Development Level

Tbio 106 | 10,625
Tchem 19 | 1,890
Tdark 12 | 7,003
Tclin 9 | 602

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

abnormal behavior 8 | 226
preweaning lethality, complete... 7 | 633
decreased grip strength 6 | 123
decreased bone mineral content 4 | 157
decreased lean body mass 4 | 195
hypoactivity 4 | 89
decreased total body fat amoun... 3 | 186
increased circulating sodium l... 3 | 71
preweaning lethality, incomple... 3 | 260
abnormal QRS complex 2 | 25
abnormal epididymis morphology 2 | 31
abnormal retinal pigmentation 2 | 61
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating insulin ... 2 | 75
decreased vertical activity 2 | 22
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
enlarged epididymis 2 | 27
increased circulating chloride... 2 | 43
increased erythrocyte cell num... 2 | 26
increased grip strength 2 | 83
increased or absent threshold ... 2 | 128
increased total body fat amoun... 2 | 57
persistence of hyaloid vascula... 2 | 22
short tibia 2 | 82
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat- hair morphology 1 | 18
abnormal coat-hair pigmentatio... 1 | 54
abnormal iris pigmentation 1 | 3
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased granulocyte number 1 | 8
decreased hemoglobin content 1 | 53
decreased late germinal center... 1 | 2
decreased monocyte cell number 1 | 28
decreased myeloid cell number ... 1 | 1
decreased neutrophil cell numb... 1 | 37
decreased pre-pro B cell numbe... 1 | 2
decreased prepulse inhibition 1 | 52
decreased pro-B cell number 1 | 2
hemorrhage 1 | 12
hyperactivity 1 | 108
immune system phenotype 1 | 17
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased T cell number 1 | 15
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased early germinal cente... 1 | 2
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased immature B cell numb... 1 | 1
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 25
increased pre-B cell number 1 | 1
increased vertical activity 1 | 18
limb grasping 1 | 35
male infertility 1 | 62
shortened RR interval 1 | 19
small spleen 1 | 11
small superior vagus ganglion 1 | 20

Disease

medulloblastoma, large-cell 76 | 6,234
glioblastoma 74 | 5,572
ovarian cancer 68 | 8,491
osteosarcoma 66 | 7,933
pilocytic astrocytoma 65 | 3,086
oligodendroglioma 62 | 2,849
psoriasis 58 | 6,685
atypical teratoid / rhabdoid tumor 56 | 4,369
lung carcinoma 52 | 2,844
pediatric high grade glioma 52 | 2,712
primitive neuroectodermal tumor 47 | 3,031
Pick disease 46 | 1,893
astrocytoma 43 | 1,493
subependymal giant cell astrocytoma 38 | 2,287
ependymoma 31 | 2,514
lung cancer 30 | 4,473
posterior fossa group A ependymoma 28 | 1,511
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
malignant mesothelioma 26 | 3,163
group 3 medulloblastoma 25 | 2,254
Alzheimer's disease 24 | 644
Schizophrenia 24 | 503
astrocytic glioma 24 | 2,241
interstitial cystitis 24 | 2,299
Parkinson's disease 23 | 364
adult high grade glioma 23 | 2,148
invasive ductal carcinoma 23 | 2,950
group 4 medulloblastoma 21 | 1,875
medulloblastoma 21 | 1,524
pituitary cancer 21 | 1,972
posterior fossa group B ependymoma 21 | 1,530
Carcinoma 20 | 2,147
diabetes mellitus 20 | 1,663
Epilepsy 19 | 346
atypical teratoid/rhabdoid tumor 19 | 1,095
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,988
Cancer 18 | 2,346
lung adenocarcinoma 17 | 2,714
pancreatic cancer 17 | 2,300
sonic hedgehog group medulloblastoma 17 | 1,482
Neurodegenerative disease 16 | 383
Breast cancer 14 | 3,098
Tetanus 14 | 66
colon cancer 14 | 1,475
Multiple myeloma 13 | 1,327
non-small cell lung cancer 13 | 2,798
tuberculosis 13 | 1,563
ulcerative colitis 13 | 2,087
Toxic encephalopathy 12 | 131
Bipolar Disorder 11 | 266
Neuropathy 11 | 210
spina bifida 11 | 1,064
Botulism 10 | 20
Dementia 10 | 129
Intellectual disability 10 | 573
ductal carcinoma in situ 10 | 1,745
Amyotrophic Lateral Sclerosis 9 | 432
Autistic Disorder 9 | 320
Cerebrovascular disease 9 | 231
Diarrhea 9 | 155
Huntington's disease 9 | 72
Obesity 9 | 616
Parkinson Disease 9 | 105
cutaneous lupus erythematosus 9 | 1,056
cystic fibrosis 9 | 1,670
pancreatic carcinoma 9 | 567
Cocaine-Related Disorders 8 | 88
nasopharyngeal carcinoma 8 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Asthma 7 | 349
Brain disease 7 | 84
Hypertension 7 | 293
Inflammatory bowel disease 7 | 142
Rheumatoid Arthritis 7 | 1,170
Waldenstrons macroglobulinemia 7 | 764
adrenocortical carcinoma 7 | 1,427
glioblastoma multiforme 7 | 347
primary pancreatic ductal adenocarcinoma 7 | 1,271
urothelial carcinoma 7 | 318
Anemia 6 | 252
Down syndrome 6 | 548
Gaucher disease type 1 6 | 171
Irritable bowel syndrome 6 | 59
Kidney disease 6 | 397
Nerve Degeneration 6 | 73
REM sleep behavior disorder 6 | 16
Seizures 6 | 95
active ulcerative colitis 6 | 477
acute quadriplegic myopathy 6 | 1,157
aldosterone-producing adenoma 6 | 664
breast carcinoma 6 | 1,614
dermatomyositis 6 | 966
juvenile dermatomyositis 6 | 1,189
non primary Sjogren syndrome sicca 6 | 840
Endometriosis 5 | 535
acute myeloid leukemia 5 | 785
esophageal adenocarcinoma 5 | 737
fibroadenoma 5 | 557
gastric cancer 5 | 436

Tissue

Endocrine System 145 | 18,511
Female tissues 145 | 18,646
Nervous System 145 | 18,560
Digestive Tract 144 | 18,472
Skin and soft tissues 144 | 18,114
Cardiovascular System 143 | 17,957
Liver and Pancreas 143 | 18,135
Urinary Tract 143 | 18,443
Blood and immune system 142 | 17,994
Male tissues 141 | 17,968
Respiratory system 139 | 17,483

Target Family

Non-IDG 104 | 11,969
Enzyme 20 | 4,146
Transporter 14 | 473
Ion Channel 3 | 341
GPCR 2 | 408
Kinase 2 | 634
Epigenetic 1 | 242

Compartment GO Term

Exocytic vesicle 146 | 146
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91708 86.7 133
D(2) dopamine receptor DRD2 Tclin GPCR -3.26127 1775.2 248
Synaptotagmin-7 SYT7 Tbio Non-IDG -1.72363 48.4 144
Ras-related protein Rab-27A RAB27A Tbio Enzyme -2.26523 184.9 247
H(+)/Cl(-) exchange transporter 3 CLCN3 Tchem Ion Channel -2.25773 194.9 155
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.98538 103.1 38
Vesicle-associated membrane protein 2 VAMP2 Tbio Non-IDG -2.50812 310.3 171
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.74048 58.0 91
Orexin HCRT Tbio Non-IDG -3.24848 2104.5 162
Synaptogyrin-4 SYNGR4 Tdark Non-IDG 0.00000 110