Development Level

Tbio 132 | 11,445
Tchem 17 | 1,598
Tdark 16 | 6,588
Tclin 11 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 7 | 499
abnormal behavior 6 | 298
decreased bone mineral content 5 | 151
embryonic lethality prior to t... 5 | 278
abnormal sleep behavior 4 | 70
decreased total body fat amoun... 4 | 207
increased circulating sodium l... 4 | 71
abnormal behavioral response t... 3 | 66
abnormal retina morphology 3 | 71
decreased body length 3 | 101
decreased bone mineral density 3 | 126
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
hypoactivity 3 | 132
abnormal seminal vesicle morph... 2 | 114
abnormal testis morphology 2 | 43
convulsive seizures 2 | 13
decreased circulating insulin ... 2 | 76
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
increased total body fat amoun... 2 | 134
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
short tibia 2 | 97
small spleen 2 | 19
small testis 2 | 58
tremors 2 | 39
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal iris pigmentation 1 | 4
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged kidney 1 | 14
enlarged urinary bladder 1 | 8
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating LDL chol... 1 | 13
increased circulating potassiu... 1 | 29
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Carcinoma 111 | 11,493
glioblastoma 92 | 5,792
medulloblastoma, large-cell 92 | 6,241
ependymoma 90 | 4,679
atypical teratoid / rhabdoid tumor 84 | 5,112
ovarian cancer 81 | 8,520
osteosarcoma 79 | 7,950
Astrocytoma, Pilocytic 77 | 3,081
adult high grade glioma 77 | 3,801
oligodendroglioma 72 | 2,850
group 3 medulloblastoma 71 | 4,104
psoriasis 66 | 6,694
astrocytic glioma 61 | 2,597
Pick disease 56 | 1,894
lung carcinoma 56 | 2,843
primitive neuroectodermal tumor 56 | 3,035
subependymal giant cell astrocytoma 42 | 2,287
Schizophrenia 37 | 1,160
lung cancer 36 | 4,740
malignant mesothelioma 33 | 3,232
Alzheimer's disease 31 | 658
invasive ductal carcinoma 31 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
Parkinson's disease 28 | 392
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
Breast cancer 27 | 3,578
Epilepsy 26 | 792
Kidney cancer 26 | 2,613
interstitial cystitis 26 | 2,312
pancreatic cancer 24 | 2,398
pituitary cancer 24 | 1,972
Bipolar Disorder 23 | 666
diabetes mellitus 23 | 1,728
Cancer 22 | 2,499
Depressive disorder 21 | 409
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
tuberculosis 21 | 2,010
Intellectual disability 20 | 1,016
group 4 medulloblastoma 20 | 1,855
lung adenocarcinoma 20 | 2,716
astrocytoma 19 | 1,146
non-small cell lung cancer 19 | 2,890
Mental Depression 18 | 333
Neurodegenerative disease 17 | 414
ductal carcinoma in situ 17 | 1,745
Dementia 16 | 175
Multiple myeloma 16 | 1,332
Alcoholic Intoxication, Chronic 15 | 289
Seizures 15 | 596
Tetanus 15 | 68
Toxic encephalopathy 15 | 141
colon cancer 15 | 1,478
Autosomal recessive predisposition 14 | 1,442
ulcerative colitis 14 | 1,819
Amyotrophic lateral sclerosis 13 | 451
Neuropathy 12 | 261
Cerebrovascular disease 11 | 238
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
cutaneous lupus erythematosus 11 | 1,057
juvenile dermatomyositis 11 | 1,187
primary pancreatic ductal adenocarcinoma 11 | 1,109
Autistic Disorder 10 | 364
Botulism 10 | 24
Brain disease 10 | 96
Dysarthria 10 | 192
Huntington's disease 10 | 76
Liver cancer 10 | 604
Major Depressive Disorder 10 | 301
Melanoma 10 | 711
active ulcerative colitis 10 | 764
cystic fibrosis 10 | 1,696
nasopharyngeal carcinoma 10 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
pediatric high grade glioma 10 | 1,064
spina bifida 10 | 1,074
Attention deficit hyperactivity disorder 9 | 278
Blepharoptosis 9 | 231
Dystonia 9 | 164
Griscelli syndrome 9 | 24
Hypertension 9 | 396
Parkinsonian Disorders 9 | 56
Rheumatoid arthritis 9 | 1,191
Skin cancer 9 | 469
aldosterone-producing adenoma 9 | 665
pancreatic carcinoma 9 | 562
Cocaine-Related Disorders 8 | 92
Cognitive delay 8 | 608
Diarrhea 8 | 253
Down syndrome 8 | 499
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Nerve Degeneration 8 | 121
Obesity 8 | 678
Waldenstrons macroglobulinemia 8 | 765
adrenocortical carcinoma 8 | 1,428
dermatomyositis 8 | 966

Tissue

Endocrine System 168 | 18,159
Digestive Tract 166 | 17,369
Nervous System 164 | 16,725
Female tissues 162 | 17,400
Male tissues 162 | 17,142
Skin and soft tissues 161 | 17,230
Liver and Pancreas 160 | 16,750
Urinary Tract 154 | 16,678
Respiratory system 152 | 16,393
Blood and immune system 151 | 16,909
Cardiovascular System 138 | 15,192

Target Family

Non-IDG 124 | 12,091
Enzyme 25 | 4,145
Transporter 15 | 473
oGPCR 4 | 421
Ion Channel 3 | 344
GPCR 2 | 408
Kinase 2 | 634
Epigenetic 1 | 242

Compartment GO Term

Exocytic vesicle 176 | 176
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.93790 85.1 158
Synaptotagmin-like protein 2 SYTL2 Tbio Non-IDG -1.27949 19.5 60
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
Putative synaptogyrin-2 like protein N/A Tdark Non-IDG -0.69433 7.83 0
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Ras-related protein Rab-40C RAB40C Tbio Non-IDG -0.89913 7.57 111
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91664 86.4 148
COP9 signalosome complex subunit 4 COPS4 Tbio Non-IDG -0.91181 7.39 88