Development Level

Tbio 75 | 11,445
Tchem 21 | 1,598
Tclin 21 | 613
Tdark 5 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
enlarged heart 4 | 210
abnormal heart morphology 3 | 162
abnormal seminal vesicle morph... 3 | 114
embryonic growth retardation 3 | 106
enlarged uterus 3 | 11
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
hydrometra 2 | 53
increased circulating iron lev... 2 | 30
increased fasted circulating g... 2 | 76
prolonged ST segment 2 | 36
small superior vagus ganglion 2 | 74
abnormal allantois morphology 1 | 8
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal cecum morphology 1 | 7
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal left-right axis patte... 1 | 2
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal social-conspecific in... 1 | 3
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
cataract 1 | 92
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
enlarged adrenal glands 1 | 3
enlarged cecum 1 | 5
enlarged heart atrium 1 | 4
enlarged kidney 1 | 14
female infertility 1 | 60
increased CD4-positive, alpha ... 1 | 4
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
small testis 1 | 58

Disease

Carcinoma 83 | 11,493
osteosarcoma 63 | 7,950
psoriasis 59 | 6,694
lung cancer 58 | 4,740
Cancer 57 | 2,499
ovarian cancer 57 | 8,520
glioblastoma 50 | 5,792
medulloblastoma, large-cell 50 | 6,241
lung carcinoma 48 | 2,843
Breast cancer 43 | 3,578
interstitial cystitis 42 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
invasive ductal carcinoma 39 | 2,951
lung adenocarcinoma 39 | 2,716
non-small cell lung cancer 35 | 2,890
tuberculosis 35 | 2,010
diabetes mellitus 34 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
malignant mesothelioma 33 | 3,232
pancreatic cancer 33 | 2,398
ependymoma 32 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
ulcerative colitis 32 | 1,819
atypical teratoid / rhabdoid tumor 30 | 5,112
Alzheimer's disease 29 | 658
Astrocytoma, Pilocytic 29 | 3,081
Autosomal recessive predisposition 29 | 1,442
Rheumatoid arthritis 29 | 1,191
cutaneous lupus erythematosus 28 | 1,057
adult high grade glioma 27 | 3,801
Hypersensitivity reaction type II disease 26 | 253
Schizophrenia 26 | 1,160
Kidney cancer 23 | 2,613
cystic fibrosis 23 | 1,696
subependymal giant cell astrocytoma 23 | 2,287
Kidney disease 22 | 430
Liver Cirrhosis, Experimental 22 | 769
Atherosclerosis 21 | 291
Liver disease 21 | 237
Multiple Sclerosis 21 | 540
Anemia 20 | 365
ductal carcinoma in situ 20 | 1,745
breast carcinoma 19 | 1,638
group 4 medulloblastoma 19 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
pituitary cancer 19 | 1,972
mucosa-associated lymphoid tissue lymphoma 18 | 484
primary Sjogren syndrome 18 | 735
Duchenne muscular dystrophy 17 | 601
Hypertension 17 | 396
gastric carcinoma 17 | 807
primitive neuroectodermal tumor 17 | 3,035
Arthritis 16 | 290
Coronary artery disease 16 | 268
Asthma 15 | 385
Cerebrovascular disease 15 | 238
acute quadriplegic myopathy 15 | 1,158
dermatomyositis 15 | 966
juvenile dermatomyositis 15 | 1,187
sarcoidosis 15 | 370
Lung disease 14 | 142
Obesity 14 | 678
Thrombocytopenia 14 | 197
Vasculitis 14 | 80
adrenocortical carcinoma 14 | 1,428
group 3 medulloblastoma 14 | 4,104
pediatric high grade glioma 14 | 1,064
primary pancreatic ductal adenocarcinoma 14 | 1,109
Heart disease 13 | 306
Melanoma 13 | 711
Vascular disease 13 | 319
astrocytoma 13 | 1,146
head and neck cancer and chronic obstructive pulmonary disease 13 | 239
oligodendroglioma 13 | 2,850
Pneumonia 12 | 174
colon cancer 12 | 1,478
Diarrhea 11 | 253
Human immunodeficiency virus infectious disease 11 | 138
Hypertensive disease 11 | 292
astrocytic glioma 11 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
esophageal adenocarcinoma 11 | 737
periodontitis 11 | 293
Acquired immunodeficiency syndrome 10 | 197
Bipolar Disorder 10 | 666
Down syndrome 10 | 499
Fever 10 | 138
Hepatomegaly 10 | 285
Peripheral vascular disease 10 | 87
Pick disease 10 | 1,894
Splenomegaly 10 | 190
nasopharyngeal carcinoma 10 | 1,058
Epilepsy 9 | 792
Inflammatory bowel disease 9 | 151
Prostatic Neoplasms 9 | 495
active Crohn's disease 9 | 922
chronic lymphosyte leukemia 9 | 204
gastric cancer 9 | 459
pancreatic carcinoma 9 | 562
spina bifida 9 | 1,074

Tissue

Endocrine System 113 | 18,159
Female tissues 110 | 17,400
Digestive Tract 109 | 17,369
Liver and Pancreas 109 | 16,750
Skin and soft tissues 109 | 17,230
Blood and immune system 108 | 16,909
Male tissues 107 | 17,142
Urinary Tract 107 | 16,678
Respiratory system 106 | 16,393
Nervous System 104 | 16,725
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 92 | 12,091
Enzyme 15 | 4,145
GPCR 4 | 408
Ion Channel 4 | 344
Kinase 4 | 634
Transporter 3 | 473

Compartment GO Term

External side of plasma membra... 122 | 122
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.93036 825.2 985
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Ephrin type-A receptor 5 EPHA5 Tchem Kinase -2.28294 191.7 407