Development Level

Tbio 28 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 2 | 278
abnormal clavicle morphology 1 | 6
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal rib morphology 1 | 10
decreased circulating insulin ... 1 | 76
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
increased anti-nuclear antigen... 1 | 19
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87

Disease

osteosarcoma 25 | 7,950
Carcinoma 19 | 11,493
ovarian cancer 17 | 8,520
group 3 medulloblastoma 9 | 4,104
medulloblastoma, large-cell 9 | 6,241
psoriasis 8 | 6,694
Kidney cancer 7 | 2,613
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Breast cancer 4 | 3,578
Pick disease 4 | 1,894
Pontocerebellar hypoplasia 4 | 36
colon cancer 4 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
Autosomal recessive predisposition 3 | 1,442
Lung adenoma 3 | 8
Multiple myeloma 3 | 1,332
Perlman syndrome 3 | 9
adrenocortical carcinoma 3 | 1,428
ependymoma 3 | 4,679
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
tuberculosis 3 | 2,010
Amyotrophic lateral sclerosis type 4 2 | 5
Calcinosis 2 | 70
Cerebral atrophy 2 | 178
Cognitive delay 2 | 608
Dyskeratosis congenita 2 | 24
Failure to gain weight 2 | 365
Feeding difficulties 2 | 127
Global developmental delay 2 | 608
Mental and motor retardation 2 | 608
Myositis 2 | 30
Neurodegenerative disease 2 | 414
Pediatric failure to thrive 2 | 365
Polyhydramnios 2 | 108
Pontocerebellar Hypoplasia Type 1 2 | 5
Rheumatoid arthritis 2 | 1,191
Systemic scleroderma 2 | 60
X-linked cerebral adrenoleukodystrophy 2 | 116
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
hepatocellular carcinoma 2 | 547
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
Abnormal urinary amino-acid findings 1 | 38
Achondroplasia 1 | 21
Acute stress disorder 1 | 6
Afro-textured hair 1 | 13
Alveolar echinococcosis 1 | 7
Aminoaciduria 1 | 38
Asphyxiating thoracic dystrophy 1 | 44
Autosomal dominant Robinow syndrome 1 1 | 15
Brittle hair 1 | 25
Cerebellar cyst 1 | 5
Chronic Kidney Diseases 1 | 13
Delayed epiphyseal ossification 1 | 10
Delayed maturation of end part of long bone 1 | 10
Dent disease 1 | 18
Dubowitz syndrome 1 | 13
Ebola hemorrhagic fever 1 | 13
Fractured hair 1 | 25
Fragile hair 1 | 25
Glycosuria 1 | 29
Goiter 1 | 38
Hemophagocytic lymphohistiocytosis 1 | 30
Hepatitis 1 | 67
Hypercalciuria 1 | 27
Hyperphosphaturia 1 | 21
Increased calcium level in kidney 1 | 21
Kinky hair texture 1 | 13
Lassa fever 1 | 9
Metaphyseal irregularity 1 | 23
Microscopic hematuria 1 | 9
Mouth disease 1 | 7
Nappy hair texture 1 | 13
Poor head control 1 | 14
Precancerous Conditions 1 | 80
Progressive microcephaly 1 | 32
Progressive renal failure 1 | 13
Reduced tensile strength of hair 1 | 25
Retinitis pigmentosa 24 1 | 15
Skin Abnormalities 1 | 37
Tubular atrophy 1 | 10
Visceral leishmaniasis 1 | 14
cat-scratch disease 1 | 9

Tissue

Blood and immune system 33 | 16,909
Cardiovascular System 33 | 15,192
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678

Target Family

Enzyme 19 | 4,145
Non-IDG 13 | 12,091
Ion Channel 1 | 344

Compartment GO Term

Exoribonuclease complex 33 | 33
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Exosome component 10 EXOSC10 Tbio Non-IDG -2.45249 279.1 123
Exosome complex exonuclease RRP44 DIS3 Tbio Enzyme -1.80730 64.2 141
Exosome complex component RRP4 EXOSC2 Tbio Non-IDG -0.28065 2.13 121
5'-3' exoribonuclease 2 XRN2 Tbio Enzyme -1.52792 31.8 121
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.13482 125.3 51
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.19402 16.8 65
Nuclear inhibitor of protein phosphatase 1 PPP1R8 Tbio Enzyme -2.70517 500.3 281
Exosome complex component MTR3 EXOSC6 Tbio Enzyme -0.78888 5.11 84
Exosome complex component RRP41 EXOSC4 Tbio Enzyme -1.96200 85.3 113
DIS3-like exonuclease 1 DIS3L Tdark Enzyme -0.68418 3.89 94