Development Level

Tbio 79 | 11,651
Tchem 14 | 1,388
Tclin 11 | 612
Tdark 4 | 6,593

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 5 | 278
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
preweaning lethality, incomple... 3 | 499
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
hyperactivity 2 | 148
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating creatini... 2 | 38
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
prenatal lethality prior to he... 2 | 87
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal clavicle morphology 1 | 6
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
absent spleen 1 | 3
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased startle reflex 1 | 112
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
prolonged ST segment 1 | 36

Disease

Carcinoma 73 | 11,493
ovarian cancer 57 | 8,520
osteosarcoma 53 | 7,950
Cancer 47 | 2,499
glioblastoma 44 | 5,792
psoriasis 43 | 6,694
ependymoma 34 | 4,679
malignant mesothelioma 32 | 3,232
lung cancer 31 | 4,740
medulloblastoma, large-cell 30 | 6,241
Autosomal recessive predisposition 29 | 1,442
group 3 medulloblastoma 28 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
lung carcinoma 27 | 2,843
pancreatic cancer 27 | 2,398
Breast cancer 26 | 3,578
non-small cell lung cancer 26 | 2,890
Astrocytoma, Pilocytic 25 | 3,081
atypical teratoid / rhabdoid tumor 25 | 5,112
interstitial cystitis 25 | 2,312
adult high grade glioma 24 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
lung adenocarcinoma 22 | 2,716
invasive ductal carcinoma 21 | 2,951
cystic fibrosis 20 | 1,696
tuberculosis 20 | 2,010
ulcerative colitis 20 | 1,819
Kidney disease 19 | 430
astrocytic glioma 19 | 2,597
diabetes mellitus 19 | 1,728
oligodendroglioma 19 | 2,850
subependymal giant cell astrocytoma 19 | 2,287
breast carcinoma 17 | 1,638
Hypertension 16 | 396
Multiple myeloma 16 | 1,332
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Liver Cirrhosis, Experimental 15 | 769
Hypertensive disease 14 | 292
Kidney cancer 14 | 2,613
pituitary cancer 14 | 1,972
acute quadriplegic myopathy 13 | 1,158
cutaneous lupus erythematosus 13 | 1,057
dermatomyositis 13 | 966
ductal carcinoma in situ 13 | 1,745
esophageal adenocarcinoma 13 | 737
juvenile dermatomyositis 13 | 1,187
nasopharyngeal carcinoma 13 | 1,058
primary pancreatic ductal adenocarcinoma 13 | 1,109
Diarrhea 12 | 253
Intellectual disability 12 | 1,016
Prostatic Neoplasms 12 | 495
gastric carcinoma 12 | 807
Duchenne muscular dystrophy 11 | 601
Obesity 11 | 678
Pick disease 11 | 1,894
Schizophrenia 11 | 1,160
Waldenstrons macroglobulinemia 11 | 765
spina bifida 11 | 1,074
Epilepsy 10 | 792
Hypersensitivity reaction type II disease 10 | 253
colon cancer 10 | 1,478
Anemia 9 | 365
Atherosclerosis 9 | 291
Atopic dermatitis 9 | 952
Cognitive delay 9 | 608
Failure to gain weight 9 | 365
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
Pediatric failure to thrive 9 | 365
Seizures 9 | 596
group 4 medulloblastoma 9 | 1,855
nephrosclerosis 9 | 333
primitive neuroectodermal tumor 9 | 3,035
Barrett's esophagus 8 | 182
Coronary artery disease 8 | 268
Endometriosis 8 | 540
Hypotension 8 | 82
Kidney Diseases 8 | 114
Liver disease 8 | 237
Metabolic acidosis 8 | 90
Osteoporosis 8 | 363
Short stature 8 | 531
Stomach Neoplasms 8 | 300
Vascular disease 8 | 319
Arthritis 7 | 290
Bipolar Disorder 7 | 666
Cerebrovascular disease 7 | 238
Dull intelligence 7 | 645
Heart disease 7 | 306
Low intelligence 7 | 645
Lung disease 7 | 142
Malaria 7 | 160
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
active Crohn's disease 7 | 922
adrenocortical carcinoma 7 | 1,428
astrocytoma 7 | 1,146
pediatric high grade glioma 7 | 1,064

Tissue

Digestive Tract 107 | 17,369
Endocrine System 106 | 18,159
Female tissues 106 | 17,400
Liver and Pancreas 106 | 16,750
Male tissues 106 | 17,142
Nervous System 106 | 16,725
Urinary Tract 106 | 16,678
Blood and immune system 103 | 16,909
Skin and soft tissues 103 | 17,230
Respiratory system 102 | 16,393
Cardiovascular System 94 | 15,192

Target Family

Non-IDG 63 | 12,091
Enzyme 35 | 4,145
Ion Channel 4 | 344
Transporter 4 | 473
GPCR 1 | 408
Transcription Factor 1 | 1,400

Compartment GO Term

Extracellular exosome 108 | 108
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein wntless homolog WLS Tbio Non-IDG -2.50699 316.3 71
Sphingomyelin phosphodiesterase 3 SMPD3 Tbio Enzyme -1.84613 78.5 126
Protein argonaute-2 AGO2 Tbio Non-IDG -2.97243 867.1 202
RNA-binding protein 7 RBM7 Tbio Non-IDG -0.71461 6.57 89
Vasorin VASN Tbio Non-IDG -1.23949 17.5 130
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Programmed cell death 1 ligand 1 CD274 Tclin Non-IDG -3.53386 3285.3 993
Nuclear nucleic acid-binding protein C1D C1D Tbio Non-IDG -1.81349 69.3 176
RNA-binding motif protein, X chromosome RBMX Tbio Non-IDG -1.52402 35.8 98
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.57929 343.7 905