Development Level

Tbio 1,982 | 10,625
Tchem 461 | 1,890
Tdark 283 | 7,003
Tclin 124 | 602

Collection

Eligible Ion Channel Proteins 13 | 117
Eligible Kinase Proteins 7 | 134
Eligible non-olfactory GPCR Proteins 5 | 143

IMPC Term

preweaning lethality, complete... 113 | 633
abnormal behavior 47 | 226
preweaning lethality, incomple... 44 | 260
decreased lean body mass 42 | 195
embryonic lethality prior to t... 41 | 187
decreased total body fat amoun... 36 | 186
embryonic lethality prior to o... 34 | 148
decreased bone mineral content 29 | 157
decreased grip strength 29 | 123
increased circulating alkaline... 28 | 119
increased or absent threshold ... 27 | 128
abnormal bone structure 26 | 131
enlarged heart 26 | 111
decreased body weight 25 | 174
decreased body length 23 | 108
decreased bone mineral density 23 | 126
hyperactivity 22 | 108
abnormal embryo size 21 | 112
hypoactivity 21 | 89
increased mean corpuscular vol... 21 | 91
abnormal retina morphology 20 | 100
increased mean corpuscular hem... 20 | 93
short tibia 20 | 82
decreased circulating insulin ... 19 | 75
abnormal lens morphology 17 | 73
decreased mean corpuscular vol... 16 | 50
impaired glucose tolerance 16 | 52
increased lean body mass 16 | 107
decreased circulating glucose ... 15 | 121
increased bone mineral content 15 | 92
abnormal bone mineralization 14 | 55
decreased circulating triglyce... 14 | 83
increased exploration in new e... 14 | 56
decreased circulating HDL chol... 13 | 77
decreased hemoglobin content 13 | 53
improved glucose tolerance 13 | 56
increased fasted circulating g... 13 | 68
abnormal retinal pigmentation 12 | 61
abnormal seminal vesicle morph... 12 | 47
increased blood urea nitrogen ... 12 | 44
increased grip strength 12 | 83
decreased circulating serum al... 11 | 79
decreased erythrocyte cell num... 11 | 43
decreased leukocyte cell numbe... 11 | 54
decreased startle reflex 11 | 48
abnormal QRS complex 10 | 25
abnormal heart morphology 10 | 51
decreased circulating choleste... 10 | 85
decreased threshold for audito... 10 | 32
increased circulating sodium l... 10 | 71
male infertility 10 | 62
prenatal lethality prior to he... 10 | 64
abnormal neural tube closure 9 | 37
decreased circulating alkaline... 9 | 41
decreased heart weight 9 | 44
decreased mean corpuscular hem... 9 | 34
cardiovascular system phenotyp... 8 | 35
decreased caudal vertebrae num... 8 | 49
decreased eosinophil cell numb... 8 | 41
decreased lumbar vertebrae num... 8 | 62
decreased prepulse inhibition 8 | 52
decreased rib number 8 | 59
enlarged epididymis 8 | 27
increased bone mineral density 8 | 52
increased circulating chloride... 8 | 43
increased heart weight 8 | 37
increased hematocrit 8 | 36
increased sacral vertebrae num... 8 | 62
small testis 8 | 37
abnormal cranium morphology 7 | 32
abnormal kidney morphology 7 | 30
corneal opacity 7 | 25
decreased circulating alanine ... 7 | 53
immune system phenotype 7 | 17
increased hemoglobin content 7 | 45
increased leukocyte cell numbe... 7 | 37
increased red blood cell distr... 7 | 21
increased total body fat amoun... 7 | 57
thrombocytopenia 7 | 46
abnormal body wall morphology 6 | 7
abnormal cornea morphology 6 | 24
abnormal epididymis morphology 6 | 31
abnormal skin morphology 6 | 23
abnormal sleep behavior 6 | 63
abnormal testis morphology 6 | 30
decreased circulating free fat... 6 | 39
decreased circulating glycerol... 6 | 19
decreased circulating total pr... 6 | 41
decreased fasted circulating g... 6 | 49
enlarged lymph nodes 6 | 27
enlarged spleen 6 | 26
increased body weight 6 | 42
increased circulating HDL chol... 6 | 63
increased circulating choleste... 6 | 53
increased circulating iron lev... 6 | 25
abnormal coat/hair pigmentatio... 5 | 54
abnormal gait 5 | 51
abnormal lung morphology 5 | 15
increased circulating potassiu... 5 | 31
increased circulating total pr... 5 | 20

Disease

ovarian cancer 1,581 | 8,484
psoriasis 1,241 | 6,685
osteosarcoma 1,220 | 7,933
medulloblastoma, large-cell 969 | 6,234
glioblastoma 966 | 5,572
lung cancer 948 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 701 | 3,289
Cancer 692 | 2,346
atypical teratoid / rhabdoid tumor 686 | 4,369
invasive ductal carcinoma 632 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 630 | 2,956
Breast cancer 623 | 3,094
malignant mesothelioma 622 | 3,162
pancreatic cancer 619 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 617 | 2,988
lung adenocarcinoma 599 | 2,713
non-small cell lung cancer 590 | 2,798
lung carcinoma 588 | 2,844
pilocytic astrocytoma 584 | 3,086
pediatric high grade glioma 480 | 2,712
ulcerative colitis 478 | 2,087
interstitial cystitis 476 | 2,299
oligodendroglioma 468 | 2,849
diabetes mellitus 463 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 462 | 1,795
primitive neuroectodermal tumor 455 | 3,031
subependymal giant cell astrocytoma 439 | 2,287
ependymoma 428 | 2,514
Multiple myeloma 422 | 1,327
breast carcinoma 386 | 1,614
ductal carcinoma in situ 383 | 1,745
cystic fibrosis 382 | 1,665
primary pancreatic ductal adenocarcinoma 365 | 1,271
Carcinoma 351 | 2,147
astrocytoma 349 | 1,493
tuberculosis 348 | 1,557
astrocytic glioma 343 | 2,241
pituitary cancer 342 | 1,972
colon cancer 341 | 1,475
Pick disease 333 | 1,893
adult high grade glioma 323 | 2,148
group 3 medulloblastoma 306 | 2,254
group 4 medulloblastoma 299 | 1,875
posterior fossa group A ependymoma 279 | 1,511
acute quadriplegic myopathy 272 | 1,157
juvenile dermatomyositis 270 | 1,189
Rheumatoid Arthritis 259 | 1,160
Waldenstrons macroglobulinemia 257 | 765
adrenocortical carcinoma 257 | 1,427
esophageal adenocarcinoma 245 | 737
sonic hedgehog group medulloblastoma 244 | 1,482
medulloblastoma 242 | 1,524
dermatomyositis 240 | 933
Duchenne muscular dystrophy 235 | 602
nasopharyngeal carcinoma 232 | 1,056
cutaneous lupus erythematosus 224 | 1,056
gastric carcinoma 216 | 832
Atopic dermatitis 215 | 944
spina bifida 193 | 1,064
active Crohn's disease 187 | 918
posterior fossa group B ependymoma 179 | 1,530
atypical teratoid/rhabdoid tumor 177 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 168 | 499
Kidney disease 164 | 396
Prostatic Neoplasms 158 | 471
acute myeloid leukemia 154 | 780
Down syndrome 149 | 548
non primary Sjogren syndrome sicca 149 | 840
primary Sjogren syndrome 145 | 789
Alzheimer's disease 144 | 644
Obesity 140 | 616
aldosterone-producing adenoma 129 | 664
fibroadenoma 128 | 557
mucosa-associated lymphoid tissue lymphoma 127 | 480
IGA Glomerulonephritis 126 | 454
Multiple Sclerosis 123 | 498
nephrosclerosis 120 | 329
active ulcerative colitis 119 | 477
pancreatic carcinoma 119 | 567
progressive supranuclear palsy 116 | 674
Arthritis 115 | 248
Hypersensitivity reaction type II disease 111 | 235
Endometriosis 105 | 535
non-small cell lung carcinoma 104 | 413
Anemia 102 | 252
Neurodegenerative disease 102 | 383
tuberculosis and treatment for 6 months 99 | 686
Hypertension 98 | 287
Vascular disease 98 | 281
Liver disease 96 | 219
Mammary Neoplasms 96 | 410
Atherosclerosis 95 | 275
Becker muscular dystrophy 93 | 187
Intellectual disability 92 | 573
Stomach Neoplasms 90 | 282
chronic rhinosinusitis 90 | 512
Ankylosing spondylitis 89 | 138
Polycystic Ovary Syndrome 87 | 332
Schizophrenia 87 | 501
hepatocellular carcinoma 87 | 532

Tissue

Female tissues 2,742 | 18,647
Nervous System 2,742 | 18,561
Digestive Tract 2,741 | 18,473
Urinary Tract 2,737 | 18,444
Liver and Pancreas 2,736 | 18,136
Endocrine System 2,735 | 18,512
Blood and immune system 2,732 | 17,995
Male tissues 2,730 | 17,969
Cardiovascular System 2,729 | 17,958
Respiratory system 2,713 | 17,484
Skin and soft tissues 2,697 | 18,115

Target Family

Non-IDG 1,663 | 11,971
Enzyme 932 | 4,146
Kinase 89 | 634
Transporter 82 | 473
Ion Channel 35 | 341
Transcription Factor 20 | 1,400
GPCR 14 | 406
Epigenetic 13 | 242
Nuclear Receptor 1 | 48
oGPCR 1 | 421

Compartment GO Term

Extracellular organelle 2,850 | 2,850
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Antileukoproteinase SLPI Tbio Enzyme -2.56514 434.2 290
Endoplasmin HSP90B1 Tchem Non-IDG -2.72785 604.5 748