Development Level

Tbio 278 | 11,445
Tchem 86 | 1,598
Tclin 32 | 613
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 25 | 979
enlarged heart 15 | 210
preweaning lethality, incomple... 14 | 499
embryonic lethality prior to t... 12 | 278
abnormal heart morphology 9 | 162
abnormal embryo size 8 | 220
decreased vertical activity 8 | 208
abnormal seminal vesicle morph... 6 | 114
decreased body weight 6 | 161
decreased total body fat amoun... 6 | 207
embryonic lethality prior to o... 6 | 239
abnormal behavior 5 | 298
abnormal bone structure 5 | 187
abnormal coat-hair pigmentatio... 5 | 64
decreased body length 5 | 101
decreased bone mineral content 5 | 151
decreased erythrocyte cell num... 5 | 62
abnormal lung morphology 4 | 26
abnormal testis morphology 4 | 43
abnormal tooth morphology 4 | 24
decreased lean body mass 4 | 135
impaired glucose tolerance 4 | 75
increased heart weight 4 | 62
increased neutrophil cell numb... 4 | 46
increased total body fat amoun... 4 | 134
short tibia 4 | 97
abnormal cranium morphology 3 | 36
abnormal eye morphology 3 | 68
abnormal femur morphology 3 | 14
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased circulating choleste... 3 | 93
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased heart weight 3 | 27
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular hem... 3 | 50
increased bone mineral content 3 | 108
increased circulating alkaline... 3 | 122
increased circulating triglyce... 3 | 42
increased startle reflex 3 | 112
limb grasping 3 | 41
male infertility 3 | 123
persistence of hyaloid vascula... 3 | 33
small superior vagus ganglion 3 | 74
small testis 3 | 58
abnormal behavioral response t... 2 | 66
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal head size 2 | 6
abnormal humerus morphology 2 | 11
abnormal liver morphology 2 | 17
abnormal midbrain development 2 | 20
abnormal neural tube closure 2 | 46
abnormal placement of pupils 2 | 6
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
abnormal snout morphology 2 | 23
abnormal spleen morphology 2 | 55
abnormal tail morphology 2 | 25
abnormal vibrissa morphology 2 | 25
decreased blood urea nitrogen ... 2 | 51
decreased circulating HDL chol... 2 | 68
decreased circulating aspartat... 2 | 34
decreased circulating bilirubi... 2 | 19
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased circulating sodium l... 2 | 22
decreased circulating total pr... 2 | 49
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
enlarged spleen 2 | 41
enlarged uterus 2 | 11
female infertility 2 | 60
hydrometra 2 | 53
hypoactivity 2 | 132
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased bone mineral density 2 | 72
increased circulating choleste... 2 | 66
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased large unstained cell... 2 | 5
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased red blood cell distr... 2 | 34
mammalian phenotype 2 | 17
narrow eye opening 2 | 12
pallor 2 | 34
thrombocytopenia 2 | 56
decreased eosinophil cell numb... 1 | 24
decreased neutrophil cell numb... 1 | 42

Disease

Carcinoma 288 | 11,493
Cancer 263 | 2,499
ovarian cancer 239 | 8,520
psoriasis 220 | 6,694
glioblastoma 203 | 5,792
lung cancer 195 | 4,740
osteosarcoma 188 | 7,950
Breast cancer 178 | 3,578
malignant mesothelioma 170 | 3,232
atypical teratoid / rhabdoid tumor 156 | 5,112
invasive ductal carcinoma 155 | 2,951
ependymoma 154 | 4,679
pancreatic cancer 152 | 2,398
non-small cell lung cancer 150 | 2,890
lung carcinoma 148 | 2,843
medulloblastoma, large-cell 145 | 6,241
Astrocytoma, Pilocytic 143 | 3,081
interstitial cystitis 142 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 137 | 2,955
diabetes mellitus 130 | 1,728
lung adenocarcinoma 130 | 2,716
adult high grade glioma 129 | 3,801
cystic fibrosis 127 | 1,696
ulcerative colitis 121 | 1,819
intraductal papillary-mucinous neoplasm (IPMN) 117 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 115 | 2,989
Kidney disease 112 | 430
Kidney cancer 107 | 2,613
breast carcinoma 97 | 1,638
ductal carcinoma in situ 97 | 1,745
pituitary cancer 94 | 1,972
tuberculosis 93 | 2,010
Autosomal recessive predisposition 88 | 1,442
Liver Cirrhosis, Experimental 86 | 769
Arthritis 83 | 290
group 3 medulloblastoma 82 | 4,104
oligodendroglioma 81 | 2,850
primary pancreatic ductal adenocarcinoma 81 | 1,109
primitive neuroectodermal tumor 80 | 3,035
Heart disease 79 | 306
subependymal giant cell astrocytoma 78 | 2,287
Asthma 77 | 385
Atherosclerosis 77 | 291
Hypersensitivity reaction type II disease 77 | 253
Schizophrenia 73 | 1,160
colon cancer 73 | 1,478
Hypertension 72 | 396
cutaneous lupus erythematosus 72 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 72 | 1,962
Rheumatoid arthritis 70 | 1,191
Duchenne muscular dystrophy 68 | 601
gastric carcinoma 68 | 807
Breast Neoplasms 67 | 445
Mammary Neoplasms 66 | 425
adrenocortical carcinoma 66 | 1,428
Multiple Sclerosis 65 | 540
Obesity 65 | 678
nasopharyngeal carcinoma 65 | 1,058
Inflammatory bowel disease 64 | 151
Lung disease 64 | 142
juvenile dermatomyositis 64 | 1,187
Vascular disease 63 | 319
group 4 medulloblastoma 63 | 1,855
Coronary artery disease 62 | 268
Melanoma 61 | 711
astrocytic glioma 61 | 2,597
Liver disease 60 | 237
Cerebrovascular disease 59 | 238
Atopic dermatitis 57 | 952
autosomal dominant Emery-Dreifuss muscular dystrophy 57 | 510
Anemia 56 | 365
Hypertensive disease 55 | 292
Prostatic Neoplasms 53 | 495
esophageal adenocarcinoma 52 | 737
Alzheimer's disease 51 | 658
Dermatitis 50 | 157
Endometriosis 50 | 540
acute quadriplegic myopathy 50 | 1,158
Neoplasm Invasiveness 49 | 161
Neoplasm Metastasis 49 | 168
Pulmonary Fibrosis 49 | 106
Stomach Neoplasms 49 | 300
Osteoporosis 48 | 363
periodontitis 48 | 293
Skin cancer 45 | 469
active ulcerative colitis 44 | 764
Allergic hypersensitivity disease 43 | 126
Lung Neoplasms 43 | 232
Osteoarthritis 43 | 184
pediatric high grade glioma 43 | 1,064
Carcinoma, Hepatocellular 42 | 228
Liver Cirrhosis 42 | 181
Liver cancer 41 | 604
Liver carcinoma 41 | 240
Short stature 41 | 531
Bipolar Disorder 39 | 666
Inflammation 39 | 120
astrocytoma 39 | 1,146
Neuropathy 38 | 261
limb girdle muscular dystrophy 2A 38 | 213

Tissue

Endocrine System 390 | 18,159
Digestive Tract 387 | 17,369
Skin and soft tissues 382 | 17,230
Female tissues 380 | 17,400
Male tissues 380 | 17,142
Urinary Tract 380 | 16,678
Liver and Pancreas 378 | 16,750
Blood and immune system 377 | 16,909
Respiratory system 373 | 16,393
Nervous System 372 | 16,725
Cardiovascular System 341 | 15,192

Target Family

Non-IDG 269 | 12,091
Enzyme 66 | 4,145
Transcription Factor 32 | 1,400
Kinase 30 | 634
GPCR 2 | 408
Nuclear Receptor 2 | 48
Transporter 1 | 473

Compartment GO Term

Extracellular matrix component 402 | 402
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128