Development Level

Tbio 515 | 11,445
Tchem 119 | 1,598
Tclin 43 | 613
Tdark 37 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 34 | 979
preweaning lethality, incomple... 20 | 499
enlarged heart 17 | 210
embryonic lethality prior to t... 16 | 278
abnormal heart morphology 12 | 162
decreased vertical activity 12 | 208
short tibia 11 | 97
abnormal behavior 9 | 298
abnormal embryo size 9 | 220
abnormal seminal vesicle morph... 9 | 114
decreased body weight 9 | 161
embryonic lethality prior to o... 9 | 239
abnormal bone structure 8 | 187
decreased body length 8 | 101
cataract 7 | 92
decreased bone mineral content 7 | 151
decreased total body fat amoun... 7 | 207
increased circulating alkaline... 7 | 122
increased neutrophil cell numb... 7 | 46
increased total body fat amoun... 7 | 134
abnormal coat-hair pigmentatio... 6 | 64
abnormal lens morphology 6 | 81
decreased erythrocyte cell num... 6 | 62
decreased lean body mass 6 | 135
increased heart weight 6 | 62
abnormal femur morphology 5 | 14
abnormal kidney morphology 5 | 65
abnormal testis morphology 5 | 43
decreased circulating serum al... 5 | 82
decreased lymphocyte cell numb... 5 | 83
decreased mean corpuscular vol... 5 | 79
increased or absent threshold ... 5 | 101
abnormal cranium morphology 4 | 36
abnormal eye morphology 4 | 68
abnormal lung morphology 4 | 26
abnormal retina morphology 4 | 71
abnormal tooth morphology 4 | 24
decreased blood urea nitrogen ... 4 | 51
decreased bone mineral density 4 | 126
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
decreased circulating triglyce... 4 | 79
decreased neutrophil cell numb... 4 | 42
impaired glucose tolerance 4 | 75
increased bone mineral content 4 | 108
increased circulating triglyce... 4 | 42
increased startle reflex 4 | 112
mammalian phenotype 4 | 17
persistence of hyaloid vascula... 4 | 33
small superior vagus ganglion 4 | 74
small testis 4 | 58
abnormal bone mineralization 3 | 38
abnormal humerus morphology 3 | 11
abnormal radius morphology 3 | 8
abnormal skin morphology 3 | 50
abnormal sleep behavior 3 | 70
abnormal tail morphology 3 | 25
abnormal tibia morphology 3 | 14
abnormal ulna morphology 3 | 8
decreased circulating free fat... 3 | 31
decreased circulating insulin ... 3 | 76
decreased circulating phosphat... 3 | 27
decreased grip strength 3 | 116
decreased heart weight 3 | 27
decreased hemoglobin content 3 | 68
decreased leukocyte cell numbe... 3 | 73
decreased mean corpuscular hem... 3 | 50
decreased startle reflex 3 | 75
embryonic growth retardation 3 | 106
enlarged kidney 3 | 14
enlarged spleen 3 | 41
hyperactivity 3 | 148
impaired pupillary reflex 3 | 26
impaired righting response 3 | 26
improved glucose tolerance 3 | 79
increased bone mineral density 3 | 72
increased circulating choleste... 3 | 66
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased red blood cell distr... 3 | 34
limb grasping 3 | 41
male infertility 3 | 123
narrow eye opening 3 | 12
thrombocytopenia 3 | 56
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal liver morphology 2 | 17
abnormal skin coloration 2 | 25
abnormal vibrissa morphology 2 | 25
anophthalmia 2 | 33
corneal opacity 2 | 32
decreased circulating calcium ... 2 | 36
decreased circulating creatini... 2 | 39
decreased hematocrit 2 | 46
decreased prepulse inhibition 2 | 82
hypoactivity 2 | 132
increased circulating bilirubi... 2 | 16
increased fasted circulating g... 2 | 76
increased large unstained cell... 2 | 5
increased lean body mass 2 | 172

Disease

Carcinoma 506 | 11,493
ovarian cancer 390 | 8,520
Cancer 375 | 2,499
psoriasis 365 | 6,694
glioblastoma 329 | 5,792
osteosarcoma 305 | 7,950
lung cancer 292 | 4,740
Breast cancer 273 | 3,578
ependymoma 254 | 4,679
medulloblastoma, large-cell 249 | 6,241
invasive ductal carcinoma 246 | 2,951
atypical teratoid / rhabdoid tumor 243 | 5,112
malignant mesothelioma 241 | 3,232
pancreatic cancer 238 | 2,398
non-small cell lung cancer 230 | 2,890
lung carcinoma 228 | 2,843
Astrocytoma, Pilocytic 227 | 3,081
lung adenocarcinoma 220 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 219 | 2,955
interstitial cystitis 212 | 2,312
adult high grade glioma 209 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 198 | 2,989
cystic fibrosis 193 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 192 | 3,291
ulcerative colitis 183 | 1,819
diabetes mellitus 178 | 1,728
Kidney cancer 167 | 2,613
breast carcinoma 161 | 1,638
ductal carcinoma in situ 159 | 1,745
pituitary cancer 146 | 1,972
group 3 medulloblastoma 144 | 4,104
Autosomal recessive predisposition 140 | 1,442
oligodendroglioma 136 | 2,850
Kidney disease 134 | 430
primitive neuroectodermal tumor 131 | 3,035
primary pancreatic ductal adenocarcinoma 128 | 1,109
tuberculosis 128 | 2,010
colon cancer 119 | 1,478
subependymal giant cell astrocytoma 119 | 2,287
Liver Cirrhosis, Experimental 110 | 769
astrocytic glioma 110 | 2,597
Schizophrenia 108 | 1,160
adrenocortical carcinoma 108 | 1,428
Duchenne muscular dystrophy 105 | 601
Arthritis 104 | 290
Atopic dermatitis 102 | 952
cutaneous lupus erythematosus 102 | 1,057
Atherosclerosis 100 | 291
gastric carcinoma 100 | 807
pancreatic ductal adenocarcinoma liver metastasis 99 | 1,962
nasopharyngeal carcinoma 97 | 1,058
Breast Neoplasms 96 | 445
juvenile dermatomyositis 96 | 1,187
Mammary Neoplasms 95 | 425
Heart disease 93 | 306
Hypertension 93 | 396
group 4 medulloblastoma 92 | 1,855
autosomal dominant Emery-Dreifuss muscular dystrophy 91 | 510
Asthma 90 | 385
Obesity 90 | 678
Melanoma 87 | 711
Rheumatoid arthritis 86 | 1,191
Vascular disease 86 | 319
Coronary artery disease 84 | 268
Hypersensitivity reaction type II disease 83 | 253
Multiple Sclerosis 80 | 540
Prostatic Neoplasms 78 | 495
Lung disease 75 | 142
Cerebrovascular disease 73 | 238
Liver disease 72 | 237
Short stature 70 | 531
esophageal adenocarcinoma 70 | 737
acute quadriplegic myopathy 69 | 1,158
Alzheimer's disease 68 | 658
Hypertensive disease 68 | 292
Anemia 67 | 365
Endometriosis 67 | 540
Inflammatory bowel disease 67 | 151
Osteoporosis 67 | 363
fibroadenoma 67 | 559
Liver cancer 66 | 604
Osteoarthritis 66 | 184
Neoplasm Invasiveness 63 | 161
Skin cancer 63 | 469
pediatric high grade glioma 63 | 1,064
Lung Neoplasms 62 | 232
Stomach Neoplasms 62 | 300
Neoplasm Metastasis 61 | 168
astrocytoma 60 | 1,146
Pick disease 59 | 1,894
active ulcerative colitis 58 | 764
limb girdle muscular dystrophy 2A 56 | 213
Pulmonary Fibrosis 55 | 106
periodontitis 55 | 293
Dermatitis 54 | 157
Bipolar Disorder 53 | 666
Carcinoma, Hepatocellular 53 | 228
Down syndrome 53 | 499
interstitial lung disease 53 | 298
Intellectual disability 52 | 1,016

Tissue

Endocrine System 690 | 18,159
Digestive Tract 678 | 17,369
Female tissues 675 | 17,400
Skin and soft tissues 671 | 17,230
Male tissues 669 | 17,142
Blood and immune system 661 | 16,909
Urinary Tract 661 | 16,678
Liver and Pancreas 655 | 16,750
Nervous System 652 | 16,725
Respiratory system 636 | 16,393
Cardiovascular System 580 | 15,192

Target Family

Non-IDG 503 | 12,091
Enzyme 124 | 4,145
Transcription Factor 38 | 1,400
Kinase 37 | 634
GPCR 4 | 408
Ion Channel 3 | 344
Nuclear Receptor 3 | 48
Epigenetic 1 | 242
Transporter 1 | 473

Compartment GO Term

Extracellular matrix 714 | 714
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Spondin-2 SPON2 Tbio Non-IDG -1.73555 56.2 210
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Matrix metalloproteinase-24 MMP24 Tbio Enzyme -1.38282 25.8 147