
Cerebrovascular disease 161 | 231
Heart disease 159 | 279
Liver disease 159 | 219
Anemia 157 | 252
Schizophrenia 157 | 501
Stomach Neoplasms 147 | 282
Osteoporosis 146 | 257
Intellectual disability 137 | 573
Parkinson's disease 136 | 364
inflammatory breast cancer 136 | 404

Tissue

Nervous System 4,411 | 18,561
Female tissues 4,404 | 18,647
Digestive Tract 4,400 | 18,473
Endocrine System 4,395 | 18,512
Urinary Tract 4,378 | 18,444
Liver and Pancreas 4,333 | 18,136
Skin and soft tissues 4,316 | 18,115
Cardiovascular System 4,310 | 17,958
Blood and immune system 4,294 | 17,995
Male tissues 4,291 | 17,969
Respiratory system 4,235 | 17,484

Target Family

Non-IDG 2,947 | 11,971
Enzyme 1,246 | 4,146
Kinase 139 | 634
Transporter 97 | 473
Transcription Factor 62 | 1,400
Ion Channel 47 | 341
GPCR 40 | 406
Epigenetic 20 | 242
Nuclear Receptor 6 | 48
TF/Epigenetic 1 | 38
oGPCR 1 | 421

Compartment GO Term

Extracellular region 4,606 | 4,606
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682