Development Level

Tbio 1,853 | 11,651
Tdark 380 | 6,593
Tchem 341 | 1,388
Tclin 157 | 612

Collection

Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Target... 4 | 125
GPCR: IDG Consortium (Targets) 3 | 126
GPCR: IDG Consortium (Complete... 2 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 105 | 979
preweaning lethality, incomple... 81 | 499
decreased vertical activity 56 | 208
enlarged heart 54 | 210
abnormal heart morphology 41 | 162
embryonic lethality prior to t... 39 | 278
abnormal seminal vesicle morph... 30 | 114
abnormal behavior 29 | 298
abnormal embryo size 28 | 220
decreased total body fat amoun... 28 | 207
embryonic lethality prior to o... 26 | 239
abnormal bone structure 24 | 187
hypoactivity 22 | 132
short tibia 22 | 97
cataract 21 | 92
increased total body fat amoun... 21 | 134
decreased bone mineral content 19 | 151
increased circulating alkaline... 19 | 122
decreased circulating glucose ... 18 | 126
increased lean body mass 18 | 172
increased startle reflex 17 | 112
abnormal kidney morphology 16 | 65
decreased body weight 16 | 161
decreased circulating insulin ... 16 | 76
decreased lean body mass 16 | 135
decreased mean corpuscular vol... 16 | 79
improved glucose tolerance 16 | 79
small superior vagus ganglion 16 | 74
embryonic growth retardation 15 | 106
hyperactivity 15 | 148
decreased circulating serum al... 14 | 82
decreased grip strength 14 | 116
decreased lymphocyte cell numb... 14 | 83
increased bone mineral content 14 | 108
increased circulating HDL chol... 14 | 80
increased neutrophil cell numb... 14 | 46
abnormal eye morphology 13 | 68
decreased circulating choleste... 13 | 93
increased mean corpuscular vol... 13 | 92
abnormal lens morphology 12 | 81
decreased body length 12 | 101
decreased startle reflex 12 | 75
impaired glucose tolerance 12 | 75
increased bone mineral density 12 | 72
increased circulating choleste... 12 | 66
increased heart weight 12 | 62
increased leukocyte cell numbe... 12 | 47
small testis 12 | 58
abnormal gait 11 | 69
abnormal retina morphology 11 | 71
abnormal testis morphology 11 | 43
increased lymphocyte cell numb... 11 | 32
increased monocyte cell number 11 | 63
increased or absent threshold ... 11 | 101
abnormal coat-hair pigmentatio... 10 | 64
abnormal sleep behavior 10 | 70
decreased circulating triglyce... 10 | 79
decreased fasted circulating g... 10 | 65
decreased neutrophil cell numb... 10 | 42
hydrometra 10 | 53
increased mean corpuscular hem... 10 | 96
male infertility 10 | 123
prolonged ST segment 10 | 36
abnormal skin morphology 9 | 50
decreased blood urea nitrogen ... 9 | 51
decreased circulating HDL chol... 9 | 68
decreased prepulse inhibition 9 | 82
increased circulating total pr... 9 | 28
increased circulating triglyce... 9 | 42
increased fasted circulating g... 9 | 76
limb grasping 9 | 41
abnormal behavioral response t... 8 | 66
decreased bone mineral density 8 | 126
decreased circulating creatini... 8 | 39
decreased circulating total pr... 8 | 49
decreased erythrocyte cell num... 8 | 62
decreased leukocyte cell numbe... 8 | 73
decreased mean corpuscular hem... 8 | 31
impaired righting response 8 | 26
increased blood urea nitrogen ... 8 | 48
persistence of hyaloid vascula... 8 | 33
prenatal lethality prior to he... 8 | 87
abnormal cranium morphology 7 | 36
abnormal tail morphology 7 | 25
abnormal vibrissa morphology 7 | 25
edema 7 | 59
increased circulating chloride... 7 | 41
increased hematocrit 7 | 46
prolonged QT interval 7 | 38
abnormal epididymis morphology 6 | 42
abnormal retinal vasculature m... 6 | 27
cardiovascular system phenotyp... 6 | 36
decreased circulating aspartat... 6 | 34
decreased circulating free fat... 6 | 31
decreased hematocrit 6 | 46
decreased hemoglobin content 6 | 68
increased circulating calcium ... 6 | 34
increased circulating sodium l... 6 | 71
increased hemoglobin content 6 | 45
increased prepulse inhibition 6 | 32

Disease

Carcinoma 1,518 | 11,493
psoriasis 1,206 | 6,694
ovarian cancer 1,180 | 8,520
osteosarcoma 1,026 | 7,950
glioblastoma 897 | 5,792
lung cancer 878 | 4,740
Cancer 862 | 2,499
medulloblastoma, large-cell 806 | 6,241
ependymoma 677 | 4,679
Breast cancer 670 | 3,578
atypical teratoid / rhabdoid tumor 669 | 5,112
lung carcinoma 646 | 2,843
non-small cell lung cancer 629 | 2,890
lung adenocarcinoma 618 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 617 | 3,291
invasive ductal carcinoma 611 | 2,951
malignant mesothelioma 608 | 3,232
pancreatic cancer 604 | 2,398
Astrocytoma, Pilocytic 600 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 585 | 2,955
adult high grade glioma 579 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 559 | 2,989
interstitial cystitis 555 | 2,312
group 3 medulloblastoma 497 | 4,104
diabetes mellitus 490 | 1,728
cystic fibrosis 476 | 1,696
ulcerative colitis 467 | 1,819
oligodendroglioma 420 | 2,850
pituitary cancer 409 | 1,972
tuberculosis 408 | 2,010
Kidney cancer 395 | 2,613
breast carcinoma 384 | 1,638
ductal carcinoma in situ 379 | 1,745
subependymal giant cell astrocytoma 372 | 2,287
primitive neuroectodermal tumor 365 | 3,035
pancreatic ductal adenocarcinoma liver metastasis 359 | 1,962
Autosomal recessive predisposition 354 | 1,442
astrocytic glioma 351 | 2,597
colon cancer 307 | 1,478
cutaneous lupus erythematosus 299 | 1,057
Schizophrenia 295 | 1,160
primary pancreatic ductal adenocarcinoma 290 | 1,109
adrenocortical carcinoma 283 | 1,428
Atopic dermatitis 273 | 952
Kidney disease 260 | 430
Liver Cirrhosis, Experimental 255 | 769
group 4 medulloblastoma 247 | 1,855
Obesity 241 | 678
juvenile dermatomyositis 237 | 1,187
Rheumatoid arthritis 233 | 1,191
gastric carcinoma 225 | 807
Hypertension 218 | 396
Pick disease 218 | 1,894
nasopharyngeal carcinoma 216 | 1,058
Atherosclerosis 211 | 291
Duchenne muscular dystrophy 211 | 601
astrocytoma 199 | 1,146
Asthma 195 | 385
esophageal adenocarcinoma 187 | 737
acute quadriplegic myopathy 183 | 1,158
Coronary artery disease 180 | 268
Melanoma 180 | 711
Vascular disease 180 | 319
Alzheimer's disease 178 | 658
Arthritis 177 | 290
Multiple myeloma 177 | 1,332
active Crohn's disease 177 | 922
pediatric high grade glioma 177 | 1,064
Multiple Sclerosis 171 | 540
Breast Neoplasms 170 | 445
active ulcerative colitis 168 | 764
Mammary Neoplasms 167 | 425
Prostatic Neoplasms 166 | 495
Bipolar Disorder 163 | 666
fibroadenoma 161 | 559
autosomal dominant Emery-Dreifuss muscular dystrophy 160 | 510
dermatomyositis 157 | 966
Cerebrovascular disease 156 | 238
primary Sjogren syndrome 156 | 735
Heart disease 151 | 306
Endometriosis 149 | 540
Depressive disorder 148 | 409
mucosa-associated lymphoid tissue lymphoma 148 | 484
Epilepsy 147 | 792
Intellectual disability 143 | 1,016
Osteoporosis 143 | 363
Anemia 137 | 365
spina bifida 136 | 1,074
Hypertensive disease 135 | 292
Liver disease 135 | 237
Hypersensitivity reaction type II disease 134 | 253
Skin cancer 131 | 469
Seizures 130 | 596
non primary Sjogren syndrome sicca 129 | 891
Lung disease 125 | 142
Liver cancer 124 | 604
Down syndrome 123 | 499
Short stature 121 | 531
Waldenstrons macroglobulinemia 119 | 765
Diarrhea 115 | 253

Tissue

Endocrine System 2,558 | 18,159
Digestive Tract 2,500 | 17,369
Female tissues 2,487 | 17,400
Skin and soft tissues 2,451 | 17,230
Male tissues 2,445 | 17,142
Blood and immune system 2,401 | 16,909
Liver and Pancreas 2,377 | 16,750
Urinary Tract 2,354 | 16,678
Nervous System 2,289 | 16,725
Respiratory system 2,275 | 16,393
Cardiovascular System 2,022 | 15,192

Target Family

Non-IDG 1,896 | 12,091
Enzyme 607 | 4,145
Kinase 86 | 634
Transcription Factor 57 | 1,400
GPCR 31 | 408
Ion Channel 23 | 344
Transporter 19 | 473
Nuclear Receptor 8 | 48
Epigenetic 4 | 242

Compartment GO Term

Extracellular region 2,731 | 2,731
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Kallikrein-9 KLK9 Tbio Enzyme -0.89030 8.64 143
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
Kallikrein-12 KLK12 Tbio Enzyme -0.99694 11.0 111
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895