Development Level

Tbio 520 | 11,651
Tchem 113 | 1,388
Tclin 43 | 612
Tdark 37 | 6,593

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 34 | 979
preweaning lethality, incomple... 20 | 499
enlarged heart 17 | 210
embryonic lethality prior to t... 16 | 278
abnormal heart morphology 12 | 162
decreased vertical activity 12 | 208
short tibia 11 | 97
abnormal behavior 9 | 298
abnormal embryo size 9 | 220
abnormal seminal vesicle morph... 9 | 114
decreased body weight 9 | 161
embryonic lethality prior to o... 9 | 239
abnormal bone structure 8 | 187
decreased body length 8 | 101
cataract 7 | 92
decreased bone mineral content 7 | 151
decreased total body fat amoun... 7 | 207
increased circulating alkaline... 7 | 122
increased neutrophil cell numb... 7 | 46
increased total body fat amoun... 7 | 134
abnormal coat-hair pigmentatio... 6 | 64
abnormal lens morphology 6 | 81
decreased erythrocyte cell num... 6 | 62
decreased lean body mass 6 | 135
increased heart weight 6 | 62
abnormal femur morphology 5 | 14
abnormal kidney morphology 5 | 65
abnormal testis morphology 5 | 43
decreased circulating serum al... 5 | 82
decreased lymphocyte cell numb... 5 | 83
decreased mean corpuscular vol... 5 | 79
increased or absent threshold ... 5 | 101
abnormal cranium morphology 4 | 36
abnormal eye morphology 4 | 68
abnormal lung morphology 4 | 26
abnormal retina morphology 4 | 71
abnormal tooth morphology 4 | 24
decreased blood urea nitrogen ... 4 | 51
decreased bone mineral density 4 | 126
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
decreased circulating triglyce... 4 | 79
decreased neutrophil cell numb... 4 | 42
impaired glucose tolerance 4 | 75
increased bone mineral content 4 | 108
increased circulating triglyce... 4 | 42
increased startle reflex 4 | 112
mammalian phenotype 4 | 17
persistence of hyaloid vascula... 4 | 33
small superior vagus ganglion 4 | 74
small testis 4 | 58
abnormal bone mineralization 3 | 38
abnormal humerus morphology 3 | 11
abnormal radius morphology 3 | 8
abnormal skin morphology 3 | 50
abnormal sleep behavior 3 | 70
abnormal tail morphology 3 | 25
abnormal tibia morphology 3 | 14
abnormal ulna morphology 3 | 8
decreased circulating free fat... 3 | 31
decreased circulating insulin ... 3 | 76
decreased circulating phosphat... 3 | 27
decreased grip strength 3 | 116
decreased heart weight 3 | 27
decreased hemoglobin content 3 | 68
decreased leukocyte cell numbe... 3 | 73
decreased mean corpuscular hem... 3 | 50
decreased startle reflex 3 | 75
embryonic growth retardation 3 | 106
enlarged kidney 3 | 14
enlarged spleen 3 | 41
hyperactivity 3 | 148
impaired pupillary reflex 3 | 26
impaired righting response 3 | 26
improved glucose tolerance 3 | 79
increased bone mineral density 3 | 72
increased circulating choleste... 3 | 66
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased red blood cell distr... 3 | 34
limb grasping 3 | 41
male infertility 3 | 123
narrow eye opening 3 | 12
thrombocytopenia 3 | 56
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal liver morphology 2 | 17
abnormal skin coloration 2 | 25
abnormal vibrissa morphology 2 | 25
anophthalmia 2 | 33
corneal opacity 2 | 32
decreased circulating calcium ... 2 | 36
decreased circulating creatini... 2 | 39
decreased hematocrit 2 | 46
decreased prepulse inhibition 2 | 82
hypoactivity 2 | 132
increased circulating bilirubi... 2 | 16
increased fasted circulating g... 2 | 76
increased large unstained cell... 2 | 5
increased lean body mass 2 | 172

Disease

Carcinoma 506 | 11,493
ovarian cancer 390 | 8,520
Cancer 374 | 2,499
psoriasis 365 | 6,694
glioblastoma 328 | 5,792
osteosarcoma 305 | 7,950
lung cancer 292 | 4,740
Breast cancer 273 | 3,578
ependymoma 253 | 4,679
medulloblastoma, large-cell 249 | 6,241
invasive ductal carcinoma 245 | 2,951
atypical teratoid / rhabdoid tumor 242 | 5,112
malignant mesothelioma 241 | 3,232
pancreatic cancer 238 | 2,398
non-small cell lung cancer 230 | 2,890
lung carcinoma 228 | 2,843
Astrocytoma, Pilocytic 226 | 3,081
lung adenocarcinoma 220 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 218 | 2,955
interstitial cystitis 211 | 2,312
adult high grade glioma 208 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 197 | 2,989
cystic fibrosis 193 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 191 | 3,291
ulcerative colitis 183 | 1,819
diabetes mellitus 178 | 1,728
Kidney cancer 167 | 2,613
breast carcinoma 161 | 1,638
ductal carcinoma in situ 159 | 1,745
pituitary cancer 145 | 1,972
group 3 medulloblastoma 143 | 4,104
Autosomal recessive predisposition 140 | 1,442
oligodendroglioma 135 | 2,850
Kidney disease 134 | 430
primitive neuroectodermal tumor 131 | 3,035
primary pancreatic ductal adenocarcinoma 128 | 1,109
tuberculosis 128 | 2,010
colon cancer 119 | 1,478
subependymal giant cell astrocytoma 118 | 2,287
Liver Cirrhosis, Experimental 110 | 769
astrocytic glioma 109 | 2,597
Schizophrenia 108 | 1,160
adrenocortical carcinoma 108 | 1,428
Duchenne muscular dystrophy 105 | 601
Arthritis 104 | 290
Atopic dermatitis 102 | 952
cutaneous lupus erythematosus 102 | 1,057
Atherosclerosis 100 | 291
gastric carcinoma 100 | 807
pancreatic ductal adenocarcinoma liver metastasis 99 | 1,962
nasopharyngeal carcinoma 97 | 1,058
Breast Neoplasms 96 | 445
juvenile dermatomyositis 96 | 1,187
Mammary Neoplasms 95 | 425
Heart disease 93 | 306
Hypertension 92 | 396
group 4 medulloblastoma 92 | 1,855
autosomal dominant Emery-Dreifuss muscular dystrophy 91 | 510
Asthma 90 | 385
Obesity 89 | 678
Melanoma 87 | 711
Rheumatoid arthritis 86 | 1,191
Vascular disease 86 | 319
Coronary artery disease 84 | 268
Hypersensitivity reaction type II disease 83 | 253
Multiple Sclerosis 80 | 540
Prostatic Neoplasms 78 | 495
Lung disease 75 | 142
Cerebrovascular disease 73 | 238
Liver disease 72 | 237
Short stature 70 | 531
esophageal adenocarcinoma 70 | 737
acute quadriplegic myopathy 69 | 1,158
Alzheimer's disease 68 | 658
Hypertensive disease 68 | 292
Anemia 67 | 365
Endometriosis 67 | 540
Inflammatory bowel disease 67 | 151
Osteoporosis 67 | 363
fibroadenoma 67 | 559
Liver cancer 66 | 604
Osteoarthritis 66 | 184
Neoplasm Invasiveness 63 | 161
Skin cancer 63 | 469
pediatric high grade glioma 63 | 1,064
Lung Neoplasms 62 | 232
Stomach Neoplasms 62 | 300
Neoplasm Metastasis 61 | 168
astrocytoma 60 | 1,146
Pick disease 59 | 1,894
active ulcerative colitis 58 | 764
limb girdle muscular dystrophy 2A 56 | 213
Pulmonary Fibrosis 55 | 106
periodontitis 55 | 293
Dermatitis 54 | 157
Bipolar Disorder 53 | 666
Carcinoma, Hepatocellular 53 | 228
Down syndrome 53 | 499
Becker muscular dystrophy 52 | 191
Intellectual disability 52 | 1,016

Tissue

Endocrine System 689 | 18,159
Digestive Tract 677 | 17,369
Female tissues 674 | 17,400
Skin and soft tissues 670 | 17,230
Male tissues 668 | 17,142
Blood and immune system 660 | 16,909
Urinary Tract 660 | 16,678
Liver and Pancreas 654 | 16,750
Nervous System 651 | 16,725
Respiratory system 635 | 16,393
Cardiovascular System 579 | 15,192

Target Family

Non-IDG 503 | 12,091
Enzyme 124 | 4,145
Kinase 37 | 634
Transcription Factor 37 | 1,400
GPCR 4 | 408
Ion Channel 3 | 344
Nuclear Receptor 3 | 48
Epigenetic 1 | 242
Transporter 1 | 473

Compartment GO Term

Extracellular matrix 713 | 713
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Amelogenin, X isoform AMELX Tbio Non-IDG -2.84702 695.0 136
Amelogenin, Y isoform AMELY Tbio Non-IDG -2.86429 712.3 22
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
A disintegrin and metalloproteinase with thrombospondin motifs 2 ADAMTS2 Tbio Enzyme -2.51717 1472.5 133