Development Level

Tbio 438 | 10,625
Tchem 137 | 1,890
Tclin 30 | 602
Tdark 28 | 7,003

IMPC Term

preweaning lethality, complete... 29 | 633
decreased lean body mass 10 | 195
decreased body weight 9 | 174
embryonic lethality prior to t... 9 | 187
preweaning lethality, incomple... 8 | 260
short tibia 8 | 82
abnormal behavior 7 | 226
decreased body length 7 | 108
decreased bone mineral content 7 | 157
decreased grip strength 7 | 123
decreased total body fat amoun... 7 | 186
abnormal embryo size 6 | 112
abnormal lens morphology 6 | 73
decreased bone mineral density 6 | 126
enlarged heart 6 | 111
increased circulating alkaline... 6 | 119
increased or absent threshold ... 6 | 128
abnormal coat/hair pigmentatio... 5 | 54
abnormal femur morphology 5 | 14
abnormal retina morphology 5 | 100
embryonic lethality prior to o... 5 | 148
abnormal bone mineralization 4 | 55
abnormal bone structure 4 | 131
abnormal heart morphology 4 | 51
abnormal sleep behavior 4 | 63
abnormal tooth morphology 4 | 24
decreased circulating glucose ... 4 | 121
decreased circulating insulin ... 4 | 75
decreased circulating serum al... 4 | 79
decreased erythrocyte cell num... 4 | 43
decreased heart weight 4 | 44
decreased leukocyte cell numbe... 4 | 54
impaired glucose tolerance 4 | 52
increased circulating HDL chol... 4 | 63
increased circulating choleste... 4 | 53
increased mean corpuscular vol... 4 | 91
abnormal humerus morphology 3 | 11
abnormal radius morphology 3 | 8
abnormal retinal blood vessel ... 3 | 18
abnormal seminal vesicle morph... 3 | 47
abnormal tibia morphology 3 | 14
abnormal ulna morphology 3 | 8
cataract 3 | 26
decreased circulating free fat... 3 | 39
decreased hemoglobin content 3 | 53
decreased mean corpuscular hem... 3 | 34
decreased mean corpuscular vol... 3 | 50
decreased threshold for audito... 3 | 32
impaired righting response 3 | 19
increased blood urea nitrogen ... 3 | 44
increased bone mineral content 3 | 92
increased bone mineral density 3 | 52
increased exploration in new e... 3 | 56
increased fasted circulating g... 3 | 68
increased hemoglobin content 3 | 45
mydriasis 3 | 9
persistence of hyaloid vascula... 3 | 22
abnormal behavioral response t... 2 | 52
abnormal coping response 2 | 12
abnormal cranium morphology 2 | 32
abnormal eye morphology 2 | 38
abnormal gait 2 | 51
abnormal iris morphology 2 | 12
abnormal kidney morphology 2 | 30
abnormal neural tube closure 2 | 37
abnormal pelvic girdle bone mo... 2 | 11
abnormal retinal pigmentation 2 | 61
abnormal retinal vasculature m... 2 | 15
abnormal snout morphology 2 | 18
abnormal testis morphology 2 | 30
decreased blood urea nitrogen ... 2 | 31
decreased caudal vertebrae num... 2 | 49
decreased circulating choleste... 2 | 85
decreased circulating total pr... 2 | 41
decreased circulating triglyce... 2 | 83
decreased hematocrit 2 | 25
decreased mean corpuscular hem... 2 | 19
decreased prepulse inhibition 2 | 52
enlarged spleen 2 | 26
hydrops fetalis 2 | 22
hyperactivity 2 | 108
improved glucose tolerance 2 | 56
increased body length 2 | 20
increased circulating bilirubi... 2 | 16
increased circulating calcium ... 2 | 32
increased circulating potassiu... 2 | 31
increased circulating triglyce... 2 | 24
increased erythrocyte cell num... 2 | 26
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased total body fat amoun... 2 | 57
increased vertical activity 2 | 18
limb grasping 2 | 35
male infertility 2 | 62
polycystic kidney 2 | 9
polydactyly 2 | 22
premature death 2 | 5
small testis 2 | 37
thrombocytopenia 2 | 46
thrombocytosis 2 | 23

Disease

ovarian cancer 368 | 8,484
psoriasis 302 | 6,685
Cancer 290 | 2,346
glioblastoma 267 | 5,572
osteosarcoma 266 | 7,933
lung cancer 242 | 4,466
medulloblastoma, large-cell 219 | 6,234
pancreatic cancer 205 | 2,300
non-small cell lung cancer 204 | 2,798
invasive ductal carcinoma 203 | 2,950
lung adenocarcinoma 203 | 2,713
pilocytic astrocytoma 198 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 196 | 2,956
Breast cancer 193 | 3,094
lung carcinoma 193 | 2,844
malignant mesothelioma 190 | 3,162
atypical teratoid / rhabdoid tumor 186 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 183 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 179 | 3,289
ulcerative colitis 169 | 2,087
cystic fibrosis 167 | 1,665
interstitial cystitis 166 | 2,299
diabetes mellitus 156 | 1,663
pediatric high grade glioma 155 | 2,712
Carcinoma 147 | 2,147
breast carcinoma 143 | 1,614
primary pancreatic ductal adenocarcinoma 140 | 1,271
ductal carcinoma in situ 132 | 1,745
posterior fossa group A ependymoma 130 | 1,511
pituitary cancer 129 | 1,972
oligodendroglioma 124 | 2,849
sonic hedgehog group medulloblastoma 112 | 1,482
Kidney disease 110 | 396
primitive neuroectodermal tumor 110 | 3,031
subependymal giant cell astrocytoma 108 | 2,287
Duchenne muscular dystrophy 104 | 602
colon cancer 103 | 1,475
gastric carcinoma 100 | 832
adrenocortical carcinoma 98 | 1,427
ependymoma 93 | 2,514
tuberculosis 86 | 1,557
juvenile dermatomyositis 85 | 1,189
Atopic dermatitis 82 | 944
group 4 medulloblastoma 80 | 1,875
nasopharyngeal carcinoma 80 | 1,056
autosomal dominant Emery-Dreifuss muscular dystrophy 79 | 499
cutaneous lupus erythematosus 79 | 1,056
Arthritis 76 | 248
adult high grade glioma 75 | 2,148
astrocytoma 75 | 1,493
Heart disease 74 | 279
pancreatic ductal adenocarcinoma liver metastasis 73 | 1,795
Atherosclerosis 72 | 275
acute quadriplegic myopathy 72 | 1,157
astrocytic glioma 70 | 2,241
esophageal adenocarcinoma 70 | 737
Rheumatoid Arthritis 69 | 1,160
group 3 medulloblastoma 69 | 2,254
Alzheimer's disease 68 | 644
Mammary Neoplasms 65 | 410
Cerebrovascular disease 63 | 231
Hypertension 61 | 287
Prostatic Neoplasms 60 | 471
fibroadenoma 59 | 557
Multiple myeloma 58 | 1,327
Lung disease 56 | 132
Liver disease 55 | 219
Obesity 55 | 616
Vascular disease 55 | 281
dermatomyositis 55 | 933
Coronary artery disease 53 | 240
Neoplasm Invasiveness 53 | 127
Becker muscular dystrophy 52 | 187
Down syndrome 52 | 548
Endometriosis 52 | 535
interstitial lung disease 52 | 291
Osteoporosis 51 | 257
Neoplasm Metastasis 50 | 138
Pick disease 50 | 1,893
Asthma 49 | 349
Multiple Sclerosis 48 | 498
mucosa-associated lymphoid tissue lymphoma 48 | 480
Hypersensitivity reaction type II disease 47 | 235
atypical teratoid/rhabdoid tumor 47 | 1,095
posterior fossa group B ependymoma 47 | 1,530
limb girdle muscular dystrophy 2A 46 | 156
Osteoarthritis 44 | 96
Stomach Neoplasms 44 | 282
Waldenstrons macroglobulinemia 44 | 765
active Crohn's disease 42 | 918
primary Sjogren syndrome 42 | 789
Inflammatory bowel disease 40 | 142
Liver carcinoma 40 | 217
Lung Neoplasms 39 | 171
inflammatory breast cancer 39 | 404
periodontitis 39 | 269
Parkinson's disease 38 | 364
non-small cell lung carcinoma 38 | 413
Spontaneous abortion 37 | 108
non primary Sjogren syndrome sicca 37 | 840

Tissue

Digestive Tract 626 | 18,473
Endocrine System 626 | 18,512
Female tissues 626 | 18,647
Nervous System 624 | 18,561
Urinary Tract 624 | 18,444
Skin and soft tissues 621 | 18,115
Liver and Pancreas 619 | 18,136
Cardiovascular System 618 | 17,958
Male tissues 617 | 17,969
Blood and immune system 615 | 17,995
Respiratory system 609 | 17,484

Target Family

Non-IDG 471 | 11,971
Enzyme 118 | 4,146
Kinase 23 | 634
Transcription Factor 16 | 1,400
Transporter 3 | 473
GPCR 1 | 406
Nuclear Receptor 1 | 48

Compartment GO Term

Extracellular matrix 633 | 633
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682