Development Level

Tbio 59 | 10,625
Tchem 26 | 1,890
Tclin 18 | 602
Tdark 13 | 7,003

Collection

GPCR: IDG Consortium (Targets) 1 | 128

IMPC Phenotype

enlarged heart 4 | 111
preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 3 | 260
abnormal heart morphology 2 | 51
increased fasted circulating g... 2 | 68
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 226
abnormal epididymis morphology 1 | 31
abnormal kidney morphology 1 | 30
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal social-conspecific in... 1 | 3
corneal opacity 1 | 25
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased circulating insulin ... 1 | 75
decreased fasted circulating g... 1 | 49
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged adrenal glands 1 | 3
enlarged heart atrium 1 | 2
enlarged kidney 1 | 7
enlarged uterus 1 | 3
female infertility 1 | 34
hydrometra 1 | 13
increased CD4-positive, alpha ... 1 | 15
increased bone mineral content 1 | 92
increased exploration in new e... 1 | 56
increased leukocyte cell numbe... 1 | 37
increased vertical activity 1 | 18
irregularly shaped pupil 1 | 7
male infertility 1 | 62
polycystic kidney 1 | 9
straub tail 1 | 26

Disease

osteosarcoma 58 | 7,933
psoriasis 53 | 6,685
Cancer 50 | 2,346
ovarian cancer 48 | 8,491
lung cancer 47 | 4,473
lung carcinoma 45 | 2,844
medulloblastoma, large-cell 42 | 6,234
glioblastoma 40 | 5,572
lung adenocarcinoma 36 | 2,714
interstitial cystitis 35 | 2,299
diabetes mellitus 34 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,956
invasive ductal carcinoma 31 | 2,950
Breast cancer 30 | 3,098
non-small cell lung cancer 30 | 2,798
pancreatic cancer 29 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
ulcerative colitis 28 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,289
malignant mesothelioma 27 | 3,163
pilocytic astrocytoma 27 | 3,086
Rheumatoid Arthritis 26 | 1,170
tuberculosis 26 | 1,563
cutaneous lupus erythematosus 25 | 1,056
Atherosclerosis 23 | 275
Hypersensitivity reaction type II disease 23 | 235
Kidney disease 23 | 397
pediatric high grade glioma 23 | 2,712
Alzheimer's disease 22 | 644
cystic fibrosis 22 | 1,670
Liver disease 21 | 219
atypical teratoid / rhabdoid tumor 20 | 4,369
Multiple Sclerosis 19 | 498
ductal carcinoma in situ 19 | 1,745
group 4 medulloblastoma 19 | 1,875
subependymal giant cell astrocytoma 19 | 2,287
Hypertension 18 | 293
Anemia 17 | 252
breast carcinoma 17 | 1,614
gastric carcinoma 17 | 832
pituitary cancer 17 | 1,972
primitive neuroectodermal tumor 17 | 3,031
Coronary artery disease 16 | 240
Carcinoma 15 | 2,147
mucosa-associated lymphoid tissue lymphoma 15 | 480
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
primary Sjogren syndrome 15 | 788
primary pancreatic ductal adenocarcinoma 15 | 1,271
sarcoidosis 15 | 368
Asthma 14 | 349
Cerebrovascular disease 14 | 231
dermatomyositis 14 | 966
juvenile dermatomyositis 14 | 1,189
Duchenne muscular dystrophy 13 | 602
Lung disease 13 | 136
acute quadriplegic myopathy 13 | 1,157
adrenocortical carcinoma 13 | 1,427
posterior fossa group B ependymoma 13 | 1,530
Heart disease 12 | 279
Obesity 12 | 616
Thrombocytopenia 12 | 105
Vasculitis 12 | 64
adult high grade glioma 12 | 2,148
oligodendroglioma 11 | 2,849
Hepatitis C 10 | 90
Metabolic syndrome X 10 | 155
Peripheral vascular disease 10 | 90
astrocytoma 10 | 1,493
atypical teratoid/rhabdoid tumor 10 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
ependymoma 10 | 2,514
esophageal adenocarcinoma 10 | 737
Acquired immunodeficiency syndrome 9 | 164
IGA Glomerulonephritis 9 | 454
Pick disease 9 | 1,893
Schizophrenia 9 | 503
Severe Combined Immunodeficiency 9 | 46
active Crohn's disease 9 | 918
astrocytic glioma 9 | 2,241
head and neck cancer and chronic obstructive pulmonary disease 9 | 237
nasopharyngeal carcinoma 9 | 1,056
periodontitis 9 | 269
Autistic Disorder 8 | 320
Down syndrome 8 | 548
Fatty liver disease 8 | 86
Hepatitis B 8 | 103
Human immunodeficiency virus infectious disease 8 | 129
Hypertensive disease 8 | 193
Inflammatory bowel disease 8 | 142
Pneumonia 8 | 133
Prostatic Neoplasms 8 | 471
Vascular disease 8 | 281
colon cancer 8 | 1,475
nephrosclerosis 8 | 329
posterior fossa group A ependymoma 8 | 1,511
Atopic dermatitis 7 | 944
fibroadenoma 7 | 557
gastric cancer 7 | 436
sonic hedgehog group medulloblastoma 7 | 1,482
spina bifida 7 | 1,064

Tissue

Endocrine System 106 | 18,511
Female tissues 106 | 18,646
Nervous System 106 | 18,560
Urinary Tract 106 | 18,443
Cardiovascular System 105 | 17,957
Digestive Tract 105 | 18,472
Respiratory system 105 | 17,483
Blood and immune system 104 | 17,994
Liver and Pancreas 104 | 18,135
Male tissues 104 | 17,968
Skin and soft tissues 104 | 18,114

Target Family

Non-IDG 79 | 11,969
Enzyme 24 | 4,146
GPCR 4 | 408
Ion Channel 3 | 341
Kinase 3 | 634
Transporter 3 | 473

Compartment GO Term

External side of plasma membra... 116 | 116
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.04462 893.1 512
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.81736 519.3 441
Platelet-activating factor receptor PTAFR Tchem GPCR -1.98455 106.0 120
Ig lambda-6 chain C region IGLC6 Tdark Non-IDG -1.81183 228.7 0
H(+)/Cl(-) exchange transporter 3 CLCN3 Tchem Ion Channel -2.25773 194.9 155
Folate receptor beta FOLR2 Tchem Non-IDG -1.86286 82.1 165
Gamma-glutamyltransferase light chain 1 GGTLC1 Tdark Enzyme 0.06 0.65 32
Fc receptor-like protein 6 FCRL6 Tdark Non-IDG -0.43556 3.46 29
Fibrocystin PKHD1 Tbio Non-IDG -1.70977 478.8 63