Development Level

Tbio 1,975 | 10,625
Tchem 454 | 1,890
Tdark 282 | 7,003
Tclin 118 | 602

Collection

Eligible Ion Channel Proteins 13 | 117
Eligible Kinase Proteins 7 | 134
Eligible non-olfactory GPCR Proteins 5 | 143

IMPC Term

preweaning lethality, complete... 112 | 633
abnormal behavior 46 | 226
preweaning lethality, incomple... 43 | 260
decreased lean body mass 42 | 195
embryonic lethality prior to t... 41 | 187
decreased total body fat amoun... 36 | 186
embryonic lethality prior to o... 34 | 148
decreased bone mineral content 29 | 157
decreased grip strength 28 | 123
increased circulating alkaline... 28 | 119
increased or absent threshold ... 27 | 128
abnormal bone structure 26 | 131
enlarged heart 26 | 111
decreased body weight 25 | 174
decreased body length 23 | 108
decreased bone mineral density 23 | 126
abnormal embryo size 21 | 112
hyperactivity 21 | 108
hypoactivity 21 | 89
increased mean corpuscular vol... 21 | 91
abnormal retina morphology 20 | 100
increased mean corpuscular hem... 20 | 93
short tibia 20 | 82
decreased circulating insulin ... 19 | 75
abnormal lens morphology 17 | 73
decreased mean corpuscular vol... 16 | 50
impaired glucose tolerance 16 | 52
increased lean body mass 16 | 107
decreased circulating glucose ... 15 | 121
increased bone mineral content 15 | 92
abnormal bone mineralization 14 | 55
decreased circulating triglyce... 14 | 83
increased exploration in new e... 14 | 56
decreased circulating HDL chol... 13 | 77
decreased hemoglobin content 13 | 53
improved glucose tolerance 13 | 56
increased fasted circulating g... 13 | 68
abnormal retinal pigmentation 12 | 61
abnormal seminal vesicle morph... 12 | 47
increased blood urea nitrogen ... 12 | 44
increased grip strength 12 | 83
decreased circulating serum al... 11 | 79
decreased erythrocyte cell num... 11 | 43
decreased leukocyte cell numbe... 11 | 54
decreased startle reflex 11 | 48
abnormal heart morphology 10 | 51
decreased circulating choleste... 10 | 85
decreased threshold for audito... 10 | 32
increased circulating sodium l... 10 | 71
male infertility 10 | 62
prenatal lethality prior to he... 10 | 64
abnormal QRS complex 9 | 25
abnormal neural tube closure 9 | 37
decreased circulating alkaline... 9 | 41
decreased heart weight 9 | 44
decreased mean corpuscular hem... 9 | 34
cardiovascular system phenotyp... 8 | 35
decreased caudal vertebrae num... 8 | 49
decreased eosinophil cell numb... 8 | 41
decreased lumbar vertebrae num... 8 | 62
decreased prepulse inhibition 8 | 52
decreased rib number 8 | 59
enlarged epididymis 8 | 27
increased bone mineral density 8 | 52
increased circulating chloride... 8 | 43
increased heart weight 8 | 37
increased hematocrit 8 | 36
increased sacral vertebrae num... 8 | 62
small testis 8 | 37
abnormal cranium morphology 7 | 32
abnormal kidney morphology 7 | 30
corneal opacity 7 | 25
decreased circulating alanine ... 7 | 53
immune system phenotype 7 | 17
increased hemoglobin content 7 | 45
increased leukocyte cell numbe... 7 | 37
increased red blood cell distr... 7 | 21
increased total body fat amoun... 7 | 57
thrombocytopenia 7 | 46
abnormal body wall morphology 6 | 7
abnormal cornea morphology 6 | 24
abnormal epididymis morphology 6 | 31
abnormal skin morphology 6 | 23
abnormal sleep behavior 6 | 63
abnormal testis morphology 6 | 30
decreased circulating free fat... 6 | 39
decreased circulating glycerol... 6 | 19
decreased circulating total pr... 6 | 41
decreased fasted circulating g... 6 | 49
enlarged lymph nodes 6 | 27
enlarged spleen 6 | 26
increased body weight 6 | 42
increased circulating iron lev... 6 | 25
abnormal coat/hair pigmentatio... 5 | 54
abnormal gait 5 | 51
abnormal lung morphology 5 | 15
abnormal spleen morphology 5 | 36
decreased neutrophil cell numb... 5 | 37
increased circulating potassiu... 5 | 31
increased circulating total pr... 5 | 20

Disease

ovarian cancer 1,577 | 8,484
psoriasis 1,229 | 6,685
osteosarcoma 1,215 | 7,933
glioblastoma 958 | 5,572
medulloblastoma, large-cell 956 | 6,234
lung cancer 942 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 693 | 3,289
Cancer 681 | 2,346
atypical teratoid / rhabdoid tumor 676 | 4,369
invasive ductal carcinoma 627 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 625 | 2,956
malignant mesothelioma 618 | 3,162
Breast cancer 617 | 3,094
pancreatic cancer 614 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 613 | 2,988
lung adenocarcinoma 595 | 2,713
non-small cell lung cancer 585 | 2,798
lung carcinoma 581 | 2,844
pilocytic astrocytoma 574 | 3,086
interstitial cystitis 472 | 2,299
pediatric high grade glioma 471 | 2,712
ulcerative colitis 470 | 2,087
oligodendroglioma 459 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 459 | 1,795
diabetes mellitus 455 | 1,663
primitive neuroectodermal tumor 448 | 3,031
subependymal giant cell astrocytoma 434 | 2,287
Multiple myeloma 421 | 1,327
ependymoma 420 | 2,514
breast carcinoma 384 | 1,614
ductal carcinoma in situ 380 | 1,745
cystic fibrosis 379 | 1,665
primary pancreatic ductal adenocarcinoma 362 | 1,271
astrocytoma 346 | 1,493
Carcinoma 343 | 2,147
tuberculosis 342 | 1,557
colon cancer 340 | 1,475
pituitary cancer 337 | 1,972
astrocytic glioma 335 | 2,241
Pick disease 327 | 1,893
adult high grade glioma 319 | 2,148
group 3 medulloblastoma 307 | 2,254
group 4 medulloblastoma 297 | 1,875
posterior fossa group A ependymoma 275 | 1,511
acute quadriplegic myopathy 271 | 1,157
juvenile dermatomyositis 271 | 1,189
Waldenstrons macroglobulinemia 256 | 765
adrenocortical carcinoma 255 | 1,427
Rheumatoid Arthritis 254 | 1,160
esophageal adenocarcinoma 244 | 737
dermatomyositis 240 | 933
sonic hedgehog group medulloblastoma 240 | 1,482
medulloblastoma 238 | 1,524
Duchenne muscular dystrophy 233 | 602
nasopharyngeal carcinoma 230 | 1,056
cutaneous lupus erythematosus 223 | 1,056
Atopic dermatitis 215 | 944
gastric carcinoma 213 | 832
spina bifida 192 | 1,064
active Crohn's disease 187 | 918
posterior fossa group B ependymoma 176 | 1,530
atypical teratoid/rhabdoid tumor 173 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 168 | 499
Kidney disease 157 | 396
Prostatic Neoplasms 153 | 471
acute myeloid leukemia 152 | 780
non primary Sjogren syndrome sicca 149 | 840
Down syndrome 148 | 548
primary Sjogren syndrome 143 | 789
Alzheimer's disease 137 | 644
Obesity 135 | 616
aldosterone-producing adenoma 128 | 664
fibroadenoma 128 | 557
IGA Glomerulonephritis 125 | 454
mucosa-associated lymphoid tissue lymphoma 125 | 480
Multiple Sclerosis 121 | 498
active ulcerative colitis 119 | 477
nephrosclerosis 119 | 329
pancreatic carcinoma 117 | 567
progressive supranuclear palsy 116 | 674
Arthritis 112 | 248
Hypersensitivity reaction type II disease 106 | 235
non-small cell lung carcinoma 102 | 413
Endometriosis 101 | 535
Anemia 98 | 252
tuberculosis and treatment for 6 months 98 | 686
Neurodegenerative disease 97 | 383
Hypertension 94 | 287
Becker muscular dystrophy 93 | 187
Vascular disease 92 | 281
Intellectual disability 91 | 573
Liver disease 91 | 219
Mammary Neoplasms 91 | 410
Atherosclerosis 90 | 275
Ankylosing spondylitis 87 | 138
chronic rhinosinusitis 87 | 512
Stomach Neoplasms 86 | 282
hepatocellular carcinoma 86 | 532
Polycystic Ovary Syndrome 84 | 332
Schizophrenia 83 | 501

Tissue

Female tissues 2,722 | 18,647
Nervous System 2,721 | 18,561
Digestive Tract 2,720 | 18,473
Urinary Tract 2,717 | 18,444
Endocrine System 2,715 | 18,512
Liver and Pancreas 2,715 | 18,136
Blood and immune system 2,711 | 17,995
Cardiovascular System 2,709 | 17,958
Male tissues 2,709 | 17,969
Respiratory system 2,693 | 17,484
Skin and soft tissues 2,677 | 18,115

Target Family

Non-IDG 1,655 | 11,971
Enzyme 925 | 4,146
Kinase 89 | 634
Transporter 78 | 473
Ion Channel 34 | 341
Transcription Factor 19 | 1,400
GPCR 14 | 406
Epigenetic 13 | 242
Nuclear Receptor 1 | 48
oGPCR 1 | 421

Compartment GO Term

Extracellular exosome 2,829 | 2,829
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Antileukoproteinase SLPI Tbio Enzyme -2.56514 434.2 290
Endoplasmin HSP90B1 Tchem Non-IDG -2.72785 604.5 748